Alfie Health

What Alfie Health does

Alfie Health was a New York-based virtual obesity management company that operated an AI-powered telehealth platform branded ObesityRx™. The proprietary technology analyzed patient medical history to determine personalized treatment strategies combining medications, lifestyle modifications, and behavioral change support, delivered alongside virtual provider visits. The company served two primary customer sets: individual consumers seeking data-driven obesity care through a direct-to-consumer telehealth channel, and enterprise healthcare clients including a large cardiology group and payer contracts spanning several states that enabled insurance-covered access to the platform.

The underlying technology stack centered on a text-based recommendation engine that ingested patient medical history and output treatment recommendations, with clinical outcomes of 10–15% average weight loss over 9 months demonstrated in a 300-patient cohort. The business model combined recurring clinical/telehealth service revenue with subscription-style payer contracts, distributed through self-serve DTC channels and direct enterprise sales.

Alfie Health raised approximately $2.6M in cumulative funding across a 2022 early round and a June 2023 $2.1M seed round co-led by Y Combinator and Nina Capital. In 2024, the company was acquired by knownwell, a weight-inclusive primary care and metabolic health provider, which integrated ObesityRx™ into its care model; standalone Alfie platform access and Alfie-affiliated clinics were subsequently shut down.

Name

Alfie Health

Legal name

Alfie Health

Website

https://joinalfie.com

Company type

Private

Founded year

2022

Operating status

Acquired

Headcount range

1–10 employees

Short description

Alfie Health was a New York-based virtual obesity management startup whose AI-powered ObesityRx™ platform analyzed patient medical history to deliver personalized medication, lifestyle, and behavioral treatment via telehealth to consumers and enterprise healthcare clients before being acquired by knownwell in 2024.

Ownership category

akta.pro rank

Product category

Virtual Obesity Management

NAICS

Diet and Weight Reducing Centers (812191)

akta.pro primary industry

Obesity Medicine & Weight Management (HLAKADAL)

akta.pro secondary industries

Cardiometabolic RPM & Chronic Disease Management (diabetes, hypertension, CHF, obesity) (HLALAFAA), Membership/Subscription Concierge Virtual Care (HLALAAAH), Weight Management & Behavior Change Education (EDAAAHAF)

Keywords

• Virtual obesity management
• Metabolic health platform
• AI telehealth services
• Weight loss treatment
• Personalized obesity care

Headquarters

HQ city

New York

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Telehealth/Clinical Services: Revenue generated from providing virtual obesity management services including personalized medical recommendations, medications, lifestyle changes, and virtual provider visits to patients.
2. Payer Contracts: Revenue from contracts with payers (insurance companies) across several states for obesity management services.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels3 records

Core offering

Alfie Health offered an AI-powered virtual obesity management platform called ObesityRx™ that analyzed patient medical history to determine personalized treatment strategies combining medications, lifestyle changes, behavioral support, and virtual provider visits. The platform integrated with payer contracts and enterprise healthcare collaborations to deliver evidence-based obesity care.

Product overview

Alfie Health offered a single unified product: the AI-powered ObesityRx™ platform for virtual obesity management. This platform combined personalized medical recommendations (including medications and lifestyle changes) with virtual provider visits and payer contracts. The ObesityRx™ technology analyzed patient medical history to determine treatment strategies for sustainable metabolic health improvements. As of 2024, the platform was acquired by knownwell and standalone access has been shut down.

Differentiator

Problem solved

Functional benefit

Brands

• ObesityRx: AI-powered technology that analyzes patient medical history to determine the most effective treatment strategies for sustainable metabolic health improvements.

Products and services

• ObesityRx™ AI-powered virtual obesity management platform that analyzes patient medical history to determine the most effective treatment strategies for sustainable metabolic health improvements, combining personalized medication and lifestyle recommendations with telehealth provider visits and behavioral change support for patients with obesity and enterprise healthcare partners.

Quantifiable outcome

• 10-15% average weight loss in 9 months across 300-patient cohort

Named customers2 records

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability2 records

Feature1 record

Partnerships

Two partnerships are on record, tiered core and minor.

• knownwellcoreStrategic or Co-development Partner · 20 June 2025knownwell acquired Alfie Health to integrate its AI-powered ObesityRx™ platform into knownwell's in-person and virtual, weight-inclusive primary care and metabolic health model. The acquisition combines Alfie's data-driven treatment strategies with knownwell's evidence-based care model.
• Large Cardiology GroupminorStrategic or Co-development PartnerCollaboration with a large cardiology group to offer integrated obesity treatment within cardiovascular care, utilizing Alfie's AI-driven system for personalized treatment and behavioral change support.

Scale indicators4 records

Recent moves5 records

Expansion highlights3 records

Direct peers

• knownwell: knownwell is the acquirer of Alfie Health and operates a weight-inclusive, in-person and virtual primary care and metabolic health platform. It is directly comparable as it now owns and integrates Alfie's ObesityRx™ platform within the same obesity and metabolic health category.
• Calibrate: Calibrate is a telehealth metabolic health platform combining clinician-led care, medication (including GLP-1s), and behavior change for weight management. Directly comparable to Alfie in offering virtual, data-driven obesity treatment to a consumer audience with enterprise/payer reach.
• Found (Found Health): Found is a virtual weight care clinic prescribing medications and providing behavioral coaching for obesity. Comparable to Alfie as a DTC-first telehealth platform with personalized, evidence-based obesity treatment plans.
• Virta Health: Virta Health is a virtual specialty care platform for metabolic diseases including obesity and type 2 diabetes, leveraging telehealth plus personalized nutrition and medication strategies. Directly comparable in clinical model and payer/enterprise contracting approach.

Broad incumbents

• Ro: Ro is a large multi-condition telehealth platform with a dedicated weight management program (Ro Body) covering obesity and GLP-1 prescribing. Comparable as a broader incumbent offering overlapping virtual obesity care alongside other verticals.
• Hims & Hers Health: Hims & Hers is a broad telehealth and wellness brand that has expanded into weight loss offerings, including access to GLP-1 medications. Comparable as a much larger incumbent in the same category, with overlapping obesity management services.
• Omada Health: Omada Health is a virtual chronic care platform serving diabetes, hypertension, and obesity via digital coaching and remote monitoring, primarily through payer and employer contracts. Comparable as a broader chronic-condition incumbent with overlapping cardiometabolic and obesity management focus.
• Noom: Noom is a digital behavior-change platform for weight management with an expanding clinical and medication-assisted offering. Comparable as a much larger incumbent in the weight management category, with overlap on the lifestyle/behavior-change component of obesity care.
• WeightWatchers: WeightWatchers is a long-established weight management brand that has expanded into telehealth, clinician services, and access to obesity medications. Comparable as a broader incumbent serving a similar weight-loss consumer base with overlapping obesity care.

Emerging players

• Lemonaid Health (now part of 23andMe): Lemonaid Health was a virtual primary care and chronic-condition platform offering telehealth visits and prescriptions, including weight-related care. Comparable as an emerging virtual care player overlapping with obesity and chronic-condition management.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat2 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/alfiehealth
• LinkedInlinkedin.com/company/alfiehealth

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds2 records

Investors4 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Alfie Health