BrainMD

What BrainMD does

BrainMD is a US-based, direct-to-consumer nutritional supplement company that develops and markets doctor-formulated products positioned for brain health, cognitive performance, mood, sleep, and adjacent wellness use cases. The company is founded and led by Dr. Daniel G. Amen, MD, a double board-certified psychiatrist and 20-time national bestselling author, and is informed by more than 30 years of brain imaging research conducted at Amen Clinics, which houses a database of over 300,000 brain scans. A Medical Advisory Board of 60+ physicians and a named Chief Science Officer (Nicole Avena, PhD) provide clinical and scientific oversight for product formulation, with at least one product (Smart Creatine+) carrying NSF certification. The catalog spans more than 20 SKUs across categories including Focus & Clarity, Stress & Mood, Sleep, Energy, Foundational Health, Memory & Brain Aging, Superfoods, Gut Health, Fitness, and gender- and age-specific lines for women, men, and kids/teens, with unit pricing in the $14.95–$51.95 range.

The core technical differentiator is the proprietary Brain Type Assessment, a 16-category personalization quiz that maps individual respondents to tailored supplement recommendations, supported by an integrated ecosystem including Amen Clinics, Amen University, and the Change Your Brain Foundation. Products are sold primarily through the owned brainmd.com e-commerce storefront with a Subscribe & Save subscription offering up to 25% off plus free shipping, supplemented by a Build Your Bundle tool (up to 20% off), a wholesale partnership program, and an affiliate channel. BrainMD is HSA/FSA eligible and offers free trials to reduce purchase friction, with a measured reliance on content-led acquisition including the "Change Your Brain Every Day" podcast and TikTok virality around products such as Happy Saffron Plus and Smart Creatine+.

BrainMD is a privately held, founder-owned company operating solely in the United States, with 11–50 employees headquartered in Arlington, VA (operations tied to a 949 area code). It has no institutional funding, no disclosed M&A activity, and no regulatory actions on record. The company competes within a North America brain health supplements market projected to grow from $3.0B in 2026 to $5.3B by 2033 at an 8.4% CAGR.

Name

BrainMD

Legal name

BrainMD

Website

https://brainmdhealth.com

Company type

Private

Founded year

1990

Operating status

Operating

Headcount range

11–50 employees

Short description

BrainMD is a US-based, direct-to-consumer supplement company that sells doctor-formulated brain health products across memory, mood, sleep, focus, and fitness categories. Founded by Dr. Daniel Amen, the company leverages Amen Clinics' 300,000+ brain scan database and sells primarily through its e-commerce site with a Subscribe & Save subscription model.

Ownership category

akta.pro rank

Product category

Brain Health Supplements

NAICS

Medicinal and Botanical Manufacturing (325411)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro primary industry

Healthy Aging & Cognitive Support Supplements (CRADAGAM)

akta.pro secondary industry

Sleep, Stress & Mood Support (HLAIADAG)

Keywords

• Brain health supplements
• Cognitive wellness supplements
• Memory support supplements
• Nutraceutical direct-to-consumer
• Mood focus supplements

Headquarters

HQ city

Arlington

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Marketing or Sales, Technology or R&D, Personnel, Operations, Infrastructure

Revenue model

1. Direct Product Sales: One-time purchases and subscription-based sales of brain health supplements through the company's e-commerce platform. Subscription model (Subscribe & Save) offers up to 25% discount plus free shipping, providing recurring revenue from repeat customers.
2. Wholesale & Partnership: Wholesale partnership program allowing third-party retailers to stock and sell BrainMD products, generating bulk transaction revenue.
3. Affiliate Program: Referral-based revenue through affiliate partners who earn commissions for driving sales to the e-commerce platform.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels8 records

Core offering

BrainMD develops and sells science-backed nutritional supplements formulated to support brain health, including memory, focus, mood, sleep, energy, and foundational wellness. Formulas are developed by founder Dr. Daniel Amen and a 60+ MD Medical Advisory Board, informed by 300,000+ brain scans from Amen Clinics. Products are sold direct-to-consumer via an owned e-commerce storefront with subscription (Subscribe & Save) and bundle options.

Product overview

BrainMD is a direct-to-consumer brain health supplement company offering a portfolio of doctor-developed, clinically backed nutritional supplements. The core offering consists of individual products across categories including Focus & Clarity, Stress & Mood, Sleep, Energy, Foundational Health, Memory & Brain Aging, Superfoods, Gut Health, Fitness, and specialized formulas for Women's, Men's, and Kids' health. Key products include Happy Saffron Plus (mood/cognition), Omega-3 Power (foundational brain health), Smart Creatine+ (cognitive and athletic performance), NeuroVite Plus (multivitamin), and Peak Energy (daily energy support). The company also provides personalized assessment tools (Brain Health Assessment, Stress Quiz, Sleep Quiz), subscription services (Subscribe & Save up to 25% off), and bundle building tools. Products are available as capsules, softgels, gummies, and powders. Founded by Daniel G. Amen, MD, BrainMD is backed by 30+ years of research, 60+ physicians, and 300,000+ brain scans from Amen Clinics.

Differentiator

Problem solved

Functional benefit

Products and services

• Happy Saffron Plus TikTok-viral saffron-based supplement supporting mood, memory, focus, and libido. Clinically shown to improve mood, memory, and sexual function, with 5x more absorbable saffron extract than leading brands. Targeted at adults seeking mood and cognitive support.
• Happy Saffron Plus Gummies Sugar-free gummy version of the Happy Saffron Plus formula offering mood, memory, stress, and libido support in a gummy format for consumers preferring chewables over capsules.
• Omega-3 Power High-potency omega-3 supplement providing 5x more omega-3s than leading brands. A best-selling foundational brain health product for daily cognitive and cardiovascular support.
• Smart Creatine+ NSF Certified instantized creatine monohydrate formula designed to support both athletic performance and cognitive function. Marketed as a clean creatine for mind and muscle.
• NeuroVite Plus Multivitamin Advanced brain-boosting multivitamin formulated by Dr. Daniel Amen with clinical-grade ingredients for comprehensive brain health support.
• Taurine Longevity amino acid supplement supporting brain health and healthy aging through cellular-level benefits and brain signaling.
• Smart Magnesium Triple-form magnesium supplement providing total body support including brain health, relaxation, and stress management.
• Smart Relief Fast-acting supplement for aches and discomfort relief formulated with brain-health optimization in mind.
• PreBrainBiotics Science-backed 2-in-1 prebiotic and fiber formula supporting gut-brain axis health, mental clarity, and digestion.
• Put Me To Sleep Naturally Chewables Sleep support chewable delivering a gentle melatonin dose plus calming nutrients to help users fall asleep faster and achieve restful sleep.
• Peak Energy Daily energy supplement blend supporting mental clarity, stamina, and cellular energy without a crash. Used by Dr. Amen as his personal morning supplement.
• Smart Electrolytes Electrolyte powder supporting hydration with brain-nourishing nutrients, marketed for taste and cognitive hydration benefits.
• Smart Mushrooms Functional mushroom supplement supporting mental acuity and cognitive performance. Used daily with meals or in smoothies.
• Brain & Body Power MAX Comprehensive supplement combining brain and body health support with 'Love Your Brain' branding for daily cognitive and physical wellness.
• BRIGHT MINDS Memory Multivitamin Memory-focused multivitamin formulated to address memory problems, brain fog, and support overall cognitive function during aging.
• Advanced Blood Flow Supplement supporting cerebral circulation and blood flow for enhanced brain performance and cognitive function.

Quantifiable outcome

• Over 10 Million Happier Days reported by customers using TikTok-viral Happy Saffron Plus formula
• +3 more outcomes

Named customers7 records

Segments7 records

Ideal customer profiles7 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Three partnerships are on record, tiered core and minor.

• Amen ClinicscoreStrategic or Co-development PartnerRelated entity founded by Dr. Daniel Amen. Home to the world's largest database of brain scans (300,000+ scans) related to behavior. Provides clinical research foundation and data insights that inform BrainMD product development.
• Amen UniversitycoreStrategic or Co-development PartnerEducational platform founded by Dr. Daniel Amen. Extends brain health education and training, potentially driving awareness and customer acquisition for BrainMD products.
• Change Your Brain FoundationminorStrategic or Co-development PartnerNon-profit foundation founded by Dr. Daniel Amen focused on brain health education and advocacy. Supports BrainMD's mission and brand positioning in brain health.

Scale indicators7 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Onnit: Direct-to-consumer supplements and nootropics brand selling cognitive performance products (Alpha BRAIN) through a subscription/owned storefront model. Closely comparable to BrainMD in DTC brain health supplements positioning, subscription mechanics, and influencer-driven brand building.
• Life Extension: Long-standing clinically positioned supplement brand with deep brain, memory, and mood support SKUs. Comparable to BrainMD in science-backed positioning, broad cognitive health catalog, and DTC/online channel mix.
• Thorne: Premium practitioner-grade supplement brand offering brain, mood, sleep, and cognitive health products. Comparable to BrainMD on doctor-developed positioning, premium pricing, and clinically tested formulations.
• Mind Lab Pro (by Performance Lab): Nootropic supplement brand positioned for cognitive performance and memory, sold DTC with subscription. Directly comparable to BrainMD on the brain/cognition supplement focus, although narrower SKU breadth.

Emerging players

• Qualia (Neurohacker Collective): Premium nootropic stack brand built on systems-based neuroscience formulation. Comparable to BrainMD on brain-targeted supplements and premium positioning, but with a more research-engineering brand identity rather than a clinician-founder brand.
• Thesis: DTC personalized nootropics brand using assessments to drive supplement customization. Comparable to BrainMD's brain-type quiz personalization approach but focused exclusively on cognitive performance blends.
• HVMN (formerly Nootrobox): DTC nootropics and biohacking brand targeting cognitive performance and mood. Comparable to BrainMD on DTC cognitive supplements, though operating at smaller scale and narrower product line.
• Ritual: DTC supplement brand with subscription model, clinically backed formulations, and traceable ingredients. Comparable to BrainMD on subscription DTC mechanics and clinical positioning, though focused on multivitamins and women's health rather than brain health specifically.

Broad incumbents

• Nature's Way: Large established supplement brand with brain/memory/mood SKUs sold across mass retail and DTC. Comparable to BrainMD on cognitive supplement offerings, but as a broad incumbent with significantly wider distribution and lower clinical-boutique positioning.
• NOW Foods: Major supplement manufacturer with extensive brain, mood, and cognitive health product lines sold via wholesale, retail, and DTC. Comparable to BrainMD on cognitive supplement categories, but competes as a value-priced incumbent rather than a premium clinician-led brand.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/brainmdhealth
• YouTubeyoutube.com/c/brainmdhealth
• Facebookfacebook.com/BrainMDHealth
• LinkedInlinkedin.com/company/brainmd
• Instagraminstagram.com/brainmdhealth
• TikToktiktok.com/@brainmdhealth
• Pinterestpinterest.com/brainmdhealth

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about BrainMD