NUVOLA S.R.L.

What NUVOLA S.R.L. does

NUVOLA S.R.L. (operating as Nuvola World Srl) is an Italian orthodontic device company that designs, manufactures, and distributes clear aligner systems and proprietary treatment protocols to licensed dental professionals. Its core technology is the Evolution™ hybrid co-polyester aligner material, paired with the Nuvola OP System, which combines aligner biomechanics with functional myofunctional therapy using Nuvola Pro™ aligners (featuring lingual pins and sectorial expansion zones) and the Freedom™ myofunctional device. Nuvola Junior extends the platform to pediatric and growing-patient orthodontics using the Intercept device. The product portfolio is augmented by a digital ecosystem including the NuvolaWeb clinician platform for case management, Nuvola Analytics (3D cephalometric scanning via partner BIOMAX), Dental Check (patient monitoring app), Magic Smile (a patented augmented reality smile preview app), and Neve home whitening.

The company operates a B2B go-to-market, selling exclusively through registered clinicians (orthodontists and dentists) via quote-based, per-case pricing structured around treatment levels A, B, C, and PLUS, each with defined refinement phases (1-4) and multi-year expiration windows. Distribution is digital-first through the NuvolaWeb platform, with separate portals for Americas (nuvolaclient.com) and EU/Worldwide (nuvolaclient.eu), supplemented by an aggressive clinician education program comprising in-person training courses, the annual Verona congress (co-organized with BIOMAX), and multilingual webinars. The company is privately held, founder-controlled (Dr. Alessandro Carrafiello, inventor of the OP System), with headquarters in Vicenza, Italy and a new training-focused facility in Rome opened in 2025. Active markets include Italy, the US, Spain, Hungary, and the UK.

Name

NUVOLA S.R.L.

Legal name

Nuvola World Srl

Website

https://nuvolaworld.com

Company type

Private

Operating status

Operating

Headcount range

11–50 employees

Short description

NUVOLA S.R.L. (Nuvola World Srl) is an Italian orthodontic device company that designs, manufactures, and sells clear aligners and functional orthodontic protocols (Nuvola OP System, Nuvola Junior) to licensed dentists and orthodontists via its NuvolaWeb digital platform and clinician training programs.

Ownership category

akta.pro rank

Product category

Orthodontic Aligners

NAICS

Dental Laboratories (339116), Dental Equipment and Supplies Manufacturing (339114), Resin and Synthetic Rubber Manufacturing (32521)

SIC

Dental Equipment & Supplies (3843), Wholesale-Medical, Dental & Hospital Equipment & Supplies (5047), Plastic Materials, Synth Resins & Nonvulcan Elastomers (2821)

akta.pro primary industry

Clear Aligner Orthodontics (HLABABAD)

akta.pro secondary industries

Orthodontic Appliances & Aligners Fabrication (HLABAJAD), Cosmetic & Esthetic Dentistry (Veneers/Whitening/Bonding) (HLABAAAC)

Keywords

• Clear orthodontic aligners
• Myofunctional therapy devices
• Aligner manufacturing systems
• Orthodontic digital platform
• Dental treatment protocols

Headquarters

HQ city

Vicenza

HQ country

Italy

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Personnel, Marketing or Sales, Technology or R&D, Infrastructure

Revenue model

1. Clear Aligner Products: Nuvola sells clear invisible aligner systems to dental professionals. Treatment plans are submitted through NuvolaWeb platform with levels A, B, C, and PLUS determining the number of aligners and refinement phases included. Aligner phases are shipped (typically 24 upper and 24 lower per phase).
2. Nuvola Pro Aligners with Freedom Device: Combined OP System protocol using Nuvola Pro aligners with the Freedom myofunctional device for functional orthodontic treatment.
3. Neve Home Whitening: Home whitening product that accompanies Nuvola aligners. Single-dose vials of whitening gel applied inside custom-made Nuvola aligners.
4. Training and Education Programs: Nuvola provides training courses, congresses, and webinars for dental professionals to learn the Nuvola system and OP protocols.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

Nuvola World Srl designs, manufactures, and distributes clear invisible orthodontic aligners and proprietary treatment protocols (Nuvola OP System, Nuvola Junior) made from its proprietary Evolution™ hybrid co-polyester material, sold exclusively to dental professionals through the NuvolaWeb clinician platform. The company supplements its manufactured aligners with the Freedom™ myofunctional device, Nuvola Analytics 3D cephalometry, Dental Check patient app, Magic Smile AR preview, and Neve home whitening as an integrated orthodontic ecosystem.

Product overview

Nuvola is a Made-in-Italy orthodontic system comprising clear invisible aligners and associated treatment protocols. The core portfolio includes: Nuvola Clear Invisible Aligners (standard aligner therapy using proprietary Evolution™ material), the Nuvola OP System (combining Nuvola Pro™ aligners with Freedom™ myofunctional device for complex functional cases), and Nuvola Junior (pediatric aligner system for growing patients). Supporting products include Nuvola Analytics (3D cephalometry app), Dental Check (patient communication app), Magic Smile (AR smile simulation), Neve (whitening gel), and the NuvolaWeb clinician platform for case management.

Differentiator

Problem solved

Functional benefit

Products and services

• Nuvola Clear Invisible Aligners Metal-free, transparent custom-made orthodontic aligners manufactured in Italy from Nuvola's proprietary Evolution™ hybrid co-polyester material, prescribed and ordered by registered orthodontists and dentists via the NuvolaWeb platform for adult patients with mild to severe crowding, diastemas, mild and moderate malocclusions, pre-prosthetic treatments, and post-orthodontic relapses. Shipped in phases of 24 upper and 24 lower aligners.
• Nuvola OP System Innovative orthodontic protocol combining classic aligner biomechanics with functional orthodontic therapy, using Nuvola Pro™ aligners (with lingual pins, push areas, and sectorial expansion zones) together with the Freedom™ myofunctional device. Indicated for complex cases including Class II, pseudo Class III, deep bite, unilateral and bilateral crossbite, strong transverse discrepancies, and open bite from tongue thrusting. Sold exclusively to dental professionals via NuvolaWeb.
• Nuvola Junior Pediatric orthodontic system for growing patients with deciduous or mixed dentition, combining Nuvola aligners with the Intercept functional device (typically worn less than 90 minutes per day) to correct transverse, vertical, and sagittal problems, malocclusions with dysfunction, open bite, and atypical swallowing.
• Freedom™ Myofunctional Device Myofunctional intraoral device that reprograms muscle memory, leads to balanced contraction of the pterygoid muscles, and creates a centrifugal tensive effect directed posteriorly and externally. Used together with Nuvola Pro aligners as part of the OP System protocol for functional orthodontic therapy.
• Nuvola Analytics (by BIOMAX) Mobile application (developed by BIOMAX) that performs 3D scans of the patient's face and carries out guided surface cephalometric assessments, evaluating the predictability of orthodontic treatments and highlighting critical issues such as volumetric symmetry at zygomatic bones and mandibular gonia angles.
• Dental Check Patient-facing mobile application that facilitates communication between patient and dentist during clear-aligner treatment: patients see treatment progress, receive notifications when to change aligners, and can send photos to the dentist for remote checking.
• Magic Smile (Patented) Patented augmented-reality mobile application that applies a preview of orthodontic treatment results onto the patient's face, allowing patients to see a virtual mirror of their new smile designed using Nuvola aligners.
• Neve Home Whitening Home whitening system designed to accompany Nuvola aligners, consisting of single-dose vials of whitening gel applied inside the patient's custom-made Nuvola aligners over a two-week period following an initial practice application.
• NuvolaWeb Clinician Platform Digital platform for registered clinicians to register, submit patient cases (scans/impressions), review and approve NuvolaView 3D treatment simulations, order aligner phases, request refinements, track shipments, manage patients, and communicate with Nuvola support. Separate portals for American customers (nuvolaclient.com) and EU/Worldwide customers (nuvolaclient.eu).

Quantifiable outcome

• Refinement phases included in treatment cost based on level (Level A: 1, Level B: 2, Level C: 3, Level PLUS: 4)
• +3 more outcomes

Named customers8 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability4 records

Feature8 records

Partnerships

One partnership is on record.

• BIOMAXcoreTechnology or IntegrationBIOMAX developed the Nuvola Analytics app, a proprietary application for performing 3D scans and cephalometric assessments. This partnership provides Nuvola's digital ecosystem with advanced analytics capabilities for treatment planning and evaluation.

Scale indicators2 records

Recent moves4 records

Expansion highlights4 records

Direct peers

• Straumann Group (ClearCorrect): ClearCorrect is Straumann's doctor-channel clear aligner brand, headquartered in the US and sold in Europe. Directly comparable to Nuvola as a competing aligner system with a digital workflow and clinician training program.
• Align Technology: Maker of Invisalign, the global clear aligner market leader. Directly comparable to Nuvola as a doctor-channel clear aligner manufacturer with proprietary materials, 3D treatment planning software (ClinCheck), and a global training/sales footprint. Sets the competitive benchmark Nuvola must outperform on complex cases.
• Angelalign Technology: One of the largest clear aligner manufacturers globally, with strong presence in Asia and expanding into Europe. Comparable to Nuvola as a specialty aligner brand targeting orthodontists with proprietary materials and digital workflow.
• Envista Holdings (Ormco / Spark Aligners): Through Ormco and Spark Aligners, Envista is a direct competitor in the doctor-channel clear aligner market. Compares to Nuvola on aligner product, case management software, and clinician training, with substantially greater global commercial scale.

Emerging players

• SmileDirectClub: Pioneer of direct-to-consumer and hybrid clear aligners. Comparable to Nuvola on clear aligner manufacturing but operates a fundamentally different (direct-to-consumer) go-to-market; illustrates the consumer-facing adjacent to Nuvola's doctor-only model.
• uLab Systems: Maker of uSmile aligners and in-office treatment planning software for orthodontists. Comparable to Nuvola as a smaller specialty aligner competitor focusing on clinician workflow and digital tools.
• OrthoFX: US-based clear aligner company founded by former Align Technology executives, targeting orthodontists with a polymer-based aligner. Comparable to Nuvola as a specialty aligner company challenging Invisalign with proprietary materials and clinician-only distribution.

Broad incumbents

• Dentsply Sirona (SureSmile): Dentsply Sirona is a global dental equipment and consumables giant whose SureSmile aligner platform competes with Nuvola in the clear aligner category. Broader portfolio (chairs, imaging, instruments) gives it scale advantages but clear aligners are one of many lines.
• Solventum (formerly 3M Oral Care / Clarity Aligners): Solventum continues the 3M Clarity aligner line and provides a direct competitive alternative to Nuvola clear aligners in the doctor channel, backed by an enormous incumbent dental supplies business.

Others

• Henry Schein: World's largest dental distributor and a key channel for orthodontic products. Relevant to Nuvola as a potential distribution partner and as a benchmark for the economics of selling dental consumables and equipment to clinicians.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

• Facebookfacebook.com/NuvolaWorldAligners
• LinkedInlinkedin.com/company/nuvola-world

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about NUVOLA S.R.L.