Xyall
Xyall B.V. is a Dutch MedTech company that develops and sells automated tissue dissection systems (Tissector HT, Tissector Table Top, and Annotation Suite) for molecular pathology laboratories, serving commercial diagnostic labs, academic medical centers, and pharma research institutions globally.
- Company typePrivate
- Founded2018
- HeadquartersEindhoven, Netherlands
- Headcount1–10
- GTM typeB2B
- OfferingHardware or Manufacturing
What Xyall does
Xyall B.V. is a Dutch MedTech company headquartered in Eindhoven, Netherlands, founded in August 2018 by Guido du Pree and Hans van Wijngaarden—both former senior managers in Philips Healthcare's global digital pathology business. The company develops and commercializes the Tissector family of automated tissue dissection systems, which address the manual, error-prone tumor tissue dissection step in molecular pathology by integrating high-resolution slide imaging, image registration algorithms, precision robotics, and digital pathology workflow software. Its product portfolio comprises three integrated products: the Tissector High Throughput (1,800-slide capacity, >80 slides/hour, <0.1mm accuracy, 3 hours unattended) for large commercial molecular diagnostic labs; the Tissector Table Top (72-slide capacity, >30 slides/hour) for hospital-based labs; and the Tissector Annotation Suite, a remote pathologist workstation integrated with LIMS and IMS systems.
Xyall generates revenue primarily through direct enterprise sales of Tissector instruments (B2B IVD medical devices, quote-based, multi-year contracts) supplemented by recurring consumables (disposable scraping heads required per case) and software licensing through the Annotation Suite. Go-to-market combines direct field sales targeting high-volume commercial labs, academic medical centers, and hospital-based molecular pathology labs with channel partnerships—Motic for China and broader Asia, and Indica Labs for integrated HALO AP digital pathology workflow sales. The installed base includes 15+ US molecular pathology laboratories, with named reference customers including Labcorp, LUMC (Leiden University Medical Center), and InnoSIGN. The company holds ISO 13485:2016 certification (obtained April 2021, renewed January 2024) and has raised approximately €18.6 million across three funding rounds through February 2026.
Xyall firmographics
Firmographics- Name
- Xyall
- Legal name
- Xyall B.V.
- Website
- https://xyall.com
- Company type
- Private
- Founded year
- 2018
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- Xyall B.V. is a Dutch MedTech company that develops and sells automated tissue dissection systems (Tissector HT, Tissector Table Top, and Annotation Suite) for molecular pathology laboratories, serving commercial diagnostic labs, academic medical centers, and pharma research institutions globally.
- Ownership category
- akta.pro rank
Xyall industry classification
Industry- Product category
- Molecular Pathology Instrumentation
- NAICS
- Medical and Diagnostic Laboratories (6215), Diagnostic Imaging Centers (621512)
- SIC
- In Vitro & In Vivo Diagnostic Substances (2835), Services-Medical Laboratories (8071), Surgical & Medical Instruments & Apparatus (3841)
- akta.pro primary industry
- Anatomic Pathology LIS & Digital Pathology Workflow (HLACAMAB)
- akta.pro secondary industries
- Anatomic Pathology & Histology/Cytology IVD (Tissue Diagnostics) (HLAHAAAE), Pathology Reporting, Synoptic Templates & Cancer Registry Interfaces (HLACAMAJ)
Keywords
Where Xyall is headquartered
LocationHeadquarters
- HQ city
- Eindhoven
- HQ country
- Netherlands
- HQ region
- Europe
Offices2 records
Markets served
Xyall business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Supply Chain, Technology or R&D, Marketing or Sales, Operations, Infrastructure
Revenue model
- Tissector Instrument Sales: Sale of Tissector High Throughput and Tissector Table Top automated tissue dissection instruments to molecular pathology laboratories. The company manufactures and sells these IVD medical devices globally.
- Consumables (Scraping Heads): Recurring disposable consumables (scraping heads) required for each dissection case. Each case requires a new scraping head for cross-contamination prevention, creating recurring revenue from the installed base of instruments.
- Software Licenses (Annotation Suite): The Tissector Annotation Suite is bundled with instruments as workstation software for pathologists. Software may also be licensed separately or as part of integrated digital pathology workflows with partners such as Indica Labs HALO AP.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Multi-year contract | Enterprise medical device — no public pricing disclosed |
Go-to-market motion1 record
Distribution channels3 records
Marketing channels6 records
Xyall product offering
Product offeringCore offering
Xyall develops and manufactures the Tissector family of automated tissue dissection systems for molecular pathology laboratories. The Tissector High Throughput handles 1,800 slides and dissects over 80 slides per hour for high-volume commercial diagnostic labs, while the Tissector Table Top is a compact 72-slide system for small and medium hospital-based pathology labs. The Tissector Annotation Suite is a digital pathology workstation where pathologists remotely annotate regions of interest that are then automatically transferred to dissection slides via image registration for robotic scraping, replacing the manual tumor tissue macrodissection step used prior to DNA/RNA extraction and genomic profiling.
Product overview
Xyall offers a family of automated tissue dissection solutions for molecular pathology laboratories. The product portfolio consists of the Tissector High Throughput system for large commercial molecular diagnostic laboratories, the Tissector Table Top system for small to medium sized hospital-based labs, and the Tissector Annotation Suite which serves as the pathologist workstation for all systems. All three products work together as an integrated solution, bridging the gap between histopathology and molecular pathology by automating the traditionally manual tissue dissection step in diagnostics. The Tissector solutions integrate high-resolution imaging, image registration, precision robotics, and workflow optimization.
Differentiator
Problem solved
Functional benefit
Brands
- Tissector: Automated tissue dissection system family including Tissector High Throughput for high-volume laboratories, Tissector Table Top for small to medium-sized labs, and Tissector Annotation Suite for remote pathologist annotation and workflow management.
Products and services
- Tissector High Throughput Industrial-scale automated tissue dissection system for high-volume molecular diagnostic laboratories. Holds up to 1,800 slides, dissects over 80 slides per hour with accuracy better than 0.1 mm, and runs up to 3 hours unattended. Fully integrated with LIMS/IMS and supports multiple sample tube formats.
- Tissector Table Top Compact bench-top automated tissue dissection system for small to medium-sized molecular pathology laboratories. Holds 72 slides, dissects over 30 slides per hour with accuracy better than or equal to 0.1 mm, runs more than 2 hours uninterrupted, and supports batch operation with cases addable without interrupting operation.
- Tissector Annotation Suite Digital pathology workstation that lets pathologists remotely view and annotate cases, mark regions of interest at any magnification, and automatically transfer annotations to dissection slide images via image registration algorithms. Fully integrated with LIMS and IMS systems and supports any digital pathology file format.
Quantifiable outcome
- Superior to manual methods in scraping FFPE tissue within defined ROIs, minimizing excess paraffin, and delivering consistent tissue sections for downstream DNA/RNA extraction and comprehensive genomic and immune profiling (Labcorp study, SLAS2024)
- +2 more outcomes
Companies that use Xyall
Customer profileNamed customers3 records
Segments3 records
Ideal customer profiles3 records
Xyall technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration3 records
AI capability5 records
Feature6 records
Xyall partnerships and signals
Strategic signalPartnerships
Four partnerships are on record, tiered core and minor.
- Indica LabscoreGlobal strategic partnership bridging histology and molecular pathology. Combines Xyall's automated Tissector tissue dissection with Indica Labs' AI-powered HALO AP anatomic pathology image management and workflow software. HALO AP annotations are automatically simplified and transferred to Xyall's Tissector for tumor tissue dissection. Combined solution already in use in large commercial lab settings.
- LUMC (Leiden University Medical Center)minorAcademic collaboration with LUMC (with support of Indica Labs) on AI-enabled automated tissue macro-dissection in molecular pathology. Joint investigation presented at ECDP 2025 in Barcelona showed digital annotation and robotic dissection led to significant increases in tumor cellularity and VAF in NGS results.
- MoticcoreMulti-year strategic partnership with world leader in microscopy and digital pathology systems. Motic provides digital pathology expertise, workflow integration, and scalable manufacturing capabilities. Joint product development for automated table-top tumor tissue dissection for hospital-based labs. Includes reseller and support agreement to accelerate delivery into Chinese and Asian markets.
- Sioux TechnologiescoreStrategic partner providing high-tech engineering expertise, including high-precision medical robotics and machine learning. First Xyall systems were manufactured at the Sioux Technologies facility in Eindhoven. Sioux has 750+ engineers providing software, mathware, mechatronics, and electronics expertise. Participated as investor in Series A, Series B, and 2026 funding rounds.
Scale indicators5 records
Recent moves6 records
Expansion highlights5 records
Xyall competitors and assessment
Company assessmentBroad incumbents
- Leica Biosystems (Danaher): Major pathology IVD and digital pathology player owned by Danaher, offering laser capture microdissection (LMD) systems, tissue processors, and staining instruments. Directly competes with Xyall in tissue dissection workflows and serves the same molecular pathology laboratory customers globally with substantially larger scale.
- Roche Diagnostics (Ventana): Global leader in tissue diagnostics through its Ventana product line, offering staining systems, digital pathology scanners, and companion diagnostic assays. Competes with Xyall as the dominant incumbent in anatomic pathology IVD and has the resources to develop or acquire automated dissection technology.
- Hamamatsu Photonics: Manufacturer of NanoZoomer whole-slide imaging scanners and digital pathology solutions used by molecular pathology laboratories. Competes with Xyall's Tissector Annotation Suite in the digital pathology workflow space and serves the same enterprise laboratory customers.
- Akoya Biosciences: Provider of spatial biology solutions including multiplexed tissue staining and imaging platforms (Opal/PhenoCycler) for molecular pathology. Comparable as a tissue-based molecular diagnostics company serving precision oncology applications, though focused on spatial analysis rather than bulk dissection.
- Philips Digital Pathology: Global digital pathology platform provider of IntelliSite scanners and pathology workflow software, and the former employer of Xyall's founders. Serves the same molecular pathology enterprise customers and competes in the digital annotation and workflow space integrated with the Tissector.
Direct peers
- Molecular Machines & Industries (MMI): Specialized provider of laser capture microdissection (LCM) systems and cell manipulation tools for molecular pathology and biomedical research. Directly competes with Xyall's Tissector in the tissue dissection step, though MMI's technology is more research-focused versus Xyall's high-throughput diagnostic positioning.
- 3DHISTECH: Hungarian-based provider of digital pathology scanners, slide management systems, and tissue microarray instruments serving pathology laboratories. Comparable to Xyall as a European-headquartered digital pathology innovator serving molecular pathology workflows with mid-size scale.
- Indica Labs: Provider of HALO AP anatomic pathology image management and AI-powered annotation software, in a global strategic partnership with Xyall for integrated HALO AP + Tissector workflows. Comparable as a digital pathology platform serving the same molecular pathology customers, with overlapping product/market scope.
- Motic: World leader in microscopy and digital pathology systems, in a multi-year strategic partnership with Xyall for joint product development and Asia/China distribution. Comparable as a pathology instrument and digital pathology provider with overlapping customer base in molecular pathology laboratories.
Emerging players
- Fluidigm (now Standard BioTools): Provider of mass cytometry and molecular biology tools, including tissue imaging and molecular sample preparation technologies. Adjacent to Xyall in molecular pathology sample preparation, though focused on single-cell and proteomics applications rather than bulk tissue dissection.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
Xyall social profiles
Digital presenceXyall compliance and trust
Trust signalCompliance1 record
Xyall financial estimates
Financial estimateRevenue estimate
Valuation estimate
Xyall leadership team
Management profileNumber of profiles
Profiles9 records
Xyall funding detail
Funding detailFunding overview
Funding rounds3 records
Investors6 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Xyall M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Xyall
What does Xyall do?
Xyall develops and manufactures the Tissector family of automated tissue dissection systems for molecular pathology laboratories. The Tissector High Throughput handles 1,800 slides and dissects over 80 slides per hour for high-volume commercial diagnostic labs, while the Tissector Table Top is a compact 72-slide system for small and medium hospital-based pathology labs. The Tissector Annotation Suite is a digital pathology workstation where pathologists remotely annotate regions of interest that are then automatically transferred to dissection slides via image registration for robotic scraping, replacing the manual tumor tissue macrodissection step used prior to DNA/RNA extraction and genomic profiling.
Is Xyall a public or private company?
Xyall is a private company. It is classified as venture growth investor backed and is currently operating.
When was Xyall founded?
Xyall was founded in 2018. It employs 1 to 10 people.
Where is Xyall based?
Xyall is headquartered in Eindhoven, Netherlands, in the Europe region.
How does Xyall make money?
Three revenue lines are on record. Tissector Instrument Sales are the primary driver. The others are consumables (Scraping Heads) and software Licenses (Annotation Suite).
Who are Xyall's main competitors?
Broad incumbents on record are Leica Biosystems (Danaher), Roche Diagnostics (Ventana), Hamamatsu Photonics, Akoya Biosciences and Philips Digital Pathology. Direct peers are Molecular Machines & Industries (MMI), 3DHISTECH, Indica Labs and Motic. Fluidigm (now Standard BioTools) is listed as an emerging player.
Does Xyall have an API?
No public API is recorded for Xyall.
What industry is Xyall in?
Xyall's product category is Molecular Pathology Instrumentation. Its primary akta.pro industry code is HLACAMAB, Anatomic Pathology LIS & Digital Pathology Workflow, with a secondary code of HLAHAAAE, Anatomic Pathology & Histology/Cytology IVD (Tissue Diagnostics). Its NAICS code is 6215 and its SIC code is 2835.