What Pellecome does

Pellecome LLC is a US-based, founder-owned private company that develops, manufactures, and distributes bio-identical hormone replacement therapy (BHRT) products and a patented pellet insertion device for the anti-aging and wellness medicine market. The company was established as a corporate entity in 2019 around clinical work Dr. Enrique G. Jacome had been conducting since 1995, with a formal BHRT pellet focus since 2002. Its core product is the Re3 Advanced Pellet Delivery System — a patented mechanical device with separate male and female variants, a precision scalpel, and funnel technology — paired with proprietary Re3 pellet formulations of estradiol (10-25mg), progesterone (50-200mg), and testosterone (25-300mg) manufactured under strict quality standards.

The company operates a B2B2C model, selling the Re3 device, pellets, supplements, and a two-part HCP training program (online didactic plus hands-on proctoring) directly to physicians, nurse practitioners, and physician assistants who incorporate BHRT into their practices. Patients are reached through the Find a Provider directory on pellecome.com and through an online shop for the company's 20+ nutritional supplements organized across six clinical categories. Distribution is nationwide USA, with revenue generated from device cases (Re3 Male $650/case, Female $550/case), needle packs, procedural kits, pellet prescriptions, wholesale supplements, training fees, and licensing of the Re3 system — though no public pricing exists for pellets, supplements, or training.

Pellecome monetizes through a recurring consumable model anchored by pellet reinsertion cadences of 3-4 times per year per patient, complemented by a branded educational ecosystem (Pellecome FIT program, virtual practice workshops, A4M conference presence, podcast features) and a patient-facing brand-building effort (Instagram presence, Dolvett Quince partnership). The company holds US patents on the Re3 device and registered trademarks for Pellecome FIT and The Power of the Consult, but discloses no funding rounds, no certifications, no formal compliance programs, and no AI/ML capabilities.

Name

Pellecome

Legal name

Pellecome LLC

Website

https://pellecome.com

Company type

Private

Founded year

2002

Operating status

Operating

Headcount range

1–10 employees

Short description

Pellecome LLC sells a patented Re3 pellet delivery device, bio-identical hormone pellets, and a 20-SKU supplement line to US healthcare providers who offer BHRT and weight-loss services to men and women through a B2B2C model.

Ownership category

akta.pro rank

Product category

Bioidentical Hormone Replacement Therapy Devices and Pellets

NAICS

Pharmaceutical and Medicine Manufacturing (3254), Medical Equipment and Supplies Manufacturing (3391), Food (Health) Supplement Retailers (456191)

SIC

Pharmaceutical Preparations (2834), Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842)

akta.pro primary industry

Women’s Health Supplements (Prenatal, Menopause, Hormonal) (CRADAGAK)

akta.pro secondary industry

Specialty Condition Supplements (Sleep, Stress, Heart, Joint, Gut, Immunity) (CRADAGAE)

Keywords

• Bioidentical hormone therapy
• Pellet insertion devices
• Compounded hormone pellets
• BHRT provider training
• Hormone optimization supplements

Headquarters

HQ city

Randolph

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Marketing or Sales, Personnel, Technology or R&D

Revenue model

1. Medical Device Sales: Sale of the Re3 Advanced Pellet Delivery System kits to healthcare providers. Devices are sold in cases of 10 units for males ($650) and females ($550), with additional needle packs and procedural kits available. This is a recurring revenue stream as providers need to restock supplies.
2. Hormone Pellet Prescriptions: Bio-identical hormone pellets (estradiol, progesterone, testosterone) sold to HCPs for implantation in patients. Pellets are customized to patient dosing needs with multiple strength options.
3. Nutritional Supplements: Sale of branded supplements across six categories: Inflammation, Stress & Cortisol, Hormone Imbalance & Decline, Gut Integrity & Dysbiosis, Infectious & Immune, and Fat Burning/Blood Sugar Control. Products include DIM I3C, DHEA, Vitamin D3 & K2, Pregnenolone, Peptides, and others. Sold in multi-bottle packages at wholesale to HCPs.
4. HCP Training & Licensing: Revenue generated from comprehensive BHRT pellet insertion training programs for healthcare providers. Training includes online didactic learning, hands-on training with physician proctor and live patient models, practice management support, pellet dosing calculator, on-site staff training options, and digital marketing solutions.
5. Technology Licensing: Licensing of Pellecome's patented pellet insertion device, proprietary formulations, and business processes to healthcare providers looking to build a BHRT and weight loss business. Includes no contracts and no non-competes.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels10 records

Core offering

Pellecome sells a patented Re3 Advanced Pellet Delivery System, bio-identical hormone pellets (estradiol, progesterone, testosterone), and a suite of nutritional supplements to licensed healthcare providers for use in bio-identical hormone replacement therapy (BHRT). The company also provides HCP training programs, practice management support, and licensing of its device and processes. Patients access the therapy through trained providers listed in the Find a Provider directory and can purchase supplements directly through the online shop.

Product overview

Pellecome is a bioidentical hormone replacement therapy (BHRT) company offering a comprehensive ecosystem centered around its patented Re3 Advanced Pellet Delivery System and Re3 Advanced Pellet Formulations. The core offering consists of the Re3 device (a medical instrument for pellet insertion) paired with hormone pellets containing estradiol, progesterone, and testosterone in multiple dosage strengths. Beyond the delivery system, Pellecome offers the Pellecome FIT customized medical treatment program and over 20 different nutritional supplements organized into categories: Hormone Imbalance & Decline, Stress & Cortisol, Fat Burning/Blood Sugar Control, Gut Integrity & Dysbiosis, Inflammation, and Infectious & Immune. Key supplements include DIM/I3C, DHEA, Vitamin D3 & K2, Pregnenolone, Peptides, BrainFit, ThyroFit, MagFit, Craving Control, CardioFit, GlucoFit, and various probiotic formulations. The company also provides HCP training programs for pellet insertion techniques. The products work together as an integrated approach to hormone optimization and wellness, with pellets providing sustained hormone delivery and supplements supporting overall metabolic, gut, and hormonal health.

Differentiator

Problem solved

Functional benefit

Brands

• Re3 Advanced Pellet Delivery System: Patented medical device for BHRT pellet insertion designed to make the procedure easier, safer, and more reliable for healthcare providers and patients.
• Pellecome FIT
• The Power of the Consult

Products and services

• Re3 Advanced Pellet Delivery System Patented medical device for inserting bio-identical hormone replacement (BHRT) pellets, designed to make pellet insertion easier, safer, and more reliable for healthcare providers. Available in male and female versions, with an insertion tool, precision scalpel, and funnel technology.
• Pellecome FIT Customized medical treatment program based on an individual's metabolic and hormonal needs to support optimal health, recovery, and performance. Integrates hormone therapy with supplementation and lifestyle guidance.
• Re3 Advanced Pellet Formulations (Estradiol, Progesterone, Testosterone) Bio-identical hormone pellets manufactured under strict quality standards. Estradiol (10, 15, 20, 25 mg), progesterone (50, 100, 200 mg), and testosterone (25, 50, 100, 200, 300 mg) pellets provide predictable dosing and reliable therapeutic outcomes with no degradation.
• HCP BHRT Training Program Comprehensive two-part training workshop for healthcare providers combining online didactic learning with hands-on training led by a physician proctor using live patient models. Includes practice management support, a pellet dosing calculator, on-site staff training options, and digital marketing solutions.
• Pellecome Device and Process Licensing Licensing of Pellecome's patented pellet insertion device, proprietary Re3 formulations, and business processes to healthcare providers seeking to build a BHRT and weight loss business. No contracts and no non-competes.
• Craving Control Supplement Combines clinically studied extracts of Piper betle leaf and Dolichos biflorus seed plus acetyl-L-carnitine to support metabolic hormones (adiponectin, leptin, ghrelin) for appetite and fat metabolism control.
• CardioFit Supplement Formula combining berberine and alpha lipoic acid (ALA) to maintain heart function, metabolism, antioxidant status, and lipid and glucose levels for cardiometabolic health.
• GlucoFit Supplement Natural synergistic formula for maintaining balanced blood sugar through enhanced cellular level signaling, containing five targeted ingredients.
• MitoFit Supplement Purified dairy-free source of immunoglobulin G (IgG) providing 1,150mg per serving to maintain healthy intestinal immune system and bind microbes and toxins.
• L-Glutathione Supplement Master antioxidant supplement providing 250mg dose of reduced glutathione (GSH) for immune function, detoxification, and protection against oxidative stress.
• Pure Fish Oil Supplement High-concentration fish oil providing 820mg of EPA, DHA, and DPA per soft gel as re-esterified triglycerides for cardiovascular, brain, skin, and joint health.
• Turmeric Supplement Anti-inflammatory supplement for inflammation management and overall wellness support.
• Gut Balance Probiotic Supplement Probiotic formula delivering seven proven strains to promote healthy gut microflora, protect intestinal integrity, and boost immune function with Saccharomyces boulardii.
• GastroMover Supplement Formula for relief of occasional constipation using Cape aloe to affect colon peristalsis and accelerate intestinal passage.
• UroGyn Balance Probiotic Supplement Unique probiotic formula designed to maintain healthy vaginal microflora and support urogenital health.
• Vitamin D3 & K2 Supplement Liquid supplement providing D3 25mcg (1,000 IU) and K2 10mcg per serving for BHRT, cardiovascular, and musculoskeletal health support.
• BrainFit Supplement Cognitive support supplement designed for hormone imbalance and decline, supporting brain health and mental function.
• DHEA 25mg Supplement Steroid hormone precursor supplement derived from wild yam, providing 25mg per capsule to maintain healthy hormone levels and support stress response.
• DIM/I3C Supplement Targeted supplement combining I3C and DIM to support proper estrogen metabolism, breast and prostate health.
• MagFit Magnesium Supplement Magnesium supplement providing three unique forms of highly absorbed magnesium to ensure maximum absorption of this important macromineral.
• ThyroFit Thyroid Support Supplement Comprehensive thyroid support formulation with L-tyrosine and iodine to support thyroid hormones T4 and T3 production.
• B Fit B-Complex Supplement Balanced B complex supplement containing eight essential B vitamins with choline, inositol, and folate as Quatrefolic 5-MTHF for optimal methylation.
• Stress Support - Energizing Supplement Blend of adaptogenic botanicals and adrenal concentrate formulated to strengthen stress response and support healthy energy levels while balancing cortisol and DHEA.
• Power T Booster Supplement Nootropic blend with adaptogenic botanicals and nutrients to counteract effects of daily stress, improve mental performance, and support healthy energy levels.
• Pregnenolone Supplement Hormone precursor supplement with 10mg per scored quick-dissolved tablet for hormonal balance, brain function, and stress response support.

Quantifiable outcome

• Over 30,000 pellet insertions performed by founder Dr. Jacome since 1995
• +3 more outcomes

Named customers9 records

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• BioTE Medical: BioTE is the largest direct competitor in BHRT pellet therapy, offering a patented subcutaneous pellet insertion method, training programs for providers, and bioidentical hormone pellets. Operates a substantially larger national provider network than Pellecome.
• SottoPelle: SottoPelle provides BHRT subcutaneous pellet therapy with proprietary dosing and provider training programs. Directly competes with Pellecome in the same pellet-based hormone replacement category serving anti-aging and wellness providers.
• Evexias Health Solutions: Evexias offers BHRT pellet therapy, provider training, and a portfolio of wellness products to functional medicine practitioners. Targets the same anti-aging/wellness HCP customer base as Pellecome.
• Defy Medical: Defy Medical is a telehealth and clinic-based provider of hormone optimization including BHRT pellets, serving both providers and patients directly. Comparable in combining device/protocol training with patient-facing services.
• Hormone Therapeutics: Hormone Therapeutics offers bioidentical hormone replacement therapy including pellet implants, training, and provider support — overlapping directly with Pellecome's offering to wellness-focused HCPs.

Emerging players

• Marek Health: Marek Health is a direct-to-consumer men's hormone optimization platform offering testosterone and related therapies. Partial overlap with Pellecome's male BHRT segment, but operates a digital-first model rather than provider-network distribution.
• AgelessRx: AgelessRx is a telehealth platform offering hormone optimization, peptides, and longevity therapies. Adjacent competitor targeting similar patients but through a consumer-direct telehealth model rather than HCP channel.

Others

• Thorne: Thorne is a premium nutritional supplement brand with practitioner-channel distribution, overlapping with Pellecome's supplement business and HCP sales motion though not its core BHRT pellets or delivery device.
• Designs for Health: Designs for Health is a practitioner-channel nutritional supplement company with overlapping HCP customer base. Comparable in selling professional-grade supplements through licensed providers, though without BHRT pellets or device offering.
• Wedgewood Pharmacy: Wedgewood Pharmacy is a 503A/503B compounding pharmacy that supplies custom-compounded bioidentical hormone preparations to providers. Functions as a potential upstream supplier/competitor for Pellecome's pellet formulations.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• Instagraminstagram.com/pellecomellc
• Xx.com/PellecomeLLC
• Facebookfacebook.com/PellecomeLLC

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Pellecome