Pulse Infoframe

What Pulse Infoframe does

Pulse Infoframe is a private, cloud-based healthcare analytics company headquartered in London, Ontario, Canada, that builds real-world evidence (RWE) infrastructure for oncology, rare disease, and complex chronic conditions. The company's core offering is the healthie™ 2.0 platform, which integrates patient-reported, clinical, registry, genomic, imaging, and claims data mapped to OMOP, mCode, and CDISC standards, with consent management, NLP-based extraction of free-text clinical notes, and embedded analytics. The platform supports the full evidence lifecycle from natural history studies and patient registries through external comparator arms to post-approval evidence generation, and is delivered with API integrations to Veeva Vault, SharePoint, Tableau, SAS, and Pentaho under ISO 27001 and SOC 2 Type 2 certifications.

The company monetizes through a platform-as-a-service model sold primarily to global biopharmaceutical companies (named customers include Jazz Pharmaceuticals, Immunocore, Endo International, and Sanofi), academic medical centers, and patient advocacy groups running disease-specific registries. Its Rare Central™ product offers three subscription tiers (Starter, Accelerated, Advanced) for rare disease patient registries, with a Pioneer Program offering first-year free access to qualifying patient advocacy groups, and dedicated registries operate for pediatric narcolepsy (CATNAP®), melanoma (GMRN, OMNi), Merkel cell carcinoma, and kidney disease. Pulse Infoframe's go-to-market combines direct enterprise field sales, conference presence at events such as ISPOR and the WORLD Symposium, and ecosystem partnerships with Cytel, Critical Path Institute, Quinten Health, Aparito, InterSystems, and Nested Knowledge. The company is founder-led by Dr. Femida Gwadry-Sridhar and has been operating since 2011-2012 with no disclosed venture capital funding to date, having grown primarily through grants, accelerators, and customer revenue.

Name

Pulse Infoframe

Legal name

Pulse Infoframe Inc.

Website

https://pulseinfoframe.com

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

11–50 employees

Short description

Pulse Infoframe is a Canadian cloud-based healthcare analytics company that provides the healthie™ 2.0 real-world evidence platform and Rare Central™ registry solutions to biopharma companies, academic medical centers, and rare disease patient advocacy groups in oncology and rare disease.

Ownership category

akta.pro rank

Headquarters

HQ city

London

HQ country

Canada

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Platform as a Service - Registry Studies: Pulse Infoframe provides a cloud-based real-world evidence platform for building and operating patient registries, natural history studies, and external comparator arms. The company supports longitudinal prospective studies and registries in over 25 diseases in partnership with global pharma partners. Revenue is generated through technology and services bundled together for evidence generation studies.
2. Rare Central Tiered Solutions: Three-tiered offering structure (Starter, Accelerated, Advanced) for rare disease patient registries serving patients, advocacy groups, pharmaceutical companies, and academic medical centers. The Pioneer Program offers first year free for selected patient groups.

Pricing tiers

Go-to-market motion2 records

Distribution channels2 records

Marketing channels8 records

Core offering

Pulse Infoframe operates a cloud-based real-world evidence (RWE) platform, headlined by healthie™ 2.0, that ingests and harmonizes patient-reported, clinical, registry, genomics, and trial data mapped to OMOP, mCode, and CDISC standards to support biopharmaceutical, academic, and patient advocacy use cases. The company delivers registry builds, natural history studies, external comparator arms, and post-approval evidence generation through its Rare Central™ tiered registry product, Pulse Discovery, and disease-specific registries such as CATNAP®. It bundles its technology platform with in-house epidemiology and operational services for evidence-generation studies across oncology, rare disease, and chronic conditions.

Product overview

Pulse Infoframe offers a unified cloud-based real-world evidence platform architecture centered on healthie™ 2.0 as the core evidence generation engine. The platform portfolio includes Rare Central™ (with Starter, Accelerated, and Advanced tiers) for rare disease patient registries, Discovery for de-risking clinical research, and specialized registries such as CATNAP® for pediatric narcolepsy and oncology registries (GMRN, OMNi, Merkel Cell Carcinoma). The healthie platform integrates patient registries, natural history studies, external comparator arms, and post-approval evidence generation across the drug development lifecycle.

Differentiator

Problem solved

Functional benefit

Brands

• healthie™: Evidence generation platform engaging patients, caregivers, study coordinators, advocates, and industry with consent management, educational materials library, patient reported outcome measures repository, and disease-specific data elements.
• Rare Central
• CATNAP
• Pulse Discovery

Products and services

• healthie™ 2.0 Cloud-based evidence generation platform for real-world data collection, integration, and analysis supporting clinical research in oncology, rare disease, and chronic conditions, with consent management, PRO repository, and disease-specific data elements.
• Rare Central™ Rare disease patient registry platform enabling patients, advocacy groups, pharmaceutical companies, and academic medical centers to collaborate on research using a tiered subscription structure.
• Pulse Discovery Real-world evidence solution that de-risks clinical research by providing access to existing patient data and insights for sponsors planning new studies.
• CATNAP® Pediatric Narcolepsy Registry Pediatric Narcolepsy Registry tracking outcomes for children, adolescents, and their providers in collaboration with Jazz Pharmaceuticals.
• Global Melanoma Research Network (GMRN) Registry Global patient registry for melanoma research providing real-world data on treatment outcomes and patient experiences.
• OMNi (Ocular Melanoma Natural History) Registry
• Merkel Cell Carcinoma Registry
• Global Kidney Platform

Quantifiable outcome

• 40-50% lower labor and technology costs versus traditional models
• +3 more outcomes

Named customers10 records

Segments5 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration5 records

AI capability4 records

Feature8 records

Partnerships

15 partnerships are on record, tiered core and minor.

• CytelcoreStrategic or Co-development PartnerCytel and Pulse Infoframe are collaborating to support drug development sponsors seeking to implement real-world evidence solutions. Both companies combine expertise to channel real-world evidence toward ground-breaking new treatments in rare disease. Cytel is a leader in advanced analytics for life sciences decision makers with 30 years of experience pioneering new methods.
• Critical Path InstitutecoreStrategic or Co-development PartnerCritical Path Institute (C-Path) and Pulse Infoframe are collaborating to advance technologies and tools to further rare disease research and drug development. Organizations will identify opportunities to combine Pulse Infoframe's ambispective data with retrospective data in C-Path's Rare Disease Cures Accelerator-Data and Analytics Platform (RDCA-DAP®).
• Jazz PharmaceuticalscoreStrategic or Co-development PartnerJazz collaborated with Pulse Infoframe and leading researchers in pediatric sleep medicine to launch the CATNAP™ Pediatric Narcolepsy Registry – Children, Adolescents, and their providers: The Narcolepsy Assessment Partnership.
• Orphan Disease Center at University of PennsylvaniacoreStrategic or Co-development PartnerCreated in collaboration with the Orphan Disease Center at the Perelman School of Medicine, University of Pennsylvania for CDKL5 Registry, launched in March 2018 and funded by the LouLou Foundation.
• LouLou FoundationcoreStrategic or Co-development PartnerThe LouLou Foundation funds the CDKL5 Registry dedicated to advancing research into CDKL5 Deficiency Disorder, accelerating development of therapeutics, and supporting clinical trials.
• Timothy Syndrome AlliancecoreStrategic or Co-development PartnerTSA and Pulse Infoframe collaborate on the CACNA1C Community Registry to better characterize CACNA1C-related disorders including Timothy Syndrome and LongQT8, focusing on presentation, management, and treatment.
• ImmunocorecoreStrategic or Co-development PartnerImmunocore and Pulse Infoframe partnered with leading academic institutions to launch the first global patient registry for uveal melanoma. Patient-reported data helps inform research in this rare form of eye cancer.
• Bowel Cancer AustraliaminorStrategic or Co-development PartnerBowel Cancer Australia is the leading community-funded charity dedicated to prevention, early diagnosis, research, and best care for those affected by bowel cancer.
• PIP-UK (Poland Syndrome Support & NEtwork)minorStrategic or Co-development PartnerPIP-UK joined Rare Central to create the UK Poland Syndrome Community Register documenting patient experience to advance research and improve health outcomes.
• Alport Syndrome FoundationminorStrategic or Co-development PartnerAlport Syndrome Foundation is the leading patient-led, independent, non-profit organization in the US educating and giving voice to the Alport syndrome community.
• Nested KnowledgecoreTechnology or IntegrationPulse Infoframe and Nested Knowledge announced strategic partnership to power a living evidence ecosystem. Combining real-world data with AI-powered evidence synthesis to accelerate clinical development and market access.
• Endo InternationalcoreStrategic or Co-development PartnerEndo partnered with Pulse Infoframe for the GRASP-DC registry (Generating Real-world Ambispective data to Study Participant Treatment outcomes for Dupuytren's Contracture), a non-interventional registry of up to 1,000 patients.
• Global Melanoma Research NetworkminorStrategic or Co-development PartnerCollaboration to augment collection of patient relevant melanoma data, resulting in real-time data to inform policy makers and advance research.
• Save Your Skin FoundationminorStrategic or Co-development PartnerPartnership with Save Your Skin Foundation to augment collection of patient relevant melanoma data through the Global Melanoma Research Network.
• Castleman Disease Collaborative NetworkminorStrategic or Co-development PartnerInitiative dedicated to accelerating research and treatment for Castleman disease, convening 42 experts from 10 different countries to establish first-ever treatment guidelines.

Scale indicators6 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• Health Catalyst: Healthcare data and analytics platform providing data warehousing, analytics, and improvement services to health systems and life sciences. Adjacent in clinical data integration and analytics depth for clinical and research use cases.
• Veradigm (formerly Allscripts): Large EHR and healthcare data analytics vendor serving providers, life sciences, and RWE customers. Overlaps with Pulse on real-world data infrastructure and biopharma partnerships, though as part of a broader health IT portfolio.
• IQVIA: Largest global CRO and RWE/RWD provider with deep pharma relationships. Overlaps with Pulse on real-world evidence generation and registry operations, but as part of a much broader services portfolio.

Others

• Cytel: Statistical and advanced analytics CRO for biostatistics, clinical trial design, and real-world evidence. Directly named Pulse Infoframe partner; comparable in evidence-generation services for pharma, though focused on biostatistics rather than registries.

Direct peers

• ConcertAI: AI-driven real-world evidence platform for oncology and other therapeutic areas. Directly comparable product category (RWE for biopharma R&D) and target customers; multiple Pulse Infoframe team alumni came from ConcertAI.
• Tempus Labs: AI-enabled precision medicine company combining clinical and molecular data for oncology R&D. Overlaps with Pulse on RWD/RWE, multi-modal data integration (genomics, clinical), and biopharma customers.
• TriNetX: Global health research network enabling clinical trial feasibility, cohort discovery, and real-world studies from EHR data. Comparable in providing biopharma and academic researchers access to de-identified patient-level RWD.
• Flatiron Health: Oncology-focused real-world data and EHR-derived evidence platform, now part of Roche. Closest comparable in oncology RWE and regulatory-grade submissions for biopharma sponsors.
• Syapse: Oncology real-world evidence platform serving health systems, life sciences, and regulators. Comparable in regulatory-grade oncology RWE and biopharma commercial / clinical use cases.

Emerging players

• Mendel: AI platform structuring real-world patient data for clinical research and commercial pharma use cases. Comparable focus on NLP-driven RWD extraction and clinical trial acceleration, but earlier-stage and broader therapeutic reach.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/Pulse-Infoframe-Inc-913164155442668
• LinkedInlinkedin.com/company/pulseinfoframe
• Xx.com/pulseinfoframe

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Pulse Infoframe