Microbiome Labs

Name

Microbiome Labs

Legal name

Physicians Exclusive, LLC

Website

https://microbiomelabs.com

Company type

Private

Founded year

2014

Operating status

Operating

Headcount range

51–100 employees

Ownership category

akta.pro rank

Product category

Probiotic Supplements

NAICS

Biological Product (except Diagnostic) Manufacturing (325414), Medical Laboratories (621511), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

In Vitro & In Vivo Diagnostic Substances (2835), Pharmaceutical Preparations (2834), Services-Medical Laboratories (8071)

akta.pro primary industry

Microbiome Manufacturing, Formulation & Delivery Technologies (encapsulation, spores, oral delivery) (HLAAAFAJ)

akta.pro secondary industries

Microbiome Diagnostics & Biomarker Platforms (gut/skin/oral/vaginal) (HLAAAFAH), Microbiome Analytics, Sequencing & Bioinformatics Platforms (HLAAAFAI), Probiotics & Digestive Health Supplements (CRADAGAF)

Keywords

• Spore-based probiotics
• Microbiome diagnostics
• Functional supplements
• Gut health products
• Clinical probiotics

Headquarters

HQ city

Glenview

HQ country

United States

HQ region

North America

Offices4 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Marketing or Sales, Technology or R&D, Operations, Others

Revenue model

1. Probiotic and Supplement Sales: Revenue is generated from the sale of proprietary probiotic and microbiome-support supplement products across categories including Gastrointestinal Health, Women's Health, Immune Support, Cognitive Health, Metabolic Support, Skin Support, Digestive Support, and Pet Health. Products are sold through practitioner accounts and Direct2Patient programs.
2. BiomeFX Diagnostic Testing Kits: The company sells functional microbiome analysis test kits (Stool Kit, Vaginal Health Kit) to practitioners, who then use results to recommend supplement protocols, bundling diagnostics with therapeutic products.

Pricing tiers

Go-to-market motion3 records

Distribution channels3 records

Marketing channels5 records

Core offering

Microbiome Labs develops, manufactures, and distributes clinically validated spore-based probiotic supplements and microbiome diagnostic test kits primarily to licensed healthcare practitioners in the integrative, functional, and holistic medicine fields. Its flagship product, MegaSporeBiotic, contains proprietary Bacillus strains (HU36, HU58) that survive digestion and colonize the gut, while the BiomeFX diagnostic platform uses whole genome sequencing with AI-powered interpretation to enable personalized supplement recommendations. Products are sold through practitioner-only accounts and a Direct2Patient program serving thousands of clinicians and their patients.

Product overview

Microbiome Labs offers a comprehensive microbiome-centered health platform built around spore-based probiotics and functional microbiome analysis. The core portfolio centers on MegaSporeBiotic, the company's flagship 100% spore-based probiotic (launched 2013) which pioneered the spore-based probiotic category, available in capsule, 180-capsule, adult gummy, and kids gummy formats. The BiomeFX diagnostic line provides functional microbiome analysis through stool and vaginal health testing kits powered by whole genome sequencing with AI-driven interpretation via JONA AI integration. Gastrointestinal health products include MegaMucosa (mucosal support), MegaPre (precision prebiotic), RestorFlora, HU58, Gut-Brain Reset, and Total Gut Restoration kits. Women's health offerings encompass Vaginal Balance and Pregnancy Support with clinically studied probiotic formulations. Additional products span digestive support (DigestMate, MegaGuard, FODMATE), immune support (EpicDefense, Mega IgG2000, PyloGuard), cognitive health (Zenbiome SLEEP, Zenbiome COPE via gut-brain axis), metabolic support (MegaQuin K2+D3, Omega Ultra SPM, MegaQuinone), skin support (Serene Skin), and pet health (FidoSpore). The company operates as part of Novonesis Group and distributes through practitioners with a Direct2Patient model.

Differentiator

Problem solved

Functional benefit

Brands

• MegaSporeBiotic: The company's flagship 100% spore-based, broad-spectrum probiotic blend designed to maintain healthy gut barrier function. Contains Bacillus spores including Bacillus Licheniformis, Bacillus Indicus HU36, Bacillus Subtilis HU58, Bacillus Clausii, and Bacillus Coagulans.
• BiomeFX
• DigestMate
• Zenbiome
• SereneSkin
• FidoSpore
• Total Gut Restoration
• Direct2Patient

Products and services

• MegaSporeBiotic 100% spore-based, broad-spectrum probiotic containing 5 Bacillus strains (Licheniformis, Indicus HU36, Subtilis HU58, Clausii, Coagulans) shown to maintain healthy gut barrier function and recondition the gut microbiome; for licensed healthcare practitioners.
• MegaSporeBiotic 180 Capsules Larger 180-capsule variant of the flagship spore-based probiotic for maintaining healthy gut barrier function.
• MegaSporeBiotic Gummies for Adults 100% spore-based probiotic gummies containing four Bacillus strains (HU36, HU58, SC208, SC109) for adults seeking convenient daily gut microbiome support.
• MegaSporeBiotic Gummies for Kids Spore-based probiotic gummies for children ages 4+, containing four Bacillus strains in a kid-friendly format.
• BiomeFX Stool Kit At-home functional microbiome stool analysis powered by whole genome sequencing, delivering 99.9% specificity and 95.7%+ sensitivity with AI-powered interpretation via JONA AI integration.
• BiomeFX Vaginal Health Kit At-home vaginal microbiome analysis using whole genome sequencing to quantify beneficial Lactobacilli and disruptive organisms, providing actionable recommendations for vaginal ecosystem restoration.
• MegaMucosa 180 Capsules First complete mucosal support supplement formulated with dairy-free immunoglobulins and flavobiotic to support healthy mucosal barrier, microbial diversity, and short-chain fatty acid production.
• MegaMucosa Powder Powder form of the complete mucosal support supplement with immunoglobulins and flavobiotic for mucosal barrier and microbial diversity support.
• MegaPre 180 Capsules First Precision Prebiotic supplement made up of clinically tested, non-digestible oligosaccharides to promote microbial diversity.
• RestorFlora Probiotic supplement combining well-studied probiotic strains for gut recovery and maintaining healthy gut microbial composition.
• HU58 Single-strain probiotic with concentrated dose of Bacillus subtilis HU58 for targeted gut health support.
• Gut-Brain Reset Dual-action probiotic combination designed to support both digestive comfort and mood self-regulation via the gut-brain axis.
• Mega Mycobalance Formulated with undecylenic acid and bee propolis to support healthy yeast and fungal balance in the body.
• Total Gut Restoration Kit 1 Kit including MegaSpore 180 capsules, MegaPre capsules, and MegaMucosa capsules for comprehensive gut restoration protocol.
• Total Gut Restoration Kit 2 Kit including MegaSpore 180 capsules, MegaPre powders, and MegaMucosa powders for comprehensive gut restoration protocol.
• Total Gut Restoration Kit 3 Kit including MegaSpore 180 capsules, MegaPre capsules, and MegaMucosa powder for comprehensive gut restoration protocol.
• Vaginal Balance Probiotic-powered blend with five Lactobacillus strains and Cranberry Powder for vaginal, urinary tract, immune, and digestive health with 4-in-1 support.
• Pregnancy Support Clinically studied probiotic blend with Lactobacillus strains and ISTILOS B. Infantis (Bifin02) to support healthy mother and baby from preconception through pregnancy and beyond.
• DigestMate 2-in-1 digestive enzyme and probiotic formula combining 14 digestive enzymes with probiotic strains for broad-spectrum digestive support.
• MegaGuard Digestive aid combining licorice polyphenols, artichoke leaf extract, and ginger to support digestive comfort.
• FODMATE Innovative enzyme formula designed for short-term use to support digestive health, particularly for FODMAP-related issues.
• EpicDefense Next-generation immunobiotic formula containing LGG, BB-12, and EpiCor with zinc bisglycinate supporting year-round immune defense, respiratory wellness, and mucosal immune function.
• Mega IgG2000 Capsules Dairy-free immunoglobulin concentrate derived from bovine serum (lactose-free, casein-free) supporting healthy digestion and gut barrier function with 10+ published clinical trials.
• Mega IgG2000 Powder Powder form of dairy-free immunoglobulin concentrate for digestive and gut barrier support.
• PyloGuard Dietary supplement designed to support the body's natural processes for elimination.
• Zenbiome SLEEP Part of Zenbiome collection powered by Bifidobacterium longum 1714, formulated to support occasional sleeplessness and relaxation via gut-brain axis.
• Zenbiome COPE Cognitive support product with Bifidobacterium longum 1714 for targeted support coping with day-to-day stressors and periodic mood changes via gut-brain axis.
• MegaQuin K2+D3 High-potency K2/D3 supplement supporting bone, heart, nerve, mitochondrial, and immune function.
• Omega Ultra SPM Comprehensive full-spectrum fish oil scientifically formulated to support a healthy gut microbiome.
• MegaQuinone High-dose, 100% soy-free Vitamin K2 (MK-7) formulation for bone and cardiovascular health.
• Serene Skin Probiotic-powered skincare supplement supporting radiant, youthful complexion and total body health through gut microbiome optimization.
• FidoSpore Pet-specific probiotic blend clinically shown to promote digestive health in dogs, formulated with grass-fed beef liver extract.

Quantifiable outcome

• BiomeFX provides 99.9% specificity and over 95.7% sensitivity for gut microbiome analysis using whole genome sequencing
• +4 more outcomes

Named customers4 records

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

AI capability5 records

Feature4 records

Partnerships

Four partnerships are on record, tiered core.

• JonacoreTechnology or Integration · 18 May 2026Microbiome Labs relaunched its BiomeFX Functional Microbiome Analysis in partnership with Jona, featuring an AI-powered interpretation layer (JONA AI) trained on over 220,000 peer-reviewed studies. The partnership enables advanced AI-driven microbiome interpretation, translating shotgun metagenomic sequencing data into personalized recommendations for diet, lifestyle, and supplementation.
• Chr. HansencoreTechnology or IntegrationMicrobiome Labs incorporated Chr. Hansen's ISTILOS B. Infantis (Bifin02) probiotic strain into their Pregnancy Support product, marking the introduction of this ingredient to the American probiotic market. Chr. Hansen provides the proprietary B. infantis strain used in the product formulation.
• Synergia Life Sciences Pvt. Ltd.coreTechnology or IntegrationSynergia Life Sciences Pvt. Ltd. is the licensor of HU58 and HU36 Bacillus strains used in MegaSporeBiotic formulations. HU36 is a novel carotenoid-producing probiotic strain that produces high levels of carotenoids at the site of absorption.
• Chr. Hansen (LGG, BB-12 strains)coreTechnology or IntegrationEpicDefense incorporates Chr. Hansen's Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis subsp. lactis BB-12 probiotic strains, which have been clinically studied for respiratory and immune health support.

Scale indicators6 records

Recent moves8 records

Expansion highlights6 records

Broad incumbents

• Integrative Therapeutics: Integrative Therapeutics is a long-established practitioner-channel supplement brand with categories spanning GI, immune, and women's health, directly comparable to Microbiome Labs' practitioner-only distribution model.
• Thorne: Thorne sells practitioner-recommended, clinically validated supplements spanning GI, immune, cognitive, and metabolic categories. It overlaps with Microbiome Labs' multi-category positioning across the same functional and integrative medicine prescribing base.
• Culturelle: Culturelle (i-Health / Chr. Hansen-owned) is one of the most recognized mass-market probiotic brands, sold DTC in mass retail and pharmacies. It is comparable as a Lactobacillus/Bifidobacterium probiotic brand overlapping Microbiome Labs' category but distributed through a much broader consumer channel.
• Designs for Health: Designs for Health is a practitioner-exclusive supplement brand selling evidence-based formulas across GI, immune, metabolic, and cognitive categories, mirroring Microbiome Labs' practitioner-only distribution and multi-category extension strategy.
• Metagenics: Metagenics is a global practitioner-channel supplement company selling condition-specific formulas including GI and immune products. It overlaps with Microbiome Labs' professional sales motion and multi-category practitioner positioning.
• Pure Encapsulations: Pure Encapsulations (owned by Nestlé Health Science) is one of the largest practitioner-grade supplement brands, selling through the same licensed healthcare practitioner channel that Microbiome Labs targets with MegaSporeBiotic and its broader GI/immune lines.

Direct peers

• Seed Health: Seed is a microbiome-focused company selling multi-strain probiotic formulations through both DTC and a professional/practitioner channel (Seed PBC). It is directly comparable to Microbiome Labs given the shared focus on strain-specific science, professional recommendation, and subscription-based probiotic sales.
• Pendulum Therapeutics: Pendulum sells targeted, strain-specific probiotic formulations (notably for glucose and metabolic health) backed by clinical evidence and a professional/recommendation channel. It overlaps directly with Microbiome Labs on next-generation, clinically validated probiotics and strain-level positioning.
• Viome: Viome offers at-home gut microbiome testing combined with personalized supplement and food recommendations, mirroring Microbiome Labs' BiomeFX-plus-supplements diagnostic-to-therapeutic pipeline and AI-driven interpretation layer.

Emerging players

• Klaire Labs: Klaire Labs (part of SFI Health) sells practitioner-grade probiotics and gut-support supplements, making it a niche practitioner-channel competitor in the same target accounts that Microbiome Labs pursues with MegaSporeBiotic and Total Gut Restoration kits.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/channel/UC
• Facebookfacebook.com/groups/microbiomeeducation
• LinkedInlinkedin.com/company/megasporebiotic

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Microbiome Labs