Mevion Medical Systems
Mevion Medical Systems develops and manufactures compact proton therapy systems for cancer treatment, anchored by the MEVION S250 Series. The flagship MEVION S250-FIT is the first proton therapy system designed to fit inside a standard LINAC vault, sold to hospitals and cancer centers globally.
- Company typePrivate
- Founded2004
- HeadquartersLittleton, United States
- Headcount101–250
- GTM typeB2B
- OfferingHardware or Manufacturing
What Mevion Medical Systems does
Mevion Medical Systems, Inc. is a privately-held medical device company founded in 2004 and headquartered in Littleton, Massachusetts, that develops and manufactures compact proton therapy systems for cancer treatment. Its core product platform is the MEVION S250 Series, built around a proprietary 250 MeV TriNiobium Superconducting Cyclotron and including the original MEVION S250, the gantry-based MEVION S250i with HYPERSCAN pencil beam scanning and Adaptive Aperture proton multi-leaf collimator, the multi-room MEVION S250mx, and the flagship MEVION S250-FIT — the first and only proton therapy system designed to fit inside a standard radiation therapy (LINAC) vault, paired with Leo Cancer Care's Marie® upright patient positioning platform. The systems are sold as large one-time capital purchases (e.g., $33 million for the Stanford S250-FIT) bundled with one year of service and maintenance, followed by optional multi-year service contracts at >95% guaranteed uptime; revenue is supplemented by training, implementation, and tailored financing programs. Mevion goes to market through direct enterprise sales, regional offices in EMEA (Maastricht), Asia-Pacific (Tokyo), and China (Kunshan), and channel partners such as TD Tech in Vietnam and Morveducci in Italy, targeting NCI-designated Comprehensive Cancer Centers, academic medical centers, community hospitals, and international first-in-country sites — claiming to equip 50% of leading U.S. cancer centers and capture 60% of the announced U.S. proton therapy market over the past five years.
Mevion Medical Systems firmographics
Firmographics- Name
- Mevion Medical Systems
- Legal name
- Mevion Medical Systems, Inc.
- Website
- https://mevion.com
- Company type
- Private
- Founded year
- 2004
- Operating status
- Operating
- Headcount range
- 101–250 employees
- Short description
- Mevion Medical Systems develops and manufactures compact proton therapy systems for cancer treatment, anchored by the MEVION S250 Series. The flagship MEVION S250-FIT is the first proton therapy system designed to fit inside a standard LINAC vault, sold to hospitals and cancer centers globally.
- Ownership category
- akta.pro rank
Mevion Medical Systems industry classification
Industry- Product category
- Proton Therapy Systems
- NAICS
- Irradiation Apparatus Manufacturing (334517), Medical Equipment and Supplies Manufacturing (3391)
- SIC
- Electromedical & Electrotherapeutic Apparatus (3845), Surgical & Medical Instruments & Apparatus (3841)
- akta.pro primary industry
- Radiation Therapy Planning & Simulation Imaging (CT Sim/MR Sim) (HLAHABAH)
- akta.pro secondary industries
- Reactor Instrumentation & Control (I&C) Platforms (Safety/Non-safety, Digital Upgrades) (EUAKADAH), Radiation Oncology (HLAKAFAC)
Keywords
Where Mevion Medical Systems is headquartered
LocationHeadquarters
- HQ city
- Littleton
- HQ country
- United States
- HQ region
- North America
Offices4 records
Markets served
Mevion Medical Systems business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Supply Chain, Personnel, Marketing or Sales, Operations, Infrastructure
Revenue model
- Proton Therapy System Hardware Sales: Large one-time capital equipment sales of the MEVION S250, MEVION S250i, MEVION S250-FIT, and MEVION S250mx systems to hospitals and cancer centers, typically requiring multi-year capital planning (e.g., the $33 million Stanford system). Includes standard 1-year service and maintenance bundled with the price.
- Service and Maintenance Agreements: Recurring post-installation service contracts with on-site engineering, 24/7 beam availability, quarterly preventative maintenance, and 95%+ contractual uptime guarantee. Optional additional coverage with cost dependent on services and term.
- Customized Business and Financing Programs: Tailored financial programs and proforma support for customers, varying by individual customer needs and including assistance with business planning, market analysis, and capital project development.
- Training, Implementation, and Collaboration Services: Comprehensive training programs for physicians, therapists, dosimetrists, physicists, administrators, and hospital engineers; ramp-up and continuous improvement consulting; and long-term collaboration services for research partnerships.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Multi-year contract | One-time capital equipment purchase (quote-based) with bundled year-1 service |
| Subscription | Annual | Optional multi-year service and maintenance contract (post-warranty) |
Go-to-market motion3 records
Distribution channels5 records
Marketing channels11 records
Mevion Medical Systems product offering
Product offeringCore offering
Mevion Medical Systems designs, manufactures, and installs compact single-room proton therapy systems for the treatment of cancer. Its MEVION S250 Series portfolio—built around a 250 MeV TriNiobium Superconducting Cyclotron—includes the MEVION S250, S250i, S250mx, and S250-FIT systems, which deliver Intensity-Modulated Proton Therapy (IMPT) to hospitals and cancer centers with a fraction of the footprint, cost, and energy of traditional multi-room proton facilities.
Product overview
Mevion Medical Systems offers a unified MEVION S250 Series of compact single-room proton therapy systems for cancer care, built on a common TriNiobium Superconducting Cyclotron platform. The portfolio comprises the MEVION S250 Proton Therapy System, the flagship MEVION S250i with HYPERSCAN and Adaptive Aperture, the MEVION S250mx Multi-Room Proton Therapy System, and the newest MEVION S250-FIT designed to fit into an existing LINAC vault. The S250i and S250-FIT share the HYPERSCAN pencil beam scanning platform for Intensity Modulated Proton Therapy (IMPT) and are designed to support DirectARC proton arc therapy, daily online adaptive proton therapy, and FLASH research capabilities. The S250-FIT is the first and only proton therapy system designed for installation in a standard radiation therapy vault, dramatically reducing infrastructure costs and complexity.
Differentiator
Problem solved
Functional benefit
Brands
- MEVION S250 Series: The overarching product family of compact proton therapy systems, encompassing the S250, S250i, S250-FIT, and S250mx models.
- MEVION S250
- MEVION S250i
- MEVION S250-FIT
- MEVION S250mx
- HYPERSCAN
- Adaptive Aperture
Products and services
- MEVION S250-FIT Proton Therapy System The first and only full proton therapy system designed to fit inside an existing standard LINAC vault (as small as ~110 m² / 1,200 sq ft), featuring HYPERSCAN Pencil Beam Scanning for IMPT, large-bore diagnostic CT at isocenter for IGRT and adaptive therapy, AI-driven treatment planning, and FLASH research readiness. Targets hospitals seeking to add proton therapy without building dedicated proton bunkers.
- MEVION S250i Proton Therapy System Gantry-based compact proton therapy system with a 190-degree rotating gantry and gantry-mounted proton accelerator, integrating HYPERSCAN pencil beam scanning and Adaptive Aperture pMLC for high-quality IMPT treatments at hyper-speed with 1–3 mm collimated spot sizes for 0–32 cm depth range. Used by leading cancer centers for adult and pediatric tumors.
- MEVION S250 Proton Therapy System The world's first compact single-room proton therapy system, utilizing a 250 MeV TriNiobium Superconducting Cyclotron with a Direct Dose beam line design. Pioneered Mevion's compact proton therapy approach with reduced footprint, lower capital costs, and clinical capabilities comparable to conventional LINACs.
- MEVION S250mx Multi-Room Proton Therapy System Mevion's multi-room proton therapy solution that extends the compact single-room architecture to support treatment of multiple rooms in parallel or in series, without disrupting existing clinical services.
- Mevion Service and Maintenance Agreements Recurring post-installation service contracts with on-site engineering, 24/7 beam availability, quarterly preventative maintenance, and 95%+ contractual uptime guarantee. Optional additional coverage with cost dependent on services and term selected.
Quantifiable outcome
- 80% lower capital cost vs. traditional proton therapy systems
- +9 more outcomes
Companies that use Mevion Medical Systems
Customer profileNamed customers16 records
Segments4 records
Ideal customer profiles3 records
Mevion Medical Systems technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration18 records
AI capability4 records
Feature8 records
Mevion Medical Systems partnerships and signals
Strategic signalPartnerships
17 partnerships are on record, tiered flagship — core technology integration for the mevion s250-fit platform, flagship — primary treatment planning and oncology information system partner, supporting — architectural design for the stanford s250-fit installation, supporting — radiation shielding door systems for stanford, core — exclusive distributor for the vietnamese market, flagship — first proton therapy site in vietnam, core — turnkey construction partner for the pascale (naples) project, flagship — first proton therapy center in southern italy, flagship — first s250-fit clinical site and clinical validation partner, supporting — construction and shielding partners for nebraska medicine fit integration, core — industry association partner, core — particle therapy cooperative group partner, core — flagship industry society partner, core — medical physics professional society partner, core — european radiation oncology society partner, core — research and clinical collaboration partner (patient registry) and supporting — multi-vendor clinical interoperability ecosystem.
- Leo Cancer Careflagship — core technology integration for the mevion s250-fit platformLeo Cancer Care's Marie® upright patient positioning and integrated diagnostic CT imaging system is paired with the MEVION S250-FIT, enabling 360-degree patient rotation and removing the need for a rotating gantry. The Marie® platform is central to the FIT architecture and is co-deployed with Mevion at Stanford, Pascale, Tam Anh, and other FIT sites.
- RaySearch Laboratoriesflagship — primary treatment planning and oncology information system partnerRaySearch provides the RayStation® treatment planning system (with HYPERSCAN, Adaptive Aperture, DirectARC, and multi-criteria optimization) and the RayCare® oncology information system. RayStation powers the S250-FIT systems at Stanford, Tam Anh, and Pascale. Some proprietary features of HYPERSCAN with Adaptive Aperture are only available on RayStation.
- Stantecsupporting — architectural design for the stanford s250-fit installationStantec provided architectural design for the Stanford Medicine Cancer Center S250-FIT installation, supporting the fit-out of a conventional 110 m² (1,200 sq ft) LINAC vault into a proton therapy vault.
- NELCOsupporting — radiation shielding door systems for stanfordNELCO provided radiation shielding door systems for the Stanford Medicine Cancer Center S250-FIT installation.
- TD Tech Company (Toan Dien Medical Technology Company Limited)core — exclusive distributor for the vietnamese marketTD Tech Company is Mevion's distributor in Vietnam with more than twenty years of experience in radiation oncology. TD Tech facilitated the Tam Anh General Hospital agreement to bring the first proton therapy system to Vietnam.
- Tam Anh General Hospital Groupflagship — first proton therapy site in vietnamTam Anh General Hospital Group signed a definitive purchase agreement for the MEVION S250-FIT, bringing the first proton therapy system to Vietnam at its new Phu My Hung facility, expected operational by late 2027. One of Vietnam's leading private healthcare systems.
- Morveduccicore — turnkey construction partner for the pascale (naples) projectMorveducci serves as the general contractor responsible for the design and construction of the new proton therapy center at Istituto Nazionale Tumori IRCCS Fondazione G. Pascale in Naples, Italy. Delivered as a turnkey collaboration with Mevion and Leo Cancer Care.
- Istituto Nazionale Tumori IRCCS Fondazione G. Pascaleflagship — first proton therapy center in southern italySelected the MEVION S250-FIT through a competitive European tender to establish the first proton therapy center in Southern Italy. Turnkey project delivered with Leo Cancer Care and Morveducci.
- Stanford Medicine Cancer Center (Stanford Health Care)flagship — first s250-fit clinical site and clinical validation partnerStanford Health Care is the world's first installation of the MEVION S250-FIT inside a conventional LINAC vault (Palo Alto), and the site of the world's first clinical proton therapy treatment on the S250-FIT (June 4, 2026). Deep clinical collaboration with Mevion.
- H&H Design-Build and Kiewitsupporting — construction and shielding partners for nebraska medicine fit integrationH&H Design-Build and Kiewit partnered with Nebraska Medicine to integrate the MEVION S250-FIT into the Fred & Pamela Buffett Cancer Center, providing engineering, construction, and shielding expertise.
- National Association for Proton Therapy (NAPT)core — industry association partnerMevion is a partner of NAPT and is a presenting industry partner at the 2026 National Proton Conference. NAPT advances advocacy, education, and access to proton therapy.
- PTCOG / PTCOG-NAcore — particle therapy cooperative group partnerMevion is a partner of the Particle Therapy Cooperative Group (PTCOG) and PTCOG-NA, supporting research, education, and clinical collaboration in particle therapy.
- ASTRO (American Society for Radiation Oncology)core — flagship industry society partnerMevion is a partner of ASTRO and exhibits annually at the ASTRO Annual Meeting (Booth 1917 in 2024, Booth 1215 in 2025), hosting symposia and product launches.
- AAPM (American Association of Physicists in Medicine)core — medical physics professional society partnerMevion is a partner of AAPM, supporting medical physics research, education, and standards in radiation oncology.
- ESTRO (European Society for Radiotherapy & Oncology)core — european radiation oncology society partnerMevion is a partner of ESTRO and exhibits at the ESTRO Annual Congress (Booth C08:89 in 2026) to introduce the MEVION S250-FIT to the European radiation oncology community.
- Washington University / Siteman Cancer Centercore — research and clinical collaboration partner (patient registry)Washington University developed a multi-center proton patient registry and clinical education programs for Mevion customers to collect clinical data and patient treatment plans and track outcomes. The Siteman Cancer Center at Washington University School of Medicine was also the first to treat a patient on a Mevion S250 in 2013.
- VisionRT, humediQ, C-RAD, Philips, Varian, Elekta, Qfix, Siemens, Airo, BodyTom (3rd party clinical system vendors)supporting — multi-vendor clinical interoperability ecosystemMevion integrates with leading 3rd party clinical systems including RaySearch RayStation/Philips Pinnacle/Varian Eclipse/Elekta XiO for treatment planning; RaySearch RayCare/Varian ARIA/Elekta MOSAIQ OIS; VisionRT AlignRT & GateRT, humediQ Identify, C-RAD Catalyst for motion management; Airo, BodyTom, Siemens CTVision for CT imaging; Qfix kVue, BoS Insert, BoS Headframe for immobilization.
Scale indicators10 records
Recent moves7 records
Expansion highlights5 records
Mevion Medical Systems competitors and assessment
Company assessmentDirect peers
- IBA Worldwide: Global market leader in proton therapy with the ProteusONE single-room and ProteusPLUS multi-room systems. Directly competes with Mevion's MEVION S250 Series for hospital and cancer center proton therapy procurements worldwide.
- Hitachi (Hitachi High-Tech / proton therapy business): Historically a direct proton therapy competitor (PROBEAT systems in Japan and the U.S.). The Hitachi proton therapy business has been reorganized but represents the legacy multi-room proton therapy architecture Mevion's compact S250 Series competes against.
Broad incumbents
- Varian Medical Systems (a Siemens Healthineers company): Largest radiation oncology incumbent offering the ProBeam proton therapy system alongside conventional LINACs and software. Overlaps with Mevion's customer base (cancer centers) and competes across the broader radiation oncology procurement budget.
- Elekta: Major radiation therapy and radiosurgery incumbent offering LINACs (Versa HD, Elekta Unity MR-LINAC) and the Leksell Gamma Knife. Competes with Mevion for hospital radiation oncology capital budgets and through its MOSAIQ OIS integrated into many proton centers.
- Accuray: Radiation oncology equipment maker (CyberKnife, TomoTherapy, Radixact) competing with Mevion for the same hospital capex pool, particularly at community cancer centers evaluating alternatives to proton therapy.
Emerging players
- RaySearch Laboratories: Independent treatment planning (RayStation) and oncology information system (RayCare) vendor. Key Mevion partner whose TPS powers HYPERSCAN/Adaptive Aperture/DirectARC workflows, but also a standalone vendor selling into other proton and photon therapy centers.
- Leo Cancer Care: Developer of the Marie® upright patient positioning platform that is co-deployed with Mevion's S250-FIT to enable vault-compatible proton therapy. A technology partner but with overlapping commercial activity in the upright proton therapy category.
- B dot Medical: Japanese startup developing a compact proton therapy system targeting similar single-room, lower-cost positioning to Mevion. Represents the next wave of compact proton competitors in Asia.
- TAE Life Sciences: Developer of accelerator-based boron neutron capture therapy (BNCT) systems for cancer treatment. Adjacent technology category competing for advanced radiation therapy hospital capex.
- ProNova Solutions: Compact proton therapy system developer (SC360) historically targeting the same single-room, lower-cost segment as Mevion. A relevant emerging peer in the compact proton therapy category despite its different commercial trajectory.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
Mevion Medical Systems social profiles
Digital presenceMevion Medical Systems compliance and trust
Trust signalCompliance7 records
Mevion Medical Systems financial estimates
Financial estimateRevenue estimate
Valuation estimate
Mevion Medical Systems leadership team
Management profileNumber of profiles
Profiles7 records
Mevion Medical Systems subsidiaries and ownership
Company hierarchySubsidiaries4 records
Mevion Medical Systems funding detail
Funding detailFunding overview
Funding rounds12 records
Investors8 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Mevion Medical Systems M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Mevion Medical Systems
What does Mevion Medical Systems do?
Mevion Medical Systems designs, manufactures, and installs compact single-room proton therapy systems for the treatment of cancer. Its MEVION S250 Series portfolio—built around a 250 MeV TriNiobium Superconducting Cyclotron—includes the MEVION S250, S250i, S250mx, and S250-FIT systems, which deliver Intensity-Modulated Proton Therapy (IMPT) to hospitals and cancer centers with a fraction of the footprint, cost, and energy of traditional multi-room proton facilities.
Is Mevion Medical Systems a public or private company?
Mevion Medical Systems is a private company. It is classified as venture growth investor backed and is currently operating.
When was Mevion Medical Systems founded?
Mevion Medical Systems was founded in 2004. It employs 101 to 250 people.
Where is Mevion Medical Systems based?
Mevion Medical Systems is headquartered in Littleton, United States, in the North America region.
How does Mevion Medical Systems make money?
Four revenue lines are on record. Proton Therapy System Hardware Sales are the primary driver. The others are service and Maintenance Agreements, customized Business and Financing Programs and training, Implementation, and Collaboration Services.
Who are Mevion Medical Systems's main competitors?
Direct peers on record are IBA Worldwide and Hitachi (Hitachi High-Tech / proton therapy business). Broad incumbents are Varian Medical Systems (a Siemens Healthineers company), Elekta and Accuray. Emerging players are RaySearch Laboratories, Leo Cancer Care, B dot Medical, TAE Life Sciences and ProNova Solutions.
Does Mevion Medical Systems have an API?
No public API is recorded for Mevion Medical Systems.
What industry is Mevion Medical Systems in?
Mevion Medical Systems's product category is Proton Therapy Systems. Its primary akta.pro industry code is HLAHABAH, Radiation Therapy Planning & Simulation Imaging (CT Sim/MR Sim), with a secondary code of EUAKADAH, Reactor Instrumentation & Control (I&C) Platforms (Safety/Non-safety, Digital Upgrades). Its NAICS code is 334517 and its SIC code is 3845.