YPrime
YPrime provides configurable eCOA, IRT, and eConsent software platforms for global clinical trials, serving pharmaceutical sponsors, biotechs, and CROs across 100+ countries through proprietary AI-powered localization, 24/7 expert support, and integrated participant engagement tools.
- Company typePrivate
- Founded2008
- HeadquartersMalvern, United States
- Headcount101–250
- GTM typeB2B
- OfferingSoftware
What YPrime does
YPrime is a privately held clinical trial technology company founded in 2006 and headquartered in Malvern, Pennsylvania, operating as Y-Prime, LLC with a wholly-owned UK subsidiary (Y-Prime UK Ltd.). The company provides an integrated eClinical platform built around three core products — eCOA (Electronic Clinical Outcome Assessment), IRT (Interactive Response Technology), and eConsent — supplemented by participant engagement tools, consulting services, and 24/7/365 in-house expert support. YPrime reports approximately 1,000 studies implemented globally across more than 100 countries and 19 therapeutic areas, with more than 125,000 patients engaged on its platform and customers including top-15 pharmaceutical sponsors, emerging biotechs, CROs, and clinical research sites.
The platform is built on a fully configurable, no-code architecture accessible across devices and integrates eCOA, IRT, and eConsent workflows to support complex global protocols. Differentiated technical components include a proprietary AI Migration Tool that automates eCOA localization (74% reduction in migration errors, 67% faster review cycles), an AI Calculation Engine that uses natural language input to configure clinical trial data calculations, a Participant Hub with a 'For You' engagement page, Advanced eCOA Oversight with attributable electronic signatures aligned to EMA, FDA, and ICH guidelines, and a Data Suite providing near real-time reporting with inspection-ready audit trails. The platform is sold via direct enterprise field sales, RFP- and demo-driven engagement, and ecosystem integrations such as the Advarra Study Collaboration partnership, which provides single sign-on access to more than 225,000 study team members.
YPrime's revenue model combines subscription-based platform licensing (eCOA, IRT, eConsent) with professional consulting services and bundled global support, priced via quote-based enterprise contracts tailored to study complexity, scope, and duration. The company is structured as a privately held LLC with no disclosed funding rounds, no parent company, and no public listing, suggesting it is founder- or management-owned and operating cash-flow positive. Recent strategic activity has centered on AI-enabled product launches, a major platform refresh, and ecosystem partnerships that broaden distribution without reliance on external capital.
YPrime firmographics
Firmographics- Name
- YPrime
- Legal name
- Y-Prime, LLC
- Website
- https://yprime.com
- Company type
- Private
- Founded year
- 2008
- Operating status
- Operating
- Headcount range
- 101–250 employees
- Short description
- YPrime provides configurable eCOA, IRT, and eConsent software platforms for global clinical trials, serving pharmaceutical sponsors, biotechs, and CROs across 100+ countries through proprietary AI-powered localization, 24/7 expert support, and integrated participant engagement tools.
- Ownership category
- akta.pro rank
YPrime industry classification
Industry- Product category
- eClinical Technology / Clinical Trial Software
- NAICS
- Computer Systems Design Services (541512)
- SIC
- Services-Prepackaged Software (7372)
- akta.pro primary industry
- Randomization & Trial Supply Management (RTSM/IRT/IVRS/IWRS) (HLACAOAC)
- akta.pro secondary industry
- Decentralized/Hybrid Trial Enablement (DCT) Platforms (HLACAOAL)
Keywords
Where YPrime is headquartered
LocationHeadquarters
- HQ city
- Malvern
- HQ country
- United States
- HQ region
- North America
Offices5 records
Markets served
YPrime business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Personnel, Technology or R&D, Operations, Marketing or Sales
Revenue model
- eClinical Technology Platform (eCOA, IRT, eConsent): SaaS/platform licensing model for clinical trial technology. The company provides configurable software platforms for electronic data capture in clinical trials, with implementation, configuration, and ongoing platform access as core revenue components.
- Consulting Services: Expert guidance services extending the clinical trial technology platform, including process optimization, technology alignment with protocol and regulatory requirements, system integration, and data workflow consulting.
- 24/7/365 Global Support: In-house support desk staffed by eClinical experts providing round-the-clock assistance to sponsors, CROs, and clinical research sites, bundled with platform services.
Go-to-market motion2 records
Distribution channels3 records
Marketing channels7 records
YPrime product offering
Product offeringCore offering
YPrime provides a unified eClinical technology platform for global clinical trials, delivering enterprise-grade eCOA (Electronic Clinical Outcome Assessment), IRT (Interactive Response Technology), and eConsent solutions, complemented by participant engagement tools and clinical trial consulting services. The platform is designed to accelerate study startup, support complex protocols, and provide inspection-ready data across 100+ countries.
Product overview
YPrime offers a unified Clinical Trial Technology Platform comprising four core products: eCOA (Electronic Clinical Outcome Assessment), IRT (Interactive Response Technology), eConsent, and Participant Engagement. The platform is built with configurable architecture and integrated data flows for global clinical trial execution. Core modules include eCOA for patient-reported data capture, IRT for randomization and supply management, and eConsent for enrollment. Additional offerings include the Participant Hub (an in-app engagement tool), Advanced eCOA Oversight (for investigator accountability), Data Suite (for near real-time reporting), and AI-powered tools including the AI Calculation Engine and AI Migration Tool. The company also provides consulting services to extend the platform's capabilities.
Differentiator
Problem solved
Functional benefit
Products and services
- Clinical Trial Technology Platform Unified eClinical technology platform integrating eCOA, IRT, and eConsent solutions with configurable architecture, integrated data flows, and consistent global delivery across 100+ countries, sold to pharmaceutical sponsors, biotechs, and CROs.
- eCOA (Electronic Clinical Outcome Assessment) Enterprise-grade electronic clinical outcome assessment platform for capturing patient-reported, clinician-reported, observer-reported, and performance outcomes with 100% configurable, no-code design accessible across devices. Accelerates study startup timelines by approximately 50%.
- IRT (Interactive Response Technology) Industry-leading interactive response technology platform supporting complex trial designs, rapid protocol updates, randomization, and drug supply management without operational bottlenecks. Used in global vaccine, cardiovascular, and large-scale pharmaceutical trials.
- eConsent Intuitive electronic informed consent platform that streamlines clinical trial enrollment, improves patient understanding of study requirements, and reduces site burden through user-friendly design and regulatory compliance.
- Participant Engagement Patient engagement solutions embedded within eCOA and eConsent workflows, leveraging user-friendly design, personalization, and behavioral science to drive clinical trial participant retention and adherence.
- Consulting Services Clinical trial consulting services that extend the technology platform with expert guidance on process optimization, technology alignment with protocol and regulatory requirements, system integration, and data workflow management.
- Participant Hub In-app participant experience within the eCOA platform featuring a 'For You' page that centralizes study information, visit schedules, task tracking, and embedded protocol guidance to improve clinical trial adherence and reduce dropout rates.
- AI Migration Tool Proprietary AI-powered tool for eCOA localization that automates migration of translated assessments into eCOA software, reducing errors by 74% and accelerating localization review cycles by 67% across 15 studies in 11 languages.
Quantifiable outcome
- 74% reduction in eCOA migration errors with AI-enabled workflows across 15 studies in 11 languages
- +6 more outcomes
Companies that use YPrime
Customer profileNamed customers10 records
Segments8 records
Ideal customer profiles3 records
YPrime technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability5 records
Feature8 records
YPrime partnerships and signals
Strategic signalPartnerships
Two partnerships are on record, tiered core and supporting.
- AdvarracoreYPrime is integrated as one of five eClinical technology partners in Advarra's Study Collaboration solution, providing single sign-on (SSO) access for sponsors, CROs, and research sites to access YPrime eCOA alongside EDC, eConsent, IRT/RTSM, payments, and patient engagement tools. More than 225,000 study team members use the platform, with the expansion designed to reduce administrative burden, improve adoption, and strengthen security through centralized access controls.
- Clinical Supply Consulting (CSC)supportingCSC partnered with YPrime to execute a focused, risk-based UAT strategy for IRT implementations, providing dedicated UAT support and execution expertise to help streamline coordination, testing workflows, and issue resolution during validation. The partnership enabled accelerated validation while preserving rigor and oversight required for complex IRT and eCOA implementations.
Scale indicators12 records
Recent moves6 records
Expansion highlights5 records
YPrime competitors and assessment
Company assessmentEmerging players
- Castor: Cloud-based eClinical platform with EDC, eCOA, and eConsent offerings positioned as a modern, configurable alternative — partial overlap with YPrime's eCOA and eConsent products at smaller and emerging biotech customers.
- ClinOne: Patient-centric DCT platform offering eConsent, eCOA, remote patient engagement, and connected device integrations — overlapping with YPrime's Participant Hub and eConsent capabilities in decentralized trial use cases.
Broad incumbents
- IQVIA: Largest CRO with proprietary eClinical technology stack including EDC, RTSM, and eCOA; competes with YPrime both as a buyer of third-party platforms and as a vendor offering integrated clinical technology solutions.
- Veeva Systems: Large life-sciences cloud platform whose Vault CDB and Vault eCOA offerings compete head-to-head with YPrime's IRT and eCOA as part of a broader clinical, regulatory, and commercial suite.
- Oracle Health Sciences (Clinical One / InForm): Broad incumbent offering EDC (InForm), RTSM, eCOA, and safety in an integrated platform; competes with YPrime on enterprise sponsor RFPs with significantly greater scale and integration depth.
Direct peers
- Signant Health: Specialist eCOA, eConsent, and patient engagement vendor (formed from CRF Health + Bracket) with comparable focus on configurable clinical outcome assessments and global trial deployment.
- Clario: Direct eCOA and decentralized clinical trial technology competitor formed from ERT and Bioclinica, offering electronic outcome assessments, imaging, and respiratory services to global pharma sponsors.
- Suvoda: Specialist IRT/RTSM and eCOA vendor for complex clinical trials — directly comparable to YPrime's IRT product and competes for similar oncology and rare disease trial mandates.
- Medidata Solutions (Dassault Systèmes): Industry-leading eClinical platform offering Rave EDC, Rave eCOA, and RTSM/IRT — directly competes with YPrime's eCOA and IRT products for global pharmaceutical sponsor business at much larger scale.
- Bio-Optronics: Clinical trial workflow technology provider with eCOA, CTMS, and scheduling solutions; competes with YPrime particularly in mid-sized sponsor and academic trial segments.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks5 records
Key highlights7 records
Customer concentration
YPrime social profiles
Digital presenceYPrime financial estimates
Financial estimateRevenue estimate
Valuation estimate
YPrime leadership team
Management profileNumber of profiles
Profiles7 records
YPrime subsidiaries and ownership
Company hierarchySubsidiaries1 record
YPrime funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
YPrime M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about YPrime
What does YPrime do?
YPrime provides a unified eClinical technology platform for global clinical trials, delivering enterprise-grade eCOA (Electronic Clinical Outcome Assessment), IRT (Interactive Response Technology), and eConsent solutions, complemented by participant engagement tools and clinical trial consulting services. The platform is designed to accelerate study startup, support complex protocols, and provide inspection-ready data across 100+ countries.
Is YPrime a public or private company?
YPrime is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was YPrime founded?
YPrime was founded in 2008. It employs 101 to 250 people.
Where is YPrime based?
YPrime is headquartered in Malvern, United States, in the North America region.
How does YPrime make money?
Three revenue lines are on record. eClinical Technology Platform (eCOA, IRT, eConsent) is the primary driver. The others are consulting Services and 24/7/365 Global Support.
Who are YPrime's main competitors?
Emerging players on record are Castor and ClinOne. Broad incumbents are IQVIA, Veeva Systems and Oracle Health Sciences (Clinical One / InForm). Direct peers are Signant Health, Clario, Suvoda, Medidata Solutions (Dassault Systèmes) and Bio-Optronics.
Does YPrime have an API?
No public API is recorded for YPrime.
What industry is YPrime in?
YPrime's product category is eClinical Technology / Clinical Trial Software. Its primary akta.pro industry code is HLACAOAC, Randomization & Trial Supply Management (RTSM/IRT/IVRS/IWRS), with a secondary code of HLACAOAL, Decentralized/Hybrid Trial Enablement (DCT) Platforms. Its NAICS code is 541512 and its SIC code is 7372.