What Synapxe does

Synapxe is Singapore's national HealthTech agency, incorporated as Synapxe Pte Ltd and operating as a subsidiary of the Ministry of Health Holdings (MOH Holdings). Originally established in 2008 as IHiS (Integrated Health Information Systems) and rebranded in 2023, the organisation is the statutory digital-health delivery arm for Singapore's public healthcare system, mandated to design, build, and operate the national digital health infrastructure across all public hospitals, specialty centres, polyclinics, and supporting institutions. Its customers are not commercial buyers but the public healthcare ecosystem itself: three healthcare clusters (SingHealth, National Healthcare Group, National University Health System), polyclinic networks, public acute hospitals, and ultimately the 5.9 million Singapore residents who access personal health data through HealthHub.

Synapxe's product portfolio is structured as a national platform-plus-modules stack. Core platforms include HealthHub (consumer-facing health portal), NEHR (National Electronic Health Record), NGEMR (Next-Generation EMR replacing ~90 legacy systems across 37 institutions), NHIPS (pharmacy management integrated with 20+ systems), NBS (national billing across 60+ institutions), H-Cloud (ISO 27001 / ISO 20000-1 certified healthcare-dedicated private cloud with 99.95% availability), and HEALIX (cloud analytics). On top of this stack sits a broad AI portfolio—ACE-AI, SELENA+, CAPE, CKD Model, Multiple Readmissions Predictive Model, ASAR, AimSG, and the Tandem GenAI platform—plus robotics and automation systems (CLMM, OPAS, MMM). Distribution is conducted via direct government-mandated deployment rather than commercial sales.

The business model is government-funded rather than commercially priced. Revenue is sourced from annual budget allocations through MOH Holdings, and Synapxe operates as a captive national infrastructure provider with no commercial customer pricing in the public domain. Partnerships with hyperscalers (AWS for HEALIX; Microsoft for GenAI and Cloud), academic institutions (NUS, NTU, AI Singapore), and cluster-level deployment partners serve as co-development and scaling channels rather than revenue diversification. As a state-owned entity under a single parent, Synapxe has effectively a single counterparty for its funding, which is its central commercial structural feature.

Name

Synapxe

Legal name

Synapxe Pte Ltd

Website

https://synapxe.sg

Company type

Private

Founded year

2008

Operating status

Operating

Headcount range

1,001–5,000 employees

Short description

Synapxe is Singapore's national HealthTech agency, wholly owned under MOH Holdings. It builds and operates national digital health platforms (NEHR, NGEMR, NHIPS, HealthHub, H-Cloud) plus AI and automation products for all public hospitals, polyclinics, and 5.9M+ Singapore residents, funded through government appropriations.

Ownership category

akta.pro rank

Product category

National Healthcare IT Infrastructure

NAICS

Health Care and Social Assistance (62), Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (5182)

SIC

Services-Health Services (8000), Services-Prepackaged Software (7372)

akta.pro primary industry

HIE Platforms & Network Services (Community/Regional/National) (HLACABAB)

akta.pro secondary industries

Virtual Nursing, Telemonitoring & Command Center Platforms (HLACAFAH), Data Aggregation, Interoperability & APIs for RPM (FHIR/IoMT Gateways) (HLACAFAO), Chronic Condition Management & Remote Monitoring (e.g., diabetes, HTN) (HLALADAD)

Keywords

• National health information systems
• Electronic medical records
• Healthcare cloud infrastructure
• AI clinical decision support
• Pharmacy automation systems

Headquarters

HQ city

Singapore

HQ country

Singapore

HQ region

Asia

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Infrastructure, Operations, Marketing or Sales

Revenue model

1. Government Funding: As Singapore's national HealthTech agency, Synapxe operates as a statutory board or government agency funded through annual government预算 allocations from the Ministry of Health. Revenue is derived from public funds rather than commercial revenue streams.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels5 records

Core offering

Synapxe is Singapore's national HealthTech agency that designs, builds, and operates the digital health infrastructure for the country's public healthcare sector. It delivers national-scale platforms including electronic health records (NEHR, NGEMR), pharmacy management (NHIPS), national billing (NBS), a dedicated healthcare cloud (H-Cloud), and AI-powered clinical tools (ACE-AI, SELENA+, CAPE, Tandem). Its products are deployed across all public hospitals, polyclinics, specialty centres, and nursing homes in Singapore, and reach residents through the HealthHub portal.

Product overview

Synapxe is Singapore's national HealthTech agency operating as a platform-plus-modules architecture with diverse HealthTech solutions spanning national digital health infrastructure, AI-powered clinical tools, and automation systems. Core national platforms include HealthHub (consumer-facing digital health portal), National Electronic Health Record (NEHR - national health data repository), NGEMR (unified EMR across two healthcare clusters), NHIPS (pharmacy management), and National Billing System. The AI portfolio includes ACE-AI for chronic disease risk prediction, SELENA+ for eye disease detection, CKD Model for kidney disease progression, CAPE for pneumonia severity prediction, ASAR for drug safety surveillance, and Tandem GenAI platform. Robotics solutions comprise CLMM (inpatient medication management), Multi-Dose Medication Management System, and OPAS (outpatient pharmacy automation). Supporting systems include C3 hospital operations management, COVID-19 Test Repository, Bed Management System, eHINTS analytics, GPConnect clinic management, and various telehealth platforms. The portfolio serves citizens, clinicians, and healthcare workers across Singapore's public healthcare ecosystem.

Differentiator

Problem solved

Functional benefit

Brands

• HealthHub: A one-stop digital health platform providing information on medical conditions and secure access to health records for Singapore residents.
• NEHR (National Electronic Health Record)
• NGEMR (Next Generation Electronic Medical Record)
• NHIPS (National Harmonised Integrated Pharmacy System)
• NBS (National Billing System)
• H-Cloud
• Tandem
• HEALIX

Products and services

• HealthHub A one-stop digital health platform providing Singapore residents with information on medical conditions, secure access to personal health records, appointment management, and e-Services across public healthcare institutions; integrates with NEHR and the National Billing System.
• National Electronic Health Record (NEHR) National repository that collects and stores patient health information across different healthcare providers, enabling healthcare professionals across Singapore to access consolidated records for safer, better coordinated care.
• National Harmonised Integrated Pharmacy System (NHIPS) Common pharmacy platform harmonizing medication dispensing and streamlining medication-related billing across public healthcare institutions; serves as central repository for medication information, integrated with over 20 systems.
• Next Generation Electronic Medical Record (NGEMR) Single unified electronic medical record harmonizing clinical processes across the National Healthcare Group and National University Health System; deployed in 37 healthcare institutions and replacing approximately 90 legacy systems.
• National Billing System (NBS) National charging and billing system providing a consistent finance and billing experience for patients and healthcare professionals across 60+ public healthcare institutions with a standardised billing format.
• H-Cloud Private cloud computing platform supporting all public hospitals, specialty centres, polyclinics, and nursing homes in Singapore; provides 99.95% infrastructure availability with active-active configuration across two data centres, and is ISO 27001 and ISO 20000-1 certified.
• COVID-19 Test Repository (CTR) One-stop repository aggregating COVID-19 test results from multiple public and private laboratories, with over 27 million test results processed; tightly integrated with 10 downstream systems.
• Command, Control and Communications (C3) AI-powered hospital operations system that coordinates patient flow, provides real-time monitoring through data and video feeds, and uses prescriptive analytics for resource planning and optimisation.
• Patient Risk Profile Portal (PRPP) Portal for COVID-19 related operations in the primary care setting that identifies patient risk levels, supports swab registration, facilitates vaccination, and integrates with MOH systems.
• Bed Management System Comprehensive capacity management suite managing all aspects of bed management from admission to discharge; provides real-time insights into bed information to enable healthcare teams to optimise capacity planning.
• Electronic Health Intelligence System (eHINTS) Digital platform integrating and analysing data from multiple healthcare transactional systems including Administration, Clinical, and Ancillary systems; uses advanced analytics and machine learning for clinical decision support.
• ACE-AI (Assisted Chronic Disease Explanation using AI) AI-powered clinical decision support digital assistant providing personalised risk profiles for diabetes and hyperlipidaemia within three years, supporting clinicians in chronic disease management by flagging high-risk patients for early intervention.
• AI Medical Imaging Platform (AimSG) Open, vendor-neutral platform for deploying AI models in radiology and medical imaging, providing a marketplace of AI solutions for chest X-ray analysis and other imaging modalities at public hospitals.
• ASAR (Active Surveillance System for Adverse Reactions) First nationwide application analysing structured healthcare data and unstructured clinical notes from all public acute hospitals to detect and validate drug and vaccine safety signals; pools over 2 million de-identified records daily.
• CAPE (Community Acquired Pneumonia and COVID-19 AI Predictive Engine) AI-enabled tool predicting pneumonia severity in COVID-19 and other patients based on chest X-ray images and electronic medical records; uses deep learning trained on 3,000+ CXR images with approximately 80% accuracy.
• Chronic Kidney Disease Model (CKD Model) AI-powered predictive tool estimating risk of CKD progression in diabetic patients within 5 years; analyses over 177 variables across diagnostic, sociodemographic, laboratory, and medication history categories; integrated into NEHR.
• HEALIX Cloud-based analytics platform providing a standardised, secure, scalable environment for public healthcare entities to conduct analytics projects and rapidly develop AI models; developed with AWS.
• Multiple Readmissions Predictive Model Machine learning model automatically identifying patients likely to be readmitted multiple times over the next year; uses over 1,000 indicators with 70% prediction accuracy; integrated with the Hospital to Home programme.
• SELENA+ (Singapore Eye Lesion Analyser) Deep-learning AI software detecting threatening eye conditions including diabetic retinopathy, glaucoma, and age-related macular degeneration from retinal photographs; reduces screening workload by up to 50%.
• Tandem GenAI Platform Secure Generative AI platform enabling public healthcare professionals to explore, experiment, test, and deploy GenAI applications at scale; includes Discovery (productivity tool), Test Drive (sandbox), and Live (deployment) services.
• Closed Loop Medication Management System (CLMM) Integration of automated and intelligent systems closing the inpatient medication management loop from prescription ordering to administration; enhances patient safety and reduces medication errors; deployed in 8 major hospitals.
• Multi-Dose Medication Management System (MMM) Medication packaging system dispensing patients' medication into single sachets with right dosage, date, and time; rolled out to 16 nursing homes, the Institute of Mental Health, and NHG Polyclinics; dispenses medicine 14 times faster than manual packing.
• Outpatient Pharmacy Automation System (OPAS) Intelligent software system orchestrating the entire prescription filling process by integrating seven robotics technologies; automates sorting, packing, assembling, and dispensing; won 13 local and international awards including the WITSA Global ICT Excellence Award.
• 1 Queue (1Q) Integrated queue system generating one slip with a single queue number for all service points and consolidating payment to one station at the end of the visit; reduces patient waiting time by an average of 15 minutes; implemented across SingHealth facilities.
• GPConnect Tier-1 Healthier SG compatible clinic management system and electronic medical record for general practitioners; supports patient registration, consultations, medicine dispensation, and billing; adopted by over 200 GP clinics and rated as a top Smart Clinic Management System.
• KKH U-PAL Chatbot Chatbot providing virtual paediatric advice for parents to better understand their children's conditions through natural language interaction at KK Women's and Children's Hospital.
• PILBOX Service allowing patients or caregivers to collect repeat prescription refills from automated secure lockers for added convenience.
• Healthcare Integrated Pipeline (HIP) DevSecOps platform automating software development for Singapore's public healthcare sector.
• Health Services Administrative Repository (HSAR) Administrative data sharing repository supporting multiple national programmes.
• HealthGuide@Home Agentic AI-powered digital assistant for Singapore's Healthier SG national preventive care programme; generates personalised dietary and exercise plans based on individual health profiles and goals.
• New Interoperability Standards Two new interoperability standards introduced by Synapxe to assist Singaporean health tech startups in developing digital health solutions and supporting ecosystem-wide interoperability.
• Video Consultation Platform National telehealth platform enabling video consultations between clinicians and patients across Singapore's public healthcare institutions.
• Remote Clinical Monitoring Telehealth platform enabling remote clinical monitoring of patients across public healthcare institutions in Singapore.

Named customers9 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability12 records

Feature10 records

Partnerships

Ten partnerships are on record, tiered core and flagship.

• MOH HoldingscoreStrategic or Co-development PartnerMOH Holdings is the holding company for Singapore's public healthcare sector and Synapxe's parent organization. Synapxe operates as the national HealthTech agency under MOH Holdings, coordinating digital health infrastructure across all public healthcare institutions.
• Amazon Web Services (AWS)coreTechnology or IntegrationAWS collaborates with Synapxe on the HEALIX platform for health data analytics. AWS provides cloud infrastructure enabling Synapxe to process and analyze national health data at scale.
• MicrosoftflagshipStrategic or Co-development PartnerSynapxe signed an MOU with Microsoft for Generative AI and Cloud innovation in healthcare. The partnership focuses on developing AI-powered healthcare solutions using Microsoft Azure cloud platform and AI technologies.
• AI SingaporecoreStrategic or Co-development PartnerAI Singapore runs the AI Grand Challenge with Synapxe, focusing on developing AI solutions for Singapore's healthcare sector. The partnership leverages national AI research capabilities for health technology innovation.
• National University of Singapore (NUS)coreStrategic or Co-development PartnerAcademic partnership for research and development of healthcare technology solutions, leveraging NUS's academic expertise and research capabilities.
• Nanyang Technological University (NTU)coreStrategic or Co-development PartnerAcademic partnership for healthcare technology research and development, utilizing NTU's engineering and AI research capabilities.
• National University Health System (NUHS)coreImplementation/ SI/ Consulting PartnerNUHS is a major healthcare cluster that partners with Synapxe for deployment and testing of national digital health systems, including AI clinical decision support tools.
• SingHealthcoreImplementation/ SI/ Consulting PartnerSingHealth is one of Singapore's largest public healthcare clusters, partnering with Synapxe for deployment of national EMR systems and digital health initiatives.
• National Healthcare Group (NHG)coreImplementation/ SI/ Consulting PartnerNHG is a major public healthcare cluster that collaborates with Synapxe on digital health infrastructure deployment and integration.
• Health Sciences Authority (HSA)coreStrategic or Co-development PartnerHSA partners with Synapxe on the ASAR (AI Scribe for Radiology) project, integrating regulatory oversight with digital health innovation.

Scale indicators4 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Oracle Health (Cerner): Provides enterprise EHR and health information exchange platforms (Cerner) widely used by hospitals and national health systems. Directly comparable to Synapxe's national EMR (NGEMR), HIE (NEHR), and cloud-based health data infrastructure.
• InterSystems: Operates HealthShare, a leading health information exchange and interoperability platform used for national/regional health records. Directly comparable to Synapxe's NEHR platform and HL7 FHIR-based interoperability work.
• Epic Systems: Privately-held US EHR giant operating the most widely deployed electronic medical record systems for large health systems, including integrated national-scale deployments. Directly comparable to Synapxe's NGEMR and NEHR work for large hospital networks and integrated delivery networks.
• MEDITECH: Provides EHR systems for community hospitals and integrated delivery networks with a focus on interoperability. Comparable to Synapxe's NGEMR deployment across 37 healthcare institutions and emphasis on harmonizing clinical workflows.
• Health Catalyst: Healthcare data and analytics platform providing population health management, clinical decision support, and AI-driven insights. Directly comparable to Synapxe's eHINTS, HEALIX, and predictive AI portfolio (ACE-AI, CKD Model, Multiple Readmissions).

Others

• Government Technology Agency (GovTech) Singapore: Singapore's lead government technology agency that builds cross-ministry digital infrastructure and platforms. Comparable as a sibling Singapore government technology entity that shares ecosystem, policy, and infrastructure context with Synapxe, though not a direct healthcare-IT competitor.

Emerging players

• Innovaccer: Healthcare data activation platform focused on HIE, population health management, and provider/patient engagement. Comparable to Synapxe's NEHR, GPConnect, and HealthHub citizen/physician engagement stack with FHIR-based interoperability.
• 1upHealth: FHIR-native health data interoperability platform enabling API-based aggregation and exchange of clinical data. Comparable to Synapxe's HL7 FHIR-based interoperability standards and award-winning FHIR implementations for health-tech startups.

Broad incumbents

• Optum (UnitedHealth Group): Major healthcare data, analytics, and clinical decision support provider within UnitedHealth, operating at population scale. Comparable to Synapxe in operating large-scale health data infrastructure, AI-driven clinical tools, and population health analytics.
• NHS England (NHS Digital / Transformation Directorate): Operates the UK's national digital health infrastructure (NHS Spine, NHS App, electronic patient records). Closest structural analog to Synapxe as a government-mandated national health-IT agency responsible for population-scale health data exchange and citizen-facing apps.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/@synapxe
• Facebookfacebook.com/synapxe
• LinkedInlinkedin.com/company/synapxe
• Instagraminstagram.com/synapxe.singapore
• TikToktiktok.com/@synapxe.sg

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Synapxe