What Bio-Optronics does

Bio-Optronics, founded in 1985 and headquartered in Rochester, United States, is a private healthcare software company that builds Clinical Conductor, a Clinical Trial Management System (CTMS) targeted at research sites, site networks, hospitals, and health systems. The platform addresses core research-operations pain points including budgeting, billing, financial reporting, patient recruitment and enrollment tracking, appointment scheduling, stipend management, and regulatory compliance, and is sold as an enterprise SaaS subscription via a direct field-sales motion with quote-based pricing.

The product architecture is platform-plus-modules: Clinical Conductor sits on Advarra Cloud (ISO 27001:2013 and SOC 2 Type II certified) and integrates with proprietary add-ons—eReg (21 CFR Part 11-compliant eConsent/regulatory), eSource (21 CFR Part 11-compliant eSource + EDC), CCText (HIPAA-compliant two-way SMS), and CCPay (real-time participant payment reimbursement with advanced financial analytics). The portfolio also includes OnCore (an additional CTMS for sites and institutions), APIs, and an Epic EHR integration. AI is delivered via Braid, the company's Data & AI Engine, which powers an AI- and data-backed Study Design Solution launched in 2026 and provides operational intelligence across the product suite. Governance is supported through a Council for Responsible Use of AI in Clinical Trials and the Onsemble Community network of clinical research professionals.

Bio-Optronics makes money primarily through recurring subscription fees for the Clinical Conductor CTMS platform and its add-on modules, supplemented by professional services and consulting. Go-to-market is enterprise field sales targeting clinical research sites and institutions, with named customers including Ascension Healthcare, Norton Healthcare, Velocity Clinical Research, Javara, Tekton Research, Alcanza Clinical Research, and CCT Research. The company is privately held, backed by Mainsail Partners ($30M growth investment in 2018), and operates with 51-100 employees. Its sales motion is supported by content marketing, annual Innovation Summits, the Onsemble Community, and industry PR positioning it within the broader eClinical solutions market (estimated $15.32B in 2025, projected $24.91B by 2033 at 6.26% CAGR).

Name

Bio-Optronics

Website

https://bio-optronics.com

Company type

Private

Founded year

1985

Operating status

Operating

Headcount range

11–50 employees

Short description

Bio-Optronics is a private healthcare SaaS company that sells Clinical Conductor, a Clinical Trial Management System (CTMS), to research sites, hospitals, and health systems, with integrated modules for eRegulatory, eSource, SMS engagement, and participant payments.

Ownership category

akta.pro rank

Product category

Clinical Trial Management Software (CTMS)

NAICS

Scientific Research and Development Services (5417), Computer Systems Design and Related Services (54151)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Clinical Trial Management Systems (CTMS) (HLACAOAD)

akta.pro secondary industry

Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM)

Keywords

• Clinical trial management
• Healthcare software solutions
• Regulatory compliance software
• Electronic data capture
• Clinical research payments

Headquarters

HQ city

Rochester

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations

Revenue model

1. CTMS Software Platform: Subscription-based clinical trial management system providing operational and financial efficiency tools for research sites

Go-to-market motion1 record

Distribution channels1 record

Marketing channels4 records

Core offering

Bio-Optronics develops and delivers Clinical Trial Management System (CTMS) software for healthcare and clinical research organizations. Its core product, Clinical Conductor, is a scalable CTMS that helps research sites, site networks, hospitals, and health systems manage budgeting, billing, reporting, patient recruitment, enrollment tracking, and financial operations. The platform is extended by add-on modules (eReg, eSource, CCText, CCPay) and the Braid Data & AI Engine, deployed on the Advarra Cloud platform with integrations into systems such as Epic.

Product overview

Advarra offers a platform-plus-modules architecture for clinical research management. The core offering is Clinical Conductor CTMS, a scalable clinical trial management system for research sites, hospitals, and health systems. This core platform integrates with proprietary add-on modules including eReg (regulatory management), eSource (eSource + EDC), CCText (two-way text messaging), and CCPay (participant payments). Additional site solutions include OnCore CTMS. The platform is built on Advarra Cloud with AI capabilities through Braid, Advarra's Data & AI Engine.

Differentiator

Problem solved

Functional benefit

Brands

• Clinical Conductor: Clinical Trial Management System (CTMS) designed to optimize operational and financial efficiency for research sites, site networks, hospitals, and health systems.
• CCText
• CCPay
• Onsemble Community
• Braid
• eReg
• eSource

Products and services

• Clinical Conductor CTMS A scalable Clinical Trial Management System (CTMS) designed to optimize operational and financial efficiency for research sites, site networks, hospitals, and health systems. Includes budgeting, billing, reporting, patient recruitment, enrollment tracking, and financial management tools; integrates with Advarra eReg, Advarra eSource, provides APIs, and integrates with Epic EHR.
• eReg A 21 CFR Part 11-compliant regulatory management and eConsent system designed for any size research site, integrated with Clinical Conductor CTMS.
• eSource A 21 CFR Part 11-compliant eSource + EDC system integrated with Clinical Conductor CTMS that enables research staff to capture and manage data, facilitate remote workflows, and eliminate duplicative processes.
• CCText A CTMS-embedded, HIPAA-compliant, two-way text messaging solution for centralized oversight needs of health systems, hospitals, site networks, and individual sites engaged in clinical research.
• CCPay A real-time payment reimbursement solution providing secure debit cards issued and tracked within Clinical Conductor, offering advanced financial analytics throughout the participant payment process.
• Braid (Data & AI Engine) Advarra's Data & AI Engine providing novel operational intelligence and automation in clinical trials, powering study design and other AI-enabled solutions across the product ecosystem (including Clinical Conductor CTMS).
• OnCore A CTMS solution for sites and institutions, offered alongside Clinical Conductor as part of the company's site-solutions portfolio.
• Advarra Cloud A next-generation cloud platform delivering technology solutions in an easy-to-use, fully managed cloud environment, certified to ISO 27001:2013 and SOC 2 Type II.

Quantifiable outcome

• Unbilled payments recovered that would have been prohibitive to recover manually

Named customers7 records

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration3 records

AI capability3 records

Feature7 records

Partnerships

Two partnerships are on record, tiered core.

• EpiccoreTechnology or IntegrationIntegration partnership enabling Clinical Conductor CTMS to connect with Epic EHR systems used throughout healthcare organizations, facilitating seamless data exchange between clinical research and hospital systems
• Braid (Advarra Data & AI Engine)coreTechnology or IntegrationInternal AI/data platform powering study design solutions and operational intelligence across the Advarra product ecosystem, including Clinical Conductor CTMS

Scale indicators3 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• Advarra: Larger clinical research technology and services organization under whose brand Bio-Optronics' Clinical Conductor and OnCore CTMS now sit. Comparable because Advarra operates the same CTMS products alongside IRB, IBC, and study collaboration offerings.
• Veeva Systems: Public, large-scale clinical trial and life sciences cloud platform with Veeva Vault CTMS, eTMF, and EDC. Competes most directly with Bio-Optronics' site-and-sponsor workflows and operates at materially greater scale across global pharma.
• WCG (WIRB-Copernicus Group): Clinical research services and technology provider including IRB, IBC, and clinical technology platforms. Comparable as an ecosystem player that touches research sites, sponsors, and compliance — overlapping Bio-Optronics' site solution footprint.
• Medidata Solutions (Dassault Systèmes): Long-established eClinical suite including Rave CTMS, EDC, and RTSM serving sponsors and sites. Directly comparable to Bio-Optronics' site CTMS scope, but with deeper sponsor-side functionality and a global enterprise footprint.
• Calyx (formerly Parexel informatics): Provides CTMS (Calyx CTMS / IMPACT), EDC, RTSM, and medical imaging for clinical trials. Comparable to Bio-Optronics across site-and-sponsor clinical trial operations with broader suite and global delivery.
• Oracle Health Sciences (Clinical One): Provides Clinical One CTMS/EDC and broader eClinical suite for sponsors and CROs. A direct competitor to Bio-Optronics in the site-and-sponsor CTMS category, with substantially larger R&D and global sales resources.

Direct peers

• Florence Healthcare: Site-focused eRegulatory (eReg/eBinder) and eSource platform for research sites and sponsors. Directly competes with Bio-Optronics' eReg module and adjacent to its Clinical Conductor site CTMS footprint.
• RealTime Software Solutions: Site-focused CTMS, eRegulatory, and eSource vendor serving research sites and site networks. Closely comparable to Bio-Optronics in target customer (research sites), pricing model, and feature scope.
• Endpoint Clinical: Provides Interactive Response Technology (IRT/RTSM) and eClinical software used by sponsors, CROs, and sites. Comparable to Bio-Optronics on clinical operations technology stack and shared site/sponsor buyer personas.

Emerging players

• Castor: Cloud EDC and eClinical platform with eConsent, RTSM, and decentralized trial capabilities. Overlaps with Bio-Optronics' eSource/EDC and eReg modules, particularly for academic and mid-sized sponsor sites.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/biooptronics
• Facebookfacebook.com/biooptronics
• LinkedInlinkedin.com/company/112214

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Bio-Optronics