Pulse Infoframe
Pulse Infoframe is a Canadian cloud-based healthcare analytics company that provides the healthie™ 2.0 real-world evidence platform and Rare Central™ registry solutions to biopharma companies, academic medical centers, and rare disease patient advocacy groups in oncology and rare disease.
- Company typePrivate
- Founded2012
- HeadquartersLondon, Canada
- Headcount11–50
- GTM typeB2B
- OfferingSoftware
What Pulse Infoframe does
Pulse Infoframe is a private, cloud-based healthcare analytics company headquartered in London, Ontario, Canada, that builds real-world evidence (RWE) infrastructure for oncology, rare disease, and complex chronic conditions. The company's core offering is the healthie™ 2.0 platform, which integrates patient-reported, clinical, registry, genomic, imaging, and claims data mapped to OMOP, mCode, and CDISC standards, with consent management, NLP-based extraction of free-text clinical notes, and embedded analytics. The platform supports the full evidence lifecycle from natural history studies and patient registries through external comparator arms to post-approval evidence generation, and is delivered with API integrations to Veeva Vault, SharePoint, Tableau, SAS, and Pentaho under ISO 27001 and SOC 2 Type 2 certifications.
The company monetizes through a platform-as-a-service model sold primarily to global biopharmaceutical companies (named customers include Jazz Pharmaceuticals, Immunocore, Endo International, and Sanofi), academic medical centers, and patient advocacy groups running disease-specific registries. Its Rare Central™ product offers three subscription tiers (Starter, Accelerated, Advanced) for rare disease patient registries, with a Pioneer Program offering first-year free access to qualifying patient advocacy groups, and dedicated registries operate for pediatric narcolepsy (CATNAP®), melanoma (GMRN, OMNi), Merkel cell carcinoma, and kidney disease. Pulse Infoframe's go-to-market combines direct enterprise field sales, conference presence at events such as ISPOR and the WORLD Symposium, and ecosystem partnerships with Cytel, Critical Path Institute, Quinten Health, Aparito, InterSystems, and Nested Knowledge. The company is founder-led by Dr. Femida Gwadry-Sridhar and has been operating since 2011-2012 with no disclosed venture capital funding to date, having grown primarily through grants, accelerators, and customer revenue.
Pulse Infoframe firmographics
Firmographics- Name
- Pulse Infoframe
- Legal name
- Pulse Infoframe Inc.
- Website
- https://pulseinfoframe.com
- Company type
- Private
- Founded year
- 2012
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Pulse Infoframe is a Canadian cloud-based healthcare analytics company that provides the healthie™ 2.0 real-world evidence platform and Rare Central™ registry solutions to biopharma companies, academic medical centers, and rare disease patient advocacy groups in oncology and rare disease.
- Ownership category
- akta.pro rank
Where Pulse Infoframe is headquartered
LocationHeadquarters
- HQ city
- London
- HQ country
- Canada
- HQ region
- North America
Offices1 record
Markets served
Pulse Infoframe business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure
Revenue model
- Platform as a Service - Registry Studies: Pulse Infoframe provides a cloud-based real-world evidence platform for building and operating patient registries, natural history studies, and external comparator arms. The company supports longitudinal prospective studies and registries in over 25 diseases in partnership with global pharma partners. Revenue is generated through technology and services bundled together for evidence generation studies.
- Rare Central Tiered Solutions: Three-tiered offering structure (Starter, Accelerated, Advanced) for rare disease patient registries serving patients, advocacy groups, pharmaceutical companies, and academic medical centers. The Pioneer Program offers first year free for selected patient groups.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Annual | Rare Central Starter - Contact registry for patient identification and minimal PROs |
| Subscription | Annual | Rare Central Accelerated - Broader PROs and disease-specific variables |
| Subscription | Annual | Rare Central Advanced - Fully functional registry with natural history data |
Go-to-market motion2 records
Distribution channels2 records
Marketing channels8 records
Pulse Infoframe product offering
Product offeringCore offering
Pulse Infoframe operates a cloud-based real-world evidence (RWE) platform, headlined by healthie™ 2.0, that ingests and harmonizes patient-reported, clinical, registry, genomics, and trial data mapped to OMOP, mCode, and CDISC standards to support biopharmaceutical, academic, and patient advocacy use cases. The company delivers registry builds, natural history studies, external comparator arms, and post-approval evidence generation through its Rare Central™ tiered registry product, Pulse Discovery, and disease-specific registries such as CATNAP®. It bundles its technology platform with in-house epidemiology and operational services for evidence-generation studies across oncology, rare disease, and chronic conditions.
Product overview
Pulse Infoframe offers a unified cloud-based real-world evidence platform architecture centered on healthie™ 2.0 as the core evidence generation engine. The platform portfolio includes Rare Central™ (with Starter, Accelerated, and Advanced tiers) for rare disease patient registries, Discovery for de-risking clinical research, and specialized registries such as CATNAP® for pediatric narcolepsy and oncology registries (GMRN, OMNi, Merkel Cell Carcinoma). The healthie platform integrates patient registries, natural history studies, external comparator arms, and post-approval evidence generation across the drug development lifecycle.
Differentiator
Problem solved
Functional benefit
Brands
- healthie™: Evidence generation platform engaging patients, caregivers, study coordinators, advocates, and industry with consent management, educational materials library, patient reported outcome measures repository, and disease-specific data elements.
- Rare Central
- CATNAP
- Pulse Discovery
Products and services
- healthie™ 2.0 Cloud-based evidence generation platform for real-world data collection, integration, and analysis supporting clinical research in oncology, rare disease, and chronic conditions, with consent management, PRO repository, and disease-specific data elements.
- Rare Central™ Rare disease patient registry platform enabling patients, advocacy groups, pharmaceutical companies, and academic medical centers to collaborate on research using a tiered subscription structure.
- Pulse Discovery Real-world evidence solution that de-risks clinical research by providing access to existing patient data and insights for sponsors planning new studies.
- CATNAP® Pediatric Narcolepsy Registry Pediatric Narcolepsy Registry tracking outcomes for children, adolescents, and their providers in collaboration with Jazz Pharmaceuticals.
- Global Melanoma Research Network (GMRN) Registry Global patient registry for melanoma research providing real-world data on treatment outcomes and patient experiences.
- OMNi (Ocular Melanoma Natural History) Registry
- Merkel Cell Carcinoma Registry
- Global Kidney Platform
Quantifiable outcome
- 40-50% lower labor and technology costs versus traditional models
- +3 more outcomes
Companies that use Pulse Infoframe
Customer profileNamed customers10 records
Segments5 records
Ideal customer profiles3 records
Pulse Infoframe technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- Yes
- API docs
- API detail
Core technology
AI maturity
App detail
Integration5 records
AI capability4 records
Feature8 records
Pulse Infoframe partnerships and signals
Strategic signalPartnerships
15 partnerships are on record, tiered core and minor.
- CytelcoreCytel and Pulse Infoframe are collaborating to support drug development sponsors seeking to implement real-world evidence solutions. Both companies combine expertise to channel real-world evidence toward ground-breaking new treatments in rare disease. Cytel is a leader in advanced analytics for life sciences decision makers with 30 years of experience pioneering new methods.
- Critical Path InstitutecoreCritical Path Institute (C-Path) and Pulse Infoframe are collaborating to advance technologies and tools to further rare disease research and drug development. Organizations will identify opportunities to combine Pulse Infoframe's ambispective data with retrospective data in C-Path's Rare Disease Cures Accelerator-Data and Analytics Platform (RDCA-DAP®).
- Jazz PharmaceuticalscoreJazz collaborated with Pulse Infoframe and leading researchers in pediatric sleep medicine to launch the CATNAP™ Pediatric Narcolepsy Registry – Children, Adolescents, and their providers: The Narcolepsy Assessment Partnership.
- Orphan Disease Center at University of PennsylvaniacoreCreated in collaboration with the Orphan Disease Center at the Perelman School of Medicine, University of Pennsylvania for CDKL5 Registry, launched in March 2018 and funded by the LouLou Foundation.
- LouLou FoundationcoreThe LouLou Foundation funds the CDKL5 Registry dedicated to advancing research into CDKL5 Deficiency Disorder, accelerating development of therapeutics, and supporting clinical trials.
- Timothy Syndrome AlliancecoreTSA and Pulse Infoframe collaborate on the CACNA1C Community Registry to better characterize CACNA1C-related disorders including Timothy Syndrome and LongQT8, focusing on presentation, management, and treatment.
- ImmunocorecoreImmunocore and Pulse Infoframe partnered with leading academic institutions to launch the first global patient registry for uveal melanoma. Patient-reported data helps inform research in this rare form of eye cancer.
- Bowel Cancer AustraliaminorBowel Cancer Australia is the leading community-funded charity dedicated to prevention, early diagnosis, research, and best care for those affected by bowel cancer.
- PIP-UK (Poland Syndrome Support & NEtwork)minorPIP-UK joined Rare Central to create the UK Poland Syndrome Community Register documenting patient experience to advance research and improve health outcomes.
- Alport Syndrome FoundationminorAlport Syndrome Foundation is the leading patient-led, independent, non-profit organization in the US educating and giving voice to the Alport syndrome community.
- Nested KnowledgecorePulse Infoframe and Nested Knowledge announced strategic partnership to power a living evidence ecosystem. Combining real-world data with AI-powered evidence synthesis to accelerate clinical development and market access.
- Endo InternationalcoreEndo partnered with Pulse Infoframe for the GRASP-DC registry (Generating Real-world Ambispective data to Study Participant Treatment outcomes for Dupuytren's Contracture), a non-interventional registry of up to 1,000 patients.
- Global Melanoma Research NetworkminorCollaboration to augment collection of patient relevant melanoma data, resulting in real-time data to inform policy makers and advance research.
- Save Your Skin FoundationminorPartnership with Save Your Skin Foundation to augment collection of patient relevant melanoma data through the Global Melanoma Research Network.
- Castleman Disease Collaborative NetworkminorInitiative dedicated to accelerating research and treatment for Castleman disease, convening 42 experts from 10 different countries to establish first-ever treatment guidelines.
Scale indicators6 records
Recent moves6 records
Expansion highlights6 records
Pulse Infoframe competitors and assessment
Company assessmentBroad incumbents
- Health Catalyst: Healthcare data and analytics platform providing data warehousing, analytics, and improvement services to health systems and life sciences. Adjacent in clinical data integration and analytics depth for clinical and research use cases.
- Veradigm (formerly Allscripts): Large EHR and healthcare data analytics vendor serving providers, life sciences, and RWE customers. Overlaps with Pulse on real-world data infrastructure and biopharma partnerships, though as part of a broader health IT portfolio.
- IQVIA: Largest global CRO and RWE/RWD provider with deep pharma relationships. Overlaps with Pulse on real-world evidence generation and registry operations, but as part of a much broader services portfolio.
Others
- Cytel: Statistical and advanced analytics CRO for biostatistics, clinical trial design, and real-world evidence. Directly named Pulse Infoframe partner; comparable in evidence-generation services for pharma, though focused on biostatistics rather than registries.
Direct peers
- ConcertAI: AI-driven real-world evidence platform for oncology and other therapeutic areas. Directly comparable product category (RWE for biopharma R&D) and target customers; multiple Pulse Infoframe team alumni came from ConcertAI.
- Tempus Labs: AI-enabled precision medicine company combining clinical and molecular data for oncology R&D. Overlaps with Pulse on RWD/RWE, multi-modal data integration (genomics, clinical), and biopharma customers.
- TriNetX: Global health research network enabling clinical trial feasibility, cohort discovery, and real-world studies from EHR data. Comparable in providing biopharma and academic researchers access to de-identified patient-level RWD.
- Flatiron Health: Oncology-focused real-world data and EHR-derived evidence platform, now part of Roche. Closest comparable in oncology RWE and regulatory-grade submissions for biopharma sponsors.
- Syapse: Oncology real-world evidence platform serving health systems, life sciences, and regulators. Comparable in regulatory-grade oncology RWE and biopharma commercial / clinical use cases.
Emerging players
- Mendel: AI platform structuring real-world patient data for clinical research and commercial pharma use cases. Comparable focus on NLP-driven RWD extraction and clinical trial acceleration, but earlier-stage and broader therapeutic reach.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
Pulse Infoframe social profiles
Digital presencePulse Infoframe compliance and trust
Trust signalCompliance2 records
Pulse Infoframe financial estimates
Financial estimateRevenue estimate
Valuation estimate
Pulse Infoframe leadership team
Management profileNumber of profiles
Profiles4 records
Pulse Infoframe funding detail
Funding detailFunding overview
Funding rounds1 record
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Pulse Infoframe M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Pulse Infoframe
What does Pulse Infoframe do?
Pulse Infoframe operates a cloud-based real-world evidence (RWE) platform, headlined by healthie™ 2.0, that ingests and harmonizes patient-reported, clinical, registry, genomics, and trial data mapped to OMOP, mCode, and CDISC standards to support biopharmaceutical, academic, and patient advocacy use cases. The company delivers registry builds, natural history studies, external comparator arms, and post-approval evidence generation through its Rare Central™ tiered registry product, Pulse Discovery, and disease-specific registries such as CATNAP®. It bundles its technology platform with in-house epidemiology and operational services for evidence-generation studies across oncology, rare disease, and chronic conditions.
Is Pulse Infoframe a public or private company?
Pulse Infoframe is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Pulse Infoframe founded?
Pulse Infoframe was founded in 2012. It employs 11 to 50 people.
Where is Pulse Infoframe based?
Pulse Infoframe is headquartered in London, Canada, in the North America region.
How does Pulse Infoframe make money?
Two revenue lines are on record. Platform as a Service - Registry Studies are the primary driver. The others are rare Central Tiered Solutions.
Who are Pulse Infoframe's main competitors?
Broad incumbents on record are Health Catalyst, Veradigm (formerly Allscripts) and IQVIA. Cytel is listed as an others. Direct peers are ConcertAI, Tempus Labs, TriNetX, Flatiron Health and Syapse. Mendel is listed as an emerging player.
Does Pulse Infoframe have an API?
Yes. The healthie platform offers API connectivity for content management integration. The platform can connect to content management services (Veeva Vault, SharePoint, etc.) directly through an API. Data in the repository is regulatory-ready and can be interrogated with standard SQL for analytics purposes.