Kno2
Kno2 operates the nation's largest healthcare communication network, delivering a single API and the Kno2fy portal that enable providers, payers, EHR vendors, and technology platforms to exchange patient information across TEFCA, Carequality, Direct, FHIR, HL7, and fax frameworks.
- Company typePrivate
- Founded2012
- HeadquartersBoise, United States
- Headcount11–50
- GTM typeB2B
- OfferingSoftware
What Kno2 does
Kno2 operates a healthcare communication network that delivers clinical information exchange across the U.S. healthcare ecosystem through a single API and an adjacent web-based portal (Kno2fy). The company's core product is the Kno2 Communication API, a REST-based interface providing Send, Receive, and Find routes that normalize access to fax, Direct Secure Messaging, FHIR, HL7 V2.x, Carequality, TEFCA via its QHIN designation, and 20+ HIEs. Complementing the API is the Kno2fy Portal, a HIPAA-compliant web interface consolidating cloud fax, Direct messaging, EHR integration, referral workflows, and e-signature into a single subscription. Feature surface also includes Track the Fax barcode reconciliation, the content-agnostic FHIR model, the provider communication directory, the CAREplan clinical communication workflow product, and the recently announced CLEAR1 core network infrastructure rollout (January 2026).
Kno2 serves four primary customer segments: healthcare providers (acute, post-acute, home health, behavioral health, specialty practices), technology vendors (EHRs, digital health platforms, RPM companies), payers (the first being Clover Health live on a CMS Aligned Network and TEFCA in March 2026), and value-based care organizations. Distribution combines direct enterprise sales, a self-service developer portal, a Connected Partner Program (EHRs, RPM, digital health, office technology OEMs such as Konica Minolta and Xerox), and a strategic alliance with Redox that together reach nearly 160,000 provider organizations representing 75% of U.S. health systems. Notable enterprise logos include PointClickCare, The Pennant Group, Symphony Care Network, Carilion Clinic, and Zus Health, alongside EHR integrations with Epic, Oracle Health, and CommonWell. Compliance posture includes HITRUST r2 certification on the Kno2fy Platform and SOC 2 Type II certification.
Revenue is generated primarily through recurring API subscriptions to the communication network and Kno2fy portal subscriptions, with enterprise add-ons (SSO, bulk uploads, enterprise APIs, private label, volume tools). Pricing is quote-based and not publicly disclosed; the company positions its "connect once" economic model against the alternative of building separate integrations to each network. The firm is privately held (Idaho LLC, Boise HQ with a Scottsdale office), backed by HEP and Providence Ventures following a $15 million Series A in 2023, and employs 11–50 people. Founded in Boise in 2012, Kno2 has expanded from document exchange to a federally designated QHIN under TEFCA and a pledged CMS Aligned Network.
Kno2 firmographics
Firmographics- Name
- Kno2
- Legal name
- Kno2 LLC
- Website
- https://kno2.com
- Company type
- Private
- Founded year
- 2012
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Kno2 operates the nation's largest healthcare communication network, delivering a single API and the Kno2fy portal that enable providers, payers, EHR vendors, and technology platforms to exchange patient information across TEFCA, Carequality, Direct, FHIR, HL7, and fax frameworks.
- Ownership category
- akta.pro rank
Kno2 industry classification
Industry- Product category
- Healthcare Interoperability Platform
- NAICS
- Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (518), Computer Systems Design and Related Services (54151)
- akta.pro primary industry
- Remote Patient Monitoring (RPM) Platforms & Device Hubs (Connectivity/Gateways) (HLAHACAH)
Keywords
Where Kno2 is headquartered
LocationHeadquarters
- HQ city
- Boise
- HQ country
- United States
- HQ region
- North America
Offices2 records
Markets served
Kno2 business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Technology or R&D, Personnel, Marketing or Sales, Operations, Infrastructure
Revenue model
- Communication API Subscription: Kno2 generates revenue through API subscription fees where technology vendors, EHRs, and healthcare organizations pay for access to the communication network. The company states it offers disruptive, affordable economics where partners pay for one connection but gain access to all networks and interoperability frameworks. Pricing is provided as a single connection point to the combined network's full reach.
- Kno2fy Portal Subscription: The Kno2fy web-based portal is offered as a single subscription model that centralizes all patient information sharing and communications. This includes cloud faxing, Direct messaging, EHR integration, referral workflows, and other communication capabilities.
- Enterprise Features: Large enterprise customers can access additional features including single sign-on, bulk uploads, Enterprise APIs, private label options, volume-based file handling tools, and centralized shared service functions.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Annual | Single API subscription with comprehensive access |
Go-to-market motion1 record
Distribution channels5 records
Marketing channels8 records
Kno2 product offering
Product offeringCore offering
Kno2 develops and operates a full-stack healthcare communication network that provides a single Communication API and the Kno2fy Portal for clinical information exchange. The platform enables healthcare providers, payers, EHRs, and health IT companies to send, receive, and find patient information across fax, Direct Secure Messaging, FHIR, HL7 V2.x, Carequality, and TEFCA/QHIN networks through one integration.
Product overview
Kno2 is a full-stack healthcare communication network providing a unified platform for clinical information exchange across the healthcare ecosystem. The core offering consists of two access methods: the Kno2 Communication API (for technology vendors and organizations requiring programmatic integration) and the Kno2fy Communication Portal (for organizations needing web-based access). These are supported by multiple connectivity features including Carequality network integration, cloud fax, Direct Secure Messaging, electronic signing, HIE connectivity, HL7 FHIR, HL7 V2.x, referral networks with 360X protocol, and TEFCA/QHIN services. The platform processes billions of transactions annually, connecting over 100,000 provider organizations across acute, post-acute, and specialty care settings.
Differentiator
Problem solved
Functional benefit
Brands
- Kno2fy: Kno2's turnkey, web-based HIPAA-compliant communication portal that centralizes and manages all major forms of patient information sharing and communications in a single subscription.
Products and services
- Kno2 Communication API A REST-based Communication API that enables technology vendors, EHRs, payers, and healthcare organizations to send, receive, and find clinical information across the entire healthcare ecosystem through a single integration to TEFCA, Carequality, Direct Secure Messaging, FHIR, HL7 V2.x, cloud fax, and HIE networks.
- Kno2fy Communication Portal A turnkey, web-based HIPAA-compliant communication portal that centralizes and manages all major forms of patient information sharing including cloud faxing, Direct messaging, EHR integration, provider directories, auditing, reporting, and customizable referral workflows in a single subscription.
- QHIN Services (TEFCA) Qualified Health Information Network services under TEFCA enabling nationwide health information exchange, including access to federal health information networks and CMS Aligned Network capabilities. QHIN services are integrated into the Communication API and can be white-labeled for partners.
Quantifiable outcome
- Multi-million dollar ROI for healthcare systems modernizing electronic faxing workflows
- +2 more outcomes
Companies that use Kno2
Customer profileNamed customers10 records
Segments4 records
Ideal customer profiles4 records
Kno2 technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- Yes
- API docs
- API detail
Core technology
AI maturity
App detail
Integration6 records
Feature10 records
Kno2 partnerships and signals
Strategic signalPartnerships
21 partnerships are on record, tiered flagship, core and standard.
- CareQuest Innovation PartnersflagshipStrategic partnership to integrate dental care into the nation's health information exchange infrastructure. Two leading electronic dental record platforms representing approximately 20% of the dental market have committed as flagship partners. Goal is production go-live within six months and 25% adoption among participating EDR provider users in the first year. Enables bidirectional data exchange between medical and dental providers for improved care coordination, patient safety, and health equity.
- Clover HealthcoreClover Health became the first payer to go live on a CMS Aligned Network and TEFCA through collaboration with Kno2. Enables real-time patient access to claims and clinical data using standardized FHIR (USCDI v3) formats. Powered by Counterpart Health's infrastructure, allowing patients to securely authenticate and request health information from any participating payer through Kno2's connected network.
- OliostandardBehavioral health coordination company Olio partnered with Kno2 to integrate real-time EHR access into its platform, streamlining care coordination for patients moving between healthcare settings.
- FlexpastandardPartnership combines patient-authorized data aggregation with Kno2's nationwide QHIN infrastructure to improve care coordination. Patients can more easily access and share their health data across the healthcare ecosystem.
- RXNTcoreRXNT announced TEFCA connectivity and integrated QHIN access through strategic partnership with Kno2. The integration connects RXNT's customers to over 10,000 organizations with planned availability in 2026. Enables nationwide interoperability for healthcare data exchange.
- Greenlight Health Data SolutionscoreExpanded partnership with Kno2 to enhance national healthcare data interoperability through TEFCA. Collaboration aims to support secure, patient-mediated health data exchange and expand TEFCA-enabled connectivity in the healthcare industry.
- Health UniversestandardPartnership to provide instant medical record retrieval and AI-driven clinical insights to healthcare providers nationwide. Collaboration enables real-time access and transformation of patient records into actionable insights for clinics, hospitals, and health systems.
- Net HealthcoreExpanded strategic partnership with Net Health (active since 2021) to enhance healthcare data exchange capabilities across various care settings. Partnership aims to improve interoperability, reduce reliance on fax workflows, and support compliance with federal regulations.
- RedoxflagshipStrategic alliance to transform healthcare data exchange nationwide. Combined network transacts over 40 billion annual transactions and connects nearly 160,000 provider organizations representing 75% of health systems and 80% of providers from non-acute settings. The partnership provides unified integration through a single connection point with scalable architecture for bi-directional data flow and universal data translation to HL7v2, FHIR, X12, CDA, and proprietary formats.
- NextGen HealthcarecorePartnership to advance interoperability for healthcare organizations across the US. Integration enables more than 100,000 providers representing a wide range of specialties to participate in TEFCA through NextGen's partnership with Kno2. Positions both companies to expand reach within the healthcare IT ecosystem while enabling frictionless, secure data flow across providers, payers, and patients.
- Zus HealthcoreZus Health partnership making Kno2 their official QHIN partner to enhance healthcare data exchange and interoperability. Collaboration aims to improve health data sharing, patient outcomes, and support implementation of TEFCA frameworks. Kno2's APIs provide configurability and performance needed for Carequality and TEFCA connectivity.
- EpiccoreEpic is listed as a participant in Kno2's network ecosystem, enabling data exchange through Carequality and interoperability frameworks.
- Oracle HealthcoreOracle Health is listed as a participant in CMS interoperability initiatives and Kno2's network ecosystem.
- CommonWell Health AlliancecoreCommonWell is part of Kno2's national network connectivity, enabling health data exchange across member organizations.
- PointClickCarecoreSenior care EHR platform partnered with Kno2 for value-based care data exchange, increasing care coordination, closing gaps in care, and reducing readmission risks.
- DocuSigncoreDocuSign is integrated with Kno2 for electronic signing workflows, enabling documents to be delivered for signature to any Kno2 Connected platform or EHR.
- Konica MinoltastandardKonica Minolta devices are Kno2 Connected, enabling multi-function printers to integrate with Kno2's communication network.
- XeroxstandardXerox devices are Kno2 Connected, enabling office equipment to integrate with Kno2's healthcare communication network.
- WellSkycoreWellSky is a Kno2 Connected partner providing post-acute care technology solutions with interoperability capabilities.
- AxxesscoreAxxess is a Kno2 Connected partner for home health technology solutions.
- MuleSoft / SalesforcecoreKno2 offers a MuleSoft Connector enabling integration with Salesforce ecosystem and enterprise workflow automation.
Scale indicators8 records
Recent moves7 records
Expansion highlights9 records
Kno2 competitors and assessment
Company assessmentMarket position
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
Kno2 social profiles
Digital presenceKno2 compliance and trust
Trust signalCompliance2 records
Kno2 financial estimates
Financial estimateRevenue estimate
Valuation estimate
Kno2 leadership team
Management profileNumber of profiles
Profiles12 records
Kno2 funding detail
Funding detailFunding overview
Funding rounds3 records
Investors2 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Kno2 M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Kno2
What does Kno2 do?
Kno2 develops and operates a full-stack healthcare communication network that provides a single Communication API and the Kno2fy Portal for clinical information exchange. The platform enables healthcare providers, payers, EHRs, and health IT companies to send, receive, and find patient information across fax, Direct Secure Messaging, FHIR, HL7 V2.x, Carequality, and TEFCA/QHIN networks through one integration.
Is Kno2 a public or private company?
Kno2 is a private company. It is classified as venture growth investor backed and is currently operating.
When was Kno2 founded?
Kno2 was founded in 2012. It employs 11 to 50 people.
Where is Kno2 based?
Kno2 is headquartered in Boise, United States, in the North America region.
How does Kno2 make money?
Three revenue lines are on record. Communication API Subscription is the primary driver. The others are kno2fy Portal Subscription and enterprise Features.
Does Kno2 have an API?
Yes. Kno2 provides a REST-based Communication API that enables healthcare organizations to send, receive, and find patient information across the healthcare ecosystem. The API provides single integration access to the Kno2 network, supporting communication across fax, Direct Secure Messaging, FHIR, HL7 V2, and national networks including Carequality and TEFCA/QHIN. Through Send, Receive, and Find routes, partners can communicate across all channels and networks without building to each connection type individually. Developer portal available at developer.kno2.com with documentation for rapid integration. Developer documentation is at developer.kno2.com/kno2.
What industry is Kno2 in?
Kno2's product category is Healthcare Interoperability Platform. Its primary akta.pro industry code is HLAHACAH, Remote Patient Monitoring (RPM) Platforms & Device Hubs (Connectivity/Gateways). Its NAICS code is 518.