Integriculture
Integriculture is a Japanese cellular agriculture infrastructure company (founded 2015) that commercializes the CulNet® biomimetic cell culture platform, food-grade reagents (I-MEM, iDisper, iCoater), the CELLAMENT® cosmetics ingredient, and CRDMO services for enterprise food, cosmetics, and supplement partners across Japan, Singapore, and Korea.
- Company typePrivate
- Founded2015
- HeadquartersTokyo, Japan
- Headcount11–50
- GTM typeB2B
- OfferingServices
What Integriculture does
Integriculture (インテグリカルチャー株式会社) is a Tokyo- and Shonan-based cellular agriculture infrastructure company founded in October 2015 by CEO Yuki Hanyu (Oxford Ph.D., Chemistry) and CTO Ikko Kawashima (Hiroshima Ph.D., Agriculture). It develops and commercializes the CulNet® System — a biomimetic organ-interaction cell culture platform that uses connected feeder-cell bioreactors to produce serum-like growth components endogenously, eliminating the need for fetal bovine serum or exogenous growth factors and reducing culture media cost by approximately 60x versus conventional methods. Around this core platform, the company operates four branded service lines: CulNet Consortium (an open-innovation network of 15+ enterprise partners including Sumitomo Riko, EBARA, House Foods, and Hamano Products generating 10+ joint patent applications), Ocatté Base (an e-commerce marketplace for cellular agriculture materials, equipment, and starter kits targeting researchers and startups), PiPELiNE (a CRDMO service for client scale-up projects), and Cellag (an OEM/ODM brand for cosmetics and supplements).
The company monetizes through three revenue streams that were roughly evenly split in FY2025: (1) infrastructure and CRDMO services including consortium membership fees and project-based development contracts, (2) sale of proprietary cellular agriculture products — primarily the CELLAMENT® egg-derived cell culture supernatant ingredient adopted by 12+ cosmetics brands as of February 2026, food-grade I-MEM basal medium, and reagents iDisper and iCoater, and (3) e-commerce and equipment sales via Ocatté Base including Organoid Farm cell lines and co-developed production equipment (Oxy-thru Cultivator, Product Reactor, Advanced C-CulNet). Distribution is hybrid: direct enterprise sales in Japan and Singapore, exclusive distributors (Atlantis Bioscience for Singapore I-MEM, Nippon Barrier Free for 19-country marine cosmetics distribution), and self-serve e-commerce for the academic/SMB segment.
Integriculture achieved its first full-year profitability in FY2025 with ~$1.5 million revenue and ~$300K net profit, distinguishing it from most cultivated-meat peers globally. The company has raised approximately $30 million cumulatively across disclosed rounds (2018 seed, 2020 Series A led by Beyond Next Ventures, 2022 round led by AgFunder, Feb 2024 ~$14.3M round) plus JPY 240M of NEDO non-dilutive grant funding and a $1.3M Mizuho Bank loan. Recent strategic priorities are Singapore regulatory approval for cultivated meat (target end-2026 with Sumitomo Riko and Cell AgriTech), regional cellular agriculture hubs in Japan via the Niigata Food Tech Town Concept with Oisix ra Daichi, and Korean market entry following CELLAMENT's INCI registration.
Integriculture firmographics
Firmographics- Name
- Integriculture
- Legal name
- インテグリカルチャー株式会社 (IntegriCulture Inc.)
- Website
- https://integriculture.com
- Company type
- Private
- Founded year
- 2015
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Integriculture is a Japanese cellular agriculture infrastructure company (founded 2015) that commercializes the CulNet® biomimetic cell culture platform, food-grade reagents (I-MEM, iDisper, iCoater), the CELLAMENT® cosmetics ingredient, and CRDMO services for enterprise food, cosmetics, and supplement partners across Japan, Singapore, and Korea.
- Ownership category
- akta.pro rank
Integriculture industry classification
Industry- Product category
- Cellular Agriculture Infrastructure
- NAICS
- Food Manufacturing (311)
- SIC
- Food And Kindred Products (2000), Biological Products, (No Disgnostic Substances) (2836)
- akta.pro primary industry
- Cell Line Development & Banking (Food/AG Cell Lines) (AFANAKAE)
- akta.pro secondary industries
- Bioprocess Development & Scale-Up/Scale-Down Platforms (DoE, high-throughput, modeling) (HLAAAJAF), Bioprocess Consumables & Reagents (resins, membranes, media components, buffers) (HLAAAJAI), Raw Materials & Critical Reagents Supply (Media/Resins/Cytokines) (HLAGAGAI)
Keywords
Where Integriculture is headquartered
LocationHeadquarters
- HQ city
- Tokyo
- HQ country
- Japan
- HQ region
- Asia
Offices3 records
Markets served
Integriculture business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Technology or R&D, Personnel, Infrastructure, Operations, Marketing or Sales, Supply Chain
Revenue model
- Cellular Agriculture Infrastructure (CRDMO Services): Contract research, development, and manufacturing organization (CRDMO) services providing CulNet System platforms, technical support, and scale-up assistance to corporate partners. Revenue is project-based and recurring as clients advance through development stages. CulNet Consortium membership fees and pipeline project revenues contribute to this stream. Revenue was evenly split with the products business in FY2025.
- Cellular Agriculture Products (Cosmetics & Food Ingredients): Sale of cellular agriculture-derived ingredients, primarily CELLAMENT® for cosmetics, and cultured food ingredients. The cosmetics ingredient business generated approximately $300,000 profit in 2025. The company has over 12 cosmetic brand customers using CELLAMENT® as of early 2026. Food-grade basal medium I-MEM is also sold commercially.
- Consumables and Equipment Sales (Ocatté Base): E-commerce marketplace (Ocatté Base) for cellular agriculture materials, reagents, equipment, and starter kits. Targets researchers and startups entering cellular agriculture. Products include food-grade culture media, cell lines (e.g., Organoid Farm bovine myoblasts), and equipment bundles.
Go-to-market motion3 records
Distribution channels5 records
Marketing channels7 records
Integriculture product offering
Product offeringCore offering
Integriculture develops and commercializes the CulNet® System, a biomimetic organ-interaction cell culture platform that enables large-scale, low-cost animal cell culture without exogenous growth factors or fetal bovine serum. Around this core platform, the company offers CRDMO services (PiPELiNE), an open-innovation consortium (CulNet Consortium), a materials/equipment marketplace (Ocatté Base), and commercial products including the CELLAMENT® cosmetics ingredient, I-MEM food-grade basal medium, food-grade reagents (iDisper, iCoater), and production-scale bioreactors (Oxy-thru Cultivator, Product Reactor, Advanced C-CulNet).
Product overview
Integriculture operates as a cellular agriculture infrastructure platform provider rather than a single-product company. Its portfolio consists of a core technology (CulNet System) augmented by four platform services (CulNet Consortium, Ocatté Base, PiPELiNE, Cellag) and multiple commercialized ingredients and equipment. The CulNet System is the foundational technology — a universal cell culture platform that produces growth factors internally via simulated organ interactions, eliminating expensive external serum and growth factors. Around this core, the company offers: CulNet Consortium (an open-innovation partner network with 15 member companies), Ocatté Base (a marketplace for cell agriculture materials and equipment), PiPELiNE (contract R&D/manufacturing services), and Cellag (an open cosmetics/supplements brand). Commercial products include: CELLAMENT skincare ingredient (used by 12 companies including FABIUS in Cell+ finish mask), I-MEM food-grade basal medium (v1.0 and 2.0), food-grade reagents iDisper and iCoater, and production equipment including the Oxy-thru Cultivator (2L culture bag), Advanced C-CulNet (commercial serum production), and Product Reactor (demonstration-scale food production). Revenue is split evenly between the products/business segment (cosmetics ingredients, food products) and the infrastructure segment (platform services, equipment).
Differentiator
Problem solved
Functional benefit
Brands
- CulNet Consortium: Open innovation platform for cellular agriculture infrastructure with partner companies developing materials, equipment, and processes.
- Ocatté Base (勝手場)
- PiPELiNE
- Cellament (セラメント)
- I-MEM
- Oxy-thru Cultivator
- Cell+ (セルプラス)
Products and services
- CulNet Consortium Open innovation partner network for the cellular agriculture supply chain across chemicals, biologics, materials, food processing, engineering, IT, and logistics. 15+ participating companies as of September 2024.
- Ocatté Base E-commerce marketplace for cellular agriculture materials, reagents, equipment, starter kits, and cell lines targeting researchers, startups, and academic institutions globally.
- PiPELiNE (CulNet Pipeline CRDMO Service) Contract Research, Development and Manufacturing Organization (CRDMO) service for cellular agriculture products. Provides cell culture technology expertise, scale-up support, and customized cell-cultured serum to corporate partners.
- Cellag OEM/ODM Brand Open brand for cosmetics and supplements leveraging cellular agriculture; covers cosmetics ingredients and food-grade materials, supporting product formulation through to commercialization via OEM/ODM services.
- CELLAMENT® Cosmetics Ingredient Proprietary chicken egg-derived cell culture supernatant ingredient for cosmetics and skincare. Contains diverse proteins and growth factors; adopted by 12+ cosmetic brands in serums, creams, and lash serums.
- I-MEM Basal Medium All-food-grade basal medium for cell culture composed entirely of food-approved ingredients (amino acids, sugars). Available in I-MEM 1.0 (food-grade) and I-MEM 2.0 (bulk-ingredient-based) versions.
- iDisper Cell Dissociation Agent Food-additive-grade animal-free cell dissociation reagent using plant-derived papain enzyme and trisodium citrate. Equivalent efficiency to research-grade reagents; stable at -20°C for 8 months.
- iCoater Cell Culture Coating Agent Ready-to-use food-grade cell culture surface coating agent composed solely of food-grade gelatin, designed for food manufacturing conditions including heat sterilization.
- Oxy-thru Cultivator 2L cell culture bag using high-gas-permeable materials and precision molding. Achieves 1 kg/month per bag production without external oxygen injection equipment, enabling scale-out production.
- Advanced C-CulNet System Commercial-scale production unit for conditioned medium (cell-cultured serum). Designed for stable, long-term, large-scale production to reduce cell-cultured food production costs.
- Product Reactor Production-scale stirring packed-bed reactor for high-density adherent cell culture of cell-cultured food. Designed for cellular agriculture rather than repurposed from biopharma; targets 10 kg/month production capacity.
Quantifiable outcome
- Cost of culture media reduced to approximately 1/60th of conventional serum-based media when using I-MEM + CulNet System
- +5 more outcomes
Companies that use Integriculture
Customer profileNamed customers9 records
Segments5 records
Ideal customer profiles3 records
Integriculture technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature8 records
Integriculture partnerships and signals
Strategic signalPartnerships
14 partnerships are on record, tiered core and minor.
- Sumitomo Riko (住友理工)coreStrategic partnership MoU signed March 2026 to launch cultivated meat production demonstrations in Singapore. Jointly developing 'Oxy-thru Cultivator' (2L cell culture bags) via CulNet Consortium. Also jointly establishing domestic contract manufacturing services. Sumitomo Riko contributes high-gas-permeable materials and precision molding technology.
- Cell AgriTech Pte. Ltd. (Singapore)coreLocal manufacturing partner in Singapore for validation and commercial production of cultivated meat using I-MEM basal medium and Oxy-thru Cultivator. Data generated will support regulatory application to Singapore Food Agency (SFA) by end of 2026.
- Oisix ra Daichi (オイシックス・ラ・大地)coreJoint development agreement signed January 2026 for regionally-branded cellular foods under the 'Niigata Food Tech Town Concept'. Integriculture provides cell culture technology; Oisix provides marketing and product development. NSG Group joined from March 2026.
- NSG GroupcoreJoined the Niigata Food Tech Town initiative from March 2026 alongside Integriculture and Oisix ra Daichi, aiming to establish cellular agriculture as a regional revitalization tool.
- Nippon Barrier FreeminorSales and distribution partner for Umami Bioworks' cultivated marine cosmetics and supplement ingredients across Japan and 18 other countries. Builds on existing Integriculture-Umami Bioworks collaboration.
- Tsunan Sake Brewery (津南醸造)minorJoint R&D using local natural water for cell-cultured food and cosmetics ingredients. First partnership in Integriculture's nationwide 'Regional Symbiosis Model', aiming to transform sake breweries into micro-production hubs for cellular agriculture.
- Hamano Products (浜野製作所)coreCo-developed 'Product Reactor' — a production-scale stirring packed-bed reactor for cellular agriculture. Partnership since 2021 with MAFF SBIR support. Successfully produced cell-cultured food paste targeting 10 kg/month production.
- FABIUS (ファビウス)coreCo-developed and launched 'Cell+' finish mask using CELLAMENT® ingredient. Clinical research conducted and published in medical journal 'Advanced Medical Research and Health Beauty'. Product launched October 2025.
- Umami Bioworks (Singapore)coreMoU signed August 2025 for fish cell culture cosmetics development. Umami Bioworks is developing cultivated marine ingredients using Integriculture's technology. Distribution via Nippon Barrier Free across Japan and 18 countries.
- Plan Do See (青山グランドホテル)minorCulinary collaboration with Chef Shuta Mori to develop and sensory-evaluate cell-cultured duck liver-derived cell-based foie gras dishes. Sensory evaluation meeting held at Aoyama Grand Hotel, Tokyo.
- Atlantis Bioscience (Singapore)minorExclusive one-year distribution agreement for I-MEM food-grade basal medium in Singapore. First international distribution partnership for Integriculture's products.
- Ichimasa Kamaboko (一正蒲鉾)coreThree-party joint R&D (with Maruha Nichiro) on cell-based surimi. Ichimasa contributes fish processing expertise, formulation knowledge, and expansion to surimi-based commercial products. 'Early-Stage Exploration of Production Technology' phase completed November 2025.
- Maruha Nichiro (マルハニチロ)coreThree-party joint R&D (with Ichimasa Kamaboko) on cell-based surimi. Provides live fish cells, marine protein expertise, and global seafood market access. Joint research ongoing since September 2022.
- CulNet Consortium (15+ member companies)coreOpen innovation platform for cellular agriculture supply chain. Members include: IntegriCulture (founder), Sumitomo Riko, Hamano Products, EBARA Corporation, House Foods Group, JT/TABLEMARK, Nichirei Foods, Nissan Chemical, San-Ei Gen F.F.I., Taiyo Nippon Sanso, Dai-Dan, Yamato Seikan, Nakalai Tesque, UBE, A Laboratories, and others. 10+ patent applications filed collectively.
Scale indicators12 records
Recent moves6 records
Expansion highlights8 records
Integriculture competitors and assessment
Company assessmentDirect peers
- SuperMeat: Israeli cultivated chicken company. Direct peer in cellular agriculture for poultry, focused on serum-free culture media - a similar technology priority to Integriculture's serum-free CulNet platform.
- Aleph Farms: Israeli cultivated meat company producing cell-cultured beef steaks. Direct peer in cellular agriculture; both companies pursue 3D tissue constructs and focus on reducing reliance on FBS through proprietary technology.
- Future Meat Technologies: Israeli cultivated meat company focused on cost reduction through proprietary technology and scaling production. Direct peer in cellular agriculture, comparable to Integriculture on the cost-reduction thesis central to the CulNet platform.
- Eat Just (Good Meat): US-based company whose Good Meat division received the world's first regulatory approval for cultivated meat (Singapore, 2020). Direct peer in cultivated meat with regulatory and commercial lead that Integriculture's Singapore SFA filing will seek to match.
- Upside Foods: US-based cultivated meat pioneer (formerly Memphis Meats) producing cell-cultured chicken, beef, and duck. Most directly comparable to Integriculture as a cultivated meat company pursuing both regulatory approval and consumer-facing products, though with a different production technology.
- Shiok Meats: Singapore-based cultivated seafood company. Direct peer in cellular agriculture for crustaceans and seafood; geographic and technological overlap with Integriculture's Singapore regulatory strategy.
- Mosa Meat: Dutch cultivated beef company that produced the world's first cell-cultured hamburger in 2013. Direct peer in cellular agriculture for food, with a comparable focus on reducing the cost of growth media (a key challenge Integriculture's CulNet also addresses).
- Wildtype: US-based cultivated salmon company. Direct peer in cellular agriculture for seafood applications, comparable to Integriculture's cultivated fish/surimi R&D track.
- Umami Bioworks: Singapore-based cultivated seafood company that is an active Integriculture partner (MoU signed August 2025 for fish cell culture cosmetics). Direct peer in cultivated marine ingredients and cellular agriculture infrastructure in Southeast Asia.
- BlueNalu: US-based cultivated seafood company producing cell-cultured fish products. Comparable to Integriculture's joint R&D with Maruha Nichiro and Ichimasa Kamaboko on cultivated surimi and fish cell culture applications.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
Integriculture social profiles
Digital presenceIntegriculture financial estimates
Financial estimateRevenue estimate
Valuation estimate
Integriculture leadership team
Management profileNumber of profiles
Profiles9 records
Integriculture funding detail
Funding detailFunding overview
Funding rounds4 records
Investors21 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Integriculture M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Integriculture
What does Integriculture do?
Integriculture develops and commercializes the CulNet® System, a biomimetic organ-interaction cell culture platform that enables large-scale, low-cost animal cell culture without exogenous growth factors or fetal bovine serum. Around this core platform, the company offers CRDMO services (PiPELiNE), an open-innovation consortium (CulNet Consortium), a materials/equipment marketplace (Ocatté Base), and commercial products including the CELLAMENT® cosmetics ingredient, I-MEM food-grade basal medium, food-grade reagents (iDisper, iCoater), and production-scale bioreactors (Oxy-thru Cultivator, Product Reactor, Advanced C-CulNet).
Is Integriculture a public or private company?
Integriculture is a private company. It is classified as venture growth investor backed and is currently operating.
When was Integriculture founded?
Integriculture was founded in 2015. It employs 11 to 50 people.
Where is Integriculture based?
Integriculture is headquartered in Tokyo, Japan, in the Asia region.
How does Integriculture make money?
Three revenue lines are on record. Cellular Agriculture Infrastructure (CRDMO Services) is the primary driver. The others are cellular Agriculture Products (Cosmetics & Food Ingredients) and consumables and Equipment Sales (Ocatté Base).
Who are Integriculture's main competitors?
Direct peers on record are SuperMeat, Aleph Farms, Future Meat Technologies, Eat Just (Good Meat), Upside Foods, Shiok Meats, Mosa Meat, Wildtype, Umami Bioworks and BlueNalu.
Does Integriculture have an API?
No public API is recorded for Integriculture.
What industry is Integriculture in?
Integriculture's product category is Cellular Agriculture Infrastructure. Its primary akta.pro industry code is AFANAKAE, Cell Line Development & Banking (Food/AG Cell Lines), with a secondary code of HLAAAJAF, Bioprocess Development & Scale-Up/Scale-Down Platforms (DoE, high-throughput, modeling). Its NAICS code is 311 and its SIC code is 2000.