Name

Lettercase

Legal name

Lettercase National Center for Prenatal and Postnatal Resources

Website

https://lettercase.org

Company type

Private

Operating status

Operating

Headcount range

1–10 employees

Ownership category

akta.pro rank

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Others

Revenue model

1. Donations and Charitable Contributions: As a nonprofit organization, Lettercase is funded through donations. Funds go toward providing free materials to medical providers and expectant parents, presenting at national conferences, and adding multiple translations.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels5 records

Core offering

Lettercase is a nonprofit organization that serves as the nation's clearinghouse and comprehensive training center for sharing accurate, balanced, and up-to-date information about genetic conditions. It provides free educational resources (in 15 languages) and training programs for medical professionals and patient advocacy organizations, plus direct support materials for expectant and new parents receiving a prenatal or postnatal diagnosis, primarily of Down syndrome and related genetic conditions.

Product overview

Lettercase is a non-profit organization (The National Center for Prenatal and Postnatal Resources) that serves as the nation's clearinghouse and comprehensive training center for sharing accurate, balanced, and up-to-date information about genetic conditions. The organization operates as part of the Genetic Support Foundation and provides a unified portfolio of free resources and training programs. The core offerings include: Lettercase Resources (free educational materials available in 15 languages), Training for Medical Professionals (continuing education on diagnosis communication), Training for Advocacy Organizations (outreach strategy programs), and the Down Syndrome Transition Handbook. Related programs include Down Syndrome Pregnancy for expectant parent support. The organization does not charge for its resources and focuses on ensuring expectant parents and providers have support at the moment of diagnosis.

Differentiator

Problem solved

Functional benefit

Products and services

• Lettercase Resources Free, balanced, and medically-reviewed educational resources about genetic conditions for expectant parents and medical professionals, available in 15 languages and reviewed by representatives of national medical, genetics, and advocacy organizations.
• Training for Medical Professionals Free online training modules and technical assistance for medical professionals about best practices for supporting new and expectant parents learning about a genetic diagnosis, with continuing medical education (CME) and continuing education (CEU) credits available.
• Training for Advocacy Organizations Training programs for patient advocacy groups on medical outreach strategies and supporting new and expectant parents, including monthly Medical Outreach Meetings for local Down syndrome organizations.
• Down Syndrome Transition Handbook A comprehensive guide to prepare and support families and providers through transitioning to adult care for individuals with Down syndrome, covering medical transitions, IEP goals, post-secondary programs, legal matters, and funding resources.
• Down Syndrome Pregnancy A program supporting new and expectant parents of children with Down syndrome who are preparing for the birth of a baby with Down syndrome or welcoming a new baby, offering more detailed information for families.
• Lunch and Learn Presentation A 30-minute template presentation for medical providers to deliver information about Down syndrome, designed for advocacy organizations to use during outreach to healthcare providers.
• Medical Outreach Program Program providing resources and training to help advocacy organizations reach and educate medical providers about genetic conditions and best practices for diagnosis communication.
• State Laws Resources Information about Down Syndrome/Genetic Conditions Information Acts passed in each state and corresponding department of health resources, with almost all states recommending Lettercase resources as part of their state fact sheets.

Quantifiable outcome

• Resources recommended by almost all states as part of state fact sheets under Down Syndrome Information Acts
• +2 more outcomes

Named customers4 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Seven partnerships are on record, tiered core and major.

• Genetic Support FoundationcoreStrategic or Co-development Partner · 1 October 2024Lettercase became part of the Genetic Support Foundation (GSF) in October 2024, strengthening its mission with organizational support. GSF provides direct genetic counseling services and shares Lettercase's values of compassion, equity, and empowering families through informed decision-making. Dr. Stephanie Meredith was named Development Director at GSF.
• Alliance for Disability Justice and Ethics in Reproductive GeneticscoreStrategic or Co-development Partner · 1 January 2024A collaborative alliance focused on disability rights and ethics in reproductive genetics, with regular meetings including sessions in January 2026 and April 2026. Led by Dr. Stephanie Meredith and Katie Stoll, MS, CGC.
• Partners: Genetic Conditions Consensus GroupmajorStrategic or Co-development PartnerCoalition of organizations working together on genetic conditions advocacy and education initiatives.
• Partners: Down Syndrome CollaborativemajorStrategic or Co-development PartnerCollaborative group of Down syndrome organizations working together on shared goals including medical outreach and advocacy.
• National Society of Genetic Counselors (NSGC)majorGTM or Marketing PartnerProfessional organization whose search tool helps families find genetic counselors. Genetic counselors are key contacts for Lettercase's medical outreach programs and Lunch and Learn presentations.
• Down Syndrome PregnancymajorStrategic or Co-development PartnerRelated program of the National Center that supports expectant parents preparing for the birth of a baby with Down syndrome, offering more detailed information for families.
• National Organization for Rare Disorders (NORD)majorStrategic or Co-development PartnerComprehensive hub for rare disease information that Lettercase refers families to for additional condition-specific resources and support organizations.

Scale indicators3 records

Recent moves7 records

Expansion highlights6 records

Broad incumbents

• March of Dimes: Large maternal and infant health nonprofit producing prenatal education materials and outcome research; comparable on expectant-parent education and policy advocacy, but with substantially broader maternal health focus.
• National Down Syndrome Society: Largest U.S. Down syndrome advocacy organization; overlaps on expectant-parent resources, medical outreach, and state-level policy advocacy, but operates a much broader national programmatic portfolio.
• National Organization for Rare Disorders (NORD): Comprehensive hub for rare-disease information that Lettercase actively refers families to; comparable on patient-education clearinghouse function but across thousands of rare conditions rather than a focused prenatal niche.
• National Down Syndrome Congress: National membership organization serving the Down syndrome community across the lifespan; comparable on medical outreach and family education but with a broader advocacy and convention-driven scope.
• Genetic Alliance: Federation of advocacy organizations supporting individuals with genetic conditions; comparable on coalition-building and resource aggregation, but with a network-of-networks model versus Lettercase's direct publishing approach.

Emerging players

• National Society of Genetic Counselors (NSGC): Professional association whose search tool helps families find genetic counselors — a key medical-outreach contact for Lettercase; adjacent rather than directly competitive, but overlaps on educational content for the genetic counseling community.
• Expecting Health: Nonprofit providing genetic education and resources for expectant parents; closely comparable on prenatal screening education, though more oriented toward emerging genomic technologies and newborn screening.

Regional players

• Healthy Birth Day: Nonprofit known for the Count the Kicks stillbirth-prevention campaign; shares the expectant-parent education and provider-outreach model but focuses on stillbirth prevention rather than genetic-condition diagnosis communication.

Direct peers

• Down Syndrome Pregnancy: A related program of the same National Center that supports new and expectant parents preparing for the birth of a baby with Down syndrome; overlaps directly with Lettercase's expectant-parent content and audience.
• Genetic Support Foundation: Parent 501c3 nonprofit providing genetic counseling services since 2012; operates in the same prenatal/postnatal genetics space and shares mission, leadership, and infrastructure with Lettercase since the October 2024 integration.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/lettercase

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Lettercase