Apexus

What Apexus does

Apexus LLC is the HRSA-designated Prime Vendor for the federal 340B Drug Pricing Program, operating under an exclusive government contract awarded through a competitive bid process effective December 31, 2019, and headquartered in Irving, Texas. The company supports 13,300+ covered entities — including safety-net hospitals, disproportionate share hospitals, Federally Qualified Health Centers, and rural health clinics — plus 70+ pharmaceutical manufacturers, providing access to discounted medications, manufacturer contracting, refund services, and compliance support. Apexus also delivers the industry's 340B ACE (Apexus Certified Expert) professional certification through the Advanced 340B Operations Certificate Program, an award-winning 40-hour curriculum and the only recognized industry credential for 340B expertise.

The technology stack centers on the Apexus Education Portal (a learning management system), the Apexus Answers national 340B call center aligned with HRSA, an iOS/Android mobile application, and the secure 340B Prime Vendor Program website. Education is delivered through 340B University (100+ in-person and virtual sessions as of December 2024), an OnDemand content library, webinars, and recertification programs. The Apexus Fellowship in Health Care Solutions and Access and a PGY2 Health-System Pharmacy Administration Rotation extend the platform into pharmacy residency training. Refund resolution — the Covered Entity Refund Service (CRS) and Manufacturer Refund Service (MRS) — handles nearly 390,000 refunds to date, with over 99% dollar acceptance.

Revenue flows through multiple streams: administrative fees under the HRSA Prime Vendor contract (paid by participating manufacturers), certificate program enrollment fees ($750 for covered entities, $1,250 for non-covered entities, $200 for biennial recertification), and professional services fees for refund processing. Group and association discounts (AIMM, AEH, APhA, ASHP, NACHC, AAPT member discounts of $100) support volume enrollment. Apexus is a private LLC affiliated with Vizient, the healthcare performance improvement company, and serves as the dominant — and effectively sole — prime vendor intermediary in the 340B ecosystem.

Name

Apexus

Legal name

Apexus, LLC

Website

https://apexus.com

Company type

Private

Founded year

2019

Operating status

Operating

Headcount range

51–100 employees

Short description

Apexus LLC is the HRSA-designated Prime Vendor for the federal 340B Drug Pricing Program, serving 13,300+ covered entities and 70+ manufacturers with contracting, education, and refund services. It also operates the industry's only recognized 340B ACE professional certification program.

Ownership category

akta.pro rank

Product category

340B Drug Pricing Program Administration

NAICS

Drugs and Druggists' Sundries Merchant Wholesalers (42421)

SIC

Wholesale-Drugs, Proprietaries & Druggists' Sundries (5122)

akta.pro primary industry

340B Program Administration & Contract Pharmacy Services (HLAFALAL)

akta.pro secondary industry

Government Pricing & Compliance (Medicare/Medicaid/340B/AMP/Best Price) (HLAIAKAE)

Keywords

• 340B Drug Pricing Program
• Prime Vendor Services
• Pharmacy Compliance Services
• Healthcare Education Programs
• Pharmaceutical Refund Services

Headquarters

HQ city

Irving

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. HRSA 340B Prime Vendor Program Contract: Apexus is the HRSA-designated Prime Vendor for the 340B Drug Pricing Program. The Prime Vendor Program is available at no cost to eligible entities and is funded through manufacturer contracting and administrative fees.
2. Advanced 340B Operations Certificate Program: Professional training certification program with enrollment fees: $750 for covered entities, $1,250 for non-covered entities, and $200 for recertification. Includes 33.25 hours of continuing education credit.
3. Covered Entity Refund Service (CRS): Facilitates return of ineligible 340B discounts to manufacturers, providing streamlined refund resolution for compliance issues.
4. Manufacturer Refund Service (MRS): Helps pharmaceutical manufacturers compliantly resolve 340B overcharges to covered entities through a 4-step refund process including data review, HRSA-aligned communications, refund execution, and auditable reporting.

Pricing tiers

Go-to-market motion1 record

Distribution channels5 records

Marketing channels6 records

Core offering

Apexus serves as the HRSA-designated Prime Vendor for the federal 340B Drug Pricing Program, providing access to discounted medications, education, technical assistance, and contracting services to 13,300+ covered entities serving vulnerable populations. Beyond the Prime Vendor mandate, Apexus sells an Advanced 340B Operations Certificate Program with the 340B ACE designation, and operates Covered Entity and Manufacturer Refund Services to resolve 340B compliance issues.

Product overview

Apexus is the HRSA-designated Prime Vendor for the 340B Drug Pricing Program, offering a comprehensive suite of solutions including the 340B Prime Vendor Program as its core offering, the Advanced 340B Operations Certificate Program for professional certification (with ACE designation), the Covered Entity Refund Service for compliance issue resolution, the Apexus Education Portal for online learning, 340B University for stakeholder education, Apexus Answers national call center, and the Apexus Mobile App for on-the-go access. The company also provides specialized training programs including a PGY2 Health-System Pharmacy Administration Rotation and a one-year Fellowship in Health Care Solutions and Access.

Differentiator

Problem solved

Functional benefit

Products and services

• 340B Prime Vendor Program HRSA-designated Prime Vendor Program that provides access to discounted medications, education, technical assistance, and contracting services to 340B covered entities serving vulnerable populations. Available at no cost to eligible entities and funded through manufacturer contracting and administrative fees.
• Apexus Advanced 340B Operations Certificate Program Professional certification program that validates 340B expertise with 33.25 hours of CE credit; graduates earn the trademarked 340B ACE (Apexus Certified Expert) designation.
• Covered Entity Refund Service (CRS)

Quantifiable outcome

• Serve over 13,300 covered entities with medications, education, and compliance support
• +2 more outcomes

Named customers3 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Nine partnerships are on record, tiered core and minor.

• 340B Compliance PartnerscoreStrategic or Co-development Partner · 1 January 2025Pharmacist-owned consulting firm providing 340B compliance support to covered entities. Selected as 2025 Consultant Contributor to the Advanced 340B Operations Certificate Program, contributing educational content and expertise to support advanced 340B education and certification.
• SpendMendcoreStrategic or Co-development Partner · 1 January 2025Comprehensive 340B Program and pharmacy solutions firm. Selected as 2025 Consultant Contributor (also 2024, 2022, 2020, 2019) providing content development, webinars, and tools including 'Carry the One' and 'Cracking the Code' courses for the certificate program.
• FQHC 340B ComplianceminorStrategic or Co-development Partner · 1 January 2024Specialized 340B compliance firm for Federally Qualified Health Centers. Previous Consultant Contributor in 2024.
• Ponaman Healthcare ConsultingminorStrategic or Co-development Partner · 1 January 2023Healthcare consulting firm providing 340B expertise. Previous Consultant Contributor in 2023.
• Blue & Co. Consulting ServicesminorStrategic or Co-development Partner · 1 January 2022Consulting firm providing healthcare and pharmacy services. Previous Consultant Contributor in 2022.
• Rx | X ConsultingminorStrategic or Co-development Partner · 1 January 2021Pharmacy consulting firm. Previous Consultant Contributor in 2021.
• The Alinea GroupminorStrategic or Co-development Partner · 1 January 2020Healthcare consulting group. Previous Consultant Contributor in 2020 and 2019.
• VisanteminorStrategic or Co-development Partner · 1 January 2019Pharmacy consulting firm specializing in 340B and supply chain solutions. Previous Consultant Contributor.
• ASHP FoundationminorGTM or Marketing Partner · 1 January 2019Apexus is a corporate partner with the ASHP Foundation, supporting pharmacy professional development and education initiatives.

Scale indicators6 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• CaptureRx: 340B solutions provider offering split-billing software and contract pharmacy services to covered entities. CaptureRx directly competes with Apexus's covered-entity-facing compliance and operational support offerings in the 340B ecosystem.
• SunRx: 340B program management and contract pharmacy platform serving covered entities. SunRx overlaps with Apexus's covered-entity-facing compliance and contract pharmacy enablement offerings.
• Verity Solutions: 340B software and compliance solutions provider for covered entities. Verity Solutions competes in the same 340B compliance and split-billing space as Apexus, serving hospitals and health systems with software tools to manage 340B program operations.
• Macro Helix: Provider of 340B split-billing software (340B Architect) and pharmacy supply chain analytics. Macro Helix competes directly with Apexus for 340B software and compliance engagements among covered entities.
• 340B Compliance Partners: Pharmacist-owned 340B consulting firm providing compliance support to covered entities. 340B Compliance Partners is a 2025 Apexus Consultant Contributor and competes directly in the 340B consulting and audit services market.
• Sentry Data Systems: 340B SaaS and managed services provider (now part of Cantex Continuing Care Network / private ownership). Sentry offers 340B split-billing, contract pharmacy, and compliance software that overlaps directly with Apexus's covered-entity support services.

Emerging players

• SpendMend: Comprehensive 340B program and pharmacy solutions firm offering consulting, auditing, and operational support. SpendMend is a recurring Apexus Consultant Contributor and a direct competitor in the 340B consulting and audit segment.
• Visante: Pharmacy and 340B consulting firm specializing in supply chain optimization and 340B program design. Visante is a former Apexus Consultant Contributor that competes for 340B consulting engagements with covered entities and health systems.

Broad incumbents

• 340B Health: National advocacy association representing hospitals and health systems participating in the 340B program. 340B Health is a broader industry incumbent that influences the regulatory and policy environment in which Apexus operates, rather than competing head-to-head on services.
• MedImpact Healthcare Systems: Independent PBM offering 340B program management and contract pharmacy services as part of a broader pharmacy benefit portfolio. MedImpact overlaps with Apexus on 340B services but operates a much wider PBM business that is not 340B-specialized.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/apexusllc

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Apexus