PREG
PREG (Piedmont Reproductive Endocrinology Group) is the largest fertility clinic network in the Carolinas, operating six clinics and three IVF labs across South Carolina and Asheville, NC, delivering IVF, IUI, donor conception, fertility preservation, and PGT services to infertility patients, LGBTQIA+ family builders, and oncology patients.
- Company typePrivate
- Founded2003
- HeadquartersGreenville, United States
- Headcount51–100
- GTM typeB2C
- OfferingServices
What PREG does
PREG (Piedmont Reproductive Endocrinology Group) is a private reproductive medicine practice founded in 2003 by Dr. John E. Nichols in Greenville, South Carolina. It has grown into the largest fertility clinic network in the Carolinas, operating six patient-facing clinics across South Carolina (Greenville, Columbia, Summerville, Mount Pleasant, Spartanburg) and North Carolina (Asheville), supported by three on-site IVF laboratories in Greenville, Columbia, and Summerville. The practice is staffed by nine fellowship-trained reproductive endocrinologists plus a board-certified High Complexity Laboratory Director and an embryology team of PhD- and master's-level scientists with nearly 90 years of combined experience, and holds AAAASF, ASRM, SART, and CAP accreditations.
The core service offering spans the full reproductive medicine continuum: comprehensive fertility evaluation and diagnosis, intrauterine insemination (IUI), in vitro fertilization (IVF) using vitrification and extended blastocyst culture, preimplantation genetic testing (PGT-A and PGT-M), donor egg and donor sperm treatment through Fairfax EggBank and Fairfax Cryobank, third-party reproduction including gestational carriers, elective egg freezing, and oncofertility services for cancer patients. Technical capabilities include INVOcell intravaginal culture and PGT performed on trophectoderm biopsies, with vitrification as the standard cryopreservation method.
PREG operates a direct-to-consumer model — patients can self-refer without a physician referral — while simultaneously running a physician referral channel and in-house financial counseling. Revenue is generated per treatment cycle (IVF, IUI, donor egg, fertility preservation, PGT) supplemented by insurance reimbursements and employer benefit programs. PREG is in-network with all major insurance carriers and is a designated provider for Progyny, WIN, Maven, ARC Fertility, and Carrot employer-sponsored fertility benefits, and offers a layered financing stack including exclusive 0% PatientFi financing, CapexMD loans with a 10% treatment discount, Future Family loans, and Fertility Access multi-cycle refund programs that can save patients up to 40%. The practice is privately held by its founding and partner physicians with no disclosed venture or private-equity sponsorship.
PREG firmographics
Firmographics- Name
- PREG
- Legal name
- Piedmont Reproductive Endocrinology Group
- Website
- https://pregonline.com
- Company type
- Private
- Founded year
- 2003
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- PREG (Piedmont Reproductive Endocrinology Group) is the largest fertility clinic network in the Carolinas, operating six clinics and three IVF labs across South Carolina and Asheville, NC, delivering IVF, IUI, donor conception, fertility preservation, and PGT services to infertility patients, LGBTQIA+ family builders, and oncology patients.
- Ownership category
- akta.pro rank
PREG industry classification
Industry- Product category
- Reproductive Endocrinology and Fertility Treatment Services
- NAICS
- Ambulatory Health Care Services (621), Family Planning Centers (62141)
- SIC
- Services-Offices & Clinics Of Doctors Of Medicine (8011)
- akta.pro primary industry
- Fertility, Reproductive Endocrinology & IVF Centers (HLAFAJAD)
- akta.pro secondary industries
- Reproductive Endocrinology & Infertility (IVF/Fertility) (HLAKAJAC), Prenatal, Newborn & Reproductive Diagnostics (NIPT, IVF/PGT, newborn screening) (HLAAALAJ)
Keywords
Where PREG is headquartered
LocationHeadquarters
- HQ city
- Greenville
- HQ country
- United States
- HQ region
- North America
Offices6 records
Markets served
PREG business model
Business model- GTM type
- B2C
- Offering type
- Services
- Cost components
- Personnel, Operations, Infrastructure, Marketing or Sales, Technology or R&D, Supply Chain
Revenue model
- IVF Treatment Services: In vitro fertilization treatment including egg retrieval, embryo culture, embryo transfer, and related procedures. Revenue generated per treatment cycle with options for fresh and frozen embryo transfers.
- IUI Treatment Services: Intrauterine insemination treatment services, typically less expensive than IVF but less efficient. Can be coordinated with natural or medicated cycles.
- Fertility Preservation/Egg Freezing: Elective oocyte cryopreservation for women who want to preserve future fertility. One-time retrieval procedure with storage fees.
- Egg Donor Program: Compensated egg donation program where donors receive $5,000 per cycle. PREG also offers in-house donor egg services and partners with Fairfax EggBank.
- Donor Egg Treatment: IVF using donor eggs from Fairfax EggBank partnership. Donor egg programs typically range from $15,000-$25,000 plus IVF treatment costs.
- Donor Sperm Treatment: IUI or IVF with donor sperm from Fairfax Cryobank. Donor sperm specimens typically cost $900-$1,500 per vial plus treatment costs.
- Preimplantation Genetic Testing (PGT): Genetic testing of embryos for chromosomal abnormalities (PGT-A) or specific genetic conditions (PGT-M). Adds cost to IVF cycles.
- Insurance and Network Contracts: Contracts with all major insurance carriers, in-network provider for Progyny, WIN, Maven, ARC, and Carrot. Revenue received through insurance reimbursements.
- Financing Programs: Partnership with CapexMD, PatientFi, and Future Family for patient financing. Fertility Access provides bundled IVF cycle discounts and refund programs.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Pay-as-you-go | New Patient Consultation Copay |
| Unit Pricing | Pay-as-you-go | Egg Donor Compensation |
| Unit Pricing | Multi-year contract | Donor Egg Programs |
| Unit Pricing | Pay-as-you-go | Donor Sperm Specimens |
| Outcome Based/ Performance | Multi-year contract | IVF Refund Programs through Fertility Access |
| Subscription | Monthly | PatientFi 0% Financing |
| Subscription | Monthly | Insurance Coverage |
| Other | Pay-as-you-go | Samantha & Kyle Busch Bundle of Joy Fund Grant |
| Subscription | Monthly | CapexMD Financing Discount |
Go-to-market motion2 records
Distribution channels4 records
Marketing channels8 records
PREG product offering
Product offeringCore offering
PREG operates a network of six fertility clinics across the Carolinas delivering comprehensive reproductive endocrinology services, including IVF with three regional IVF labs, IUI, donor egg and donor sperm treatments via third-party reproduction partnerships, preimplantation genetic testing, fertility preservation, and oncofertility services. The practice supplements its clinical offerings with fertility evaluation, an in-house egg donor program, free second-opinion consultations, and financial counseling plus insurance/financing programs. All services are delivered by nine fellowship-trained reproductive endocrinologists and a credentialed embryology team.
Product overview
PREG (Piedmont Reproductive Endocrinology Group) is a network of six fertility clinics in the Carolinas offering a comprehensive suite of reproductive health services. The core offerings include In Vitro Fertilization (IVF) with three regional IVF laboratories, Intrauterine Insemination (IUI), donor egg and donor sperm treatments through third-party reproduction, Preimplantation Genetic Testing (PGT), fertility preservation (egg freezing), and oncofertility services for cancer patients. Supporting services include fertility evaluation and diagnosis, an egg donor program, and a free second opinion consultation service. Financial programs include IVF refund programs through Fertility Access, insurance contracting, and financing partnerships with CapexMD, PatientFi, and Future Family. All services are delivered by fellowship-trained reproductive endocrinologists at locations throughout South Carolina and Asheville, NC.
Differentiator
Problem solved
Functional benefit
Products and services
- In Vitro Fertilization (IVF) Core IVF treatment for all types of infertility, with three IVF labs in Greenville, Columbia, and Summerville; INVOcell-certified embryologists; PGT capabilities; and individualized treatment protocols featuring extended embryo culture to blastocyst stage and vitrification freezing. For patients and couples seeking the most efficient and effective fertility treatment.
- Intrauterine Insemination (IUI) A simpler, less invasive fertility treatment that places processed sperm directly into the uterus at ovulation through a small catheter. Coordinated with natural or medicated cycles and includes ultrasound monitoring. Less expensive than IVF but lower per-cycle success rates.
- Donor Egg IVF Donor egg treatment provided through partnership with Fairfax EggBank, offering access to diverse pre-screened egg donors and flexible programs including multi-egg lot options and refund programs. High success rates due to eggs from young, healthy donors.
- Donor Sperm Treatment Donor sperm utilized for IUI or IVF-based treatment through partnership with Fairfax Cryobank. Donors undergo comprehensive medical, genetic, and infectious disease screening per FDA requirements. Donor sperm specimens typically cost $900-$1,500 per vial.
- Third Party Reproduction Comprehensive third-party reproduction services including donor egg IVF, donor sperm treatment, gestational carrier utilization, and embryo donation program, supported by dedicated third-party treatment coordinators.
- Preimplantation Genetic Testing (PGT) Genetic testing of embryos including PGT-A (aneuploidy screening) and PGT-M (monogenic condition screening), performed via trophectoderm biopsy at blastocyst stage followed by vitrification while awaiting results. Adds cost to IVF cycles.
- Fertility Preservation (Egg Freezing) Planned oocyte cryopreservation (egg freezing) using vitrification to preserve fertility at a younger age for future use. Includes ovarian stimulation, egg retrieval, and vitrification. PREG also serves as an egg freezing site for a major frozen donor egg bank.
- Oncofertility Fertility preservation services for cancer patients including sperm freezing, testicular sperm extraction, IVF with egg or embryo freezing, and embryo donation. Coordinated with oncologists to minimize treatment delays.
- Fertility Evaluation and Diagnosis Comprehensive fertility evaluation including assessment of ovulatory function, male factor, tubal patency, unexplained infertility, recurrent pregnancy loss, and ovarian reserve testing to determine appropriate treatment pathways.
- Egg Donor Program Anonymous egg donation program for women ages 21-29 in good health. Donors receive $5,000 per cycle compensation, comprehensive health screening, and option to freeze their own eggs after 3 successful donation cycles; donors may participate in up to 6 donation cycles.
- IVF Laboratory Services Three comprehensive IVF laboratories in Greenville, Columbia, and Summerville, led by Dr. Jing Chen with nearly 90 years combined embryologist experience, including 3 PhDs and 5 with master's degrees. CAP accredited and fully state-of-the-art.
- Free Second Opinion Consultation Free second opinion consultation for patients who have visited other infertility practices, requiring records from prior evaluation. Provided by nine fellowship-trained reproductive endocrinologists.
Quantifiable outcome
- PGT-A normal embryos have approximately 70% chance of success per embryo transfer
- +3 more outcomes
Companies that use PREG
Customer profileNamed customers6 records
Segments6 records
Ideal customer profiles3 records
PREG technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration13 records
Feature6 records
PREG partnerships and signals
Strategic signalPartnerships
Ten partnerships are on record, tiered core and minor.
- US FertilitycoreUS Fertility is a parent organization/partnership. PREG is listed as 'A Proud Partner of US Fertility' on their website footer. US Fertility supports reproductive endocrinology practices across the US.
- Fairfax EggBankcorePREG partners with Fairfax EggBank to provide patients access to an extensive selection of carefully screened egg donors representing diverse backgrounds, along with flexible donor egg programs. Partnership allows patients efficient movement from donor selection to treatment.
- Fairfax CryobankcorePREG partners with Fairfax Cryobank to provide patients access to one of the most extensive and rigorously screened donor networks. PREG patients receive 90 days complimentary donor database access ($149 value), free shipping ($340 value), and 6 months complimentary storage ($280 value).
- ProgynycorePREG is a Progyny network provider. Progyny is a leader in fertility and family building benefits providing comprehensive fertility care access through employer benefit plans.
- WIN (WINFertility)corePREG is a WIN Treatment Program network provider offering efficient, economical access to advanced fertility treatments for patients in SC and NC with no infertility insurance coverage or exhausted benefits.
- Maven ClinicminorPREG is a Maven network provider. Maven partners with more than 2,000 employers and health plans to deliver personalized fertility care and intuitive benefit management.
- ARC FertilitycorePREG is an ARC Network provider. ARC Fertility helps employers and health plans deliver comprehensive reproductive health services with innovative approach to expedite care.
- Carrot FertilitycorePREG is a Carrot Network provider. Carrot supports members through fertility journey with personalized Carrot Plans that evolve with them, supporting health plans in expanding fertility and family-building needs.
- Livestrong FoundationcorePREG participates in Livestrong Fertility Discount Program providing at least 25% discount on egg freezing or embryo banking services for qualifying cancer patients. Partnership also includes EMD Serono providing free IVF medications to approved patients.
- TRICAREminorPREG is a TRICARE preferred provider offering discounted IVF services and working with EMD Serono for affordable fertility medications through Serono Compassionate Corps for active military and veterans.
Scale indicators8 records
Recent moves7 records
Expansion highlights5 records
PREG competitors and assessment
Company assessmentDirect peers
- CCRM (Colorado Center for Reproductive Medicine): CCRM operates a network of fertility clinics and high-complexity IVF labs with a strong focus on outcomes data and advanced lab technology. Comparable to PREG in offering comprehensive IVF, PGT, and fertility preservation with proprietary lab capabilities.
- Shady Grove Fertility (US Fertility): Shady Grove Fertility is a large multi-site fertility clinic network on the US Fertility platform, directly comparable to PREG in service mix (IVF, IUI, donor, PGT, fertility preservation) and multi-state hub-and-spoke model. It is the closest direct peer and a fellow US Fertility partner clinic.
- New Hope Fertility Center: New Hope Fertility Center is a fertility practice known for mild and natural-cycle IVF protocols alongside conventional IVF. Comparable as a multi-physician reproductive endocrinology group offering IVF, IUI, donor egg, and fertility preservation.
- Inception Fertility: Inception Fertility is a national fertility platform housing multiple clinic brands (e.g., The Fertility Partners, Aspire Fertility). It is a direct peer to PREG's US Fertility partnership structure as a multi-clinic consolidator in reproductive medicine.
- Prelude Fertility: Prelude Fertility is a national fertility services platform offering IVF, egg freezing, and genetic testing through a network of clinics. Directly comparable as a multi-site fertility provider competing for the same patient segments and payer networks as PREG.
- Boston IVF: Boston IVF is a multi-site reproductive medicine practice offering IVF, IUI, donor services, PGT, and fertility preservation across the Northeast. It shares PREG's model of fellowship-trained REIs operating multiple clinics and labs within a regional footprint.
- Reproductive Medicine Associates (RMA Network): RMA is a national network of reproductive endocrinology practices with deep research affiliations and an emphasis on evidence-based protocols. It is a direct peer in scale, multi-site delivery, and breadth of fertility services.
Emerging players
- Extend Fertility: Extend Fertility is an egg-freezing-focused clinic with a strong consumer brand and concierge-style positioning. Comparable to PREG's fertility preservation line, with overlapping target demographic but a narrower service mix.
Others
- US Fertility: US Fertility is the parent/partnership platform of which PREG is a partner clinic. It provides administrative, payer contracting, and operational infrastructure to its member practices, making it an enabling/strategic partner rather than a direct competitor.
Broad incumbents
- Mayo Clinic Fertility: Mayo Clinic offers comprehensive fertility services as part of a much larger academic health system with deep research capabilities. Relevant as a broad incumbent with overlapping REI and IVF services, competing for high-complexity cases and employer-of-choice referrals.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
PREG social profiles
Digital presencePREG compliance and trust
Trust signalCompliance4 records
PREG financial estimates
Financial estimateRevenue estimate
Valuation estimate
PREG leadership team
Management profileNumber of profiles
Profiles10 records
PREG funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
PREG M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about PREG
What does PREG do?
PREG operates a network of six fertility clinics across the Carolinas delivering comprehensive reproductive endocrinology services, including IVF with three regional IVF labs, IUI, donor egg and donor sperm treatments via third-party reproduction partnerships, preimplantation genetic testing, fertility preservation, and oncofertility services. The practice supplements its clinical offerings with fertility evaluation, an in-house egg donor program, free second-opinion consultations, and financial counseling plus insurance/financing programs. All services are delivered by nine fellowship-trained reproductive endocrinologists and a credentialed embryology team.
Is PREG a public or private company?
PREG is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was PREG founded?
PREG was founded in 2003. It employs 51 to 100 people.
Where is PREG based?
PREG is headquartered in Greenville, United States, in the North America region.
How does PREG make money?
Nine revenue lines are on record. IVF Treatment Services are the primary driver. The others are IUI Treatment Services, fertility Preservation/Egg Freezing, egg Donor Program, donor Egg Treatment, donor Sperm Treatment, preimplantation Genetic Testing (PGT), insurance and Network Contracts and financing Programs.
Who are PREG's main competitors?
Direct peers on record are CCRM (Colorado Center for Reproductive Medicine), Shady Grove Fertility (US Fertility), New Hope Fertility Center, Inception Fertility, Prelude Fertility, Boston IVF and Reproductive Medicine Associates (RMA Network). Extend Fertility is listed as an emerging player. US Fertility is listed as an others. Mayo Clinic Fertility is listed as a broad incumbent.
Does PREG have an API?
No public API is recorded for PREG.
What industry is PREG in?
PREG's product category is Reproductive Endocrinology and Fertility Treatment Services. Its primary akta.pro industry code is HLAFAJAD, Fertility, Reproductive Endocrinology & IVF Centers, with a secondary code of HLAKAJAC, Reproductive Endocrinology & Infertility (IVF/Fertility). Its NAICS code is 621 and its SIC code is 8011.