Msbase Foundation Limited

What Msbase Foundation Limited does

MSBase Foundation Ltd is an Australian non-profit founded in 2004 and headquartered in Melbourne that operates MSBase, the largest international online registry for neurologists studying multiple sclerosis and other neuro-immunological diseases. The platform enables 186 contributing centers across 43 countries to capture standardized longitudinal patient data through iMed Web, an in-house data collection and visualization tool, and to participate in investigator-initiated sub-studies, comparative effectiveness research, and peer-reviewed publications (100+ to date). The foundation also operates MGBase, launched in 2024 as the first global observational registry for Myasthenia Gravis, and the MSBase Imaging Repository which integrates icobrain AI-powered brain volumetry for member use. Principal Investigators retain data ownership and can opt out of research requests.

The platform is hosted on Microsoft Azure with ISO/IEC 27001 certification, multilayered encryption, and geo-blocking controls. MSBase does not charge membership fees; its revenue is sourced from pharmaceutical supporter partnerships (Merck, Roche, Novartis, UCB) and collaborative registry agreements with OFSEP, the Danish, Italian, and Swedish MS registries within the Big MS Data Network. Distribution is community-led, driven by scientific publications, conference presentations at events such as ECTRIMS, KOL endorsements, and member testimonials, with self-serve enrollment through registry.msbase.org. The organization operates a Scientific Leadership Group and sub-committees that govern research priorities, while a Board of Directors provides corporate oversight.

Name

Msbase Foundation Limited

Legal name

MSBase Foundation Ltd

Website

https://msbase.org

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

1–10 employees

Ownership category

akta.pro rank

Product category

Clinical Research Registry Platform

NAICS

Web Search Portals, Libraries, Archives, and Other Information Services (5192), Web Search Portals and All Other Information Services (51929)

SIC

Services-Health Services (8000)

akta.pro primary industry

Data Access, Sharing & Marketplace Platforms (incl. TEFCA/QHIN enablement) (HLACAIAL)

Keywords

• Multiple sclerosis registry
• Clinical research platform
• Real-world evidence
• Patient data registry
• Neuroimmunological disease research

Headquarters

HQ city

Melbourne

HQ country

Australia

HQ region

Oceania

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Infrastructure, Operations, Marketing or Sales

Revenue model

1. Pharmaceutical Industry Partnerships: The organization receives support from pharmaceutical companies including Merck, Roche, Novartis, and UCB. These appear to be funding partnerships supporting the registry operations and research activities rather than commercial product relationships.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels4 records

Core offering

MSBase Foundation operates a global collaborative research registry platform that enables neurologists to contribute longitudinal patient data on multiple sclerosis and other neuro-immunological diseases. The core iMed Web tool provides structured data collection and real-time patient tracking for clinicians, while the platform supports investigator-initiated sub-studies, statistical analyses, and free access to AI-powered imaging metrics through the MSBase Imaging Repository.

Product overview

Msbase Foundation Limited operates a unified research platform centered on the MSBase Registry, an international online registry for multiple sclerosis research. The core offering includes the MSBase Registry for observational data collection and the iMed Web data collection and visualization tool. The platform extends through MGBase (Myasthenia Gravis Registry), the MSBase Imaging Repository with AI-powered metrics, and the MS Severity Rank Calculator. These products work together to enable collaborative epidemiological research, with over 20 years of longitudinal data collection supporting real-world evidence studies across neuro-immunological diseases.

Differentiator

Problem solved

Functional benefit

Brands

• MGBase: The first global observational registry for patients diagnosed with Myasthenia Gravis
• iMed Web

Products and services

• MSBase Registry An international online observational registry for neurologists and MS researchers that enables longitudinal patient data contribution, sub-study creation, dataset access requests, and collaborative epidemiological and outcomes research across 186 centers in 43 countries.
• iMed Web A user-friendly data collection and visualization tool designed for clinicians treating MS patients during routine consultations, enabling structured patient tracking, real-time monitoring, and comparison of local cohorts against the global registry.
• MGBase Registry The first global observational registry for patients diagnosed with Myasthenia Gravis, applying MSBase's collaborative research framework to a new neuro-immunological disease area.
• MS Severity Rank Calculator An online tool that calculates MS severity rankings for individual patients based on registry data, supporting clinicians in assessing disease progression relative to the broader MSBase population.

Quantifiable outcome

• 100+ publications in high impact journals produced by MSBase investigators
• +2 more outcomes

Named customers6 records

Segments1 record

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Six partnerships are on record, tiered collaborating registry, infrastructure and technology integration.

• OFSEP (Observatoire Français de la Sclérose en Plaques)collaborating registryStrategic or Co-development PartnerFrench MS registry collaborating with MSBase on multi-registry observational cohort studies, particularly for ocrelizumab comparative effectiveness research combining data from MSBase, OFSEP, and Danish MS Registry.
• Danish MS Registrycollaborating registryStrategic or Co-development PartnerDanish national MS registry partnered with MSBase for multi-registry studies comparing disease-modifying therapies across international datasets.
• Italian MS Registercollaborating registryStrategic or Co-development PartnerItalian national MS registry collaborating within the Big MS Data Network framework alongside MSBase, OFSEP, and Swedish MS Registry for disability progression research.
• Swedish MS Registrycollaborating registryStrategic or Co-development PartnerSwedish national MS registry collaborating within the Big MS Data Network for primary progressive MS research and other collaborative studies.
• Microsoft AzureinfrastructureTechnology or IntegrationCloud infrastructure provider hosting the MSBase registry data with multilayered security, SQL encryption, and regulatory compliance certifications including ISO 27001, FedRAMP/FISMA, SOC and PCI DSS.
• icobraintechnology integrationTechnology or IntegrationAI-powered brain volumetry technology integrated with MSBase for automated MRI analysis, offered complimentary to registry members for clinical practice.

Scale indicators6 records

Recent moves6 records

Expansion highlights5 records

Emerging players

• PatientsLikeMe: PatientsLikeMe is a patient-led outcomes platform collecting structured patient-reported data across conditions including MS. It is comparable to MSBase as a longitudinal patient data asset used for real-world research and pharma insights, though with less clinically curated data.
• icobrain (icometrix): icometrix develops AI-powered MRI quantification tools (icobrain) used in MS and other neurological conditions. It is comparable to MSBase as it operates in the same MS imaging research space, and is integrated into MSBase's imaging repository offering.

Broad incumbents

• IQVIA Real World Evidence: IQVIA is the largest global real-world evidence provider, aggregating clinical and claims data to support pharma research across indications. It is comparable to MSBase as a real-world data vendor to pharma, though operating at vastly greater scale across all disease areas rather than a focused MS/neuro-immunology registry.
• Flatiron Health: Flatiron Health aggregates de-identified oncology EHR data for real-world evidence generation and serves major pharma sponsors. It is comparable to MSBase as a real-world clinical data platform monetized via pharma partnerships, though focused on oncology rather than neurology.
• TriNetX: TriNetX operates a global federated health research network providing real-world evidence to pharma and academic researchers. It is comparable to MSBase as a clinical data network used for real-world studies, but operates across many disease areas rather than specializing in MS/neuro-immunology.

Regional players

• UK MS Register: The UK MS Register is a national MS registry collecting both patient-reported and clinical data from UK centers. It is comparable to MSBase in providing longitudinal MS real-world evidence, though geographically focused on the UK.

Direct peers

• CLIMB Registry (Brigham and Women's Hospital): CLIMB (Comprehensive Longitudinal Investigation of MS at Brigham) is a deeply phenotyped longitudinal MS cohort with imaging and clinical data. It is comparable to MSBase in offering long-term MS outcomes data, though with a smaller, single-institution footprint rather than a multi-center global registry.
• OFSEP (Observatoire Français de la Sclérose en Plaques): OFSEP is the French national MS registry that collaborates with MSBase in the Big MS Data Network. It is comparable as a large, multi-center MS registry generating real-world evidence used by French and international MS researchers, though it is anchored on a national data sovereignty model.
• NARCOMS Registry: NARCOMS is a North American patient registry for multiple sclerosis that collects longitudinal, patient-reported outcomes. It is directly comparable to MSBase as both are large, multi-center MS data registries supporting observational research and pharma-sponsored real-world evidence studies.
• Danish MS Registry: The Danish MS Registry is a national MS registry that collaborates with MSBase via the Big MS Data Network for multi-registry studies. It is comparable as a structured longitudinal MS dataset used for comparative effectiveness research, though anchored on Denmark's national health system.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/msbase

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

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M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Msbase Foundation Limited