What Synapticure does

Synapticure (SynaptiCure, Inc.) is a Chicago-headquartered, Delaware-incorporated virtual neurology clinic focused exclusively on neurodegenerative diseases — Alzheimer's disease and other dementias, Parkinson's disease and movement disorders, ALS and motor neuron diseases, and related conditions. Founded in 2022 and operated in partnership with CareND Provider Group, P.A., the company delivers 100% of its clinical services via telehealth across all 50 U.S. states, pairing specialist video consultations with dedicated care coordinators, 24/7 caregiver support, mental health services, proactive at-home genetic testing with pre- and post-test counseling, and clinical trial matching. The platform is HIPAA-compliant, SOC 2 Type 2 certified, and carries Joint Commission Ambulatory Health Care Accreditation awarded in 2024.

The underlying technology is a secure telehealth platform enabling two-way interactive video visits, asynchronous patient communications, and care-navigation workflows, with no physical clinic footprint. Synapticure integrates these modules into a single patient journey beginning at intake via the my.synapticure.com portal or phone line (855-255-5917) and continuing through specialist visits, genetic counseling, trial enrollment, and ongoing caregiver coordination. Reported clinical-operations metrics include a patient Net Promoter Score of 95 versus a healthcare industry average of 38, a one-day average care-coordinator response time, and sub-14-day time-to-physician.

The revenue model is insurance reimbursement for telehealth visits (Medicare, Medicaid, UnitedHealthcare, BlueCross BlueShield and other commercial payers, with typical patient cost of $0–$40 per visit) layered with the CMS GUIDE Model dementia program, which delivers care coordination and up to 80 hours of respite care annually at no cost to eligible Traditional Medicare beneficiaries. Synapticure has raised approximately $71 million cumulatively through 2024 from GV, B Capital, CVS Health Ventures, Optum Ventures, CommonSpirit Health, RA Capital Management, Rock Health Capital, Y Combinator, and others, and employs 51–100 people.

Name

Synapticure

Legal name

SynaptiCure, Inc.

Website

https://synapticure.com

Company type

Private

Founded year

2022

Operating status

Operating

Headcount range

51–100 employees

Short description

Synapticure is a Chicago-based virtual neurology clinic providing telehealth care across all 50 U.S. states for patients with neurodegenerative diseases including Alzheimer's, Parkinson's, and ALS, combining specialist consultations with care coordination, genetic testing, and clinical trial matching.

Ownership category

akta.pro rank

Product category

Telehealth Neurology Services

NAICS

Home Health Care Services (62161), Home Health Care Services (6216), Services for the Elderly and Persons with Disabilities (624120)

SIC

Services-Health Services (8000), Services-Home Health Care Services (8082), Services-Nursing & Personal Care Facilities (8050)

akta.pro primary industry

Memory Care Care Management & Navigation (Dementia Care Coordination) (HLADACAJ)

akta.pro secondary industries

Dementia Care Coordination & Care Planning (HSABAEAJ), Post-Diagnosis Transition & Hospital-to-Home Dementia Support (HSABAEAL), In-Home Dementia Care Services (Specialized Personal Care) (HLADACAI)

Keywords

• Telehealth neurology care
• Neurodegenerative disease care
• Dementia care coordination
• Virtual movement disorder care
• ALS specialty care

Headquarters

HQ city

Chicago

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Telehealth Services - Insurance Reimbursement: Virtual neurology consultations billed to Medicare, Medicaid, and major commercial insurers. On average, most in-network visits cost $0-40 for patients. GUIDE Model services available at no additional cost to eligible Traditional Medicare beneficiaries.
2. Series A Funding: Institutional venture capital investment led by B Capital for Series A round of $25 million to expand virtual care services across all 50 states

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels4 records

Core offering

Synapticure operates a fully virtual neurology practice delivering expert care for patients with neurodegenerative diseases including Alzheimer's, Parkinson's, ALS, and related conditions across all 50 U.S. states. Services are delivered via telehealth and bundled into a single care experience: video visits with specialized neurologists, dedicated care coordination and 24/7 support, at-home genetic testing and counseling, clinical trial matching, mental health services, and the CMS GUIDE Model dementia care program.

Product overview

Synapticure operates as a virtual-first telehealth clinic offering a unified care platform for patients with neurodegenerative diseases including Alzheimer's, Parkinson's, ALS, and related conditions. The core platform provides video-based neurology consultations, supplemented by integrated modules including the CMS GUIDE Model for dementia care coordination (offered at no cost to Medicare beneficiaries), genetic testing and counseling, clinical trial matching, mental health services, and dedicated care navigation. All services are delivered via telehealth across all 50 U.S. states, with insurance coverage including Medicare and Medicaid.

Differentiator

Problem solved

Functional benefit

Products and services

• Synapticure Virtual Care Platform A fully virtual neurology practice that delivers video-based consultations with expert neurologists to patients with Alzheimer's, Parkinson's, ALS, and other neurodegenerative diseases across all 50 U.S. states, including dedicated care coordination and 24/7 caregiver support.
• CMS GUIDE Model Program A dementia care coordination program under the CMS Guiding an Improved Dementia Experience (GUIDE) Model providing no-cost comprehensive care navigation, caregiver support, and up to 80 hours per year of respite care to eligible Traditional Medicare beneficiaries with a confirmed dementia diagnosis.
• Genetic Testing and Counseling Proactive at-home genetic testing with pre- and post-test genetic counseling for patients with neurodegenerative diseases, identifying mutations such as SOD1 that can directly alter treatment plans, with costs covered or minimized whenever possible.
• Clinical Trial Matching Service that proactively identifies and matches Synapticure patients with neurodegenerative diseases to relevant clinical trials nationwide, with neurologists and care coordinators reviewing medical history and discussing risk-benefit profiles.
• Mental Health Care Services Comprehensive mental health support bundled into Synapticure's care model, including psychiatric services, individual and group therapy, and dedicated caregiver mental health support for individuals and families affected by neurological conditions.
• Care Coordination and Navigation Personalized care coordinator assignment and ongoing care navigation that helps patients and families manage every facet of the healthcare system, including insurance navigation, prior authorization, appointment scheduling, transportation, meal delivery, and local provider coordination.

Quantifiable outcome

• 95 Patient NPS vs healthcare industry average of 38
• +4 more outcomes

Named customers5 records

Segments4 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Seven partnerships are on record, tiered major and minor.

• Pearl HealthmajorStrategic or Co-development PartnerPartner listed in CMS GUIDE Model collaborators section. Partnership focused on providing breakthrough support for dementia care through value-based care enablement.
• LunaminorStrategic or Co-development PartnerPartner listed in CMS GUIDE Model collaborators section. Part of Synapticure's network of local organizations for arranging respite care services.
• Hilarity for CharityminorStrategic or Co-development PartnerPartner listed in CMS GUIDE Model collaborators section. Alzheimer's and dementia-focused charitable organization supporting caregiver resources.
• BAYADA Home Health CareminorStrategic or Co-development PartnerPartner listed in CMS GUIDE Model collaborators section. Home health care provider for arranging in-home respite care services.
• Senior HelpersminorStrategic or Co-development PartnerPartner listed in CMS GUIDE Model collaborators section. Senior care services provider for respite care coordination.
• Massachusetts General HospitalmajorStrategic or Co-development PartnerMajor clinic collaborator at company launch. Synapticure works with major clinics like Mass General Hospital to expand access to personalized ALS care through telemedicine.
• UCSF (University of California, San Francisco)majorStrategic or Co-development PartnerMajor clinic collaborator at company launch. Synapticure collaborates with UCSF to provide specialized ALS and neurodegenerative disease care via telemedicine.

Scale indicators8 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Tembo Health: Tembo Health is a telehealth practice focused on dementia and memory care for older adults, delivering specialist neurology and psychiatric support virtually. It is directly comparable to Synapticure in target patient population, care model, and neurodegenerative specialty focus.
• Isaac Health: Isaac Health provides virtual, in-home memory and dementia care, including specialist consultations, care navigation, and cognitive assessments. It is a direct competitor in the dementia-focused telehealth category with overlapping clinical services and patient segments.
• Neura Health: Neura Health is a virtual neurology clinic serving patients with headache, migraine, and other neurological conditions via telehealth. While broader than Synapticure's neurodegenerative focus, it competes in the same virtual neurology delivery model and patient demographic.
• Roon: Roon is a direct-to-consumer telehealth platform offering expert medical information and virtual consultations from neurologists and other specialists. It is comparable to Synapticure in its D2C telehealth neurology positioning and consumer-first patient experience.

Emerging players

• Linus Health: Linus Health provides digital cognitive assessment and brain health platform used by clinicians to detect and monitor cognitive impairment and dementia. It is adjacent rather than directly competing, but overlaps with Synapticure's dementia diagnostic and care-coordination workflow.
• Remo Health: Remo Health offers virtual dementia care and support for patients and caregivers, including care navigation and clinical services. It overlaps with Synapticure's GUIDE-style dementia care coordination but operates at a smaller scale and narrower service mix.

Broad incumbents

• Teladoc Health: Teladoc Health is a large, publicly traded virtual care platform offering general medical, behavioral, and specialty telehealth services. It is a broad incumbent that increasingly competes with Synapticure in chronic and specialty care, though it lacks Synapticure's neurodegenerative depth.
• Amwell: Amwell is a major telehealth infrastructure and virtual care platform serving health systems, insurers, and consumers. As a broad incumbent with enterprise health-system relationships, it overlaps with Synapticure's provider referral channel and could expand into specialty neurology.
• Included Health: Included Health (formerly Doctor On Demand + Grand Rounds) is a virtual care and care navigation company offering primary, behavioral, and specialty care plus expert medical opinions. It competes with Synapticure for employer and payer partnerships in specialty care delivery.
• One Medical / Amazon One Medical: One Medical, now part of Amazon, is a membership-based primary care platform with growing chronic and specialty care services. It is a broad incumbent expanding into longitudinal specialty care, overlapping with Synapticure's chronic neurodegenerative patient population and payer relationships.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/synapticure

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds5 records

Investors14 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Synapticure