What ACL Laboratories does

ACL Laboratories is a community-based clinical and anatomic pathology laboratory founded in 1997 and headquartered in the Milwaukee, Wisconsin area, now operating as a subsidiary of Advocate Health. The company provides a broad diagnostic testing menu spanning clinical chemistry, hematology, microbiology, molecular diagnostics, cytogenetics, serology, immunohistochemistry, and anatomic pathology, delivered through two affiliated pathology groups (Great Lakes Pathologists, S.C. and Midwest Diagnostic Pathology, S.C.) that together comprise over 90 board-certified pathologists examining more than 500,000 cases annually. Recent in-house additions include ADVOSEQ non-invasive prenatal aneuploidy screening (NIPS), quantitative ImmunoCAP allergy testing, and the AdvoOnc hereditary cancer testing panel.

ACL serves two primary customer segments: healthcare providers and hospitals (B2B) and individual patients (B2C). Providers place orders and receive results electronically through the EpicCare Link portal integrated with Epic EHRs, while patients access specimen collection at regional Patient Service Centers across Southeastern Wisconsin, Northern Illinois, the Chicago Metro area, and Northern Indiana, and view results through the LiveWell patient portal. Revenue is generated transactionally by billing insurance carriers, Medicare, and Medicaid for medically necessary tests; pricing is not publicly disclosed and varies by payer and coverage. Sales are supported through a content-and-bulletin-driven marketing motion (monthly test bulletins, weekly respiratory pathogen reports) rather than large-scale field sales, consistent with a referral-network business model embedded in a regional integrated health system.

Name

ACL Laboratories

Legal name

ACL LABORATORIES

Website

https://acllaboratories.com

Company type

Private

Founded year

1997

Operating status

Operating

Headcount range

11–50 employees

Short description

ACL Laboratories is a community-based clinical and anatomic pathology laboratory, part of Advocate Health, serving providers and patients across Wisconsin, Illinois, and Indiana with comprehensive diagnostic testing delivered through regional Patient Service Centers and the EpicCare Link portal.

Ownership category

akta.pro rank

Product category

Clinical Laboratory Services

NAICS

Medical Laboratories (621511)

SIC

Services-Medical Laboratories (8071)

akta.pro primary industry

Central Laboratory Services (Core Lab Operations) (HLAGAEAA)

akta.pro secondary industries

Reference & Esoteric Testing Laboratories (HLAFAMAJ), Clinical Chemistry & Immunoassay Laboratories (HLAFAMAB)

Keywords

• Clinical laboratory services
• Diagnostic testing services
• Anatomic pathology services
• Molecular diagnostics testing
• Cytogenetics and prenatal screening

Headquarters

HQ city

West Allis

HQ country

United States

HQ region

North America

Offices5 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Supply Chain

Revenue model

1. Laboratory Testing Services: ACL Laboratories provides diagnostic testing services to healthcare providers and patients. Revenue is generated through billing insurance carriers, Medicare, Medicaid, and other federally funded healthcare programs for medically necessary laboratory tests. Payment is subject to individual insurance coverage limitations.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels4 records

Core offering

ACL Laboratories is a community-based clinical laboratory that provides diagnostic testing services including clinical chemistry, hematology, microbiology, molecular diagnostics, cytogenetics, surgical pathology, and anatomic pathology. The company operates one of the nation's largest dedicated pathology networks, with more than 90 board-certified pathologists examining over 500,000 cases annually, and offers specialized panels such as ADVOSEQ non-invasive prenatal screening and AdvoOnc hereditary cancer testing.

Product overview

ACL Laboratories is a community-based clinical laboratory offering a comprehensive portfolio of diagnostic testing services. The company operates as part of Advocate Health (formerly Advocate Aurora Health) and provides laboratory services throughout Illinois, Wisconsin, and Northern Indiana. The core offering includes pathology services (anatomic and clinical) delivered by over 90 board-certified pathologists, and extensive clinical laboratory testing across disciplines including chemistry, hematology, microbiology, molecular diagnostics, cytogenetics, and immunology. Key specialized offerings include the ADVOSEQ™ Non-Invasive Prenatal Aneuploidy Screening (NIPS) and AdvoOnc™ Hereditary Cancer Testing. Services are delivered through Patient Service Centers, provider-ordered test requisitions, and electronic portals including EpicCare® Link™ for providers and LiveWell for patients.

Differentiator

Problem solved

Functional benefit

Brands

• AdvoOnc Hereditary Cancer Testing: Hereditary cancer testing service launched in June 2026

Products and services

• Laboratory Diagnostic Testing Services Comprehensive clinical laboratory diagnostic testing covering clinical chemistry, coagulation, hematology, microbiology, molecular diagnostics, immunology, endocrinology, mycology, parasitology, serology, and related disciplines; for healthcare providers and patients across the ACL service region.
• Pathology Services Full anatomic and clinical pathology services including surgical pathology, cytopathology, hematopathology, and molecular pathology, delivered by more than 90 board-certified pathologists examining over 500,000 cases annually; for healthcare providers across Wisconsin, Illinois, and Indiana.
• AdvoOnc Hereditary Cancer Testing Hereditary cancer genetic testing panel for assessing inherited cancer risk based on genetic predisposition; for healthcare providers ordering genetic risk assessment for patients.
• ADVOSEQ Non-Invasive Prenatal Aneuploidy Screening (NIPS) In-house non-invasive prenatal screening test for detecting fetal aneuploidies; for obstetricians and prenatal care providers ordering screening for pregnant patients.
• In-House Allergy Testing Quantitative ImmunoCAP fluorescent enzyme immunoassay allergy testing performed in-house on the Phadia 1000 platform; for providers ordering IgE-based allergy testing for patients.
• SwabOne Vaginitis Panel NAA-based multiplex panel for detecting vaginal pathogens including bacteria and yeast; for women's health providers diagnosing vaginitis.
• Respiratory Pathogen Panel Testing Respiratory pathogen surveillance and testing with regularly published data reports for influenza and other respiratory illnesses; for healthcare providers tracking community respiratory illness trends.

Quantifiable outcome

• Over 500,000 pathology cases examined annually

Named customers2 records

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Five partnerships are on record, tiered core.

• Advocate HealthcoreStrategic or Co-development PartnerACL Laboratories is now part of Advocate Health, one of the largest integrated healthcare systems. This partnership provides ACL with the backing and integration capabilities of a major healthcare network, enabling coordinated patient care and shared health information systems.
• Great Lakes Pathologists, S.C.coreStrategic or Co-development PartnerIndependent pathology group providing pathology services through ACL. Contact: (414) 649-7340 or (414) 328-7950. One of two pathology groups delivering pathology services with over 90 pathologists total.
• Midwest Diagnostic Pathology, S.C.coreStrategic or Co-development PartnerIndependent pathology group providing pathology services through ACL. Contact: Main Number 847-723-6268, Fax 847-723-7540, Billing 630-874-2748. President: Oliver Kim, MD. One of two pathology groups delivering pathology services.
• Advocate Aurora HealthcoreStrategic or Co-development PartnerParent health system providing patient portal integration through LiveWell platform. Medical Records Departments in Illinois and Wisconsin manage patient result requests to satisfy regulatory guidelines and HIPAA compliance.
• EpiccoreTechnology or IntegrationEpicCare Link is an Epic-compatible online portal for providers to order tests and receive laboratory results, integrated with the Epic electronic health record system.

Scale indicators4 records

Recent moves7 records

Expansion highlights5 records

Direct peers

• Quest Diagnostics: Largest US clinical laboratory network offering a comparable full-menu of routine and esoteric diagnostic testing to providers and patients across all 50 states, including overlapping service lines in clinical chemistry, molecular diagnostics, and anatomic pathology.
• Laboratory Corporation of America (Labcorp): Second-largest US clinical lab with a similarly broad menu including routine diagnostics, molecular and genetic testing, and anatomic pathology services; competes head-to-head with ACL for hospital outreach and physician office business.
• ARUP Laboratories: National reference laboratory specializing in esoteric testing; both a competitor for high-complexity send-outs and a current reference lab partner for ACL on tests like Toxoplasma IgM, making it a directly comparable specialty diagnostics operator.
• Mayo Clinic Laboratories: Reference laboratory of Mayo Clinic offering highly specialized esoteric and molecular testing to hospitals nationwide; competes with ACL for complex send-out work and represents a comparable integrated academic lab model.
• BioReference Laboratories: Full-service clinical laboratory offering routine diagnostics, molecular and genetic testing, and women's health and oncology specialty panels; directly comparable menu and customer mix to ACL.
• PathGroup: Physician-led pathology and clinical lab group providing anatomic pathology and molecular diagnostics to hospitals and physicians across the Southeast and Mid-South; a regional direct comparable to ACL's pathology-led model.

Broad incumbents

• Sonic Healthcare: Global clinical pathology operator with significant US presence (including Sonic Reference Laboratory and affiliated labs) offering routine and esoteric testing at scale; broader geographic footprint but overlapping service portfolio.

Regional players

• CompuNet Clinical Laboratories: Ohio-based community and hospital outreach laboratory with a comparable menu of clinical and anatomic pathology services and similar Patient Service Center–driven model; a regional peer operating outside ACL's Midwest footprint.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Subsidiaries2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about ACL Laboratories