PhysioAge

What PhysioAge does

PhysioAge, operating as PhysioAge Systems LLC, is a New York-based health-analytics SaaS company that builds software for biomarker-driven longevity medicine. The platform collects, analyzes, and visualizes patient lab and diagnostic data to produce custom scorecards and reports for physicians and patients. Its technical core is the integration of validated biomarkers of aging — CardioAge, PhenoAge, TruAge, and GlycanAge — with a proprietary PhysioAge Aggregate Age calculation spanning up to 7 biological systems, covering 800+ biomarkers in total. Letter-grade (A through F) scoring and optimal-range referencing (derived from scientific literature rather than conventional normal ranges) are positioned as the clinical differentiators. The product surface consists of the web-based PhysioAge Health Analytics tool, the PhysioAge App on iOS and Android, and a suite of Patient, Physician, and Visit-Summary PDF reports, with an optional Practice Analytics add-on providing practice-wide population views.

PhysioAge is physician-owned, with no disclosed external venture or institutional capital. It was originally developed and validated inside Dr. Joseph Raffaele's clinical practice (Raffaele Medical) before being commercialized to other clinics; the company has been active in longevity medicine since the founder's research program began in 1995 and was spun into a software business in 2008. Revenue is generated primarily through recurring monthly subscriptions starting at $300 per individual user, with no commitment or implementation fee, and secondarily through fee-for-service clinical assessment packages that provider practices build into their service mix. Distribution is split between enterprise direct sales to physicians and clinics and self-serve consumer acquisition through the website, iOS App Store, and Google Play Store.

The firm operates in a narrow and growing niche — longevity and preventive medicine — targeting physicians seeking practice differentiation through biomarker tracking and health-conscious individuals seeking biological-age monitoring. Customer concentration evidence is limited: only Raffaele Medical is named as a customer, the company is founder-led by Dr. Raffaele (Co-Founder and CEO) with co-founder Jerry Fortunato and CTO J. Daniel Powell, and its go-to-market relies heavily on founder-driven thought leadership through the Longevity Insights blog, organic social channels, and recurring PR placements in outlets such as the New York Times, Wired, NPR, and NBC. No certifications, patents, partnerships, integrations, APIs, or regulatory milestones are disclosed in the source data.

Name

PhysioAge

Legal name

PhysioAge Systems LLC

Website

https://physioage.com

Company type

Private

Founded year

2008

Operating status

Operating

Headcount range

11–50 employees

Short description

PhysioAge is a New York-based health-analytics SaaS company offering a biomarker-tracking and longevity-medicine platform to physicians, clinics, and individual subscribers on monthly subscriptions starting at $300.

Ownership category

akta.pro rank

Product category

Health Analytics Software

SIC

Services-Prepackaged Software (7372)

akta.pro primary industry

Remote Diagnostics & Point-of-Care (Connected Testing, Home Lab Devices) (HLACAPAK)

akta.pro secondary industries

Cardiometabolic RPM & Chronic Disease Management (diabetes, hypertension, CHF, obesity) (HLALAFAA), Medication Adherence, Digital Therapeutics & Remote Coaching (condition-specific programs) (HLALAFAF)

Keywords

• Health analytics software
• Biomarker tracking platform
• Biological age assessment
• Longevity medicine platform
• Clinical decision support

Headquarters

HQ city

New York

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Subscription Analytics Platform: Healthcare providers and patients pay recurring subscription fees to access the PhysioAge health analytics platform, including web-based software, the PhysioAge App, patient reports, and physician reports. Pricing starts at $300/month for individual users.
2. Assessment Services: Fee-for-service model where practices offer biomarker assessments as a differentiated service offering, generating revenue from individual patient assessments that can be built into regular service packages.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels5 records

Core offering

PhysioAge provides a web-based health analytics software platform that collects patient biomarker data, generates custom physiological aging scorecards, and delivers both patient-facing and physician-facing reports to support longevity and preventive medicine decision-making. The platform is offered as a subscription to individual patients and licensed to physicians and concierge practices for use in clinical consultations.

Product overview

PhysioAge is a longevity medicine platform consisting of a core Health Analytics web-based software platform and mobile PhysioAge App. The platform integrates Patient Reports, Physician's Reports, and Visit Summaries to enable healthcare providers to track validated biomarkers of aging (CardioAge, PhenoAge, TruAge, GlycanAge), generate letter-graded scorecards, and deliver personalized health recommendations. An optional Practice Analytics module provides practice-wide population health insights. Pricing starts at $300/month with no commitment or investment required.

Differentiator

Problem solved

Functional benefit

Products and services

• PhysioAge Health Analytics Platform
• PhysioAge Mobile App
• Practice Analytics

Quantifiable outcome

• 800+ biomarkers tracked and explained for comprehensive biological age assessment
• +2 more outcomes

Named customers1 record

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability3 records

Feature5 records

Scale indicators2 records

Recent moves4 records

Expansion highlights4 records

Direct peers

• InsideTracker: InsideTracker is a direct competitor offering blood biomarker analytics with personalized recommendations for individuals and corporate wellness programs, addressing the same preventive longevity use cases as PhysioAge through a similar SaaS-plus-D2C model.
• Function Health: Function Health offers comprehensive lab testing with structured longitudinal health insights for consumers, directly competing with PhysioAge's biomarker-driven preventive health analytics and membership model.
• TruDiagnostic: TruDiagnostic provides epigenetic biological age testing (one of the same biomarkers - TruAge - used by PhysioAge) with provider and consumer offerings, making it a tight technical peer in the validated aging biomarker category.
• Elysium Index: Elysium's Index product delivers biological age testing and longitudinal biomarker tracking for consumers, overlapping with PhysioAge's aggregate-age and biomarker scorecard value proposition.
• TallyHealth: TallyHealth sells a biological age test plus personalized longevity program for consumers, competing in the same preventative longevity analytics space that PhysioAge targets through its provider-led model.

Broad incumbents

• Thorne: Thorne is a much larger supplements-and-health-data company with its own at-home biomarker tests (Thorne Healthspan) that sits adjacent to PhysioAge's biomarker analytics offering, drawing on similar consumer longevity demand.
• Human Longevity Inc: Human Longevity Inc. is a broader enterprise longevity-diagnostics player combining genomics, imaging, and biomarker analytics for premium executive health programs, serving as a broader incumbent in the same longevity diagnostics category.
• Fountain Life: Fountain Life operates a network of longevity-focused clinics offering advanced diagnostics and biomarker-driven health optimization, making it comparable as a broader incumbent in the provider-side longevity medicine market.

Emerging players

• Lifeforce: Lifeforce is a digital healthspan membership combining at-home biomarker testing, supplements, and clinician consultations - an emerging consumer longevity platform that overlaps with PhysioAge's biomarker-tracking core.
• Biopeak: Biopeak is a newer healthspan platform offering advanced biomarker testing and personalized longevity programs for individuals, making it a relevant emerging peer in preventive longevity analytics.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/physioage-medical-group
• Instagraminstagram.com/raffaelemd

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about PhysioAge