Health Universe

What Health Universe does

Health Universe is a San Francisco-based enterprise AI platform for healthcare, founded in 2023 and venture-backed by Kleiner Perkins, Susa Ventures, Twelve Below, and Oncology Ventures with $9.5 million in total funding. The company provides a HIPAA-compliant, ONC B.11-certified platform that enables healthcare organizations to deploy, manage, and monitor AI agents over patient records within secure organizational workspaces. Its core product, Navigator, supports retrieval-augmented generation (RAG), custom agentic pipelines, and integration with EHRs via FHIR, HL7, and CCDA standards, augmented by an ecosystem of over 500 validated AI/ML applications.

The platform is architected around three primary workspaces: Navigator for secure conversational AI over patient records, Explorer for population-level cohort building, and Observer for hallucination detection and cost monitoring. Specialized vertical products include Oncology Agents that transform fragmented medical records into structured source-linked summaries, and Clinical Trials Agents that convert study synopses into comprehensive protocols, with a flagship deployment at Duke Clinical Research Institute demonstrating 30-40x acceleration in clinical trial setup. The platform supports multimodal inputs spanning text, structured clinical data, CT imaging, histology slides, lab work, and molecular reports for oncology decision support.

Health Universe operates a hybrid go-to-market combining product-led growth through a Free plan, Pro plan ($7/month), and Team plan ($25/seat/month) for individual clinicians and small teams, with an enterprise sales motion for health systems, academic medical centers, oncology practices, and EHR vendors. Enterprise contracts are quote-based and include white-glove support, custom onboarding, and additional hosting and compute fees. The company also generates revenue through implementation fees, expert services for application development and compliance consulting, and additional compute fees for high-volume processing. Named enterprise customers include Memorial Sloan Kettering Cancer Center, Duke Clinical Research Institute, New York Cancer & Blood Specialists, and academic institutions including Harvard, Stanford, UCSF, Carnegie Mellon, University of Washington, and Northeastern University.

Name

Health Universe

Legal name

Health Universe, Inc.

Website

https://healthuniverse.com

Company type

Private

Founded year

2023

Operating status

Operating

Headcount range

11–50 employees

Short description

Health Universe is a HIPAA-compliant, ONC B.11-certified AI platform that enables healthcare organizations to deploy, manage, and monitor AI agents over patient records. It serves health systems, academic medical centers, oncology practices, and EHR vendors through Navigator, Explorer, and a 500+ app ecosystem.

Ownership category

akta.pro rank

Product category

Healthcare AI Workflow Platform

NAICS

Computer Systems Design Services (541512), Custom Computer Programming Services (541511), Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (51821)

SIC

Services-Prepackaged Software (7372), Services-Computer Programming, Data Processing, Etc. (7370)

akta.pro primary industry

Care Management & Coordination Platforms (case/disease management workflows) (HLACAHAD)

akta.pro secondary industries

Data Aggregation, Interoperability & APIs for RPM (FHIR/IoMT Gateways) (HLACAFAO), Patient Engagement, Education & Messaging Platforms (portal/CRM integrated) (HLALABAJ), Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM), Oncology Remote Symptom Monitoring & Care Navigation (HLALAFAD)

Keywords

• Healthcare AI platform
• Clinical workflow automation
• HIPAA compliant AI
• AI agent deployment
• Clinical trial automation

Headquarters

HQ city

San Francisco

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Infrastructure, Marketing or Sales, Operations

Revenue model

1. SaaS Platform Subscriptions: Tiered subscription model (Free, Pro, Team, Enterprise) billed monthly or annually. Free and Pro plans target individual clinicians; Team targets small research organizations; Enterprise targets healthcare systems and academic medical centers. Enterprise pricing is quote-based with white-glove support included.
2. Implementation and Integration Fees: One-time implementation fees may apply for certain integrations, particularly for Enterprise customers requiring custom EHR connections or specialized deployment configurations.
3. Expert Services: Project-based engagements for application development, model refinement, compliance and security consulting, and deployment integration. Also includes ongoing support and maintenance packages and customized knowledge transfer/training programs.
4. Hosting and Compute Fees: Additional hosting and compute fees may apply beyond base subscription tiers, particularly for Enterprise customers with high-volume AI processing needs.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels8 records

Core offering

Health Universe provides a HIPAA-compliant, ONC B.11 certified AI workflow orchestration platform that enables healthcare organizations and clinicians to deploy, manage, and monitor AI agents over patient records. The platform's core product, Navigator, delivers a secure conversational AI workspace for clinical decision support, supported by Explorer (population-level analytics), Observer (hallucination and cost monitoring), and specialized Oncology and Clinical Trials agents. Customers include academic medical centers, oncology practices, and EHR vendors, with the platform processing over 170 million clinical documents and achieving 30-40x acceleration in clinical trial setup.

Product overview

Health Universe is an enterprise AI platform for healthcare workflows that provides a unified platform architecture with multiple integrated products and modules. The core offering is Navigator, a secure conversational AI workspace that serves as the organizational hub for deploying, managing, and monitoring AI agents. Supporting this are Explorer (population-level cohort building), Observer (agent monitoring for cost and hallucinations), and specialized Oncology Agents and Clinical Trials Agents for domain-specific automation. The platform includes a DSI (Decision Support Interventions) platform with a B.11 Compliance Wizard for ONC certification, along with Health Universe Missions for collaborative innovation and Expert Services for deployment support. The Agent-to-Agent (A2A) Marketplace is being built to enable cross-organization agent coordination.

Differentiator

Problem solved

Functional benefit

Brands

• Navigator: A secure organizational workspace for deploying, managing, and monitoring AI agents that run over patient records. Provides real-time, AI-powered insights directly within clinician workflows.
• Explorer
• Observer
• Project Loom

Products and services

• Navigator A secure conversational AI workspace for clinicians enabling real-time AI-powered insights directly within clinical workflows. Users can retrieve patient records from TEFCA, FHIR, or direct upload and run off-the-shelf agents, custom agents, or vendor-contributed agents over patient records. Provides evidence-based answers at the point of care.
• Explorer A population-level workspace for building patient cohorts and executing AI agents across defined populations. Enables healthcare organizations to run analytics at scale across patient populations.
• Observer Monitors AI agents for cost, hallucination detection, and high-risk scenario flagging with real-time alerts and audit trail recording. Enables governance and oversight of deployed AI agents in clinical environments.
• Oncology Agents Transforms fragmented medical records into structured, source-linked oncology summaries including diagnosis, staging, biomarkers, treatment history, and disease progression. Reduces hours of chart review to minutes for oncology practices.
• Clinical Trials Agents A multi-agent system that converts brief study synopses into comprehensive 75-page clinical trial protocols, with automated ClinicalTrials.gov submissions and IRB workflow integration. Co-developed with Duke Clinical Research Institute.
• DSI (Decision Support Interventions) Platform ONC-certified platform for decision support interventions providing a wizard for DSI certification, supporting both evidence-based and predictive interventions. Version 1.0 certified on 11/13/2024 under modules 170.315 (b)(11), (g)(3,4,5).
• Health Universe Missions A platform connecting researchers to solve healthcare challenges through virtual hackathons and bounty programs, with awards starting at $5,000 for developing AI/ML applications.
• Expert Services Comprehensive project-based engagements including application development, model refinement, compliance and security guidance, and deployment and integration services with flexible engagement models.
• Agent-to-Agent (A2A) Marketplace A developing marketplace positioning Health Universe as the connective layer enabling healthcare AI agents to securely exchange documents and coordinate work across organizations.

Quantifiable outcome

• Clinical trial setup compressed from 6-9 months to approximately 7.5 days (30-40x acceleration) at Duke Clinical Research Institute
• +7 more outcomes

Named customers10 records

Segments6 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration3 records

AI capability9 records

Feature10 records

Partnerships

Six partnerships are on record, tiered core, flagship and minor.

• Kno2coreTechnology or Integration · 16 December 2025Health Universe and Kno2 partnered to provide instant medical record retrieval and AI-driven clinical insights to healthcare providers nationwide. The collaboration enables real-time access and transformation of patient records into actionable insights for clinics, hospitals, and health systems through Kno2's medical record retrieval network.
• Duke Clinical Research Institute (DCRI)flagshipStrategic or Co-development PartnerHealth Universe collaborated with Duke Clinical Research Institute to deploy autonomous AI agents (Project Loom) that reduced traditional clinical trial setup time from 9 months to approximately 7.5 days. DCRI serves as the flagship reference customer and co-development partner for Clinical Trials Agents. The partnership demonstrates 30-40x acceleration and 93% time savings across key workflow tasks.
• Yale Cancer CentercoreStrategic or Co-development PartnerDouglas Fridsma of Health Universe served as a keynote speaker at Yale Cancer Center's Precision Medicine in Cancer Program workshop on AI applications across the cancer care continuum, from clinical research to population health implementation. Demonstrates thought leadership positioning and academic collaboration.
• New York Cancer & Blood Specialists (NYCBS)coreStrategic or Co-development PartnerNYCBS partnered with Health Universe to accelerate AI initiatives and improve operational efficiencies. The oncology practice deployed Health Universe's Oncology Agents for structured medical record summaries and clinical trial matching. CEO Dr. Jeff Vacirca serves as a testimonial reference.
• Dr. Sarah Gebauer / ML for MDsminorStrategic or Co-development PartnerFounder of ML for MDs and Stanford anesthesiologist provides thought leadership endorsement of Health Universe. Represents clinical community influencer partnership for physician adoption.
• Memorial Sloan Kettering Cancer CenterminorStrategic or Co-development PartnerMitch Parker, affiliated with Memorial Sloan Kettering Cancer Center, provides a testimonial for Navigator: 'Navigator allows me to instantly analyze a patient and surface evidence based applications to deliver faster, better care.' Represents oncology customer reference.

Scale indicators10 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• OpenEvidence: AI-powered clinical decision support platform serving clinicians with synthesized medical evidence. Comparable to Health Universe's Navigator in targeting individual physicians with HIPAA-aware AI for point-of-care decision making, though OpenEvidence focuses on literature synthesis rather than agentic workflow orchestration.
• Atropos Health: Real-world evidence and clinical AI platform enabling providers to generate observational studies from EHR data. Comparable to Health Universe's Explorer and Clinical Trials Agents in applying AI to clinical research workflows and population-level analysis, with similar enterprise health system and AMC target customers.
• Tempus AI: AI-powered precision medicine platform with deep oncology focus, providing structured data, clinical trial matching, and decision support. Highly comparable to Health Universe's Oncology Agents in transforming fragmented oncology records into structured summaries and matching patients to trials, though at much greater scale and public-company maturity.
• DeepScribe: AI medical scribe and clinical documentation automation platform. Comparable to Health Universe's clinical documentation and Navigator workflows targeting clinician burnout reduction, with similar HIPAA-compliant, ambient AI approach though narrower in scope (documentation-only) and less emphasis on enterprise platform extensibility.
• Mendel: Clinical AI platform focused on structuring unstructured medical data and clinical trial matching. Directly comparable to Health Universe's Oncology Agents and Clinical Trials Agents in transforming medical records into structured clinical data and matching patients to relevant trials, serving similar enterprise oncology and research customers.

Emerging players

• Hippocratic AI: Healthcare-focused LLM company building safety-constrained generative AI for clinical and administrative workflows. Comparable to Health Universe in targeting clinician workflow automation with safety-first LLM deployment, though focused on dedicated model training rather than agent orchestration over existing foundation models.

Broad incumbents

• Microsoft (Azure Health Data Services / DAX Copilot): Hyperscaler offering healthcare-specific AI infrastructure (Azure Health Data Services, DAX Copilot, Nuance). Comparable to Health Universe's positioning as the AI infrastructure layer for healthcare, but with vastly greater scale, integrated EHR partnerships, and bundled enterprise sales motion.
• Google Cloud (Vertex AI for Healthcare / MedLM): Hyperscaler offering healthcare-tuned foundation models (MedLM) and FHIR-based data services on Google Cloud. Comparable to Health Universe in providing ONC-aligned, HIPAA-eligible AI infrastructure, with much deeper resources and bundled compute, but Health Universe differentiates via its app ecosystem and trial orchestration layer.
• Epic Systems: Dominant EHR vendor embedding AI capabilities (including Cosmos, generative AI scribes) directly into clinician workflows. Comparable as ONC-certified healthcare AI infrastructure serving large health systems, but Epic controls the underlying patient data and clinician entry point that Health Universe must integrate with.
• AWS (HealthLake + Bedrock): Cloud platform offering HealthLake (HIPAA-eligible FHIR data store) and Bedrock foundation models. Comparable to Health Universe as AI infrastructure for healthcare data interoperability, with massively greater scale, though lacking Health Universe's specialized agentic workflows and B.11 attestation tooling.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/healthuniverse_
• LinkedInlinkedin.com/company/healthuniverse

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds3 records

Investors5 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Health Universe