ONFAB
ONFAB designs and manufactures bespoke, single-use flexible containment isolator systems that retrofit to existing pharmaceutical equipment to safely handle high potent APIs at OEB 4 and OEB 5 levels, serving global pharma manufacturers and CDMOs from facilities in the UK, USA and Spain.
- Company typePrivate
- Founded2004
- HeadquartersMiddlewich, United Kingdom
- Headcount1–10
- GTM typeB2B
- OfferingHardware or Manufacturing
What ONFAB does
ONFAB Limited is a UK-headquartered designer and manufacturer of bespoke, single-use flexible containment isolator systems used in pharmaceutical and biopharmaceutical manufacturing processes involving high potent active pharmaceutical ingredients (HPAPIs). Founded in 2004 and operating from manufacturing facilities in Middlewich (UK), Eden Prairie, Minnesota (USA), and Albacete (Spain), the company engineers flexible polymer-film enclosures (using PVC, polyurethane and polyethylene) that retrofit to approximately 98% of existing pharmaceutical process equipment, delivering containment performance at OEB 4 and OEB 5 levels (typically below 30 ng/m³) at roughly one-tenth the cost of rigid isolator alternatives.
The product portfolio comprises more than 20 SKUs across three families — flexible process isolators (weighing/dispensing, milling, granulating, drying, coating, encapsulation, API synthesis, spray drying, centrifuge, reactor charge), flexible standalone isolators (including pop-up, nitrogen and ADC variants), and accessories such as the CLASP liner tie system, fan sets, venturi air ejectors and pressure alarms — alongside the Patient Isolation Dome developed for healthcare use. ONFAB's value proposition centres on eliminating cleaning validation, enabling rapid batch changeovers between potent and non-potent compounds, and providing GMP-compliant environmental conditioning for high-containment processes, supported by ISO 9001-certified operations.
The company monetises primarily through one-time equipment sales of custom-designed isolators, supplemented by installation, training, IQ/OQ professional services, ongoing maintenance, and recurring consumable liner revenue. It sells directly through its own sales directors (UK and USA) and an internal installation team, and indirectly through 10+ distributors across North America, Europe, the Middle East, South Asia, East Asia, Southeast Asia and Oceania. Customers include global pharmaceutical manufacturers (Sanofi, BASF, GSK, AstraZeneca, Pfizer) and CDMOs such as Quay Pharma and Bluepharma. Since November 2023, ONFAB has operated as a subsidiary of Savillex Life Sciences, sitting alongside the Savillex and Optimum Processing brands, with new CEO Eric Giesing (appointed November 2024) and CFO Steve Harding (joined 2025) leading a renewed phase of US and European expansion.
ONFAB firmographics
Firmographics- Name
- ONFAB
- Legal name
- ONFAB Limited
- Website
- https://onfab.co.uk
- Company type
- Private
- Founded year
- 2004
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- ONFAB designs and manufactures bespoke, single-use flexible containment isolator systems that retrofit to existing pharmaceutical equipment to safely handle high potent APIs at OEB 4 and OEB 5 levels, serving global pharma manufacturers and CDMOs from facilities in the UK, USA and Spain.
- Ownership category
- akta.pro rank
ONFAB industry classification
Industry- Product category
- Pharmaceutical containment equipment
- NAICS
- Industrial and Commercial Fan and Blower and Air Purification Equipment Manufacturing (333413), Automatic Environmental Control Manufacturing for Residential, Commercial, and Appliance Use (334512)
- SIC
- Industrial & Commercial Fans & Blowers & Air Purifing Equip (3564), Laboratory Apparatus & Furniture (3821)
- akta.pro primary industry
- Lab Safety, PPE & Contamination Control (Hoods, Biosafety Cabinets, Clean Air) (HLAGAIAK)
Keywords
Where ONFAB is headquartered
LocationHeadquarters
- HQ city
- Middlewich
- HQ country
- United Kingdom
- HQ region
- Europe
Offices3 records
Markets served
ONFAB business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Supply Chain, Operations, Technology or R&D, Marketing or Sales, Infrastructure
Revenue model
- Bespoke Flexible Isolator Systems: Custom-designed flexible containment isolators manufactured to customer specifications. Products include flexible process isolators, standalone isolators, ADC isolators, and specialized containment equipment. Revenue generated from equipment sales with typical installation time of 5-6 weeks from enquiry.
- Installation and Training Services: Complete installation services performed by ONFAB's own team (never sub-contracted) with full training on safe setup, usage, and decontamination. Installation Qualification (IQ) and Operational Qualification (OQ) available upon request.
- Service and Maintenance: Ongoing service and maintenance support for containment systems, including contact options for service enquiries.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Multi-year contract | Custom Bespoke Solutions |
Go-to-market motion2 records
Distribution channels3 records
Marketing channels6 records
ONFAB product offering
Product offeringCore offering
ONFAB designs and manufactures bespoke, single-use flexible containment isolators and accessories for pharmaceutical powder handling, HPAPI processing, and patient isolation. Its flexible-film isolator systems are engineered for OEB 4/5 containment across weighing, dispensing, milling, granulation, blending, encapsulation, coating, spray drying, centrifugation, reactor charging and ADC workflows, complemented by standalone accessories (Fan Sets, Venturi Air Ejectors, Pressure Alarms, CLASP Liner Tie Systems, Liner Cartridges) and installation, training and maintenance services.
Product overview
ONFAB is a provider of bespoke, single-use flexible pharmaceutical containment solutions for pharmaceutical process manufacturing. The product portfolio is organized into three main categories: Flexible Process Isolators (11 products including weighing & dispensing, milling, granulating, coating, and drying isolators), Flexible Standalone Isolators (10 products including standalone isolators, pop-up isolators, nitrogen isolators, and accessories like fan sets and pressure alarms), and ADC Isolators (1 product for antibody-drug conjugate manufacturing). Additional offerings include containment rooms, door enclosures, and accessories such as the CLASP liner tie system and liner cartridges. The products provide containment performance to OEB 4 and OEB 5 levels (typically below 30 ng/m3) and are designed to retrofit to existing pharmaceutical process equipment, reducing cleaning validation costs and downtime compared to rigid isolator systems.
Differentiator
Problem solved
Functional benefit
Products and services
- Flexible Weighing & Dispensing Isolator
- Milling & Compacting Isolator Single-use flexible containment isolator designed to contain pharmaceutical powder milling and compacting processes, protecting operators from exposure to potent APIs.
- Sizing Isolator Single-use flexible isolator for particle sizing of pharmaceutical powders under OEB 4/5 containment, used during drug substance and drug product processing.
- Drying Isolator Flexible containment isolator engineered to contain pharmaceutical drying processes while maintaining operator protection and product containment.
- Granulating & Blending Isolator Single-use flexible isolator providing OEB 4/5 containment for granulation and blending of pharmaceutical powders in oral solid dose manufacturing.
- Encapsulating & Compressing Isolator Flexible containment isolator designed for encapsulation and tablet compression operations, protecting operators from exposure during downstream oral solid dose manufacturing.
- Coating Isolator Single-use flexible isolator for tablet coating processes, providing containment of potent APIs and protecting operators during film-coating operations.
- API Synthesis Isolator Flexible containment isolator for API synthesis, providing high-level operator containment during chemical processing of active pharmaceutical ingredients.
- Reactor Charge Isolator Single-use flexible isolator for safe reactor charging with potent compounds, enabling contained transfer of APIs into reactor vessels without operator exposure.
- Spray Drying Isolator Flexible containment isolator designed to enclose spray drying equipment, providing OEB 4/5 containment during pharmaceutical spray drying processes.
- Centrifuge Isolator Single-use flexible isolator engineered to contain centrifuge operations involving potent pharmaceutical compounds, enabling contained solid-liquid separation.
- Standalone Isolator Freestanding single-use flexible containment isolator for general pharmaceutical containment applications where a dedicated process-specific isolator is not required.
- Pop-Up Isolator Disposable, rapidly deployable single-use flexible isolator designed for fast installation, short campaigns, and emergency containment capacity for pharmaceutical powders.
- Nitrogen Isolator Flexible containment isolator with nitrogen inerting capability for pharmaceutical processes that require oxygen- or moisture-controlled handling.
- ADC Isolator Flexible containment isolator engineered for handling antibody-drug conjugates (ADCs), providing high-level containment of highly potent cytotoxic payloads during processing.
- Containment Rooms & Door Enclosures Bespoke flexible containment rooms and door enclosures for controlled pharmaceutical manufacturing environments, providing larger-scale containment solutions beyond single isolators.
- Patient Isolation Dome Disposable patient isolation dome for healthcare use, providing sterile isolation environments for patients in hospital and clinical settings.
- Fan Set Standalone fan unit providing controlled airflow and negative pressure for ONFAB flexible containment isolators, sold as an accessory.
- Venturi Air Ejector Standalone Venturi-based air ejector accessory for ONFAB isolators, providing vacuum/air movement without electrical components for hazardous environments.
- Pressure Alarm Standalone pressure monitoring and alarm accessory for ONFAB isolators, providing real-time containment verification.
- CLASP Liner Tie System Proprietary liner-anchoring accessory that secures the disposable flexible liner to the isolator frame for safe drum discharging and contained transfers.
- Liner Cartridge Continuous-liner cartridge consumable for ONFAB isolators, enabling drum discharging without breaking containment.
- Installation & Training Services Professional installation, commissioning, and operator training services delivered by ONFAB engineers for flexible containment isolator systems at customer sites.
- Service & Maintenance After-sales service, maintenance, spare parts, and consumables supply for installed ONFAB isolator systems.
Quantifiable outcome
- Containment performance below 30 ng/m3 (OEB 4 and OEB 5 levels)
- +4 more outcomes
Companies that use ONFAB
Customer profileNamed customers9 records
Segments3 records
Ideal customer profiles3 records
ONFAB technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature7 records
ONFAB partnerships and signals
Strategic signalPartnerships
13 partnerships are on record, tiered minor and core.
- TCS (Industrial Fume Cupboard Specialist)minorAcquisition of TCS, an industrial fume cupboard specialist, enhanced Envair Technology's positioning as a global leader in contained clean air solutions.
- Liverpool University Hospitals NHS Foundation TrustminorPartnership with the Anaesthetic Department of Liverpool University Hospitals NHS Foundation Trust to develop the Patient Isolation Dome in response to the COVID-19 pandemic for healthcare worker protection during aerosol generating procedures.
- Envair LtdcoreONFAB acquired UK market leader in rigid isolators, Envair Ltd, in 2017, leading to the formation of parent company Envair Technology. This combined ONFAB's flexible containment with Envair's rigid isolator capabilities.
- Benchmark ProductsminorUSA-based distributor of ONFAB products located in Waukegan, Illinois.
- Tema Kozmetik Ilaç Makina San. Ve Tic. Ltd.minorTurkey-based distributor of ONFAB products located in Istanbul.
- Chinyee Technology LimitedminorChina-based distributor of ONFAB products located in Beijing.
- Automed Systems LtdminorIndia-based distributor of ONFAB products located in Bengaluru.
- naPHalminorGreece-based distributor of ONFAB products located in Athens.
- Pharmedley Pte LtdminorSingapore-based distributor of ONFAB products.
- Critical Scientific Solutions Pty Ltd (CSS)minorAustralia-based distributor of ONFAB products located in New South Wales.
- Jordan Technology Access (JoAccess)minorJordan-based distributor of ONFAB products located in Amman.
- Flotek SystemsminorIndia-based distributor of ONFAB products located in Vasai Estate.
- Keyen Enterprise, Co., Ltd.minorTaiwan-based distributor of ONFAB products located in Taipei.
Scale indicators10 records
Recent moves8 records
Expansion highlights6 records
ONFAB competitors and assessment
Company assessmentDirect peers
- Franz Ziel: German specialist in isolation technology for the pharmaceutical and chemical industries, with strong presence in Europe. Direct competitor to ONFAB in contained HPAPI handling and aseptic processing isolators.
- ILC Dover: US manufacturer of single-use flexible containment solutions for pharmaceutical powder handling. Closest direct US-headquartered competitor to ONFAB's flexible isolator approach and ADC containment.
- Dec Group: Swiss provider of contained material handling and isolation technology for pharmaceutical and chemical powder processes. Competes head-to-head with ONFAB in flexible and rigid containment for HPAPI manufacturing.
- Extract Technology: UK-based specialist in containment isolators and aseptic processing equipment for pharmaceutical manufacturers. Directly competes with ONFAB in flexible and rigid isolation for HPAPI handling and shares the same blue-chip pharma customer base.
- ChargePoint Technology (part of Steris): UK-based manufacturer of split butterfly valve containment and aseptic transfer solutions, now part of Steris. Direct competitor to ONFAB in contained powder transfer and HPAPI handling for pharmaceutical customers.
Emerging players
- Bioquell (Ecolab): Provider of bio-decontamination and containment solutions for life sciences, now part of Ecolab. Partial overlap with ONFAB in clean air and contamination control for pharmaceutical and healthcare environments, including the COVID-19 era overlap with the Patient Isolation Dome.
Broad incumbents
- Hosokawa Micron: Global supplier of powder and particle processing equipment, including containment solutions for pharmaceutical manufacturers. Overlaps with ONFAB in HPAPI handling and isolator integration for milling, drying, and blending processes.
- ATS Corporation / Comecer: Through its Comecer brand, ATS provides pharmaceutical isolators, containment, and aseptic processing equipment. Competes with ONFAB in sterile and potent compound containment for global pharma manufacturers.
- GEA Group (Pharma Containment): Large industrial processing group with a pharmaceutical containment portfolio including isolators and aseptic equipment. A broader incumbent competing with ONFAB in containment and integrated processing lines rather than a focused flexible-isolator specialist.
- Getinge (Pharma Isolators): Major medical and life-science equipment company offering isolators and barrier systems for pharmaceutical manufacturing. Competes with ONFAB at the larger pharma accounts through broader integrated processing solutions.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
ONFAB social profiles
Digital presenceONFAB compliance and trust
Trust signalCompliance1 record
ONFAB financial estimates
Financial estimateRevenue estimate
Valuation estimate
ONFAB leadership team
Management profileNumber of profiles
Profiles6 records
ONFAB funding detail
Funding detailFunding overview
Funding rounds1 record
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
ONFAB M&A and investment
M&A and investmentM&A1 record
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about ONFAB
What does ONFAB do?
ONFAB designs and manufactures bespoke, single-use flexible containment isolators and accessories for pharmaceutical powder handling, HPAPI processing, and patient isolation. Its flexible-film isolator systems are engineered for OEB 4/5 containment across weighing, dispensing, milling, granulation, blending, encapsulation, coating, spray drying, centrifugation, reactor charging and ADC workflows, complemented by standalone accessories (Fan Sets, Venturi Air Ejectors, Pressure Alarms, CLASP Liner Tie Systems, Liner Cartridges) and installation, training and maintenance services.
Is ONFAB a public or private company?
ONFAB is a private company. It is classified as corporate owned and is currently operating.
When was ONFAB founded?
ONFAB was founded in 2004. It employs 1 to 10 people.
Where is ONFAB based?
ONFAB is headquartered in Middlewich, United Kingdom, in the Europe region.
How does ONFAB make money?
Three revenue lines are on record. Bespoke Flexible Isolator Systems are the primary driver. The others are installation and Training Services and service and Maintenance.
Who are ONFAB's main competitors?
Direct peers on record are Franz Ziel, ILC Dover, Dec Group, Extract Technology and ChargePoint Technology (part of Steris). Bioquell (Ecolab) is listed as an emerging player. Broad incumbents are Hosokawa Micron, ATS Corporation / Comecer, GEA Group (Pharma Containment) and Getinge (Pharma Isolators).
Does ONFAB have an API?
No public API is recorded for ONFAB.
What industry is ONFAB in?
ONFAB's product category is Pharmaceutical containment equipment. Its primary akta.pro industry code is HLAGAIAK, Lab Safety, PPE & Contamination Control (Hoods, Biosafety Cabinets, Clean Air). Its NAICS code is 333413 and its SIC code is 3564.