Casa de Sante

What Casa de Sante does

Casa de Sante is a physician-founded health brand that develops and sells Low FODMAP certified dietary supplements, GLP-1 companion products, and clinical skincare targeting individuals with IBS, SIBO, sensitive digestive systems, GLP-1 medication users, and women in menopause transition. Founded in 2017 by Dr. Onikepe Adegbola (Dr. Onyx), a Johns Hopkins-trained MD PhD with over 20 years of clinical and research experience, the company operates as a private, founder-owned e-commerce business headquartered in Ambler, Pennsylvania. The portfolio spans digestive enzymes, protein powders, probiotics, multivitamins, herbal laxatives, hormone balance supplements, and GLP-1-specific bundles, with all products certified Low FODMAP by the FODMAP Friendly program and third-party tested for heavy metals by ISO-accredited labs (Summit Labs, Merieux NutriSciences) with published Certificates of Analysis.

The company has built a proprietary supplement formulation platform anchored on the ProHydrolase enzyme blend delivering 3x faster protein absorption, cGMP manufacturing standards, and a digital ecosystem comprising the GLP-1 Support iOS app (launched 2025), the 9-Week Gut Health Navigator App, AI-powered tools (Low FODMAP AI Chef, Lab Results AI, Gut Health Chatbot), and a content library of 8,000+ blog articles and four Substack newsletters. Revenue is generated primarily through direct-to-consumer e-commerce on casadesante.com and Amazon marketplace storefronts, supplemented by subscription meal plans via the LivingPlateRx partnership ($9.99/month), mobile app sales ($29 entry point), and a healthcare provider referral channel. Pricing spans $22.99 entry-level supplements to $686.59 comprehensive protocol bundles, with HSA/FSA eligibility via TrueMed and international storefronts supporting Australia, Canada, New Zealand, and the United States. The brand reports 4.8/5 customer satisfaction across 281 reviews and states that over 10,000 patients trust Dr. Onyx's formulations.

Name

Casa de Sante

Legal name

Casa de Sante

Website

https://casadesante.com

Company type

Private

Founded year

2017

Operating status

Operating

Headcount range

11–50 employees

Ownership category

akta.pro rank

Product category

Dietary Supplements

NAICS

Food (Health) Supplement Retailers (456191), Food Manufacturing (311)

SIC

Food And Kindred Products (2000), Miscellaneous Food Preparations & Kindred Products (2090)

akta.pro primary industry

Probiotics & Digestive Health Supplements (CRADAGAF)

akta.pro secondary industries

Medical Nutrition & Meal Replacement (RTD, Bars, Powders) (CRADAGAN), Gut Health & Digestive Nutrition (IBS, GERD, Elimination Diets) (HSADAFAH)

Keywords

• Low FODMAP supplements
• Digestive health products
• GLP-1 support supplements
• IBS dietary solutions
• Physician-formulated nutrition

Headquarters

HQ city

Ambler

HQ country

United States

HQ region

North America

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Marketing or Sales, Technology or R&D, Operations

Revenue model

1. Direct E-commerce Product Sales: Casa de Sante sells dietary supplements (digestive enzymes, protein powders, probiotics, multivitamins), GLP-1 support products, clinical skincare, hormone balance supplements, and digital products (eBooks, meal plans, mobile apps) directly through its casadesante.com e-commerce storefront. Products are sold as one-time purchases or through bundled protocol packages. The company also maintains an Amazon storefront for product sales.
2. Subscription Meal Plans: Casa de Sante offers dietitian-prepared meal plans through LivingPlateRx partnership at $9.99/month, with a free 3-day trial. Plans cover Low FODMAP, SCD, AIP, Elimination Diet, Low Histamine, PCOS, Keto, and other dietary protocols.
3. Digital Products and Mobile Apps: Sale of eBooks, educational guides, and mobile apps such as the 9-Week Gut Health Navigator App at $29.00 and various diet-specific apps for thyroid support, intermittent fasting, GERD, and autoimmune protocols.
4. Amazon Marketplace Sales: Casa de Sante maintains Amazon storefront presence selling Low FODMAP food products including breads, pasta, snacks, sauces, and keto items alongside supplements.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels8 records

Core offering

Casa de Sante manufactures and sells physician-formulated, Low FODMAP Certified dietary supplements (digestive enzymes, protein powders, probiotics, multivitamins, collagen) targeted at individuals with IBS, SIBO, and sensitive digestive systems, along with GLP-1 medication companion products addressing nausea, constipation, and muscle preservation for users of Ozempic, Wegovy, and Mounjaro. The company supplements its physical product line with digital tools including the iOS GLP-1 Support App, AI Meal Planner, Lab Results AI, and dietitian-prepared meal plans delivered via a LivingPlateRx partnership.

Product overview

Casa de Sante is a physician-founded health brand (Dr. Onikepe Adegbola, MD PhD) specializing in Low FODMAP certified supplements and GLP-1 medication support products. The core offering consists of dietary supplements (digestive enzymes, protein powders, probiotics, multivitamins, collagen peptides) all certified Low FODMAP for IBS/SIBO patients. The company has expanded into GLP-1 companion products addressing nausea, constipation, and muscle preservation for Ozempic/Wegovy/Mounjaro users. Supporting the product portfolio are digital tools including the GLP-1 Support App (iOS), Low FODMAP AI Chef, meal planning services, and educational content (ebooks, guides, blogs). The brand also offers hormone balance/menopause products and clinical skincare targeting GLP-1 weight loss side effects.

Differentiator

Problem solved

Functional benefit

Products and services

• FODMAP Digestive Enzymes Low FODMAP certified digestive enzyme blend containing Alpha Galactosidase, Lactase, Bromelain, and Cellulase to break down FODMAPs and reduce bloating, gas, and abdominal discomfort for individuals with IBS, SIBO, and sensitive digestive systems. Priced at $29.99 USD.
• Elemental Protein Powders Low FODMAP Certified protein powders including Whey WPI Protein Isolate (fortified with ProHydrolase enzymes for 3x better protein absorption) and Plant-Based Vegan Protein Powder (pea and rice protein), Elemental Diet compliant. Priced up to $57.99.
• Advanced Probiotic & Prebiotic Synbiotic formulations combining probiotics and prebiotics for daily gut health support and microbiome balance, Low FODMAP certified, priced up to $45.99.
• Vitamin & Mineral Gummies Daily essential nutrition supplements in gummy form, formulated to be Low FODMAP and suitable for GLP-1 medication users, priced at $22.99 USD.
• GLP-1 MD Skincare Clinical skincare products addressing 'Ozempic face' and skin changes during GLP-1 weight loss treatment. Includes HydraLift Collagen Complex, Needle-Free Wrinkle Smoother, and comprehensive skincare protocol kits. Individual items range from $87.49 to $151.89; bundles range from $226.59 to $686.59.
• Hormone Balance & Menopause Products Products for perimenopause and menopause support including the Menopause Gut-Hormone Reset Protocol at $67.89 and Menopause Wellness Guide workbook at $39.99, developed by Dr. Onyx MD PhD.
• Herbal Laxative / Colon Cleanse 15-day herbal colon cleanse for gentle motility support, formulated to be Low FODMAP and gut-friendly for individuals with IBS-C and GLP-1 users experiencing constipation.
• GLP-1 Success System Bundles Doctor-designed daily routine bundles combining protein shakes, digestive enzymes, multivitamins, probiotics, and colon cleanse products for comprehensive GLP-1 medication support. Available in Vegan, Whey Vanilla, and Whey Chocolate variants, priced at $179.39.
• GLP-1 Support Mobile App iOS mobile application for GLP-1 medication users featuring personalized nutrition plans, adaptive workout programs, medication tracking with reminders, and AI-powered guidance. Built by Dr. Onyx MD PhD.
• 9-Week Gut Health Navigator App Casa de Sante's 9-week elimination and reintroduction Low FODMAP diet app to guide users through the FODMAP protocol, priced at $29.00 USD.
• Dietitian Meal Plans Subscription Dietitian-prepared meal plans including Low FODMAP, SCD, AIP, Elimination Diet, Low Histamine, PCOS, Diabetes, Keto, and 30+ other specialized protocols, delivered via partnership with LivingPlateRx at $9.99/month with a free 3-day trial.
• Books & eBooks Digital cookbooks and guides including The Complete Low-Fodmap IBS Relief Cookbook, SIBO nutritional guides, holiday recipe books, and Low FODMAP travel guides.
• GLP-1 Support Guides Educational handouts and guides for GLP-1 medication users including meal plans, nutrition guides, and medication management resources, ranging from free to $9.99.
• Low FODMAP AI Chef AI-powered meal planning tool that generates personalized Low FODMAP compliant recipes and cooking guidance based on dietary restrictions and preferences.
• Lab Results AI AI-powered tool for interpreting laboratory test results, providing insights and analysis of health metrics.
• Perimenopause & Menopause Quiz Evidence-based online assessment developed by Dr. Onyx MD PhD to help women identify their perimenopause stage and understand symptom patterns.
• Gift Cards Gift cards available for purchase from $10.00 USD upward, allowing recipients to shop Casa de Sante products.

Quantifiable outcome

• 3x faster protein absorption with ProHydrolase enzyme blend in whey protein formulations
• +2 more outcomes

Named customers11 records

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability4 records

Feature6 records

Partnerships

Two partnerships are on record, tiered core and minor.

• LivingPlateRxcoreChannel Partner/ Reseller/ DistributorCasa de Sante partners with LivingPlateRx to offer 30+ dietitian-prepared meal plans including Low FODMAP, SCD, AIP, Elimination Diet, Low Histamine, PCOS, Diabetes, Keto, and specialty protocols. Plans are accessible through the Casa de Sante website and provide recurring subscription revenue at $9.99/month with a free 3-day trial.
• EpicuredminorChannel Partner/ Reseller/ DistributorCasa de Sante has partnered with Epicured to provide a sustainable solution for following a low FODMAP diet through fully prepared meals and snacks by Michelin star chefs. This is offered as a plan option within the LivingPlateRx meal plan ecosystem.

Scale indicators3 records

Recent moves6 records

Expansion highlights7 records

Direct peers

• Care/of: Personalized DTC vitamin and supplement brand with quiz-based recommendations and subscription model. Comparable customer experience (assessment-led, DTC, supplements) to Casa de Sante's quiz and bundle approach.
• Physician's Choice: Digestive health supplement brand offering probiotics, digestive enzymes, and gut-focused formulations through DTC and Amazon. Closely comparable to Casa de Sante's core digestive enzyme and probiotic portfolio.
• MaryRuth's: Clean-label liquid and gummy supplement brand selling through DTC and Amazon with strong wellness positioning. Comparable channel mix and supplement category overlap with Casa de Sante.
• Ritual: Direct-to-consumer supplement brand built on clinical credibility, third-party testing, and ingredient transparency. Highly comparable to Casa de Sante's physician-formulated, clean-label positioning in the vitamins/supplements category.
• HUM Nutrition: Beauty-from-within and wellness supplement brand with quiz-driven DTC model and clinical advisory board. Comparable to Casa de Sante's assessment-led, vertically branded supplement experience.
• AG1 (Athletic Greens): Premium greens/daily nutrition powder brand with strong DTC presence, third-party testing emphasis, and content-driven marketing. Comparable in DTC supplement positioning and category-leader brand-building approach.
• Seed Health: Probiotic and gut microbiome supplement brand with proprietary delivery technology and clinical research focus. Directly comparable to Casa de Sante's core probiotics and digestive health product line.

Emerging players

• Noom: Digital health platform with strong GLP-1 support offering, nutrition coaching, and meal planning. Comparable to Casa de Sante's GLP-1 support bundle/app and dietitian-prepared meal plan offerings.

Broad incumbents

• Garden of Life: Established organic and digestive health supplement brand (Nestlé Health Science subsidiary). Operates broadly across probiotics, digestive enzymes, and protein powders — the same categories where Casa de Sante competes.
• Culturelle: Mass-market probiotic brand owned by i-Health (Chr. Hansen) with deep retail distribution. Directly competes with Casa de Sante's probiotic category but at significantly larger scale and broader portfolio.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/casa-de-sante

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Casa de Sante