PHARMASEAL

What PHARMASEAL does

PHARMASEAL is a Nottingham, UK-based software company that has built and commercializes Engility, a cloud-based SaaS platform combining Clinical Trial Management System (CTMS) and electronic Trial Master File (eTMF) capabilities for the life sciences sector. The product is marketed primarily to biopharmaceutical sponsors, medical device manufacturers, Contract Research Organizations (CROs), and academic research institutions, with secondary use cases in animal health and nutraceuticals. The platform emphasizes unified trial governance across sponsor and supplier ecosystems, rapid implementation measured in weeks rather than months, and a proprietary Continuous Validation methodology that pairs 4,500+ automated tests with same-day validated releases from code freeze to sign-off. Engility Connect extends the system to supply chain collaboration, and Standard and Enterprise pricing tiers are configured per trial rather than per user or site, with add-on services for managed cloud integration, SSO, data migration, and bespoke training.

The company was founded in 2016 by Daljit Cheema, the former CTO of ClinPhone who led it through its 2006 LSE IPO and 2008 acquisition by PAREXEL, and subsequently headed Perceptive Informatics. PHARMASEAL launched Engility CTMS in January 2019 and added integrated eTMF document storage in April 2020, followed by modules for site monitoring, issue management, and dynamic visit forecasting. The go-to-market combines direct enterprise sales (with 'Request a Demo' and custom pricing motions), an active industry events presence (COG CRO Summit, SCOPE, DIA, CDISC TMF Interchange, ACDM, EUCROF), and a channel partner ecosystem of Value Add Resellers, consulting partners (MedSmart LLC, Entec Health Limited), and integration partners (Medrio, Viedoc, Arkivum, Mayet, Ledger Run). As of the input, PHARMASEAL has raised approximately £1.5M-£1.8M cumulatively across seed and early-stage rounds led by Mercia Fund Managers (including the MEIF Proof of Concept & Early Stage Fund) and angel investors, and operates with 11-50 employees serving customers across the UK, EU, US, and APAC.

Name

PHARMASEAL

Legal name

PHARMASEAL

Website

https://pharmaseal.co

Company type

Private

Founded year

2016

Operating status

Operating

Headcount range

11–50 employees

Short description

PHARMASEAL provides Engility, a cloud-based SaaS platform that unifies CTMS and eTMF capabilities for biopharmaceutical sponsors, medical device manufacturers, CROs, and academic institutions. It sells per-trial subscriptions with continuous validation methodology and supply chain collaboration.

Ownership category

akta.pro rank

Product category

Clinical Trial Management Software

NAICS

Software Publishers (5132)

SIC

Services-Prepackaged Software (7372)

akta.pro primary industry

Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM)

Keywords

• Clinical trial management
• Electronic trial master file
• CTMS software
• ETMF solutions
• Clinical trial technology

Headquarters

HQ city

Nottingham

HQ country

United Kingdom

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. SaaS Subscription - Engility Standard: Clinical Trial Management System with regulatory document tracking, priced per month starting at $3K. Includes Admin & Configuration, Study & Contact Management, Monitoring, Site Contracts & Payments, Issue Management, Regulatory Document Tracking, Embedded Business Intelligence, Self-Service & Ad-hoc Reporting.
2. SaaS Subscription - Engility Enterprise: Clinical Trial Management System with fully integrated eTMF document management. Includes all Standard features plus eTMF Document Management capabilities.
3. Add-on Services: Optional add-ons including Managed Cloud Integration Services, Single Sign-On, Data Migration, Bespoke Training, and Enhanced Account Management.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels7 records

Core offering

PHARMASEAL develops and sells the Engility® platform, a unified cloud-based SaaS clinical trial management system that combines Clinical Trial Management System (CTMS) and electronic Trial Master File (eTMF) capabilities. The platform enables biopharmaceutical, medical device, CRO, and academic organizations to manage trial oversight, monitoring, regulatory document tracking, and sponsor-supplier collaboration through a single system with continuous validation methodology and no per-user pricing.

Product overview

PHARMASEAL offers the Engility® unified platform for clinical trial management. The platform consists of three core product modules: Engility® CTMS (Clinical Trial Management System) for trial oversight, monitoring, and regulatory tracking; Engility® eTMF (Electronic Trial Master File) for integrated document management; and Engility® Connect for supply chain collaboration. These modules are available as Standard ($3K/month) or Enterprise tiers, with optional add-ons including managed cloud integration services, SSO, data migration, and bespoke training. The cloud-based SaaS platform emphasizes rapid implementation, no user-based pricing, and standardized EDC integration.

Differentiator

Problem solved

Functional benefit

Products and services

• Engility® Platform Adaptive, cloud-based unified platform enabling smarter management and execution of clinical trials. Integrates CTMS and eTMF capabilities with supply chain collaboration features for sponsors and suppliers, designed for companies of all sizes with single to volume-based trials and no user-based pricing.
• Engility® CTMS Clinical Trial Management System providing trial oversight for study management, monitoring, issue management, site contracts and payments, and regulatory document tracking. Includes embedded business intelligence and self-service reporting for clinical operations professionals managing internal and outsourced clinical trials.
• Engility® eTMF Electronic Trial Master File document management system providing unified document management with integrated CTMS capabilities. Supports compliance tracking, regulatory submission readiness, and agentic TMF capabilities including document auto-classification, autonomous reconciliation, and self-healing metadata correction.
• Engility® Connect Supply chain collaboration module enabling sponsors and suppliers (such as CROs) to share the Engility system for greater efficiency and transparency. Supports better decision-making and reduced risk across the trial supply chain with no additional per-user cost.
• Rapid Implementation Service Professional implementation service delivering faster deployment of the Engility platform within weeks rather than months, with configurable setup based on number of trials rather than users.
• Validation Services

Quantifiable outcome

• Rapid implementation within weeks instead of months
• +2 more outcomes

Named customers20 records

Segments6 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

AI capability5 records

Feature8 records

Partnerships

Seven partnerships are on record, tiered core and minor.

• ArkivumcoreTechnology or Integration · 2 July 2025Integration partnership announced July 2025. Arkivum provides archiving and data management solutions. Partnership enables extended data lifecycle management capabilities within the Engility platform.
• ViedoccoreTechnology or Integration · 1 January 2025Technical integration partnership announced in 2025. Viedoc provides EDC and clinical data management solutions. Partnership enables interoperability between Engility and Viedoc platforms.
• MayetcoreTechnology or Integration · 1 January 2025Strategic integration partnership announced 2025. Mayet provides clinical operations technology. Podcast collaboration featuring Ricky Lakhani and Tom Lazenby from Mayet demonstrates close working relationship.
• Ledger RuncoreTechnology or Integration · 1 October 2024Partnership announced October 2024 to enhance clinical business operations. Ledger Run provides clinical operations technology solutions.
• MedriocoreTechnology or Integration · 30 June 2021Technical integration partnership announced June 2021. Medrio is an EDC (Electronic Data Capture) provider. Partnership enables standardized integration between Engility CTMS and Medrio's EDC platform.
• MedSmart LLCminorImplementation/ SI/ Consulting PartnerFounded 2019 by Dona Occhipinti, specializing in medical device clinical evaluations and post-market clinical follow-up requirements for US and CE-marking registrations. Provides implementation services for Engility platform in medical device sector.
• Entec Health LimitedminorImplementation/ SI/ Consulting PartnerUK-based healthcare market development company supporting medical technology manufacturers with market-entry and commercial partnership. Able to support brand ambition with professional business development services.

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Veeva Systems: Dominant enterprise CTMS and eTMF vendor via the Veeva Vault CTMS and Vault eTMF suites, serving most large global pharma sponsors. It is the most direct competitor to PHARMASEAL's combined CTMS+eTMF offering, though it competes at significantly larger customer scale.
• Medidata (Dassault Systèmes): Provider of the Rave Clinical Trial Management System (CTMS) and adjacent eClinical suite, including EDC, eCOA, and RTSM. It is one of the two most entrenched enterprise CTMS vendors and the most direct comparable to Engility's CTMS positioning.
• Florence Healthcare: Specialist eTMF/remote site monitoring platform widely adopted among mid-market sponsors and CROs. Florence is the closest dedicated eTMF challenger to Engility eTMF and competes for the same 'unify the trial' procurement budget.
• Bio-Optronics: Long-standing vendor of CTMS (Clinical Conductor) and schedule-of-activities tools, primarily serving research sites, academic medical centers, and small/mid-sized sponsors — overlapping with PHARMASEAL's mid-market and academic customer focus.
• Phlexglobal (Cencora): Specialist TMF/eTMF services and technology provider (now part of Cencora/World Courier), with deep TMF Reference Model expertise. It is directly comparable to the Engility eTMF offering, and advisory-board member Karen Roy was previously responsible for TMF business at Phlexglobal.
• RealTime Software Solutions: Provider of CTMS and eCRF solutions for sites, CROs, and sponsors, including the RealTime-CTMS and RealTime-eCRF products. It is a direct CTMS competitor at the site-and-CRO tier where PHARMASEAL is active.

Broad incumbents

• Oracle Clinical One: Oracle's unified clinical trial platform spanning EDC, CTMS, RTSM, and analytics, offered as part of a much broader Life Sciences portfolio. It targets the same enterprise pharma buyer as PHARMASEAL but does so with a vastly larger installed base and balance sheet.
• MasterControl: Quality and compliance platform with adjacent clinical/eTMF modules serving regulated life sciences companies. It is a broader incumbent rather than a direct CTMS specialist, but it competes for the same regulated-clinical-systems budget.

Emerging players

• SimpleTrials: Lightweight CTMS/eTMF platform targeted at emerging biopharma and CROs with simple study portfolios. It targets the same mid-market, cost-sensitive buyer as PHARMASEAL with a similar 'no per-user pricing' philosophy.
• Octalsoft: End-to-end clinical trial software provider offering CTMS, EDC, eTMF, and RTSM modules to small and mid-sized sponsors. It is comparable in scope (unified CTMS+eTMF) and target market to PHARMASEAL, though typically earlier-stage accounts.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/watch?v=g2K55aGlHEk
• LinkedInlinkedin.com/company/pharmaseal
• Xx.com/pharmaseal

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Funding overview

Funding rounds5 records

Investors3 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about PHARMASEAL