Enzymedica

What Enzymedica does

Enzymedica is a US-based, privately held digestive health and wellness supplement company founded in 1998 and headquartered in a LEED Gold-certified facility in Venice, Florida. The company develops, manufactures, and distributes a portfolio of more than 50 enzyme-based, probiotic, and adjacent wellness SKUs under the Enzymedica master brand and the SubCulture™ probiotic sub-brand. Its core product platform is built on proprietary technologies including Thera-blend® (multi-strain enzyme blending across pH levels), ATPro™ (food-to-fuel energy conversion), Phytosome® (phospholipid-based nutrient delivery for ingredients such as berberine, PEA, and lemon balm), and SubCulture™ Probiotics (clinically studied multi-strain formulations). Flagship SKU Digest Gold® with ATPro® carries approximately 25 industry awards and is positioned as the company's #1 product; the broader portfolio addresses digestive support, food intolerances (lactose, gluten, dairy), regularity, immune support, metabolic health, sleep/stress, joint/muscle comfort, and seasonal wellness, with the most recent addition being Fasting Today, an intermittent fasting drink mix launched in May 2024. The company operates a B2C-only commercial model — there are no enterprise customers or B2B contracts of meaningful scale — selling through its own DTC e-commerce storefront (enzymedica.com) with a Subscribe & Save subscription program, alongside broad retail distribution through Whole Foods, Vitamin Shoppe, Kroger, Amazon, iHerb, Vitacost, Swanson, Pure Formulas, and additional specialty and international distributors, plus a parallel practitioner channel at enzymescience.com. Customer segments are health-conscious consumers, food-intolerance sufferers, gut-health seekers, immune-health buyers, and active-lifestyle/mobility users, addressed via content marketing, social channels (Instagram, TikTok, YouTube, X/Facebook), email, an interactive digestive enzyme quiz, and an affiliate program. Pricing spans roughly $10–$87 per SKU with both one-time purchase and recurring subscription billing options. Ownership appears founder-controlled, led by President & CEO Scott Sensenbrenner, with a senior leadership team covering sales (natural retail), eCommerce, education, scientific/regulatory affairs, and enzyme science.

Name

Enzymedica

Legal name

Enzymedica

Website

https://enzymedica.com

Company type

Private

Founded year

1998

Operating status

Operating

Headcount range

51–100 employees

Short description

Enzymedica is a US-based, founder-controlled digestive health supplement company founded in 1998, selling enzyme, probiotic, and adjacent wellness SKUs via DTC e-commerce, major US retail chains, and international distributors to health-conscious consumers.

Ownership category

akta.pro rank

Product category

Dietary Supplements (Digestive Health)

NAICS

Food (Health) Supplement Retailers (456191)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Probiotics & Digestive Health Supplements (CRADAGAF)

akta.pro secondary industries

Probiotics (Human & Animal Strains, Spore-Formers, Synbiotic Bases) (AFAJAJAE), Cultures, Probiotics & Fermentation Ingredients (Starter Cultures, Yeast, Adjuncts) (CRADAOAI)

Keywords

• Digestive enzyme supplements
• Probiotic supplements
• Dietary supplements
• Gut health products
• Natural wellness supplements

Headquarters

HQ city

Venice

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Marketing or Sales, Operations, Personnel, Technology or R&D

Revenue model

1. Direct Product Sales: Enzymedica generates revenue through direct-to-consumer sales via their e-commerce platform and retail distribution partnerships. Products are sold in various sizes (21-240 capsules) with price points ranging from approximately $10 to $87, supporting different customer purchase frequencies and budgets.
2. Subscription (Subscribe & Save): The Subscribe & Save program offers automatic deliveries with savings on regular orders. Benefits include free enrollment, customizable delivery frequency and quantity, and the flexibility to change or cancel subscriptions anytime.

Pricing tiers

Go-to-market motion1 record

Distribution channels8 records

Marketing channels8 records

Core offering

Enzymedica manufactures and sells a portfolio of enzyme-based and probiotic dietary supplements focused on digestive health, food intolerance management, gut wellness, and adjacent condition-specific categories (heartburn, immunity, sleep, joint, metabolism). Products are sold through the company's own e-commerce site with a Subscribe & Save subscription program and through major natural, grocery, and online retailers in the U.S. and internationally.

Product overview

Enzymedica is a digestive health and wellness supplement company offering a comprehensive portfolio of enzyme-based and probiotic products. The core portfolio centers on digestive enzyme supplements including flagship products like Digest Gold® with ATPro® (their #1 selling digestive enzyme), Digest Spectrum® for food intolerances, and Digest Complete® for everyday support. These are complemented by specialized enzyme products for dairy (Lacto®, DairyAssist®), gluten (GlutenEase®), fat (Lypo Gold®), vegetables (VeggieGest®), and beans (BeanAssist®). The company has expanded into adjacent wellness categories including the SubCulture™ probiotic line (for daily gut health, women, bloat, and mood), fiber supplements (Let's Go Fiber+), colostrum products, metabolic support (Berberine and Berberine Phytosome®), Phytosome®-enhanced supplements for joint/muscle (Joint & Muscle PEA Phytosome®) and sleep/stress (Sleep & Stress Lemon Balm Phytosome®), immune support, respiratory wellness, and systemic enzymes. The portfolio also includes Apple Cider Vinegar products, heart health supplements (Aqua Biome fish oils), and specialty products like Stem XCell and Telomere Plus for healthy aging. Key technology differentiators include Thera-blend® enzyme technology for multi-strain enzyme blends and Phytosome® delivery technology for enhanced nutrient absorption.

Differentiator

Problem solved

Functional benefit

Brands

• SubCulture™ Probiotics: Daily and specialty probiotic formulas made to support digestive balance, gut health, and whole-body wellness with scientifically studied strains for different wellness goals including regularity, mood, and women's health.

Products and services

• Digest Gold® with ATPro® Award-winning digestive enzyme supplement using Thera-blend® technology and ATPro® to break down carbs, fats, fiber, protein, and lactose while converting food to fuel for energy. Targeted at adults seeking digestive comfort and post-meal energy.
• Digest Spectrum® Specialized digestive enzyme formula designed to support breakdown of common problem ingredients for individuals with multiple food intolerances.
• Digest Complete® Daily digestive enzyme formula for everyday digestive support, available in capsule and chewable formats.
• Lypo Gold® Fat-digesting enzyme supplement with lipase formulated to support keto and low-carb dietary routines.
• Lacto® Dairy-digesting enzyme supplement formulated specifically to break down lactose for lactose-intolerant consumers.
• GlutenEase® Enzyme supplement containing DPP-IV enzymes to break down gluten and casein, targeted at gluten-sensitive consumers.
• DairyAssist® Dairy-digesting enzyme supplement available in regular and chewable formats for lactose intolerance support.
• Berberine Phytosome® Metabolic support supplement using Phytosome® technology for enhanced berberine absorption, supporting blood sugar metabolism.
• Berberine Standard berberine supplement supporting metabolic function and blood sugar balance.
• Heartburn Soothe Chewable Fast-acting chewable formula combining alginate, prickly pear extract, and buffering agents for occasional heartburn relief.
• Acid Soothe® Natural occasional heartburn support combining alginate, DGL, and zinc carnosine.
• SubCulture™ Daily Gut Health Probiotic Daily probiotic delivering 30 billion CFU of 7 strains to support digestion, immunity, and regularity.
• SubCulture™ Probiotic for Women Targeted probiotic with clinically studied strains supporting urinary, vaginal, digestive, and immune health for women.
• SubCulture™ Probiotic for Bloat Probiotic blend with clinically studied strains to reduce occasional gas and bloating.
• SubCulture™ Probiotic for Mood Probiotic and post-biotic formula combined with L-Theanine to support mental stress and sleep quality.
• SubCulture™ Berry Blast Sugar-Free Probiotic Drink Mix Sugar-free on-the-go probiotic drink mix stick pack with 50 billion CFU of 7 strains in Berry Blast flavor.
• SubCulture™ Peach Bliss Sugar-Free Probiotic Drink Mix Sugar-free on-the-go probiotic drink mix stick pack with 50 billion CFU of 7 strains in Peach Bliss flavor.
• SubCulture™ Dinner Duo Convenience packs combining SubCulture™ probiotics and enzymes for targeted needs including Regularity, Gas & Bloating, and Dairy Control.
• Let's Go Fiber+ Fiber supplement combining prebiotics, probiotics, postbiotics, and resistant starch for gut health and regularity, available in Tropical and Strawberry Kiwi flavors.
• Colostrum + Probiotics Daily gut and immune health formula providing 2g colostrum and 10 billion CFU probiotics per scoop, sourced from grass-fed cows.
• Fasting Today® Intermittent fasting drink mix combining artichoke extract with natural ingredients to support hydration, reduce hunger, and promote muscle health during fasting windows.
• Apple Cider Vinegar Apple cider vinegar supplement in capsule form offered as an alternative to liquid ACV shots.
• Apple Cider Vinegar Gummies Gummy delivery format of the apple cider vinegar supplement.
• Immune Defense Regular Strength Immune support supplement formulated for everyday immune system function.
• Immune Defense Extra Strength Higher-potency immune support supplement for more intensive use.
• Vitamin D3 + Vitamin K2 Vegan vitamin D3 combined with K2 to support immune and bone health.
• MucoStop® Non-drowsy respiratory support supplement for seasonal and overall wellness.
• Allerase® Allergy enzyme supplement providing respiratory and sinus support.
• Joint & Muscle PEA Phytosome® Joint and muscle comfort supplement using Phytosome® technology for enhanced PEA absorption.
• Sleep & Stress Lemon Balm Phytosome® Melatonin-free sleep and stress support supplement using Phytosome® technology for enhanced lemon balm absorption.
• Magnesium Mind Magnesium-based supplement supporting brain health and calm.
• Magnesium Motion Magnesium supplement supporting muscle and joint comfort for everyday mobility.
• SerraGold® Systemic enzyme supplement with serrapeptase supporting whole-body wellness and recovery.
• Repair Gold® Systemic enzyme supplement supporting muscle and joint repair.
• Natto K® Systemic enzyme supplement with nattokinase supporting circulatory and cardiovascular health.
• Candidase® Enzyme supplement supporting balanced yeast levels and cleanse routines.
• Gut Motility Digestive support supplement with ProDigest® supporting gut motility and regularity.
• Kiwi Regularity Fiber chewable supplement with kiwi extract supporting regularity and digestive comfort.
• Aqua Biome Maximum Strength Maximum strength fish oil supplement with high EPA/DHA levels supporting cardiovascular and heart health.
• Stem XCell® Stem cell support supplement for healthy aging and cellular wellness.
• Telomere Plus® Healthy aging supplement supporting telomerase activity and cellular health.
• Papaya Gold Papaya-based digestive enzyme supplement for everyday digestive support.
• VeggieGest®

Quantifiable outcome

• 92% reduction in mock recall response time

Named customers1 record

Segments5 records

Ideal customer profiles5 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Eight partnerships are on record, tiered core and minor.

• Vitamin AngelscoreOthersVitamin Angels brings vitamins to over 52 million mothers and children at risk for malnutrition—reducing illness, blindness and death. Enzymedica supports this cause as part of their people and planet initiatives.
• Mote Marine Laboratory & AquariumcoreStrategic or Co-development PartnerEnzymedica partners with Mote Marine Laboratory to rebuild Florida Great Barrier Reefs using microfragmentation technology. Located near their headquarters, this partnership supports ocean conservation.
• Autism Hope AlliancecoreStrategic or Co-development PartnerFounded by Enzymedica, Autism Hope Alliance helps families of children with autism who often have food intolerances that enzymes can help address.
• Green Mountain EnergyminorStrategic or Co-development PartnerEnzymedica is a 100% carbon-neutral organization through partnership with Green Mountain Energy to offset carbon emissions from operations.
• Safe Place and Rape Crisis CenterminorOthersEnzymedica supports this state-certified organization helping stop domestic and sexual violence in their local communities through fundraising.
• Beagle Freedom ProjectminorOthersEnzymedica supports BFP's mission to rescue animals from testing facilities after witnessing animal testing firsthand.
• Bless the ChildrenminorOthersEnzymedica supports this organization's efforts to uplift the most impoverished children of the world.
• American Foundation for Suicide Prevention (AFSP)minorOthersEnzymedica supports AFSP's mission to change mental health conversations, save lives, and bring hope to those affected by suicide, including a local chapter in Southwest Florida.

Scale indicators3 records

Recent moves6 records

Expansion highlights7 records

Direct peers

• NOW Foods: Large US-based supplement manufacturer with deep enzyme, probiotic, and wellness SKUs sold through the same health-food retail and online channels as Enzymedica. Closest direct comparable by category breadth and distribution.
• Garden of Life: Premium organic/clean-label supplement brand with digestive enzymes, probiotics, and gut-health SKUs in Whole Foods, Sprouts, Vitamin Shoppe, and online. Directly competes with Enzymedica on clean-label positioning.
• Thorne: Premium practitioner-grade supplement brand with digestive, metabolic, and probiotic lines sold DTC and through practitioners. Competes with Enzymedica's premium tier and Phytosome®-enhanced SKUs.
• Jarrow Formulas: Specialty supplement brand with strong probiotics (jarro-dophilus) and digestive enzyme lines sold through natural retail and online. Direct head-to-head competitor in core enzyme category.
• Doctor's Best: Science-positioned supplement brand with digestive enzymes and metabolic products (berberine) distributed through Amazon, Vitamin Shoppe, and natural retail. Direct overlap with Enzymedica's enzyme and Phytosome portfolios.
• Life Extension: DTC- and catalog-led supplement brand with digestive, immune, and healthy-aging lines including enzyme and probiotic products. Comparable in direct-to-consumer model and premium positioning.
• Pure Encapsulations: Practitioner-channel hypoallergenic supplement brand with digestive enzyme and probiotic SKUs. Competes for the same practitioner-recommended wellness dollars as Enzymedica's enzyme science story.
• Integrative Therapeutics: Practitioner-brand digestive enzyme and probiotic line sold through healthcare professionals. Comparable in category focus and scientific/clinical positioning.

Emerging players

• Ritual: DTC-native supplement brand expanding from vitamins into gut health and synbiotics. Competes for the same health-conscious millennial/Gen-X consumer Enzymedica targets, with a stronger digital-native brand engine.

Broad incumbents

• AG1 (Athletic Greens): High-growth DTC greens/supplement brand with heavy subscription model and overlapping gut-health messaging. Represents the emerging subscription-first benchmark that Enzymedica's Subscribe & Save competes against.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/enzymedica
• YouTubeyoutube.com/@EnzymedicaEnzymes
• Facebookfacebook.com/enzymedica
• Instagraminstagram.com/enzymedica
• TikToktiktok.com/@enzymedica?_kx=KlMb56n8uPiskb1b_ZmsAw.StFvHQ
• LinkedInlinkedin.com/company/enzymedica

Compliance6 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Enzymedica