CyncHealth

What CyncHealth does

CyncHealth is a 501(c)(3) nonprofit health data utility (HDU) that operates a statewide Health Information Exchange (HIE) and related interoperability services for healthcare providers, payers, and public health agencies in the Midwest United States. Founded in 2008 (previously known as Nebraska Health Information Initiative, NEHII), the organization administers the Nebraska HIT Board under the Population Health Information Act (LB 1183, 2020) and serves as the statutorily designated statewide HIE for Nebraska, with a regional expansion into Minnesota via CyncHealth Minnesota and (until May 2026) into Iowa via CyncHealth Iowa.

The core platform ingests clinical HL7 messages, claims data, pharmacy data, and social determinants of health (SDOH) into an Integrated Data Repository (IDR) built in partnership with Quanta Health, producing FHIR-ready structured outputs. CyncHealth's product portfolio spans the HIE clinical portal, Nebraska's Prescription Drug Monitoring Program (PDMP), Event Notification Services (ENS), a Direct Secure Messaging HISP, a Provider Portal, a closed-loop Social Care Referral Platform powered by Unite Us, and chronic disease registries. The platform is HITRUST-certified and SOC 2 Type II attested, connected to eHealth Exchange for nationwide query-based record retrieval, and supports USCDI standards and FHIR-based APIs.

CyncHealth connects over 1,100 healthcare facilities and supports more than 5 million lives. Revenue is generated through state and federal grants/contracts (notably a $13.6M CDC-funded state contract in 2024), standard multi-year participation agreements with hospitals, clinics, payers, and public health departments, tiered add-on subscriptions (e.g., DirectXDR), and paid consulting/analytics services through CyncHealth Advisors. The Nebraska Healthcare Collaborative and Midwest Institute for Community Health (MICH) function as subsidiaries providing research data marts and community health program management. Distribution is direct via account management teams with participation agreements signed electronically; go-to-market emphasizes public-private governance, regulatory alignment (CMS Aligned Network, eHealth Exchange), and federal interoperability positioning following the July 2025 White House CMS Aligned Network pledge.

Name

CyncHealth

Legal name

CyncHealth

Website

https://cynchealth.org

Company type

Private

Founded year

2017

Operating status

Operating

Headcount range

11–50 employees

Short description

CyncHealth is a nonprofit health data utility operating a statewide Health Information Exchange connecting 1,100+ healthcare facilities across Nebraska and Minnesota, serving hospitals, payers, and public health agencies with clinical, claims, pharmacy, and SDOH interoperability for over 5 million patients.

Ownership category

akta.pro rank

Product category

Health Information Exchange / Healthcare Interoperability

NAICS

Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (518), Information (51), Administration of Public Health Programs (923120)

SIC

Services-Computer Programming, Data Processing, Etc. (7370), Services-Health Services (8000)

akta.pro primary industry

HIE Platforms & Network Services (Community/Regional/National) (HLACABAB)

akta.pro secondary industries

Data Access, Sharing & Marketplace Platforms (incl. TEFCA/QHIN enablement) (HLACAIAL), Healthcare Terminology, Ontology & Code Set Management (SNOMED/LOINC/ICD/RxNorm) (HLACAIAF), Consent, Authorization & Data Sharing Governance (opt-in/opt-out, DS4P) (HLACABAG)

Keywords

• Health information exchange
• Prescription drug monitoring
• Health data utility
• Clinical data interoperability
• Social care referrals

Headquarters

HQ city

La Vista

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Infrastructure, Operations, Marketing or Sales

Revenue model

1. Government Grants and State Contracts: CyncHealth receives government grants and state contracts funded by CDC and other federal/state programs. Nebraska received an $18.7M CDC grant, with CyncHealth receiving $13.6M in state contracts to support federal health data initiatives including vaccine and autism research.
2. Healthcare Data Exchange Participation Fees: Healthcare facilities and payers pay participation fees to join the HIE network. Standard terms are maintained for all participants. The organization operates as a 501(c)(3) nonprofit.
3. Professional Services and Consulting: CyncHealth Advisors provides paid consulting arrangements for infrastructure, initiatives, and programs. Services are available for payers, hospitals, government agencies, other HIEs, employers, and quality initiatives including ad hoc custom reporting.
4. Data Analytics and Insights Services: CyncHealth Advisors supports participants to analyze trends in utilization, determine appropriate care management strategies, enable effective review to detect and mitigate fraud, waste and abuse, and direct funding to high-value care initiatives.

Pricing tiers

Go-to-market motion3 records

Distribution channels6 records

Marketing channels7 records

Core offering

CyncHealth operates a Health Data Utility (HDU) that aggregates clinical (HIE), claims, pharmacy, and social determinants of health (SDOH) data into a centralized statewide network for Nebraska (and previously Iowa/Minnesota). Its core offerings include a longitudinal Health Information Exchange, the Nebraska Prescription Drug Monitoring Program (PDMP), Event Notification Services, a Social Care Referral Platform powered by Unite Us, Direct Secure Messaging, and a Provider Portal — sold to hospitals, payers, and public health agencies via standard subscription participation agreements.

Product overview

CyncHealth is a health data utility (HDU) operating as a 501(c)(3) nonprofit organization that administers health information exchange, prescription drug monitoring, and population health support. The core platform consists of the Health Information Exchange (HIE) for longitudinal patient records, Prescription Drug Monitoring Program (PDMP), Event Notification Services (ENS), and Social Care Referral Platform (Closed Loop Referrals) powered by Unite Us. Additional modules include Direct Secure Messaging (with Web Portal and DirectXDR options), Provider Portal, Interoperability Solutions, and Workflow Efficiencies. A new Integrated Data Repository (IDR) was launched in partnership with Quanta Health. The organization also encompasses subsidiaries: Nebraska Healthcare Collaborative for data analytics, Midwest Institute for Community Health for community health projects, and CyncHealth Advisors for consulting services. The network connects over 5 million lives and 1,100+ facilities across Nebraska and Iowa.

Differentiator

Problem solved

Functional benefit

Brands

• CyncHealth Advisors: Team of healthcare and data science experts providing consulting and analytics services to HDU participants
• Midwest Institute for Community Health (MICH)
• Nebraska Healthcare Collaborative

Products and services

• Health Information Exchange (HIE) Secure, electronic, query-based health information exchange enabling instant sharing of health information among authorized participating healthcare providers; provides longitudinal health records via a web-based clinical portal connecting hospitals, clinics, long-term care facilities, and other healthcare providers across Nebraska and Iowa. Connects to eHealth Exchange for nationwide reach.
• Prescription Drug Monitoring Program (PDMP) Nebraska's statewide Prescription Drug Monitoring Program that tracks all prescription drugs, providing clinicians with comprehensive medication history to improve patient care, reduce errors, enhance workflow efficiency, and ensure compliance with state and federal law.
• Event Notification Services (ENS) Automated health information alerts from discharging acute and critical access hospitals to care coordinating providers. Messages assigned care managers/providers when patients have events such as Emergency Department or Inpatient admissions/discharges, supporting CMS mandate compliance and reducing readmissions.
• Social Care Referral Platform (Closed Loop Referrals) Closed-loop referral platform (CLRP) powered by Unite Us that connects healthcare with social care, enabling providers to screen for SDOH needs, refer patients to local services, track outcomes, and strengthen collaboration with community partners.
• Direct Secure Messaging Health Information Service Provider (HISP) service utilizing the Direct Standard for exchanging health information between healthcare entities. Includes Web Portal option at no additional cost and optional DirectXDR for sending secure messages directly into EHRs at additional annual cost.
• Provider Portal Lightweight, streamlined platform supporting care coordination with real-time patient health data; reduces cost and burden and improves efficiency for participating providers. The Iowa Provider Portal was launched in early 2025 following a Phase One demonstration in March 2024.
• Integrated Data Repository (IDR) Transformative data platform built in partnership with Quanta Health. Ingests HL7 messages, claims, and medication history data and transforms them into clean, structured, deduplicated outputs. FHIR-ready architecture for standards-based API enablement with real-time deduplication and replay readiness.
• CyncHealth Advisors Consulting Services Healthcare and data science consulting team supporting CyncHealth participants to analyze trends in utilization, determine appropriate care management strategies, detect and mitigate fraud, waste, and abuse, and direct funding to high-value care initiatives through paid engagements.
• Nebraska Healthcare Collaborative Data Services Nonprofit subsidiary that curates health data marts from the statewide Health Data Utility including electronic health records, social service referrals, prescription monitoring, and claims data, supporting researchers, policymakers, and public health organizations.

Quantifiable outcome

• Over 423 million clinical viewer logins in 2024, demonstrating high platform utilization
• +6 more outcomes

Named customers9 records

Segments6 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration5 records

Feature9 records

Partnerships

Eight partnerships are on record, tiered core and minor.

• Health CatalystcoreTechnology or Integration · 5 August 2025Health Catalyst partnered with CyncHealth Nebraska to provide more accurate, timely, and secure Continuity of Care Documents (CCDs) using its Ninja Universe technology—an advanced parsing tool purpose-built to streamline health data exchange. The partnership builds on an existing relationship with CyncHealth Iowa (announced November 2024). Health Catalyst is a leading provider of data and analytics technology and services to healthcare organizations (Nasdaq: HCAT).
• Quanta HealthcoreTechnology or Integration · 11 July 2025CyncHealth partnered with Quanta Health to launch a transformative Integrated Data Repository (IDR) — a foundational leap in simplifying and scaling healthcare data interoperability. Built for performance, flexibility, and rapid integration, the IDR is designed to reshape how healthcare organizations access and act on clinical and claims data at scale. Quanta Health was founded to tackle unreliable, inconsistent healthcare data and helps organizations bridge disparate systems and unlock clinical information value.
• Leavitt PartnerscoreStrategic or Co-development Partner · 22 October 2024CyncHealth collaborated with Leavitt Partners, a healthcare-focused private equity firm founded by former U.S. HHS Secretary Michael Leavitt, to release a 'Playbook for SDOH Referral Management and Data Exchange.' The playbook addresses critical barriers in social determinants of health data collection: lack of understanding of federal policies and complexities of data workflows. Leavitt Partners brings federal digital health policy expertise to the partnership.
• Unite UscoreTechnology or IntegrationCyncHealth's Closed Loop Referral Platform is powered by Unite Us, connecting healthcare with social care to enable providers to address social determinants of health, screen for needs, refer patients to local services, track outcomes, and strengthen collaboration with community partners. United Way partners as the local 2-1-1 Navigator to ensure higher rates of fulfilled referrals.
• eHealth ExchangecoreTechnology or IntegrationCyncHealth is connected to eHealth Exchange, the largest query-based health information network in the country. This connection enables health records to follow patients wherever they seek care, linking federal agencies and healthcare entities for seamless data sharing nationwide.
• United WayminorStrategic or Co-development PartnerUnited Way partners with CyncHealth as the local 2-1-1 Navigator to support the social care referral platform, ensuring higher rates of fulfilled social service referrals for patients with social determinants of health needs.
• Project Partners (Nebraska Healthcare Collaborative)coreStrategic or Co-development PartnerThe Nebraska Healthcare Collaborative partners with healthcare organizations for research and population health projects including CHI Health, Children's Hospital & Medical Center, Creighton University, University of Nebraska Medical Center (UNMC), University of Nebraska at Omaha (UNO), Healthy Housing, Iowa Healthcare Collaborative, Lutheran Family Services, Nebraska Cancer Coalition, Prairie Stem, Ronald McDonald House Charities in Omaha, University of Iowa, and UNK.
• Nebraska Health Information Technology (HIT) BoardcoreOthersCyncHealth administers the Nebraska HIT Board, established by the Population Health Information Act (LB 1183, 2020). The Board of 17 members appointed by the Governor oversees criteria for data collection and disbursement, ensures technological standards for PDMP reporting, and provides governance oversight for privacy and security protections under HIPAA.

Scale indicators12 records

Recent moves7 records

Expansion highlights5 records

Direct peers

• Manifest MedEx: Manifest MedEx is California's largest nonprofit HIE, offering clinical data exchange, notifications, and analytics to providers, health plans, and public health agencies. Comparable as a large-scale, nonprofit, statewide HIE serving hospitals, payers, and government partners.
• Healthix: Healthix is one of the largest public HIEs in the U.S., connecting New York City and Long Island providers with longitudinal records, event notifications, and population health analytics. Closely comparable in scale (millions of lives), nonprofit model, and clinical/analytics service mix.
• Contexture: Contexture is the merged statewide HIE for Arizona and Colorado (formerly CORHIO and HealthCurrent), serving hospitals, providers, payers, and public health. Directly comparable to CyncHealth as a multi-state nonprofit HIE operating under similar governance and data-sharing frameworks.
• CRISP (Chesapeake Regional Information System for Our Patients): CRISP is a nonprofit HIE serving Maryland, West Virginia, the District of Columbia, and Connecticut, providing clinical data exchange, ENS, PDMP, and analytics. Operates under a comparable statutorily enabled, multi-state governance model and offers the same core suite of services as CyncHealth.
• Indiana Health Information Exchange (IHIE): IHIE is one of the largest and longest-running state/regional HIEs in the U.S., connecting hospitals, providers, and payers across Indiana with clinical data exchange and analytics services — a near-perfect comparable to CyncHealth's Nebraska operation in scale, nonprofit structure, and service mix.
• Michigan Health Information Network Shared Services (MiHIN): MiHIN is Michigan's statewide HIE, designated under state law, providing clinical exchange, event notifications, and Active Care Relationship Service (ACRS). Directly comparable to CyncHealth in statutory designation, multi-stakeholder governance, and core service offering.

Broad incumbents

• Epic (Carequality / Care Everywhere): Epic's Carequality and Care Everywhere networks enable cross-EHR clinical exchange across thousands of hospitals and provider organizations. Comparable as a broad interoperability incumbent whose embedded, EHR-native exchange capability competes with state HIE routing for many health system use cases.
• eHealth Exchange: eHealth Exchange is the largest query-based health information network in the U.S., connecting federal agencies (VA, DoD, CMS) and a national network of HIEs and providers — CyncHealth itself connects via eHealth Exchange. Comparable as a national-level interoperability backbone and a potential alternative/partner as TEFCA matures.

Emerging players

• Health Gorilla: Health Gorilla is a for-profit QHIN and clinical data exchange platform that aggregates records from national labs, HIEs, and EHRs via FHIR APIs. Comparable to CyncHealth in the data-aggregation/clinical-exchange layer but competes as a venture-backed, national-scale alternative rather than a state-designated HIE.
• Particle Health: Particle Health operates a national clinical data API platform pulling from HIEs and EHRs nationwide to serve payers, providers, and digital health companies. Competes with CyncHealth in the multi-state clinical data aggregation layer, particularly for payer and digital health use cases.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/cynchealth

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Subsidiaries6 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about CyncHealth