Sabeti Lab
Sabeti Lab is an academic research laboratory at the Broad Institute of MIT and Harvard that uses genomics, computational biology, and CRISPR-based diagnostics to track and combat infectious disease outbreaks, with major capacity-building programs training over 1,500 African researchers.
- Company typePrivate
- Founded2008
- HeadquartersCambridge, United States
- Headcount11–50
- GTM typeB2B
- OfferingServices
What Sabeti Lab does
Sabeti Lab is an academic research laboratory based at the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, founded in 2008 by Dr. Pardis Sabeti. The lab is dedicated to overcoming infectious diseases through the application of genomics, computational biology, and CRISPR-based diagnostic technologies. Its work is organized around four core research programs: Pathogen Genomic Surveillance and Epidemiology, Pandemic Preemption and Response, Microbial Biology and Countermeasures, and Human Genetic Variation and Disease. Core technical capabilities include real-time genomic sequencing during active outbreaks, CRISPR-Cas13-based field-deployable diagnostics, machine learning methods for rapid diagnostic design, unbiased deep sequencing for novel pathogen detection, and a 42-SNP barcode for Plasmodium vivax genotyping.
The lab does not operate as a commercial entity and does not sell products or services. It is funded primarily through research grants and institutional support, with Dr. Sabeti holding an Howard Hughes Medical Institute (HHMI) Investigator position that represents an investment of $153 million over five years across 26 investigators. Major platforms include the Sentinel pandemic preemption system (designated an Audacious Project by TED in 2020), the African Center of Excellence in Genomics of Infectious Disease (ACEGID, launched 2013) which has trained over 1,500 researchers and healthcare professionals from 38 African countries, the Mirador biomedical data visualization tool, and the Operation Outbreak STEM educational platform. The lab also serves as the research origin point for two commercial biotech ventures co-founded by Dr. Sabeti: SHERLOCK Biosciences (CRISPR-based diagnostics) and Delve Bio (infectious disease diagnostics). Its principal "customer" relationships are with public health agencies (Massachusetts Department of Public Health, West African health systems), academic partner institutions (Redeemer's University, Tulane, Scripps, Harvard, MGH), and grant funders (HHMI, NIH).
Sabeti Lab firmographics
Firmographics- Name
- Sabeti Lab
- Legal name
- Sabeti Lab
- Website
- https://sabetilab.org
- Company type
- Private
- Founded year
- 2008
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Sabeti Lab is an academic research laboratory at the Broad Institute of MIT and Harvard that uses genomics, computational biology, and CRISPR-based diagnostics to track and combat infectious disease outbreaks, with major capacity-building programs training over 1,500 African researchers.
- Ownership category
- akta.pro rank
Sabeti Lab industry classification
Industry- Product category
- Infectious Disease Genomics Research
- NAICS
- Medical Laboratories (621511), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
- SIC
- Services-Medical Laboratories (8071)
- akta.pro primary industry
- Laboratory-Based Surveillance & Genomic Epidemiology (WGS/NGS) (HLAJABAC)
- akta.pro secondary industries
- Microbiology & Infectious Disease Diagnostics (Culture/ID/AST) (HLAHAAAC), Microbiology & Infectious Disease Diagnostics (culture, rapid antigen, syndromic panels) (HLAAALAC)
Keywords
Where Sabeti Lab is headquartered
LocationHeadquarters
- HQ city
- Cambridge
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Sabeti Lab business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Operations, Infrastructure, Marketing or Sales
Revenue model
- Research Funding and Grants: Academic research laboratory funded through grants from institutions including Howard Hughes Medical Institute (HHMI), NIH, and other research funding bodies. Dr. Sabeti is an HHMI investigator receiving flexible support. The lab also accepts donations through the Broad Institute for supporting the mission.
- Co-founded Companies: Dr. Sabeti is a co-founder of SHERLOCK Biosciences and Delve Bio, which may generate licensing revenue or equity value, though specific revenue arrangements are not detailed.
Go-to-market motion1 record
Distribution channels2 records
Marketing channels5 records
Sabeti Lab product offering
Product offeringCore offering
Sabeti Lab is an academic research laboratory that develops and applies genomic and computational technologies to study viral pathogens (Ebola, Lassa, Zika, Mumps, SARS-CoV-2) and to enable pandemic preemption. The lab combines advanced sequencing, CRISPR-Cas diagnostics, and machine learning for rapid diagnostic design, and runs large-scale training and capacity-building programs (ACEGID, Sentinel, Operation Outbreak) to support public health response in West Africa and globally.
Product overview
Sabeti Lab is a research laboratory focused on overcoming infectious diseases through genomics and computation. The lab operates four interconnected research programs: Pathogen Genomic Surveillance & Epidemiology for tracking viral outbreaks; Pandemic Preemption and Response for developing CRISPR-based diagnostics and machine learning tools; Microbial Biology and Countermeasures for understanding viral mutations and therapeutic development; and Human Genetic Variation and Disease for identifying disease-associated genomic variants. Key platforms include Sentinel (pandemic preemption system), Mirador (biomedical data visualization tool), ACEGID (training programs for African scientists), and Operation Outbreak (educational simulation platform).
Differentiator
Problem solved
Functional benefit
Brands
- ACEGID (African Center of Excellence in Genomics of Infectious Disease): A partnership established in 2013 between institutions in Nigeria, Sierra Leone, Senegal, and the U.S. to provide training and capacity building in genomics for the next generation of African genomic scientists. ACEGID has trained over 1,500 researchers and healthcare professionals from 38 African countries.
- Sentinel
- Operation Outbreak
Products and services
- Sentinel Pandemic preemption system that uses applied genomic epidemiology, training, and mentorship to expand West and Central Africa's capacity to rapidly detect, respond to, and develop countermeasures for endemic and epidemic diseases. Established Sentinel sites in hospitals across Nigeria and Sierra Leone with groundwork in Senegal and Liberia.
- Mirador Visual exploration software tool for complex biomedical data sets, using Mutual Information-based correlation measures to find patterns and build predictive models. Developed with Fathom Information Design as part of the Sentinel team.
- ACEGID Training Programs African Centre of Excellence in Genomics of Infectious Disease (ACEGID) providing comprehensive training and capacity building for African researchers and healthcare professionals in viral genomic research and surveillance. Has trained over 1,500 researchers and healthcare professionals from 38 African countries.
- Operation Outbreak STEM-focused educational platform grounded in outbreak prevention and preparedness curriculum with Bluetooth-based simulation, designed for inclusivity across educational and socioeconomic backgrounds.
- Pathogen Genomic Surveillance & Epidemiology Research Program Research program that builds and applies advanced genomic and computational technologies to study viral pathogens including Ebola, Lassa, Zika, Mumps, and SARS-CoV-2, with collaborative research programs in Nigeria, Sierra Leone, and Senegal.
Quantifiable outcome
- First to use real-time DNA sequencing in the midst of a deadly pandemic during the 2014 Ebola outbreak in West Africa
- +2 more outcomes
Companies that use Sabeti Lab
Customer profileNamed customers5 records
Segments3 records
Ideal customer profiles3 records
Sabeti Lab technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability8 records
Feature7 records
Sabeti Lab partnerships and signals
Strategic signalPartnerships
20 partnerships are on record, tiered core, major and minor.
- African Center for Genomics of Infectious Disease (ACEGID)corePartnership with Redeemer's University in Nigeria, launched ACEGID in 2013. A partnership between institutions in Nigeria, Sierra Leone, Senegal, and the U.S. designed to provide training and capacity building in Africa for the next generation of African genomic scientists. Has trained over 1300 researchers and healthcare professionals from 38 African countries.
- Broad Institute of MIT and HarvardcoreSabeti Lab's home institution. Dr. Sabeti is a core institute member of the Broad Institute and leader in the Infectious Disease and Microbiome Program. The team works alongside members of the Broad's scientific programs and platforms.
- Harvard UniversitycoreDr. Sabeti is a tenured faculty member in the Department of Organismic and Evolutionary Biology at Harvard University. She teaches Life Sciences 1b with around 400 undergraduates each year.
- Harvard T.H. Chan School of Public HealthcoreDr. Sabeti is tenured faculty in the Department of Immunology and Infectious Disease. Long-standing collaborations with the Dyann Wirth Lab and others including Bill Hanage and Yonatan Grad.
- Massachusetts General HospitalcoreDr. Sabeti is faculty at MGH. The lab works closely with Jacob Lemieux's lab (now faculty in ID Division), Eric Rosenberg, Sarah Turbett, John Branda, and the MGH Micro Lab. Also collaborates with Shibani Mukerji, Regina Larocque, and Doug Kwon.
- Redeemer's UniversitycoreWorking with Christian Happi and his team at Redeemer's University. Together launched ACEGID in 2013 as a partnership between Nigerian, Sierra Leonean, Senegalese, and U.S. institutions.
- Viral Hemorrhagic Fever ConsortiummajorCollaboration studying viral hemorrhagic fevers, with Lassa fever as the primary focus. Partners include Bob Garry at Tulane, Christian Happi at ACEGID, Kristian Andersen at Scripps, Bob Tesh at UTMB Galveston, and Annie Rimoine at UCLA.
- Tulane UniversitymajorCollaboration with Bob Garry at Tulane University through the Viral Hemorrhagic Fever Consortium studying Lassa fever and other viral hemorrhagic fevers.
- Scripps Research InstitutemajorLong-standing collaboration with Kristian Andersen (former postdoc, now faculty at Scripps) since 2009, studying viral hemorrhagic fevers.
- DimagimajorOver 5 years of collaboration developing apps to collect laboratory and patient data in West Africa for front-line workers. Part of the Sentinel team. CommCare mobile platform used by 600,000 frontline workers tracking 400+ million people globally.
- Fathom Information DesignmajorAward-winning studio in Boston developing tools to understand microbial genomic and epidemiological data. Part of the Sentinel team and supports Operation Outbreak with dashboard building.
- Massachusetts Consortium on Pathogen ReadinessmajorCollaboration with Harvard Medical School, UMassMed, and Boston University to prepare for future pandemics. Working with Jeremy Luban at UMassMed, Mike Springer at HMS, John Connor and Anna Honko at BU on genomic epidemiology.
- Operation OutbreakmajorCo-founded by Dr. Sabeti alongside Todd Brown at Sarasota Military Academy and Andres Colubri at UMassMed. STEM-focused educational platform with outbreak prevention curriculum and Bluetooth-based simulation for inclusivity across educational backgrounds.
- Massachusetts Department of Public HealthmajorClose collaboration to analyze and inform responses to outbreaks across Massachusetts. Work during Zika virus epidemic (2015-2016), mumps outbreaks (2016-2017), and SARS-CoV-2 outbreak. Conducting routine surveillance, outbreak investigations, and pandemic response.
- Colorado Mesa UniversityminorCollaboration with John Marshall and Amy Bronson at CMU developing methods for surveillance on college campuses during COVID response.
- COVIDCheck ColoradominorCollaboration during COVID pandemic for COVID response programs alongside Colorado Mesa University.
- Irrua Specialist Teaching Hospital, Nigeriacore140 physicians and ~16,000 annual patients in rural Nigeria where Lassa is endemic with yearly outbreaks. Collaboration on Lassa fever research, part of ACEGID network.
- Kenema Government Hospital, Sierra LeonecoreLocated in area with highest Lassa Fever prevalence globally. Lassa Fever and Ebola research and biomedical infrastructure expansion at this site.
- SHERLOCK BiosciencesmajorDr. Sabeti is a co-founder of SHERLOCK Biosciences, which develops CRISPR-based diagnostic technologies.
- Delve BiomajorDr. Sabeti is a co-founder of Delve Bio, a company in the diagnostics/infectious disease space.
Scale indicators6 records
Sabeti Lab competitors and assessment
Company assessmentOthers
- Broad Institute of MIT and Harvard: Sabeti Lab's home institution and key partner. The Broad's Infectious Disease and Microbiome Program shares overlapping researchers, infrastructure, and genomic sequencing capabilities with Sabeti Lab.
- Scripps Research Institute: Long-standing collaborator with Kristian Andersen (former Sabeti Lab postdoc) studying viral hemorrhagic fevers. Comparable academic infectious disease genomics research mission and technology stack.
Broad incumbents
- Cepheid (Danaher): Cepheid is a leading molecular diagnostics company with GeneXpert systems deployed globally for infectious disease testing, including in West Africa. Comparable diagnostic focus but a commercial incumbent with much broader product portfolio.
- Ginkgo Bioworks: Ginkgo Bioworks acquired Concentric by Ginkgo for biosecurity and pathogen surveillance, comparable to Sabeti Lab's genomic surveillance work. Operates at much larger scale and broader scope across synthetic biology.
Direct peers
- Day Zero Diagnostics: Day Zero Diagnostics uses whole-genome sequencing and machine learning to identify bacterial pathogens and predict antibiotic resistance. Overlaps with Sabeti Lab's genomic surveillance and ML-driven diagnostic design work.
- SHERLOCK Biosciences: Co-founded by Dr. Pardis Sabeti, SHERLOCK Biosciences develops CRISPR-based molecular diagnostics directly stemming from Sabeti Lab's CRISPR-Cas13 research. Same target market (infectious disease diagnostics) and same underlying technology platform.
- Karius: Karius applies next-generation sequencing to detect pathogens in blood for infectious disease diagnosis. Comparable in using genomic/computational methods to identify infectious agents, targeting similar clinical and hospital customers.
- Delve Bio: Co-founded by Dr. Sabeti, Delve Bio is a metagenomic infectious disease diagnostics company that leverages the lab's unbiased deep sequencing capabilities. Directly comparable in infectious disease diagnostic focus and origin from Sabeti Lab research.
Emerging players
- Metabiota: Metabiota built a pandemic risk analytics platform using epidemiological and outbreak data, highly parallel to Sabeti Lab's Sentinel program goals of pandemic preemption via data analytics.
- Phylagen: Phylagen uses environmental DNA sequencing and genomic surveillance to monitor biological threats. Comparable in applying genomic epidemiology to early pathogen detection, though with a different anchor market (built environment / supply chain).
Market position
Strengths5 records
Weaknesses5 records
Key risks6 records
Key highlights7 records
Customer concentration
Sabeti Lab social profiles
Digital presenceSabeti Lab financial estimates
Financial estimateRevenue estimate
Valuation estimate
Sabeti Lab leadership team
Management profileNumber of profiles
Profiles1 record
Sabeti Lab funding detail
Funding detailFunding overview
Funding rounds
Investors
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Sabeti Lab M&A and investment
M&A and investmentM&A
Investments
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Frequently asked questions about Sabeti Lab
What does Sabeti Lab do?
Sabeti Lab is an academic research laboratory that develops and applies genomic and computational technologies to study viral pathogens (Ebola, Lassa, Zika, Mumps, SARS-CoV-2) and to enable pandemic preemption. The lab combines advanced sequencing, CRISPR-Cas diagnostics, and machine learning for rapid diagnostic design, and runs large-scale training and capacity-building programs (ACEGID, Sentinel, Operation Outbreak) to support public health response in West Africa and globally.
Is Sabeti Lab a public or private company?
Sabeti Lab is a private company. It is classified as nonprofit foundation owned and is currently operating.
When was Sabeti Lab founded?
Sabeti Lab was founded in 2008. It employs 11 to 50 people.
Where is Sabeti Lab based?
Sabeti Lab is headquartered in Cambridge, United States, in the North America region.
How does Sabeti Lab make money?
Two revenue lines are on record. Research Funding and Grants are the primary driver. The others are co-founded Companies.
Who are Sabeti Lab's main competitors?
Others on record are Broad Institute of MIT and Harvard and Scripps Research Institute. Broad incumbents are Cepheid (Danaher) and Ginkgo Bioworks. Direct peers are Day Zero Diagnostics, SHERLOCK Biosciences, Karius and Delve Bio. Emerging players are Metabiota and Phylagen.
Does Sabeti Lab have an API?
No public API is recorded for Sabeti Lab.
What industry is Sabeti Lab in?
Sabeti Lab's product category is Infectious Disease Genomics Research. Its primary akta.pro industry code is HLAJABAC, Laboratory-Based Surveillance & Genomic Epidemiology (WGS/NGS), with a secondary code of HLAHAAAC, Microbiology & Infectious Disease Diagnostics (Culture/ID/AST). Its NAICS code is 621511 and its SIC code is 8071.