Mantality Health

What Mantality Health does

Mantality Health is a physician-led men's health clinic operating nine physical locations across seven states in the Midwest and Northeast (Missouri, Iowa, Wisconsin, Nebraska, Michigan, Ohio, and Pennsylvania), with a Chesterfield, Missouri headquarters. Founded in 2014, the company provides medically supervised testosterone replacement therapy (TRT) as its core offering, supplemented by a broader men's health and longevity portfolio including peptide therapy (Sermorelin and CJC-1295/Ipamorelin HGH secretagogues), daily tadalafil for erectile dysfunction, NAD+ IV therapy and injections, IV infusion services (Wellness, Sick, and Hangover formulations), and at-home hormone test kits. Every protocol is grounded in a 50+ biomarker comprehensive blood panel and adjusted quarterly through continuous physician-led monitoring rather than automated refills.

The company operates a hybrid care model combining in-person consultations at its physical clinics with 100% telehealth follow-up capability after initial labs, and ships prescribed medications discreetly to patient doors nationwide. Underlying clinical infrastructure includes partnerships with FDA-registered compounding pharmacies (Olympia Pharmaceuticals in Orlando, FL and Genesis Pharmacy Services in St. Louis, MO) sourcing bio-identical hormones and peptides, and the company operates under LegitScript certification, HIPAA compliance, and FDA guidelines for controlled testosterone substances.

Mantality runs a cash-pay model without insurance billing, accepting HSA and FSA payments and using transparent flat-monthly subscription pricing for ongoing TRT and peptide protocols, with separately priced one-time IV infusions ($119–$279). Marketing is primarily content- and SEO-driven targeting searches for TRT and hormone therapy, supplemented by direct booking funnels and Google review-driven social proof. In March 2025, Mantality Health was acquired by Agentis Longevity, a healthcare platform backed by private equity firm Shore Capital Partners, with the stated intent to standardize protocols and scale Mantality's clinic model nationally across Agentis's broader longevity platform. Mantality continues to operate as a brand within Agentis Longevity following the transaction.

Name

Mantality Health

Legal name

Mantality Health

Website

https://mantalityhealth.com

Company type

Private

Founded year

2014

Operating status

Acquired

Headcount range

11–50 employees

Short description

Physician-led men's health clinic operating 9 Midwest and Northeast locations, offering medically supervised testosterone replacement therapy, peptide therapy, tadalafil, NAD+ IV therapy, and related cash-pay men's longevity services to individual male patients since 2014.

Ownership category

akta.pro rank

Product category

Men's Hormone Therapy & Wellness Clinics

NAICS

Home Health Care Services (62161)

SIC

Services-Offices & Clinics Of Doctors Of Medicine (8011)

akta.pro primary industry

Men’s Health Prescribing + Pharmacy Delivery Platforms (HLALAIAJ)

akta.pro secondary industry

Male Reproductive & Sexual Medicine (Andrology) (HLAKAOAD)

Keywords

• Testosterone replacement therapy
• Hormone optimization
• Men's health clinic
• Peptide therapy
• IV infusion therapy

Headquarters

HQ city

Chesterfield

HQ country

United States

HQ region

North America

Offices9 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Supply Chain, Infrastructure

Revenue model

1. Monthly Subscription (TRT/Hormone Therapy): Transparent flat-monthly fee model for ongoing testosterone replacement therapy and hormone optimization protocols. Pricing disclosed upfront with no hidden fees or surprise upcharges. Patients work with the same physician throughout care with adjustments based on clinical need rather than sales cycles.
2. IV Infusion Services: One-time or periodic IV infusion services including Wellness ($189), Sick ($279), and Hangover ($119) infusions administered by licensed nurse practitioners.
3. Peptide Therapy: Additional peptide therapy protocols prescribed alongside or independent of TRT for recovery, body composition, and cognitive optimization goals.
4. Erectile Dysfunction Treatment (Tadalafil): Daily tadalafil prescriptions shipped discreetly to patients, described as the most affordable provider of online prescription ED medication in the US.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels5 records

Core offering

Mantality Health is a physician-led men's health clinic that delivers medically supervised testosterone replacement therapy and hormone optimization protocols grounded in 50+ biomarker blood panel diagnostics. The offering is centered on individually prescribed, continuously monitored TRT combined with peptide therapy, daily tadalafil, NAD+ IV/injection therapy, and IV infusions, delivered through a hybrid model of 9 Midwest clinic locations plus telehealth and direct-to-door prescription shipping.

Product overview

Mantality Health is a physician-led men's health and longevity platform offering a unified suite of precision medicine services. The core portfolio centers on Testosterone Replacement Therapy (TRT) as the primary offering, supplemented by Peptide Therapy (HGH secretagogues including Sermorelin and CJC-1295/Ipamorelin), Tadalafil for erectile dysfunction, NAD+ IV/injection therapy, and IV Infusion cocktails (Wellness, Sick, Hangover). All treatments are grounded in comprehensive 50+ biomarker blood panel diagnostics and supervised by board-certified physicians. The company operates a hybrid care model combining in-person clinic visits with telehealth follow-ups, with treatments shipped directly to patients' doors. Services are offered across nine Midwest clinic locations with nationwide shipping capability.

Differentiator

Problem solved

Functional benefit

Products and services

• Testosterone Replacement Therapy (TRT)

Quantifiable outcome

• 94% of men report renewed energy and focus within 60 days
• +3 more outcomes

Named customers6 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Four partnerships are on record, tiered core and minor.

• Agentis LongevitycoreStrategic or Co-development Partner · 18 March 2025Agentis Longevity, a healthcare platform backed by Shore Capital Partners, acquired Mantality Health. The acquisition brings Mantality's network of providers, patient data, and patient-first care model to Agentis Longevity's growing longevity platform. Mantality operates as a brand owned and operated by Agentis Longevity.
• Agenda HealthminorStrategic or Co-development Partner · 18 March 2025M&A advisory firm that facilitated the acquisition of Mantality Health by Agentis Longevity.
• Olympia PharmaceuticalscoreTechnology or IntegrationFDA-registered compounding pharmacy located in Orlando, FL (6700 Conroy Rd, Suite 115, Orlando, FL 32835, 407-673-2222). Source for bio-identical peptides and medications prescribed by Mantality physicians.
• Genesis Pharmacy ServicescoreTechnology or IntegrationCompounding pharmacy located in St. Louis, MO (1876 Craigshire Dr, St. Louis, MO 63146, 314-485-8600). Sources medications including testosterone cypionate for Mantality's TRT protocols.

Scale indicators8 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Hims & Hers Health: Public telehealth platform offering men's TRT, ED medication (sildenafil/tadalafil), and a broad portfolio of wellness products. Directly comparable to Mantality's online TRT + pharmacy delivery model but operates at national scale without brick-and-mortar clinics.
• Ro: Telehealth platform providing men's hormone optimization, ED treatment, and weight management (GLP-1s). Directly competes with Mantality's telehealth + pharmacy delivery layer and has expanded aggressively into hormone therapy, making it a primary competitor for cash-pay patients.
• Cleveland Clinic Men's Health: Academic medical center offering men's health services including hormone evaluation and TRT within a broader urology/endocrinology practice. Represents the integrated incumbent model Mantality competes against for higher-acuity patients.

Direct peers

• Marek Health: Online TRT and hormone optimization platform with comprehensive blood work panels and physician-supervised protocols. Closely comparable to Mantality's clinical positioning, biomarker-driven model, and recurring subscription revenue model.
• Hone Health: Telehealth men's hormone clinic offering TRT with at-home diagnostics and physician oversight. Mirrors Mantality's hybrid in-clinic/telehealth approach with similar cash-pay subscription pricing and outcome-focused marketing.
• Low T Center: Multi-location clinic network specializing exclusively in testosterone replacement therapy. Most comparable to Mantality in operating model (in-person clinic + recurring TRT subscription) and product focus.
• AGELESS Men's Health: Multi-state men's clinic chain focused on testosterone replacement therapy with in-person visits and recurring treatment plans. Direct competitor in the same brick-and-mortar men's hormone space as Mantality.
• TRT Nation: Online TRT provider offering physician-prescribed testosterone therapy with at-home labs and direct-to-door medication delivery. Closely comparable subscription pricing model and cash-pay customer base.
• Defy Medical: Telehealth and clinic-based practice providing hormone replacement therapy, peptide therapy, and wellness treatments for men and women. Comparable clinical protocols, cash-pay model, and longevity-focused positioning.

Emerging players

• Peter Attia / Early Medical-style longevity clinics: Premium concierge longevity practices offering hormone optimization alongside broader healthspan programs. Represents the emerging 'longevity clinic' category Mantality is being rolled up into via Agentis Longevity.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/mantalityhealth
• Facebookfacebook.com/mantalityhealthstlouis
• LinkedInlinkedin.com/company/mantalityhealth

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Mantality Health