Leo Cancer Care

What Leo Cancer Care does

Leo Cancer Care Ltd. is a UK private medical device company (founded in Australia in 2013/2016, re-debuted as Leo Cancer Care in 2021) that develops upright radiotherapy platforms centered on two proprietary technology pillars: a six-degrees-of-freedom upright patient positioning system with 360° rotation (±1 mm isocenter accuracy) and an integrated upright high-rotation fan-beam CT scanner. These are combined in the flagship Marie® upright particle therapy system, which is positioned in front of any fixed radiation beam (proton, carbon ion, neutron, BNCT, FLASH) to eliminate the multi-story, +100-ton rotating gantry used in conventional proton therapy, reducing facility footprint by more than 90% (from ~29,000 sq ft to ~1,700 sq ft) and enabling installation inside an existing LINAC vault.

The product portfolio spans Marie® (FDA 510(k) cleared 2025, CE marked May 2026), the co-developed MEVION S250-FIT™ compact proton therapy system with Mevion Medical Systems, the Eve® static upright positioning system (FDA 510(k) cleared 2024), the Aida upright simulation solution (launched February 2026), and the Grace™ upright photon therapy system (in development). Supporting tools include the StatueQuest pediatric engagement game and the Stanford-licensed AVATAR audio-visual distraction system.

Leo Cancer Care sells multi-million-dollar capital equipment via a direct enterprise field-sales motion supplemented by channel partners (Fosun Pharmaceutical for China) and technology integrators (Mevion, Hitachi, Theryq, Aviko, Neutron Therapeutics, RaySearch), with installation, training, field service, and licensing of co-developed IP as adjacent revenue streams. Customers are hospitals, academic medical centers, and proton/particle therapy centers (McLaren, UW Health, Stanford Medicine, Centre Léon Bérard, CNAO, Istituto Pascale, Atlantic Health Morristown, UNC, Gunma University). The company has raised approximately $65M+ across disclosed rounds (a 2021 Series B of $25.3M, a 2024 Series C with strategic partners, and a 2025 Catalio-led round of $40M plus $20M credit facility) and employs 11-50 staff across Crawley, UK and Middleton, WI.

Name

Leo Cancer Care

Legal name

Leo Cancer Care Ltd.

Website

https://www.leocancercare.com

Company type

Private

Founded year

2016

Operating status

Operating

Headcount range

11–50 employees

Short description

Leo Cancer Care develops beam-agnostic upright radiotherapy platforms — most notably the Marie® upright particle therapy system with integrated upright CT — that replace conventional multi-ton rotating gantries, enabling hospitals and proton therapy centers to deliver upright proton and photon therapy inside existing LINAC vaults.

Ownership category

akta.pro rank

Product category

Radiation Therapy Equipment

NAICS

Irradiation Apparatus Manufacturing (334517), Diagnostic Imaging Centers (621512)

SIC

Surgical & Medical Instruments & Apparatus (3841), X-Ray Apparatus & Tubes & Related Irradiation Apparatus (3844)

akta.pro primary industry

Interventional Radiology & Image-Guided Therapy Systems (HLAHABAG)

akta.pro secondary industry

Radiation Oncology (HLAKAFAC)

Keywords

• Upright radiotherapy systems
• Proton therapy equipment
• Patient positioning systems
• Particle therapy platforms
• Radiotherapy imaging solutions

Headquarters

HQ city

Harley

HQ country

United Kingdom

HQ region

Europe

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Supply Chain, Marketing or Sales, Operations

Revenue model

1. Capital Equipment Sales (Particle Therapy Systems): Multi-million-dollar one-time sales of the Marie® upright particle therapy platform and its integrated upright CT, typically sold to hospital systems, proton therapy centers, and academic medical centers (e.g., installations at McLaren, UW Health, Stanford, CNAO, Istituto Pascale).
2. Capital Equipment Sales (Photon Therapy and Simulation Systems): Future revenue from Grace™ upright photon therapy system (in development) and Aida/Eve upright simulation solutions, plus geographic expansion via channel partners (e.g., Fosun in China).
3. Installation, Training, and Field Service: Professional services including site installation, commissioning, clinical training, and field service (Field Service Engineer roles advertised in the US and remote), supporting deployment and ongoing uptime.
4. Licensing of Audio-Visual and Immobilization IP: Licensing arrangements with co-development partners (e.g., licensing Stanford Medicine's AVATAR audio-visual system, and Orfit upright immobilization prototypes), generating potential royalty/licensing income.

Pricing tiers

Go-to-market motion4 records

Distribution channels5 records

Marketing channels9 records

Core offering

Leo Cancer Care designs and manufactures upright radiotherapy systems, with the Marie® flagship combining a six-degrees-of-freedom upright patient positioning system (with 360° rotation) and an integrated upright fan-beam CT scanner into a beam-agnostic platform that sits in front of any fixed particle or photon beam to enable gantry-less proton, carbon ion, neutron, and FLASH therapy inside a standard LINAC vault. The portfolio extends to the co-developed MEVION S250-FIT™ compact proton therapy system (with Mevion Medical Systems, powered by RayStation), the Eve® static upright patient positioning system, the Aida upright simulation solution, and the future Grace™ upright photon therapy system, sold to hospitals, academic medical centers, and proton therapy centers as enterprise capital equipment.

Product overview

Leo Cancer Care offers an integrated platform of upright radiotherapy solutions built around two shared technology pillars — a six-degrees-of-freedom upright patient positioning system and an upright fan-beam CT scanner — that together support the full clinical workflow from simulation through to treatment. The core particle-therapy product is Marie®, a beam-agnostic upright particle therapy platform that integrates with the Mevion S250-FIT™ Proton Therapy System (co-developed with Mevion Medical Systems and powered by RayStation) to deliver a combined compact proton solution. Grace™ is the company's future upright photon-therapy system (in development, combining the upright CT with a 6MV fixed-beam linac and ultra-fast MLC). Outside the treatment room, the Eve® static upright patient positioning system supports setup training and immobilization (FDA 510(k) cleared 2024), and Aida adds a dedicated upright CT scanner for simulation rooms to free up treatment-room time. Supporting pediatric tools include the StatueQuest interactive game and the Stanford-licensed AVATAR audio-visual system.

Differentiator

Problem solved

Functional benefit

Brands

• Marie®: Leo Cancer Care's flagship upright particle therapy solution, combining an upright patient positioning system with an upright fan-beam CT scanner; named after Nobel prize winner Marie Curie. FDA 510(k) cleared in 2025 and CE marked in May 2026.
• Eve®
• Aida
• Grace™
• MEVION S250-FIT™
• StatueQuest

Products and services

• Marie® Upright Particle Therapy System Beam-agnostic upright particle therapy platform combining a six-degrees-of-freedom (±1 mm isocenter accuracy, 360° rotation) upright patient positioning system with an integrated upright fan-beam CT scanner; positioned in front of any fixed proton, carbon ion, neutron, BNCT, or FLASH beam to enable gantry-less particle therapy inside a standard LINAC vault. Sold to hospitals, academic medical centers, and proton therapy centers.
• MEVION S250-FIT™ Proton Therapy System (with Mevion Medical Systems) Ultra-compact proton therapy system co-developed with Mevion Medical Systems, combining the world's smallest proton accelerator with Leo Cancer Care's Marie® upright positioning and CT imaging to provide complete 360-degree beam access proton therapy inside a LINAC vault; features HYPERSCAN pencil beam scanning with Adaptive Aperture pMLC and SmartARC delivery powered by RayStation.
• Eve® Static Upright Patient Positioning System Static upright patient positioning system used outside the treatment room to optimize setup posture, create custom immobilization, train staff, and prepare patients without disrupting clinical operations. Does not require an x-ray shielded room. Sold to radiotherapy departments and simulation suites.
• Aida Upright Simulation Solution Upright simulation solution pairing the Eve® static positioning system with Leo Cancer Care's dedicated upright fan-beam CT scanner in a separate simulation room to enable treatment planning-quality upright CT and increase patient throughput (84 cm bore, 62.3 cm FOV, 80/140 kV, ±5/10/15° gantry tilt, 160 cm travel, 1–4 mm slices, 32 rows).
• Grace™ Upright Photon Therapy System Upright photon therapy system under development, integrating an upright fan-beam CT at the treatment isocenter with a 6MV fixed-beam linear accelerator and an ultra-fast multi-leaf collimator for simulation, replanning, and treatment in a single room. Targets the ~8,000 photon facilities globally that the company identifies as addressable market.

Quantifiable outcome

• More than 90% reduction in space required for proton therapy (from over 29,000 sq ft to approximately 1,700 sq ft)
• +7 more outcomes

Named customers9 records

Segments6 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration7 records

Feature7 records

Partnerships

20 partnerships are on record, tiered minor, core and flagship.

• MorveducciminorImplementation/ SI/ Consulting Partner · 17 May 2026Italian consulting/implementation partner collaborating with Mevion and Leo Cancer Care on the Istituto Pascale MEVION S250-FIT turnkey project in Naples, the first proton therapy center in Southern Italy.
• OrfitminorStrategic or Co-development Partner · 1 January 2026Co-developed innovative upright immobilization prototypes unveiled at ESTRO 2026, supporting the upright radiotherapy workflow.
• Fosun PharmaceuticalcoreChannel Partner/ Reseller/ Distributor · 6 November 2025Distribution agreement to bring the Marie® particle therapy system to mainland China following FDA regulatory clearance, as part of Fosun's push to deliver advanced cancer care in the Chinese market.
• Triple Ring TechnologiesminorStrategic or Co-development Partner · 14 October 2025Collaboration (with Malcova and Leo Cancer Care) on patient-first breast imaging and upright radiation therapy systems, aimed at improving early detection accuracy and treatment precision while reducing patient discomfort.
• MalcovaminorStrategic or Co-development Partner · 14 October 2025Collaboration with Triple Ring and Leo Cancer Care on patient-focused breast imaging and upright radiation therapy innovations.
• Stanford MedicineflagshipStrategic or Co-development Partner · 1 January 2025First site to install and treat with the integrated Marie + Mevion S250-FIT system, completing the world's first compact upright proton therapy treatment on a pediatric patient on 4 June 2026. Stanford's AVATAR audio-visual system was licensed to Leo Cancer Care for pediatric upright radiotherapy.
• Macmillan Cancer SupportminorStrategic or Co-development Partner · 11 June 2024Listed as a Series C strategic partner alongside McLaren Healthcare Corporation, Cone Health, WARF, Aviko Radiopharmaceuticals, and EDBI to advance the upright radiation therapy system.
• TibaRay Inc.coreStrategic or Co-development Partner · 1 June 2024Co-development agreement announced June 2024 to develop an upright linear accelerator combining TibaRay's accelerator technology with Leo Cancer Care's patient positioning and imaging system.
• HitachicoreTechnology or Integration · 1 January 2023Beam-source partner whose fixed particle beam is compatible with Leo Cancer Care's beam-agnostic Marie® platform. Listed in the Particle Therapy partner ecosystem to power particle therapy beams.
• TheryqcoreTechnology or Integration · 1 January 2023Partnership to bring FLASH radiation therapy to the upright Marie® platform, enabling a fixed FLASH beam in front of the upright positioning system.
• Aviko RadiopharmaceuticalscoreTechnology or Integration · 1 January 2023Listed as a Series C strategic partner and ecosystem member for the Marie® particle therapy platform, supporting new treatment modalities in the upright position.
• Neutron TherapeuticscoreTechnology or Integration · 1 January 2023Ecosystem partner for neutron beam therapy integrated with the Marie® upright positioning system, opening the door to additional treatment modalities.
• McLaren Healthcare Corporation / McLaren Proton Therapy CenterflagshipStrategic or Co-development Partner · 1 June 2022Landscape partner and investor: McLaren Proton Therapy Center in Flint, Michigan ordered two Marie® upright units in 2022 (replacing a planned traditional gantry), with installations completed 2023–2024. McLaren's CAO Greg Lane sits on the Leo Cancer Care board. McLaren was named a Series C strategic partner.
• UW Health (Madison, Wisconsin)flagshipStrategic or Co-development Partner · 17 May 2022First institution in the world to sign with Leo Cancer Care (Eastpark Medical Center groundbreaking 17 May 2022). UW Health is installing a Marie® system alongside a traditional gantry room; Marie® installation began February 2024. UW Health also participated in the Series C funding round.
• Mevion Medical SystemsflagshipStrategic or Co-development Partner · 1 January 2022Co-developed the MEVION S250-FIT™ ultra-compact proton therapy system that integrates Mevion's smallest proton accelerator with Leo Cancer Care's Marie® upright patient positioning and CT imaging platform. The combined system is positioned in front of a fixed beam and fits inside an existing LINAC vault. The collaboration enabled the world's first compact upright proton therapy treatment at Stanford Medicine in June 2026 and supports installations at McLaren, UW Health, Atlantic Health Morristown, UNC Health, and Istituto Pascale.
• RaySearch LaboratoriescoreTechnology or Integration · 1 January 2022Treatment planning partner; Leo Cancer Care has partnered with RaySearch Laboratories to integrate upright treatment planning into RayStation / RayCare oncology information system, used in the MEVION S250-FIT (powered by RayStation with Adaptive Aperture® pMLC).
• Centre Léon Bérard (Lyon, France)flagshipStrategic or Co-development Partner · 1 January 2021Long-term research partner and first installation site (2021). Conducted a three-phase research program on upright patient positioning for pelvic radiotherapy, generating peer-reviewed publications and clinical evidence. Collaboration is expanding post-CE mark to include upright CT imaging and positioning using Marie.
• Princess Margaret Cancer CentreminorStrategic or Co-development PartnerNamed as a pediatric upright radiotherapy research collaborator alongside Stanford and Centre Léon Bérard, working to validate and expand pediatric upright treatments.
• Gunma University Heavy Ion Medical Center (Japan)coreStrategic or Co-development PartnerResearch customer using Leo Cancer Care's demonstration upright patient positioning system to lead research on upright positioning reproducibility and new immobilization techniques for heavy ion radiotherapy.
• Royal Philips (PreciseOnco consortium)minorStrategic or Co-development PartnerIndustry ecosystem player cited for €14.9M EU funding of the PreciseOnco consortium in February 2026; relevant industry context for integrated, data-driven cancer care platforms.

Scale indicators10 records

Recent moves9 records

Expansion highlights8 records

Direct peers

• Mevion Medical Systems: Mevion co-develops the integrated S250-FIT proton therapy system with Leo Cancer Care and is the closest direct partner/peer — both companies target compact, vault-friendly proton therapy and share flagship commercial deployments (Stanford, McLaren, Istituto Pascale).
• Ion Beam Applications (IBA): IBA is the world's largest dedicated proton therapy vendor (ProteusONE, ProteusPLUS) and competes head-to-head with Leo's Mevion-integrated offering for new compact proton therapy installations.
• Theryq: Theryq is developing FLASH proton therapy beams and is a named beam-source partner for Leo's Marie platform; together they target upright FLASH therapy as an emerging modality.

Broad incumbents

• Varian Medical Systems (Siemens Healthineers): Varian is the global leader in conventional radiotherapy and proton therapy systems (ProBeam) and competes with Leo's upright positioning concept inside established hospital procurement decisions across photon and particle therapy.
• Elekta: Elekta is a leading global radiotherapy and radiosurgery vendor (Elekta Unity, Versa HD, Gamma Knife) competing for the same hospital CapEx budgets that Leo targets with Marie and future Grace systems.
• Hitachi (Hitachi High-Tech): Hitachi supplies fixed-beam proton therapy systems and is both a named beam-source partner for Leo's beam-agnostic Marie platform and a competitor in the broader particle therapy equipment market (including carbon ion).
• Accuray: Accuray (CyberKnife, TomoTherapy, Radixact) competes with Leo's photon and particle therapy offerings for hospital radiotherapy modernization budgets and addresses similar precision-radiotherapy buyer personas.

Emerging players

• ViewRay: ViewRay pioneered MR-guided radiation therapy (MRIdian) and competes in the advanced radiotherapy capital equipment space that Leo targets with Marie and Grace, with a comparable scale and recent commercial-stage profile.
• ProNova Solutions: ProNova is a compact proton therapy peer targeting smaller footprint, lower-cost proton installations and competing with Leo's Mevion-integrated solution for community cancer centers.

Others

• RaySearch Laboratories: RaySearch provides the treatment planning system (RayStation/RayCare) that powers the Mevion S250-FIT and integrates with Leo's upright positioning; it is an enabling technology partner for Leo's clinical workflow.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat7 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/leo_cancer_care
• YouTubeyoutube.com/channel/UCuQIqksV0Xw78qV0e6Gh1Ag
• Facebookfacebook.com/LeoCancerCare
• LinkedInlinkedin.com/company/leocancercare

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Funding overview

Funding rounds5 records

Investors16 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Leo Cancer Care