Florence Healthcare

What Florence Healthcare does

Florence Healthcare, founded in 2014 and headquartered in Atlanta, Georgia, operates a cloud-based SaaS clinical trial operations platform that digitizes and connects workflows across research sites, pharmaceutical/biotech sponsors, and contract research organizations (CROs). The platform spans site-facing products (eBinders for electronic investigator site files, free StudyOrganizer, eConsent, and eNcounter enrollment automation) and sponsor/CRO-facing products (SiteLink for document exchange and remote monitoring, eTMF for trial master file management), with workflow integration into CTMS, imaging, and payment systems from partners such as Greenphire, truLab, WCG Clinical, Verily, and Yunu. The platform serves 65,000+ study sites and 600+ sponsors across 90+ countries and processes 10 million monitoring workflows per month, with compliance certifications including FDA 21 CFR Part 11, EU Annex 11, ICH GCP/E6(R3), HIPAA, GDPR, and SOC 2 Type 2.

Florence generates revenue primarily through subscription-based SaaS contracts with pharmaceutical sponsors and CROs for SiteLink and eTMF, while research sites receive eBinders and StudyOrganizer at no cost to drive network adoption. Ancillary revenue comes from the FloPro certification program ($200 per certificate). Distribution combines enterprise direct sales to sponsors/CROs, self-serve free onboarding for research sites, and a new AWS Marketplace listing for SiteLink launched in October 2025. Recent strategic emphasis has shifted to AI, with a proprietary Model Context Protocol (MCP) launched in 2025-2026 that exposes eleven site workflow tools to AI agents from Anthropic, OpenAI, and custom sponsor systems, supported by productized AI features including Site Feasibility AI, Document Intelligence Service, Sponsor Site Navigator, TrialFlo, and Budget Auditor. The company has raised approximately $115 million across multiple funding rounds (Series A through C-1, with Insight Partners leading the $80M Series C in 2021 and $27M C-1 in 2022) and acquired VersaTrial in September 2023 to bolster AI-based clinical trial solutions.

Name

Florence Healthcare

Legal name

Florence Healthcare

Website

https://florencehc.com

Company type

Private

Founded year

2014

Operating status

Operating

Headcount range

251–500 employees

Short description

Florence Healthcare is a cloud-based SaaS clinical trial operations platform founded in 2014 that connects 65,000+ research sites with 600+ pharmaceutical sponsors and CROs across 90+ countries, providing eISF, eTMF, eConsent, remote monitoring, and AI agent workflow tools to decentralize and accelerate clinical trials.

Ownership category

akta.pro rank

Product category

Clinical Trial Software

NAICS

Computer Systems Design and Related Services (54151), Professional, Scientific, and Technical Services (54)

SIC

Services-Health Services (8000)

akta.pro primary industry

Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM)

Keywords

• Clinical trial software
• Site enablement platform
• Electronic trial master file
• Electronic investigator site file
• Clinical trial workflow automation

Headquarters

HQ city

Atlanta

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Infrastructure, Operations

Revenue model

1. SaaS Platform Subscriptions: Subscription-based software platform providing clinical trial workflow automation to sponsors, CROs, and research sites. Sites receive eBinders free of charge, with sponsors and CROs paying for platform access and SiteLink/eTMF solutions.
2. Professional Services & Training: FloPro certification program offering professional training and certifications for Florence products at $200 per certificate.

Pricing tiers

Go-to-market motion3 records

Distribution channels3 records

Marketing channels9 records

Core offering

Florence Healthcare operates a cloud-based SaaS clinical trial site enablement platform that connects 65,000+ research sites with 600+ pharmaceutical sponsors and CROs across 90+ countries. Its core offerings include eBinders (electronic Investigator Site File), SiteLink (document exchange and remote monitoring), eTMF (electronic Trial Master File), eConsent, StudyOrganizer, eNcounter (enrollment automation), and ParticipantLink, supported by AI-powered workflow automation and document intelligence.

Product overview

Florence Healthcare offers the Florence Trial Operations Platform, a unified site enablement platform connecting research sites, sponsors, and CROs across 65,000 sites and 600+ sponsors in 90+ countries. The platform consists of site-facing products (eBinders for electronic investigator site files, StudyOrganizer for free study management, eConsent for electronic consent, and eNcounter for enrollment automation), sponsor/CRO-facing products (SiteLink for document exchange and remote monitoring, eTMF for trial master file management, and ParticipantLink for candidate database), and AI-powered add-on modules (Site Feasibility AI, Document Intelligence Service, Sponsor Site Navigator, TrialFlo, and Budget Auditor). The platform enables up to 70% faster study startup and reports $141 million in annual cost savings through workflow automation.

Differentiator

Problem solved

Functional benefit

Brands

• Florence Trial Operations Platform: The company's integrated platform for clinical trial document management, remote monitoring, and site-sponsor connectivity.
• FlorenceCare
• Research Revolution
• The League
• FloPro

Products and services

• Florence Trial Operations Platform Unified cloud-based site enablement platform connecting 65,000+ research sites with 600+ sponsors and CROs across 90+ countries, providing shared workflows for clinical trial operations.
• eBinders Electronic Investigator Site File (eISF) solution that digitizes investigator site files and participant binders for research sites, providing structured regulatory workflows and remote monitoring capabilities for sponsors and CROs. Provided at no cost to research sites.
• SiteLink Document exchange and remote monitoring platform enabling sponsors and CROs to distribute, monitor, and exchange study documents with research sites. Supports 7.2 million monitoring workflows per month across sites in 70+ countries.
• eTMF Electronic Trial Master File solution built for ease-of-use with direct connectivity to study sites for eISF document exchange. Syncs documents directly into the eTMF and enables remote monitoring.
• eConsent Electronic informed consent solution enabling digital participant consenting workflows for clinical trials, supporting both in-person and remote consenting with full compliance and audit trails.
• StudyOrganizer Free study information and password manager that centralizes study bookmarks, passwords, and contacts for busy research sites. Connects with CTMS and other systems to streamline study profile creation.
• eNcounter Enrollment automation solution that centralizes, automates, and optimizes every participant journey from recruitment through follow-up.
• ParticipantLink StudyReady database solution that maintains a repository of study candidates to match with future studies and route directly to research sites.
• FloPro Certification Program Professional training and certification program for Florence product users. Offers certificates for eBinders, eConsent, and other products at $200 per certificate, valid for 2 years.
• Document Intelligence Service AI-powered workflow-aware document quality, classification, and analysis service embedded inside eBinders and eISF that surfaces document issues for human review before they become inspection findings.

Quantifiable outcome

• 70% faster study startup timelines
• +8 more outcomes

Named customers14 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration14 records

AI capability9 records

Feature10 records

Partnerships

Two partnerships are on record, tiered core.

• VersaTrialcoreTechnology or Integration · 25 September 2023Florence Healthcare acquired VersaTrial in September 2023 to enhance its Site Enablement Platform. VersaTrial's clinical trial solutions provider capabilities expanded services for research sites, sponsors, and CROs, improving efficiency, speed, and communication in clinical research operations globally. The acquisition united two eClinical space leaders.
• ScienceMediacoreStrategic or Co-development PartnerPartnership with ScienceMedia to ease training burden for clinical sites. Collaboration aimed at improving site training processes and reducing administrative overhead for research sites using Florence solutions.

Scale indicators16 records

Recent moves6 records

Expansion highlights6 records

Emerging players

• Trial Library: Emerging site feasibility and study planning platform; emerging partial overlap with Florence's Site Feasibility AI module and sponsor-facing workflow tools.

Broad incumbents

• Veeva Systems: Public, enterprise-grade clinical trial platform with Vault CTMS, Vault eTMF, Vault eDMS, and ePRO. Direct overlap with Florence's eTMF, eISF, and eConsent modules, but Veeva sells a much broader commercial and R&D suite to large pharma.
• Medidata (Dassault Systèmes): Industry-standard eClinical suite (Rave EDC, Rave CTMS, eTMF, eCOA) used by most large pharma. Competes with Florence in eTMF and site-facing workflows but is integrated into a much larger Dassault 3DEXPERIENCE portfolio.
• Oracle Clinical One: Oracle's unified clinical trial platform covering EDC, RTSM, eTMF, and ePRO. Competes head-on with Florence for enterprise sponsor RFPs and benefits from Oracle's enterprise cloud and data footprint.
• Signant Health: Specialty eCOA/ePRO, eConsent, and patient engagement vendor for clinical trials. Overlaps with Florence's eConsent and patient-facing data modules and competes for the same sponsor eCOA budget line.

Direct peers

• Advarra: Provider of research site services including IRB review, eRegulatory/eISF (via Longboat), and site training/workflow technology. Direct overlap with Florence's eBinders and site enablement offerings, with similar research-site-first GTM.
• Castor: Cloud EDC and ePRO platform with decentralized trial capabilities; targets sponsors and CROs with a modern, lower-cost alternative to Veeva/Medidata. Comparable in product philosophy (ease of use, sponsor/CRO workflows) and buyer.
• RealTime Software Solutions: Site-focused CTMS, eRegulatory, and eISF vendor for research sites and site networks. Competes directly with Florence's eBinders and eRegulatory offerings on the same SMB/mid-market site buyer.
• Greenphire: Clinical trial financial management and site payment platform; existing Florence integration partner. Adjacent in workflow (financial vs. document), but serves the same sponsor/CRO buyer and the same site workflows.
• Calyx: Provider of EDC, eCOA, IRT, RTSM, and eTMF solutions; repositioned as an AI-native eClinical platform. Closest direct competitor in target buyer (pharma/CRO) and adjacent product coverage (EDC, eTMF, eCOA).

Market position

Strengths4 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/FlorenceHCare
• Facebookfacebook.com/TheFlorenceTeam
• LinkedInlinkedin.com/company/florence-healthcare

Compliance6 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Subsidiaries1 record

Funding overview

Funding rounds5 records

Investors10 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Florence Healthcare