Create Health Ventures

What Create Health Ventures does

Create Health Ventures (legal entity: Create Health Ventures LLC) is a private, Austin-based venture capital firm focused exclusively on early-stage digital health. The firm states it has invested in or advised more than 80 companies and operates as a hands-on portfolio manager led by two Managing Partners, Emma Cartmell and Amit Aysola. Its stated investment thesis targets B2B software and tech-enabled services that sell into healthcare payers and pharmaceutical companies, with the stated goal of improving care access, patient experience, and health outcomes.

The firm's visible portfolio includes nine named companies spanning maternal health (Flourish Care, the leading doula network), Medicaid care coordination (Pair Team, Watershed Health), financial assistance and enrollment (Advocatia), family caregiving (Carallel), patient-reported outcomes (Folia Health), pharma CMC digitization (QBDVision), clinical trial reimbursement (nmible), and AI-enabled clinical trial operations (OmniScience's 'Vivo' agentic AI platform). Investments span seed and Series A stages, with seed deals concentrated in 2023 and a coordinated Series A cluster in October 2025.

Create Health Ventures earns returns through equity participation in portfolio companies, realized upon exit via M&A or IPO. The firm operates with a founder/operator-led model, supported by an LP base of healthcare executives with prior successful exits who mentor portfolio CEOs. Distribution and deal flow are sourced primarily through direct networking, founder referrals, and industry events rather than inbound marketing channels. No fund size, AUM, management fee, or carried interest terms are publicly disclosed. The firm maintains a secondary office in Chicago alongside its Austin headquarters.

Name

Create Health Ventures

Legal name

Create Health Ventures LLC

Website

https://createhealth.vc

Company type

Private

Operating status

Operating

Headcount range

1–10 employees

Short description

Create Health Ventures is a private, Austin-based venture capital firm investing in early-stage digital health companies, focused on B2B software and tech-enabled services that sell to healthcare payers and pharmaceutical companies, led by Managing Partners Emma Cartmell and Amit Aysola.

Ownership category

akta.pro rank

Product category

Venture Capital

NAICS

Funds, Trusts, and Other Financial Vehicles (525)

SIC

Investment Advice (6282)

akta.pro primary industry

Accelerators & Incubators (Investor-Operated) (FSANAAAM)

Keywords

• Venture capital
• Digital health
• Early-stage investing
• Healthcare startups
• Tech-enabled services

Headquarters

HQ city

Austin

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Others

Revenue model

1. Venture Capital Returns: Create Health Ventures generates returns through equity investments in early-stage digital health companies. Their LP base includes leaders with successful healthcare exits who often mentor portfolio CEOs. Returns are realized through portfolio company exits via M&A or IPO.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels2 records

Core offering

Create Health Ventures is a venture capital firm that invests in and actively manages a portfolio of early-stage digital health companies. The firm provides equity capital, operator mentorship, industry relationships, and hands-on portfolio management to founders and CEOs building B2B software and tech-enabled services that sell into healthcare payers and pharmaceutical companies. To date the firm has invested in or advised more than 80 companies.

Product overview

Create Health Ventures is a venture capital firm that has invested in or advised more than 80 digital health companies. The firm operates as an active portfolio manager with an investment thesis focused on B2B software and tech-enabled services that sell into payers and pharmaceutical companies. Their portfolio spans nine portfolio companies: Carallel (caregiving support platform), Watershed Health (care collaboration), Advocatia (healthcare access/enrollment), OmniScience (clinical trial AI operations), Flourish Care (doula care network), Pair Team (Medicaid patient care coordination), QBDVision (pharma R&D digitization), Folia Health (patient-reported outcomes), and nmible (clinical trial reimbursement). The firm brings industry relationships, experience, and operational knowledge to support founders in early-stage digital health businesses.

Differentiator

Problem solved

Functional benefit

Segments2 records

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Scale indicators1 record

Recent moves5 records

Expansion highlights5 records

Direct peers

• Flare Capital Partners: Early-stage digital health venture firm investing in B2B software and tech-enabled services for payers, providers, and pharma. Closely aligned thesis, stage, and operating model with Create Health Ventures.
• .406 Ventures: Early-stage venture firm investing in healthcare IT, digital health, and tech-enabled services targeting payers, providers, and employers. Comparable stage and B2B digital health thesis to Create Health Ventures.
• Frist Cressey Ventures: Healthcare-exclusive venture firm investing in technology-enabled services and digital health companies serving payers, providers, and pharma. Directly comparable sector focus and check size to Create Health Ventures.
• 7wire Ventures: Digital health-focused venture firm backing early-stage companies that sell into payers, providers, and employers. Highly comparable thesis and stage to Create Health Ventures, with a similarly active operating model.
• Oak HC/FT: Venture and growth equity firm investing exclusively in healthcare and fintech, including digital health companies serving payers and pharma. Comparable vertical specialization, though with growth-stage check sizes larger than Create Health Ventures' typical seed exposure.
• Define Ventures: Early-stage venture firm exclusively focused on digital health, investing in B2B companies selling into payers, providers, and pharma. Closely comparable to Create Health Ventures in vertical focus, stage, and target buyer segments.

Broad incumbents

• General Catalyst: Large multi-stage venture firm with a dedicated health and bio practice investing across payer, provider, and pharma digital health themes. Partial overlap with Create Health Ventures at seed stage, but with substantially greater AUM and stage range.
• Andreessen Horowitz (a16z Bio/Health): Large multi-stage venture firm with a dedicated bio/health fund investing across digital health, payer infrastructure, and pharma tech. Overlaps with Create Health Ventures' vertical but operates at much greater scale and broader stage range.
• Optum Ventures: Corporate venture arm of UnitedHealth Group investing across digital health, including payer and pharma adjacencies. Overlapping investment focus with Create Health Ventures but at significantly larger scale and as part of a strategic CVC platform.

Others

• Watershed Health (as portfolio peer): Portfolio company of Create Health Ventures (care collaboration platform), included to illustrate a peer-of-portfolio rather than direct competitor; comparability is via the firm's investment lens, not direct market overlap.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks5 records

Key highlights5 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments7 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Create Health Ventures