What Mouse Biology Program does

The Mouse Biology Program (MBP) is a research resource program within the University of California, Davis, founded in 1997 and headquartered at 2795 Second Street, Suite 400, Davis, California. MBP develops, optimizes, and distributes genetically modified mouse model systems for biomedical research, serving academic institutions, pharmaceutical and biotechnology companies, NIH-funded research consortia, and non-profit disease foundations. The program reports 51-100 employees and operates dedicated vivaria including the M3 Barrier Facility and conventional MBP Vivarium with quarantine capabilities.

MBP's technical platform centers on advanced genetic engineering and reproductive technologies: CRISPR/Cas9 genome editing, embryonic stem (ES) cell targeting, pronuclear injection, electroporation, in vitro fertilization, embryo transfer, sperm sieve technology, embryo and sperm cryopreservation, and cryorecovery. The service portfolio spans the full mouse model lifecycle—design consultation, model creation (knockout, knockin, conditional, transgenic, genetically humanized, PDX, surgical, and rare disease models), genotyping, comprehensive phenotyping (behavioral, metabolic, morphological, physiological, imaging, pathology), cryopreservation, colony management, IVF/ICSI, and rederivation. Vertical specialty portfolios exist for oncology and immuno-oncology, neuroscience, microbiome, ADMET, and IBD research. An internally developed Project Tracking System (PTS) provides real-time online project monitoring for clients.

MBP generates revenue through professional services (custom model creation, phenotyping, cryopreservation, reproductive services), licensing of proprietary mouse models (academic and commercial tiers), one-time sales of live animals and germplasm, and hardware sales of research kits (fecal collection, sperm cryo, IVF). Pricing is quote-based and not publicly disclosed. Go-to-market is sales-led and enterprise field sales, with direct inquiry via website, phone, and email, supported by participation in NIH-funded consortia (MMRRC, MMPC, KOMP, IMPC) that channel demand. MBP has served 5,130+ clients and completed 1,030+ international projects, maintaining AAALAC International accreditation and operating as part of the University of California state system.

Name

Mouse Biology Program

Legal name

UC Davis Mouse Biology Program

Website

https://mousebiology.org

Company type

Private

Founded year

1997

Operating status

Operating

Headcount range

11–50 employees

Short description

The Mouse Biology Program at UC Davis is an academic research resource that develops genetically engineered mouse models and provides phenotyping, cryopreservation, reproductive, and pathology services to academic researchers, pharmaceutical and biotech companies, and NIH-funded consortia.

Ownership category

akta.pro rank

Product category

Preclinical Research Services

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Research and Development in the Physical, Engineering, and Life Sciences (54171)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Gene Therapy CMC/Process Development Platforms (capsid engineering, producer cell lines, plasmids, upstream/downstream) (HLAAACAN)

Keywords

• Genetically engineered mice
• Preclinical research services
• Mouse model creation
• Phenotyping services
• Cryopreservation services

Headquarters

HQ city

Davis

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Infrastructure, Technology or R&D, Operations, Supply Chain, Marketing or Sales

Revenue model

1. Mouse Model Services: Custom mouse model creation including knockout, knockin, transgenic, conditional, and genetically humanized models. Revenue generated through design consultation, molecular construct development, ES cell targeting, and model generation services.
2. Live Animal and Germplasm Sales: Sale of live mouse models and cryopreserved embryos and sperm. Pricing varies by strain type, genetic complexity, and availability. Genetically engineered models command higher prices due to modification complexity.
3. Phenotyping Services: Comprehensive phenotyping including behavioral, metabolic, morphological, and pathological assays. OMICS services including metabolomics, proteomics, and transcriptomics integrated with traditional phenotyping approaches.
4. Cryopreservation Services: Embryo and sperm cryopreservation for long-term storage and disaster recovery. Cryorecovery services for thawing and reviving cryopreserved materials.
5. Research Kits: Sale of specialized kits including fecal collection kits, sperm cryo kits, IVF kits, and related research supplies.
6. Animal Model Licensing: Licensing agreements for access to proprietary mouse models including academic research licenses for universities and non-profits, commercial licenses for biotech and pharmaceutical companies, and collaborative agreements for joint research and model co-development.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels6 records

Core offering

Mouse Biology Program (MBP) at UC Davis is a comprehensive research resource that designs, creates, characterizes, and distributes genetically engineered mouse models for biomedical research. It offers custom mouse model generation (knockout, knockin, transgenic, conditional, humanized, PDX), cryopreservation, reproductive services (IVF/ICSI), phenotyping (behavioral, metabolic, morphological), pathology, genotyping, and colony management. The program also sells live mice, cryopreserved germplasm, research kits, and licenses proprietary models to academic and commercial clients.

Product overview

The Mouse Biology Program (MBP) at UC Davis operates as a comprehensive service platform offering genetically engineered mouse models and related research services. The core portfolio includes Mouse Models (including PDX models for oncology), Mouse Kits, Murine Biospecimen Collection, and Phenotypic Data Packages as primary product offerings. These are supported by extensive laboratory and vivaria services including Genotyping, Phenotyping, Pathology, Cryopreservation, Reproductive Services (IVF/ICSI), Colony Management, and Custom Model Generation. The MBP also provides specialized domain portfolios for Oncology, Neuroscience, Microbiome, ADMET (drug development), and IBD research. The Project Tracking System serves as the central online platform for managing projects. Training programs and consultation services round out the offering, making MBP a one-stop resource for mouse model design, development, production, phenotyping, and management.

Differentiator

Problem solved

Functional benefit

Products and services

• Mouse Models Genetically engineered and mutant mouse models for biomedical research, including knockout, knockin, conditional, transgenic, and humanized models for academic institutions and pharmaceutical/biotech companies.
• PDX Mouse Models Patient-derived xenograft mouse models for cancer research, supporting tumor biology studies and therapeutic testing for oncology researchers and pharmaceutical developers.
• Custom Model Generation Solutions Tailored creation of mouse models including conditional, knockout, knockin, transgenic, and genetically humanized models designed to specific researcher specifications.
• Reproductive Services In vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), embryo transfer, rederivation, and speed congenic breeding services for colony management of laboratory mouse lines.
• Cryopreservation and Cryorecovery Services Embryo and sperm cryopreservation for long-term storage and disaster recovery, with cryorecovery services for thawing and reviving cryopreserved genetic materials.
• Phenotyping Services Comprehensive phenotyping including behavioral, metabolic, morphological, and physiological assessments for adult mice and embryos, integrated with OMICS analyses (metabolomics, proteomics, transcriptomics).
• Pathology Services Gross and histopathological examinations, necropsy, tissue collection, blood collection, and digital imaging for disease and genetic modification analysis.
• Genotyping Services Genetic analysis including coding sequence validation, genomic insertion site identification, homologous recombination confirmation, and off-target mutagenesis detection.
• Molecular Constructs Design and development of custom genetic constructs using CRISPR gene editing, BAC/Yeast Recombineering, and Gibson Assembly Cloning.
• Vivaria and Health Services Pathogen-free housing, veterinary services, quarantine procedures, ultra-clean housing facility, and gnotobiotic mouse resource center (GMRC) for specialized housing needs.
• Colony Management Services Breeding management consultation, custom breeding, and colony optimization services to maintain genetic diversity and meet experimental timelines.
• Mouse Kits Specialized research kits including Fecal Collection Kit, Sperm Cryo Kit, and In Vitro Fertilization Kit sold to researchers for laboratory applications.
• Animal Shipping Products

Quantifiable outcome

• 18,324+ services ordered historically, demonstrating extensive service delivery capacity
• +4 more outcomes

Named customers12 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Twelve partnerships are on record, tiered core and supporting.

• Mutant Mouse Resource & Research Centers (MMRRC)coreStrategic or Co-development PartnerMBP serves as a primary center in the national MMRRC network, maintaining and distributing genetically engineered mouse models. The consortium provides high-quality, well-characterized mouse strains, cryopreservation services, and related resources to researchers worldwide.
• Mouse Metabolic Phenotyping Centers (MMPC Live)coreStrategic or Co-development PartnerMBP partners with MMPC-Live offering specialized phenotyping services focused on metabolic diseases. Researchers access standardized assays, pilot funding, and expert consultation for studies in metabolism, obesity, diabetes, and related areas.
• International Mouse Phenotyping Consortium (IMPC)coreStrategic or Co-development PartnerMBP works alongside IMPC partners to systematically characterize knockout mouse strains for every gene in the mouse genome. Delivers comprehensive phenotyping data that informs genetics, disease mechanisms, and drug development studies.
• Knockout Mouse Project (KOMP)coreStrategic or Co-development PartnerMBP contributes to KOMP initiative by offering services for generating and analyzing knockout mouse models representing every gene in the mouse genome. NIH-funded program enabling researchers to access reliable genetic tools.
• UC Davis VetmedcoreStrategic or Co-development PartnerCollege of Veterinary Medicine partnership providing integrated research capabilities and shared resource access for campus-wide biomedical research initiatives.
• UC Davis Health Comprehensive Cancer CentercoreStrategic or Co-development PartnerMBP provides specialized oncology and PDX modeling services for cancer research conducted through the UC Davis Comprehensive Cancer Center, supporting tumor biology and therapeutic development studies.
• Illuminating the Druggable Genome (IDG)supportingStrategic or Co-development PartnerNIH-funded program focused on understanding the functions of understudied proteins in the human genome. MBP provides mouse model resources to support IDG research objectives.
• Kids-FirstsupportingStrategic or Co-development PartnerPediatric research data resource program. MBP supports pediatric disease research through mouse model development and characterization services.
• Undiagnosed Diseases Network (UDN)supportingStrategic or Co-development PartnerNIH program for diagnosis of mysterious medical conditions using advanced genetic and clinical approaches. MBP contributes mouse model capabilities for studying undiagnosed genetic diseases.
• Monarch InitiativesupportingStrategic or Co-development PartnerConsortium integrating biological data across species to improve disease gene discovery. MBP provides mouse model data and resources to support cross-species phenotyping analysis.
• VerndarisupportingTechnology or IntegrationBiotechnology company collaboration for research services. Verndari logo appears in MBP clients and partners section indicating ongoing research partnership.
• GemPharmaTechsupportingTechnology or IntegrationPreclinical contract research organization specializing in oncology. Logo appears in MBP clients and partners section indicating collaboration for cancer research services.

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Taconic Biosciences: Commercial supplier of genetically engineered mouse and rat models with model generation, cryopreservation, and colony management services that directly mirror MBP's core offerings.
• The Jackson Laboratory: The world's leading non-profit provider of genetically defined mouse models and preclinical research services, directly overlapping MBP's model supply, phenotyping, and cryopreservation offerings.
• European Mouse Mutant Cell Repository (EuMMCR): European repository and distribution network for mutant mouse lines, functionally analogous to MBP's MMRRC role and competing for international model distribution demand.
• genOway: Specialist in custom mouse model design and generation, including humanized and knockin/knockout models, with a similar focus on precision genetic engineering for research customers.
• Cyagen Biosciences: Custom mouse model generation provider specializing in CRISPR/Cas9, ES cell, and transgenic model creation, with overlapping design and creation services to MBP's custom model portfolio.
• GemPharmaTech: Preclinical CRO specializing in oncology mouse models and pharmacology services, an existing MBP client/partner with overlapping capabilities in cancer model generation and in vivo efficacy studies.

Broad incumbents

• Charles River Laboratories: Large commercial CRO offering research models, phenotyping, and preclinical services; competes with MBP in mouse model supply and in vivo efficacy studies as part of a much broader services portfolio.
• Inotiv: Preclinical research services and animal model provider offering in vivo pharmacology, toxicology, and model generation that competes with MBP's phenotyping and ADMET services.
• WuXi AppTec: Global CRO/CDMO with preclinical and animal model services, offering scale and geographic reach that compete with MBP for large biopharma outsourcing contracts.

Emerging players

• Crown Bioscience (JSR Life Sciences): Preclinical oncology CRO with PDX and humanized mouse model capabilities, directly comparable to MBP's oncology and immuno-oncology portfolio.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/UCDMouseBio
• Facebookfacebook.com/UCDMouseBio
• LinkedInlinkedin.com/company/mouse-biology-program-at-uc-davis

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Mouse Biology Program