Dentognostics GmbH
dentognostics GmbH is a German medical device company that develops the patented aMMP-8 biomarker-based rapid saliva test and ORALyzer EXPERT reader for early chairside detection of oral collagen degradation, serving dental practices, large DSOs, and adjacent medical specialties.
- Company typePrivate
- Founded2002
- HeadquartersJena, Germany
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Dentognostics GmbH does
dentognostics GmbH is a privately-held German medical device company headquartered in Solingen, founded in 2002, that develops and manufactures the aMMP-8 (active Matrix Metalloproteinase-8) biomarker technology used for early detection of subclinical collagen degradation in the oral cavity. The company's core product system consists of the ORALyzer EXPERT digital reader and a family of rapid test kits (PerioSafe PRO DRS, ImplantSafe DR, PerioSafe ImplantSafe POOL DR, and PerioSafe Vitamin D) that deliver quantitative chairside results in approximately five minutes, complemented by oral care consumables (toothpaste and mouthwash under the PerioSafe brand). The technology is positioned as a 94%-accurate, 2-3x improvement over traditional bleeding-on-probing diagnostics and is reported to be the only European point-of-care aMMP-8 system with in-vitro diagnostics authorization for direct use in dental practices.
The company serves general dental practices, preventive dentists, implantologists, dental hygienists, sports dentistry practitioners (including customers such as FC Bayern München Women and SKN St. Pölten), and holistic/biological dentistry practices, with extensions into diabetology and gynecology framed around the oral-systemic health link. Go-to-market combines a product-led Starter-Kit motion with expert consultations, an Academy-based training and certification program (OralFitness Coach, ImplantSafe Coach, OralFitness Center and ImplantSafe Center quality seals) delivered in partnership with Deutsche Mundgesundheitsstiftung, and enterprise field sales to large dental service organizations such as PDS Health and Dental365 in the U.S. Revenue derives from hardware sales of the reader device, recurring consumable test kit purchases, academy/training services, and quality-seal licensing, though specific pricing is not publicly disclosed. The company reports an installed base of 2,000+ dentists and 145,000+ patients tested, with usage cited by NASA, ESA, and multiple universities.
In 2023-2024, dentognostics raised a strategic round led by Dental365 and Dental Innovation Alliance, appointed a President of North American Operations and a VP of International Business Development, and is actively expanding from its European base into the U.S. market via DSO partnerships, while broadening its product line into adjacent medical verticals.
Dentognostics GmbH firmographics
Firmographics- Name
- Dentognostics GmbH
- Legal name
- dentognostics GmbH
- Website
- https://dentognostics.de
- Company type
- Private
- Founded year
- 2002
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- dentognostics GmbH is a German medical device company that develops the patented aMMP-8 biomarker-based rapid saliva test and ORALyzer EXPERT reader for early chairside detection of oral collagen degradation, serving dental practices, large DSOs, and adjacent medical specialties.
- Ownership category
- akta.pro rank
Dentognostics GmbH industry classification
Industry- Product category
- Dental Diagnostics
- NAICS
- Dental Equipment and Supplies Manufacturing (339114), Polish and Other Sanitation Good Manufacturing (325612)
- SIC
- Dental Equipment & Supplies (3843), In Vitro & In Vivo Diagnostic Substances (2835), Perfumes, Cosmetics & Other Toilet Preparations (2844)
- akta.pro primary industry
- Caries Risk Assessment & Preventive Planning (HLABAHAE)
- akta.pro secondary industries
- Preventive & Routine General Dentistry (Exams/Cleanings/Sealants/Fluoride) (HLABAAAA), Oral Care Products (Toothpaste, Mouthwash, Dental Floss, Whitening) (CRADAMAA)
Keywords
Where Dentognostics GmbH is headquartered
LocationHeadquarters
- HQ city
- Jena
- HQ country
- Germany
- HQ region
- Europe
Offices1 record
Markets served
Dentognostics GmbH business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain
Revenue model
- Diagnostic Test Products: Sale of aMMP-8 rapid test products including PerioSafe PRO DRS, ImplantSafe DR, PerioSafe ImplantSafe POOL DR, and ORALyzer EXPERT systems. These are point-of-care diagnostic kits for measuring collagen degradation markers in saliva and gingival crevicular fluid.
- Consumables and Reagents: Ongoing sales of test consumables and reagents for the ORALyzer system and rapid tests, including PerioSafe Vitamin D tests and oral care products (toothpaste, mouthwash).
- Academy and Training Services: Revenue from online Academy (academy-dentognostics.de), training programs, certifications (OralFitness Coach, ImplantSafe Coach), and Masterclass qualification programs conducted with Deutsche Mundgesundheitsstiftung (DMS) partnership.
- Quality Seal and Certification Programs: Practice certification programs including OralFitness Center and ImplantSafe Center quality seals, providing certified practices with marketing advantages and patient trust-building tools.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Pay-as-you-go | Starter-Kit for practice evaluation |
Go-to-market motion4 records
Distribution channels4 records
Marketing channels7 records
Dentognostics GmbH product offering
Product offeringCore offering
Dentognostics GmbH develops, manufactures, and sells point-of-care diagnostic systems based on its patented aMMP-8 biomarker technology for early detection of oral collagen degradation. Its product portfolio includes the ORALyzer EXPERT digital reader device, PerioSafe and ImplantSafe rapid test kits that measure aMMP-8 in saliva or gingival crevicular fluid, the PerioSafe Vitamin D test, and PerioSafe oral care consumables (toothpaste and mouthwash). The company also monetizes complementary Academy training, certification programs (OralFitness Coach, ImplantSafe Coach), and licensed quality seals (OralFitness Center, ImplantSafe Center) for dental practices.
Product overview
Dentognostics GmbH is the developer and manufacturer of the aMMP-8 biomarker technology for early detection of collagen degradation processes. The product portfolio consists of diagnostic testing products (ORALyzer® EXPERT reader device, PerioSafe® PRO DRS, ImplantSafe® DR, PerioSafe® ImplantSafe® POOL DR, PerioSafe® Vitamin D) and oral care consumables (PerioSafe® Mundgesundheits-Zahncreme and PerioSafe® Mundgesundheits-Spülung). The diagnostic products work together as a system: the ORALyzer® EXPERT provides digital readout of rapid test results while the PerioSafe® and ImplantSafe® test kits measure aMMP-8 biomarker concentrations in saliva or gingival fluid. The company has been developing this technology since 2002 and serves over 2,000 dental practices.
Differentiator
Problem solved
Functional benefit
Brands
- ORALyzer® EXPERT: Digital rapid test system for aMMP-8 and Vitamin D determination at point-of-care
- PerioSafe® PRO DRS
- PerioSafe® Vitamin D
- ImplantSafe® DR
- PerioSafe® ImplantSafe® POOL DR
- OralFitness Center®
- ImplantSafe Center®
- OralFitness Coach®
- ImplantSafe Coach®
Products and services
- ORALyzer EXPERT Compact point-of-care digital reader that quantitatively evaluates aMMP-8 rapid tests and delivers results within 5 minutes at chairside; designed for dental practices and dental service organizations.
- PerioSafe PRO DRS Quantitative rapid test measuring aMMP-8 concentration in saliva for systematic screening of prevention patients; used for interdisciplinary diagnostics and as complementary basic diagnostics for professional teeth cleaning and oral examination.
- PerioSafe Vitamin D Rapid point-of-care test that measures vitamin D levels to support calcium and phosphate metabolism and broader physiological processes relevant to oral fitness.
- ImplantSafe DR Quantitative rapid test measuring aMMP-8 concentration in gingival crevicular fluid (PISF/GCF) for screening and monitoring of periodontal and peri-implant patients, identifying early degradation around implants and detecting treatment responders vs. non-responders.
- PerioSafe ImplantSafe POOL DR Quantitative pooled rapid test measuring aMMP-8 concentration in PISF/GCF for screening and monitoring of periodontal and peri-implant status at up to four implants or teeth in a single test.
- PerioSafe Mundgesundheits-Zahncreme Oral health toothpaste with antiviral, antimicrobial, and antibacterial MicroSilver BG, provitamin panthenol, zinc gluconate, and sodium fluoride to inhibit plaque formation for up to 12 hours and support gum regeneration.
- PerioSafe Mundgesundheits-Spülung Oral health mouth rinse with MicroSilver BG providing sustained plaque reduction for up to 12 hours, supporting treatment of oral inflammation and aphthae.
- Dentognostics Academy (OralFitness Coach / ImplantSafe Coach training and certification) Paid training, certification, and Masterclass programs that qualify dental professionals (e.g., OralFitness Coach, ImplantSafe Coach) to use the ORALyzer system and provide preventive and implant-safety services.
- OralFitness Center and ImplantSafe Center quality seals Licensed practice quality seals (OralFitness Center, ImplantSafe Center) granted to qualified dental practices, providing marketing differentiation and patient trust.
Quantifiable outcome
- 94% accuracy in detecting collagen degradation
- +4 more outcomes
Companies that use Dentognostics GmbH
Customer profileNamed customers7 records
Segments6 records
Ideal customer profiles4 records
Dentognostics GmbH technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature5 records
Dentognostics GmbH partnerships and signals
Strategic signalPartnerships
Seven partnerships are on record, tiered core and flagship.
- Deutsche Mundgesundheitsstiftung (DMS)coreDMS is a cooperation partner for conducting Masterclass qualification programs. Together they offer certification programs including OralFitness Coach, ImplantSafe Coach, OralFitness Center, and ImplantSafe Center quality seals for qualified dental practices.
- NASA (National Aeronautics and Space Administration)flagshipNASA uses dentognostics aMMP-8 technology for oral health monitoring of astronauts. This partnership validates the scientific credibility and advanced capabilities of the technology for space medicine applications.
- ESA (European Space Agency)flagshipESA uses dentognostics aMMP-8 technology in collaboration with NASA for oral health research of astronauts. Represents the highest level of scientific validation for the technology.
- University of HelsinkicoreLeading research university using aMMP-8 technology for scientific research in oral-systemic health. One of several prestigious academic institutions worldwide supporting evidence base.
- Philipps-Universität MarburgcoreGerman university using aMMP-8 technology for research in oral health and oral-systemic disease connections.
- Universität UlmcoreGerman university conducting scientific research using aMMP-8 technology for oral-systemic health studies.
- Professional Associations (DGDH, DGSZM, VDDI, VDDH, DZV, GSAAM, Gesundheitssenat, Senat der Wirtschaft)coreNetwork of renowned professional associations that recognize and endorse aMMP-8 technology for oral health applications. Provides credibility and professional network access.
Scale indicators6 records
Recent moves6 records
Expansion highlights7 records
Dentognostics GmbH competitors and assessment
Company assessmentBroad incumbents
- Philips Oral Healthcare: Major player in the consumer and professional oral-care market (Sonicare, AirFloss). Comparable to Dentognostics in the preventive/consumer oral-care adjacency and the dentist-recommendation channel.
- 3M Oral Care: Diversified dental and orthodontic business offering preventive products, restoratives, and digital oral health solutions. Represents a large, well-funded incumbent that overlaps with Dentognostics' preventive and consumer oral-care lines.
- Colgate-Palmolive: Owner of Colgate, meridol, and other oral-care brands. Comparable to Dentognostics via its PerioSafe toothpaste and mouthwash line and its longstanding dental professional recommendation channel.
- Henry Schein: Largest distributor of dental supplies, equipment, and services to dental practices and DSOs. As Dentognostics' products route through enterprise DSO customers, Henry Schein is a powerful channel incumbent and potential partner or competitor.
- Sunstar (GUM): Global oral-care company with toothbrushes, toothpastes, mouthwashes, and professional preventive products. Relevant to Dentognostics' PerioSafe consumer oral-care line and its preventive dentistry positioning.
- Dentsply Sirona: Global leader in dental equipment, consumables, and digital dentistry across general dentistry, endodontics, and implants. A broad incumbent that could expand into chairside diagnostics and outcompete smaller specialists like Dentognostics.
Direct peers
- Perio Protect: Specializes in prescription tray-based periodontal therapy and adjacent diagnostics. Competes with Dentognostics in the preventive periodontitis treatment pathway and shares the dental-practice channel.
- OralDNA Labs: Saliva-based diagnostics provider for periodontitis and other oral/systemic disease risk, with MyPerioPath and other tests sold through dental professionals. Directly overlaps with Dentognostics' aMMP-8 point-of-care testing category.
Emerging players
- Millennium Dental Technologies: Provider of the PerioLase MVP-7 dental laser for LANAP periodontal therapy. Operates in the same periodontitis-treatment workflow as Dentognostics, with a focus on minimally invasive treatment rather than diagnostics.
- Quotient Therapeutics: Developer of molecular diagnostics and biomarker-based tests for inflammatory and dental disease. Overlaps with Dentognostics' biomarker-driven approach to periodontal and oral-systemic disease detection.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
Dentognostics GmbH social profiles
Digital presenceDentognostics GmbH financial estimates
Financial estimateRevenue estimate
Valuation estimate
Dentognostics GmbH leadership team
Management profileNumber of profiles
Profiles2 records
Dentognostics GmbH funding detail
Funding detailFunding overview
Funding rounds1 record
Investors2 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Dentognostics GmbH M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Dentognostics GmbH
What does Dentognostics GmbH do?
Dentognostics GmbH develops, manufactures, and sells point-of-care diagnostic systems based on its patented aMMP-8 biomarker technology for early detection of oral collagen degradation. Its product portfolio includes the ORALyzer EXPERT digital reader device, PerioSafe and ImplantSafe rapid test kits that measure aMMP-8 in saliva or gingival crevicular fluid, the PerioSafe Vitamin D test, and PerioSafe oral care consumables (toothpaste and mouthwash). The company also monetizes complementary Academy training, certification programs (OralFitness Coach, ImplantSafe Coach), and licensed quality seals (OralFitness Center, ImplantSafe Center) for dental practices.
Is Dentognostics GmbH a public or private company?
Dentognostics GmbH is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Dentognostics GmbH founded?
Dentognostics GmbH was founded in 2002. It employs 11 to 50 people.
Where is Dentognostics GmbH based?
Dentognostics GmbH is headquartered in Jena, Germany, in the Europe region.
How does Dentognostics GmbH make money?
Four revenue lines are on record. Diagnostic Test Products are the primary driver. The others are consumables and Reagents, academy and Training Services and quality Seal and Certification Programs.
Who are Dentognostics GmbH's main competitors?
Broad incumbents on record are Philips Oral Healthcare, 3M Oral Care, Colgate-Palmolive, Henry Schein, Sunstar (GUM) and Dentsply Sirona. Direct peers are Perio Protect and OralDNA Labs. Emerging players are Millennium Dental Technologies and Quotient Therapeutics.
Does Dentognostics GmbH have an API?
No public API is recorded for Dentognostics GmbH.
What industry is Dentognostics GmbH in?
Dentognostics GmbH's product category is Dental Diagnostics. Its primary akta.pro industry code is HLABAHAE, Caries Risk Assessment & Preventive Planning, with a secondary code of HLABAAAA, Preventive & Routine General Dentistry (Exams/Cleanings/Sealants/Fluoride). Its NAICS code is 339114 and its SIC code is 3843.