cliexa
cliexa is a Denver-based healthcare AI company building an AI-powered clinical intelligence platform that combines a proprietary Clinical Rules Engine with LLM architecture and 12M+ patient data points. It serves health systems, specialty practices, research institutions, life sciences firms, and government health agencies.
- Company typePrivate
- Founded2015
- HeadquartersDenver, United States
- Headcount11–50
- GTM typeB2B
- OfferingSoftware
What cliexa does
cliexa is a Denver-based, privately-held healthcare technology company incorporated in Delaware in 2015 that builds an AI-powered clinical intelligence platform for healthcare providers, payers, life sciences firms, and government health agencies. The platform combines a proprietary Clinical Rules Engine (validated in clinical settings and published in research since 2016) with transformer-based LLM architecture and XGBoost classifiers, trained on 12M+ real patient data points through the Mayo Clinic Platform_Accelerate program. The product surface is organized into twelve branded modules across three functional layers: Aggregate (cliexaTrac patient engagement, cliexaConnect interoperability, cliexaEcho synthetic data), Curate (cliexaProtocols rules engine, cliexaAI core intelligence, cliexaGuidelines decision support), and Deliver (cliexaHub integration hub, cliexaDiagnostics clinician insights, cliexaSense AI Scribe, cliexaARCH billing, cliexaProSkedge surgical scheduling), with bidirectional integration into Epic, Cerner, athenahealth, eClinicalWorks, Healthie, and Greenway EMRs.
The company monetizes primarily through enterprise subscription contracts with per-encounter consumption pricing (charges triggered only when clinicians interact with the cliexa insight panel), supplemented by implementation and professional services that take most clients live within 6-10 weeks. Distribution combines direct enterprise field sales, channel reseller partnerships (SpringParker in the US, Coso, Diginova in the UAE and Saudi Arabia, BDR), and marketplace listings on athenahealth and Microsoft Azure. Customer segments span health systems (Mayo Clinic Platform, Banner Health, MaineHealth, Columbia University Medical Center), specialty practices (Colorado Arthritis Center, Gastro Care Partners, ARpain, Wound Care Associates), research organizations (ACC, University of Colorado Boulder, PIRE), life sciences companies (top-10 global pharma engagement), and government health agencies (US Defense Health Agency, European Social Security Administration). Certifications include SOC 2 Type II, HITRUST r2, HIPAA, and GDPR compliance, with CMS AI guidance alignment added in 2026.
cliexa firmographics
Firmographics- Name
- cliexa
- Legal name
- cliexa Inc.
- Website
- https://cliexa.com
- Company type
- Private
- Founded year
- 2015
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- cliexa is a Denver-based healthcare AI company building an AI-powered clinical intelligence platform that combines a proprietary Clinical Rules Engine with LLM architecture and 12M+ patient data points. It serves health systems, specialty practices, research institutions, life sciences firms, and government health agencies.
- Ownership category
- akta.pro rank
cliexa industry classification
Industry- Product category
- Healthcare AI Clinical Intelligence
- NAICS
- Software Publishers (513210), Software Publishers (5132)
- SIC
- Services-Prepackaged Software (7372)
- akta.pro primary industry
- Software as a Medical Device (SaMD) – Clinical Decision & Diagnostic Software (HLACANAD)
- akta.pro secondary industries
- DTx/SaMD Regulatory, Quality & Compliance Software (QMS/ISO/FDA) (HLACANAN), Clinical CROs (Phase I–IV) (HLAGAAAA), Clinical Data Management, Biostatistics & Statistical Programming CROs (HLAGAAAF)
Keywords
Where cliexa is headquartered
LocationHeadquarters
- HQ city
- Denver
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
cliexa business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure
Revenue model
- AI Platform Subscription: AI solutions ranging from clinical prediction models to full revenue cycle management (RCM) integration. Pricing is use case-dependent, charged per encounter when users interact with the cliexa insight panel.
- Implementation and Professional Services: Implementation, deployment, and training services. Most clients are live within 6-10 weeks with end-to-end deployment handled by cliexa team.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Multi-year contract | Custom enterprise pricing based on use case and scope |
Go-to-market motion3 records
Distribution channels4 records
Marketing channels10 records
cliexa product offering
Product offeringCore offering
cliexa is an AI-powered clinical intelligence platform that delivers AI-driven clinical decision support, documentation, revenue cycle management, and patient engagement tools integrated with major EMR systems. The platform combines a proprietary clinical rules engine with transformer-based LLM architecture to provide real-time risk stratification, AI scribing, denial prevention, and synthetic data generation for healthcare systems, specialty practices, research organizations, and life sciences companies.
Product overview
cliexa is an AI-powered clinical intelligence platform with a platform-plus-modules architecture. At its core is cliexaAI, combining transformer-based LLM architecture with the proprietary cliexaProtocols (Clinical Rules Engine) to deliver true clinical reasoning across the patient journey. The platform operates through three functional layers: Aggregate (cliexaTrac for patient engagement, cliexaEcho for synthetic data generation, cliexaConnect for interoperability), Curate (cliexaProtocols/Clinical Rules Engine for clinical reasoning, cliexaAI for core intelligence, cliexaGuidelines for decision support), and Deliver (cliexaHub as integration hub, cliexaDiagnostics for clinical insights, cliexaSense AI Scribe for documentation, cliexaARCH for billing/revenue cycle, cliexaProSkedge for surgical scheduling). The platform integrates with all major EMR systems (Epic, Cerner, Athenahealth, eClinicalWorks, Healthie, Greenway Health) and major cloud platforms (Microsoft Azure, Google Cloud). Specializations include opioid use disorder risk prediction, chronic disease management, and revenue cycle optimization.
Differentiator
Problem solved
Functional benefit
Brands
- cliexaAI: The core AI intelligence powering the cliexa ecosystem through multi-source learning and clinical reasoning
- cliexaTrac
- cliexaEcho
- cliexaConnect
- cliexaHub
- cliexaDiagnostics
- cliexaGuidelines
- cliexaSense
- cliexaARCH
- cliexaProSkedge
Products and services
- cliexaAI Advanced AI engine powering all cliexa platforms, combining transformer-based large language model architecture with a proprietary clinical rules engine to deliver clinical reasoning across healthcare settings.
- cliexaTrac Patient engagement platform empowering patients with personalized, connected care using real-time data and AI for smart triage, automated engagement, and treatment guidance between visits.
- cliexaEcho Synthetic clinical data generation engine that continuously trains and tests AI models using realistic, deidentified data grounded in true clinical logic for model development and algorithm training.
- cliexaProtocols (Clinical Rules Engine) Proprietary clinical rules engine providing true clinical reasoning with algorithmic fail-safes, validated in clinical settings since 2016. Foundational intelligence layer powering all cliexa microservices with cross-domain comorbidity awareness.
- cliexaGuidelines AI-powered clinical decision support delivering real-time insights with evidence-based recommendations, personalized care pathways, and clinical compliance guidance at the point of care.
- cliexaHub Centralized command center for managing the entire cliexa ecosystem across clinical, operational, and financial workflows. Serves as administrative and analytics backbone with population health dashboards and workflow configuration engine.
- cliexaDiagnostics AI-powered clinical workflow automation providing real-time insights, automated documentation, and clinical decision support embedded directly into electronic medical records.
- cliexaSense (AI Scribe) AI scribe powered by true clinical reasoning that guides documentation in real time during clinical decisions with full awareness of patient context, co-morbidities, workflows, and payer requirements.
- cliexaARCH (Billing Insights) AI-powered revenue cycle management and billing intelligence platform with self-learning optimization. Analyzes, resolves, and ensures compliance for every claim while preventing denials and maximizing reimbursement.
- cliexaProSkedge Automated surgical scheduling platform connecting EHRs, workflows, and patients to eliminate delays, improve OR utilization, and ensure patients are clinically and operationally ready for procedures.
- cliexa-OpiSafe Opioid Stewardship Platform Comprehensive AI-powered platform for opioid stewardship and behavioral health management integrating AI-powered OUD risk prediction with four-tier stratification, opioid tapering management, and treatment referral with care coordination.
- cliexaConnect (Advanced Interoperability) Real-time interoperability enriched with clinical reasoning and standardization. Enables bi-directional EMR connectivity and data exchange across multiple systems including support for HL7, FHIR, CCDA, and SMART on FHIR standards.
- cliexaAI Opioid Use Disorder Solution Containerized clinical decision support model combining XGBoost classifier with real patient records and proprietary Clinical Rules Engine to deliver real-time, interpretable four-tier risk stratification for early identification of patients at risk for opioid use disorder.
Quantifiable outcome
- 80% reduction in documentation time per encounter
- +8 more outcomes
Companies that use cliexa
Customer profileNamed customers17 records
Segments4 records
Ideal customer profiles5 records
cliexa technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration8 records
AI capability9 records
Feature6 records
cliexa partnerships and signals
Strategic signalScale indicators23 records
Recent moves6 records
Expansion highlights6 records
cliexa competitors and assessment
Company assessmentDirect peers
- Augmedix: Ambient medical documentation and AI scribing service for hospitals and specialty practices; closest direct competitor to cliexaSense in the documentation wedge.
- Notable: AI platform for clinical workflows including scribing, prior authorization, and patient intake; overlaps with cliexa across documentation, RCM automation, and clinical workflow optimization.
- Abridge: AI medical scribe and clinical conversation platform serving health systems and specialty practices; directly competes with cliexaSense in ambient documentation and increasingly in clinical decision support.
- Innovaccer: Healthcare data and analytics platform with population health, interoperability, and AI clinical decisioning; comparable to cliexaHub and cliexaConnect across integrated data and workflow layers.
- Suki AI: AI voice assistant and clinical documentation tool for physicians; competes with cliexaSense in AI scribing and with cliexaDiagnostics in clinician workflow automation.
Emerging players
- Qventus: AI for hospital operations including surgical scheduling and discharge planning; overlaps with cliexaProSkedge and cliexaHub in operational automation for health systems.
Broad incumbents
- Olive AI: Healthcare AI automation platform focused on revenue cycle and administrative workflows; competes most directly with cliexaARCH in denial prevention and claims intelligence.
- Health Catalyst: Data and analytics platform for health systems including AI-driven decision support and population health; competes with cliexa in clinical intelligence, analytics, and EMR-agnostic integration.
- Nuance (Microsoft) DAX Copilot: Established ambient clinical intelligence product within Microsoft Dragon portfolio, deeply embedded in Epic and large health systems; competes with cliexaSense and cliexaAI in ambient documentation and decision support.
- LeanTaas: AI-driven scheduling, OR optimization, and patient flow platform for health systems; overlaps with cliexaProSkedge in surgical scheduling and with cliexaHub in operational analytics.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
cliexa social profiles
Digital presencecliexa compliance and trust
Trust signalCompliance4 records
cliexa financial estimates
Financial estimateRevenue estimate
Valuation estimate
cliexa leadership team
Management profileNumber of profiles
Profiles1 record
cliexa funding detail
Funding detailFunding overview
Funding rounds5 records
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
cliexa M&A and investment
M&A and investmentM&A2 records
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about cliexa
What does cliexa do?
cliexa is an AI-powered clinical intelligence platform that delivers AI-driven clinical decision support, documentation, revenue cycle management, and patient engagement tools integrated with major EMR systems. The platform combines a proprietary clinical rules engine with transformer-based LLM architecture to provide real-time risk stratification, AI scribing, denial prevention, and synthetic data generation for healthcare systems, specialty practices, research organizations, and life sciences companies.
Is cliexa a public or private company?
cliexa is a private company. It is classified as venture growth investor backed and is currently operating.
When was cliexa founded?
cliexa was founded in 2015. It employs 11 to 50 people.
Where is cliexa based?
cliexa is headquartered in Denver, United States, in the North America region.
How does cliexa make money?
Two revenue lines are on record. AI Platform Subscription is the primary driver. The others are implementation and Professional Services.
Who are cliexa's main competitors?
Direct peers on record are Augmedix, Notable, Abridge, Innovaccer and Suki AI. Qventus is listed as an emerging player. Broad incumbents are Olive AI, Health Catalyst, Nuance (Microsoft) DAX Copilot and LeanTaas.
Does cliexa have an API?
No public API is recorded for cliexa.
What industry is cliexa in?
cliexa's product category is Healthcare AI Clinical Intelligence. Its primary akta.pro industry code is HLACANAD, Software as a Medical Device (SaMD) – Clinical Decision & Diagnostic Software, with a secondary code of HLACANAN, DTx/SaMD Regulatory, Quality & Compliance Software (QMS/ISO/FDA). Its NAICS code is 513210 and its SIC code is 7372.