Causeway Sensors

What Causeway Sensors does

Causeway Sensors Ltd. is a Belfast-based nanotechnology company developing biosensor platforms for bioprocess monitoring. The company's flagship product, TITAN, is a biosensor device designed for at-line, real-time quantification of IgG antibodies in bioprocess workflows, targeting biopharmaceutical manufacturers. The platform is supported by Loki, an associated software component for data tracking and analysis within the TITAN system.

The company was spun out of Queen's University Belfast in 2016 and is built on proprietary nanosensor research originating from the university's nanotechnology work. Causeway is currently operating a beta program for TITAN with bioprocess industry partners, positioning the platform to address quality and efficiency gaps in antibody-based therapeutic manufacturing, where traditional off-line IgG assays create process bottlenecks and delay release decisions. The pivot from earlier disease-detection applications to bioprocess monitoring reflects a deliberate refocus on biopharma commercial traction.

The business model centers on instrument sales to biopharmaceutical enterprises, likely augmented by recurring software and consumables revenue, validated through industry partnerships including with CPI (Centre for Process Innovation), Fusion Antibodies, and the Pharmaceutical Manufacturing Technology Centre (PMTC). Causeway has raised approximately £3.3 million across multiple funding rounds led by Kernel Capital and supported by UK Research and Innovation, Innovate UK, and QUBIS (Queen's University's commercialization arm). The company is led by CEO Antony Murphy, Chairman Bob Pollard, and Finance Director Deirdre Francis.

Name

Causeway Sensors

Legal name

Causeway Sensors Ltd.

Website

https://causewaysensors.com

Company type

Private

Founded year

2016

Operating status

Operating

Headcount range

1–10 employees

Short description

Causeway Sensors is a Belfast-based nanotechnology company spun out of Queen's University Belfast, developing the TITAN biosensor platform for real-time IgG quantification in biopharmaceutical bioprocess monitoring.

Ownership category

akta.pro rank

Product category

Bioprocess Analytics Instruments

NAICS

Analytical Laboratory Instrument Manufacturing (334516), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (33451), Other Measuring and Controlling Device Manufacturing (334519)

SIC

Laboratory Analytical Instruments (3826), Industrial Instruments For Measurement, Display, And Control (3823), Measuring & Controlling Devices, Nec (3829)

akta.pro primary industry

Analytical Development & QC Testing (Release/Stability/Potency) (HLAGAGAF)

akta.pro secondary industries

Metrology, Calibration & Testing Equipment (Balances, pH/DO, Standards) (HLAGAIAL), Process Analytical Instrumentation (Gas analyzers, spectroscopy, pH/ORP, conductivity) (IMAGAFAE)

Keywords

• Bioprocess analytics
• Nanosensor technology
• IgG quantification
• Bioprocess monitoring
• Biopharmaceutical sensors

Headquarters

HQ city

Belfast

HQ country

United Kingdom

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure

Revenue model

1. TITAN Hardware System Sales: Sale of TITAN instrument - a compact at-line bioprocess monitoring device. Includes reusable biosensor chips valid for 100 measurements.
2. Consumables and Assay Kits: Ongoing revenue from consumables and assay kits for the TITAN system. Biosensors are reusable but require replacement over time.
3. Software Suite (Loki): Included with TITAN hardware - provides data export and tracking capabilities. Part of the overall system offering.

Pricing tiers

Go-to-market motion2 records

Distribution channels1 record

Marketing channels4 records

Core offering

Causeway Sensors develops and sells the TITAN bioprocess monitor, a compact at-line biosensor instrument that delivers real-time IgG quantification directly from bioreactor samples within 10 minutes and without sample preparation. The system pairs reusable nanosensor biosensor chips (valid for 100 measurements) with the included Loki software suite for Critical Quality Attribute data export and tracking, and is sold to biopharmaceutical process scientists and bioprocess manufacturers as an alternative to centralized HPLC/BLI laboratory analysis.

Product overview

Causeway Sensors offers the TITAN system, a compact bioprocess monitoring platform for at-line, real-time IgG quantification. The product portfolio consists of the TITAN hardware device—a reusable biosensor capable of 100 measurements per chip—and the Loki software suite, which provides data export and tracking capabilities for Critical Quality Attributes (CQAs).

Differentiator

Problem solved

Functional benefit

Products and services

• TITAN Bioprocess Monitor TITAN is a compact, at-line biosensor device that performs real-time IgG quantification directly from bioreactor samples without sample preparation, delivering titre data within 10 minutes and providing 95%+ correlation to HPLC and BLI reference methods. It is designed for process scientists in biopharmaceutical manufacturing who need rapid, lab-comparable analytical results inside the production suite, and uses reusable biosensor chips valid for 100 measurements.

Quantifiable outcome

• 95%+ correlation to HPLC and BLI reference methods
• +3 more outcomes

Segments1 record

Ideal customer profiles1 record

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Four partnerships are on record, tiered core and minor.

• Centre for Process Innovation (CPI)coreStrategic or Co-development PartnerCPI is a partner in collaborative work on bioprocess technology evaluation. CPI has published application notes evaluating the TITAN system for monoclonal antibody quantification in bioprocessing, demonstrating co-development and validation partnership.
• Queen's University BelfastcoreStrategic or Co-development PartnerOrigin of the company's nanotechnology platform. Founder Bob Pollard is seconded from his position as Senior Lecturer at Queen's. R&D laboratories located at Queen's University Belfast's International Research Centre for Experimental Physics.
• QUBISminorStrategic or Co-development PartnerQueen's University Belfast's technology transfer and commercialization arm, facilitating the spin-out from academic research.
• PMTCminorStrategic or Co-development PartnerListed as a partner, likely related to process or manufacturing technology collaboration.

Scale indicators7 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Repligen: Repligen is a pure-play bioprocess-focused company offering analytics and process technologies (including spectroscopy-based titer sensors like the SoloVPE) directly to biomanufacturers. Causeway's TITAN at-line IgG biosensor targets the same analytical QC bottleneck that Repligen's at-line titer tools address, making them the closest direct competitor for bioprocess analytics budget.
• Bio-Techne (ProteinSimple): Bio-Techne's ProteinSimple division offers protein characterization and quantification tools (e.g., Simple Western/Jess) used in bioprocess and analytical development. TITAN competes for the same protein quantification workflow budget in biopharma manufacturing with a faster, at-line alternative.
• Aber Instruments: Aber Instruments is a UK-based bioprocess sensor company specializing in real-time biomass and capacitance-based process monitoring. It is a directly comparable UK bioprocess sensor peer and a likely collaborator/competitor for the same biomanufacturing analytical instrumentation buyer.

Broad incumbents

• Cytiva (Biacore): Cytiva owns Biacore, the BLI/SPR-based antibody characterization platform that TITAN explicitly benchmarks against (95%+ correlation claim). Cytiva is the entrenched incumbent for protein interaction and titre analytics in bioprocess and drug development; Causeway positions TITAN as a faster, simpler alternative for at-line use cases.
• Sartorius (ForteBio): Sartorius acquired ForteBio (BLI instruments for protein quantification) and sells broadly into bioprocess with a large installed base of sensors and PAT tools. Like Cytiva, it represents both a reference standard (BLI) that TITAN benchmarks against and a competitor for at-line bioprocess analytics budgets.
• Thermo Fisher Scientific: Thermo Fisher is the dominant analytical instrument manufacturer (HPLC, mass spectrometry, bioprocess analytics) and a key incumbent Causeway must displace. Its size, global service network, and existing bioprocess footprint make it both a benchmarking reference (HPLC correlation) and a competitive threat.
• Mettler-Toledo: Mettler-Toledo manufactures process analytical instrumentation (pH, dissolved oxygen, conductivity, density, inline titrators) used across pharma and biotech manufacturing. It competes for the broader PAT and at-line analytics budget that TITAN targets and represents a potential strategic acquirer of in-process analytical technologies.
• Hamilton Company: Hamilton produces process sensors (pH, DO, biomass/viability via in-line probes) widely used in biopharmaceutical manufacturing. It is a comparable peer in the bioprocess sensor category, with established biopharma qualification and a broad portfolio Causeway would need to displace or sit alongside.

Emerging players

• Cardea Bio (formerly Nanomedical Diagnostics): Cardea Bio builds graphene-based biosensor chips and electronic readout platforms for biomolecule detection. Like Causeway, it uses nanoscale materials (graphene vs Causeway's proprietary nanosensor) for sensitive biomolecular detection and is an emerging competitor in next-generation biosensor instrumentation.
• Flownamics: Flownamics provides automated at-line sampling and bioprocess analytics platforms that move samples from bioreactors to analytical devices without manual handling. It addresses the same 'bottleneck in bioprocess analytics' pain point Causeway targets, complementing or competing with TITAN as part of an automated PAT workflow.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/causewaysensors
• LinkedInlinkedin.com/company/causeway-sensors-limited

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds5 records

Investors4 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Causeway Sensors