Ayble Health
Ayble Health is a digital health platform delivering AI-personalized nutrition and behavioral health programs for patients with gastrointestinal conditions such as IBS and IBD. It sells tiered consumer subscriptions reimbursed by insurance and licenses its platform to health systems, employers, and health plans including Cleveland Clinic, Mayo Clinic, and Priority Health.
- Company typePrivate
- Founded2020
- HeadquartersBoston, United States
- Headcount11–50
- GTM typeB2B and B2C
- OfferingSoftware
What Ayble Health does
Ayble Health is a digital health platform that delivers personalized nutrition and behavioral health care for people with gastrointestinal conditions such as Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD). The platform combines an AI-assisted recommendation engine — built on what the company describes as the largest GI data ecosystem, enabling personalization from 200 quadrillion possible combinations — with a Mind-Gut behavioral program using cognitive behavior therapy, gut-directed hypnosis, and acceptance and commitment therapy. A Food Discovery Engine with item scanner and 2.3 million recipes supports trigger-food identification, while a physician-facing remote monitoring module integrates the program into clinical workflows for gastroenterologists and health systems.
The core product is offered as a tiered subscription ($39.99 to $49.99 per month for 4 to 12-month programs) and is reimbursed by health insurance, with most members paying $0 out of pocket and copays typically under $60 per month. Ayble operates a hybrid go-to-market model: direct-to-consumer self-serve onboarding through a mobile app combined with enterprise B2B sales to employers, health plans, and benefits brokers. Flagship commercial relationships include Cleveland Clinic, Mayo Clinic, Priority Health (1.3M members), and Apex Benefits, alongside a United Healthcare Marketplace listing. The company is venture-backed with approximately $4.6 million raised from M13, Upfront Ventures, Founder Collective, and Inflect Health, and is based in Boston.
Founded by Sam Jactel in 2020 based on his personal experience with Ulcerative Colitis, Ayble has assembled a clinical advisory board spanning Cleveland Clinic, Harvard Medical School / Brigham & Women's Hospital, Massachusetts General Hospital, Northwestern, and the IMAGINE network, and has published outcomes research in Gastroenterology, Inflammatory Bowel Diseases, and Clinical & Translational Gastroenterology showing 80%+ symptom improvement. The company is the first and only gastroenterology firm independently validated by the Validation Institute.
Ayble Health firmographics
Firmographics- Name
- Ayble Health
- Legal name
- Ayble Health, Inc.
- Website
- https://ayblehealth.com
- Company type
- Private
- Founded year
- 2020
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Ayble Health is a digital health platform delivering AI-personalized nutrition and behavioral health programs for patients with gastrointestinal conditions such as IBS and IBD. It sells tiered consumer subscriptions reimbursed by insurance and licenses its platform to health systems, employers, and health plans including Cleveland Clinic, Mayo Clinic, and Priority Health.
- Ownership category
- akta.pro rank
Ayble Health industry classification
Industry- Product category
- Digital Gastrointestinal Care Platform
- NAICS
- Software Publishers (5132), Social Assistance (624)
- SIC
- Services-Health Services (8000), Services-Prepackaged Software (7372)
- akta.pro primary industry
- Gastroenterology Telemedicine Platforms (HLALAGAE)
- akta.pro secondary industries
- Medical Nutrition Therapy (Registered Dietitian) (HSADAFAE), Patient Education, Content & Personalized Journey Orchestration (HLACAEAE), Healthcare & Wellness Personalization (HDAAAGAI)
Keywords
Where Ayble Health is headquartered
LocationHeadquarters
- HQ city
- Boston
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Ayble Health business model
Business model- GTM type
- B2B and B2C
- Offering type
- Software
- Cost components
- Technology or R&D, Personnel, Marketing or Sales, Operations, Infrastructure
Revenue model
- Subscription - Consumer Direct: Direct-to-consumer subscription model with tiered membership options ranging from Essentials ($49.99/mo) to comprehensive bundles ($39.99/mo with annual commitment). Most members pay $0 through health insurance coverage.
- Enterprise B2B - Employer Health Plans: B2B enterprise licensing agreements with employers and health plans to provide digestive health benefits as part of employee benefits packages. Organizations bear the burden of unmanaged gut health symptoms driving demand for employer-sponsored coverage.
- Health Insurance Reimbursement: Ayble Health submits claims to health insurers for eligible and covered Medical Services. Most Ayble members pay $0 for their care through health insurance, with copays typically less than $60/month when applicable.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Monthly | Essentials - Core GI nutrition program |
| Subscription | Monthly | Essentials + Exploration - Extended trigger identification |
| Subscription | Monthly | Essentials + Exploration + Deep Dive - Comprehensive 12-month program |
Go-to-market motion3 records
Distribution channels6 records
Marketing channels6 records
Ayble Health product offering
Product offeringCore offering
Ayble Health operates a clinically-backed digital health platform that delivers personalized nutrition planning, GI psychology programs (CBT, gut-directed hypnosis, ACT), and access to licensed GI dietitians and health coaches for individuals with gastrointestinal conditions such as IBS and IBD. The platform combines AI-powered personalization from a proprietary GI data ecosystem with a food discovery engine, barcode item scanner, and 2.3 million recipes, and is offered directly to consumers via subscription as well as through employer health benefits, health plan coverage, and health system clinical integrations.
Product overview
Ayble Health is a unified digital health platform offering personalized GI nutrition and mental health care. The core Ayble Health Platform serves as the central hub, supplemented by the Mind-Gut Program for psychological interventions and the Food Discovery Engine for dietary management. The platform is offered through tiered subscription programs (Essentials, Essentials + Exploration, and Essentials + Exploration + Deep Dive) ranging from 4 to 12 months of access. For clinical partners and health systems, Ayble offers a physician-facing remote monitoring platform. For employers and health plans, enterprise benefits packages are available. The Learning Hub provides supplementary educational content, and all offerings are covered by insurance with most members paying $0 through their health insurance.
Differentiator
Problem solved
Functional benefit
Products and services
- Ayble Health Platform A personalized GI nutrition and mental health care platform that combines behavior science and clinical protocols to help patients manage digestive conditions through AI-powered symptom tracking, trigger food identification, and virtual care team access. Targeted at individuals with IBS, IBD, and other GI conditions.
- Physician-Facing Remote Monitoring Platform A clinical partner platform that integrates at the point of care, allowing clinicians to remotely recommend and track patients' progress through GI behavioral programs and creating a comprehensive at-home and in-clinic experience. Targeted at health systems, gastroenterologists, and clinical providers.
- Enterprise Health Benefits An employer and health plan offering providing science-backed digital gut health care to organizations, addressing GI conditions that impact 70M Americans and generate $140B in direct medical spend annually. Targeted at employers, health insurers, and benefits brokers/consultants.
Quantifiable outcome
- 81%+ of users report improved digestive symptoms (vs 24-70% for other tools)
- +4 more outcomes
Companies that use Ayble Health
Customer profileNamed customers4 records
Segments3 records
Ideal customer profiles3 records
Ayble Health technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration1 record
AI capability6 records
Feature5 records
Ayble Health partnerships and signals
Strategic signalPartnerships
Eleven partnerships are on record, tiered flagship, core and supporting.
- Cleveland ClinicflagshipCleveland Clinic is collaborating with Ayble Health to provide virtual behavioral health and nutrition counseling to GI patients. The model, co-developed by both organizations, is described as the first of its kind in the GI space. It aims to keep patients engaged between visits while addressing a projected shortage of 1,600+ GI specialists by 2025. Both organizations are working to integrate their systems and expand insurance coverage to increase patient accessibility. Cleveland Clinic's Dr. Stephen Lupe, Director of Behavioral Medicine, serves as a clinical advisor to Ayble.
- Mayo ClinicflagshipMayo Clinic and Ayble Health collaborated to make GI care less complicated and to treat high-acuity patients in person. The partnership integrates Ayble's digital care platform with Mayo Clinic's clinical expertise for comprehensive GI care delivery.
- Priority HealthcorePriority Health, a nonprofit health plan serving over 1.3 million members, partnered with Ayble Health for digestive health as part of a shift from treating isolated health conditions to a whole-person care model encompassing physical, mental, emotional health and social determinants of health.
- Apex BenefitscoreAyble Health and Apex Benefits partnered to expand access to digestive healthcare. Apex Benefits provides workplace health benefits consulting and will offer Ayble Health as part of their digestive health solution for employer clients.
- Commure EngagesupportingAyble partnered with Commure Engage to connect GI patients with personalized care through integration with Commure's patient engagement platform, enhancing connectivity and care coordination.
- Brigham and Women's HospitalsupportingResearch collaboration with Brigham and Women's Hospital for GI clinical studies. Dr. Joshua Korzenik, Director of the Crohn's & Colitis Center at Brigham & Women's Hospital and Associate Professor of Medicine at Harvard Medical School, serves as a clinical advisor.
- Massachusetts General HospitalsupportingResearch collaboration with Massachusetts General Hospital for GI clinical studies. Dr. Mythili Pathipati, Gastroenterologist at MGH and Stanford School of Medicine, serves as a clinical advisor. MGH is listed as a research partner on the website.
- Northwestern UniversitysupportingResearch collaboration with Northwestern University for GI clinical studies. Dr. Tiffany Taft, Associate Professor of Medicine at Northwestern Feinberg School of Medicine and Founding Member of Rome Foundation Psycho-Gastroenterology Section, serves as a clinical advisor.
- University of WashingtonsupportingResearch collaboration with University of Washington for GI clinical studies, contributing to the evidence base supporting Ayble Health's approach.
- Mayo ClinicsupportingResearch and clinical collaboration with Mayo Clinic. Mayo Clinic logo appears alongside other academic research institutions on the Ayble Health website, indicating a formal research partnership.
- IMAGINE NetworksupportingDr. Paul Moayyedi, Principal Investigator of the IMAGINE network, serves as a clinical advisor. IMAGINE is a clinical research network focused on GI conditions.
Scale indicators13 records
Recent moves6 records
Expansion highlights6 records
Ayble Health competitors and assessment
Company assessmentDirect peers
- Oshi Health: Oshi Health is a virtual-first gastroenterology clinic providing integrated care (dietitians, behavioral health, GI specialists) for IBS, IBD, and related conditions. It is the closest direct competitor to Ayble, sharing the same hybrid D2C + employer/payer + health-system GTM model and recently featured alongside Ayble in IBD management research.
- Vivante Health: Vivante Health offers GIThrive, a digital gut-health platform combining nutrition, behavioral, and clinical care for digestive conditions, sold primarily through employers and health plans. It competes head-to-head with Ayble in the employer/payer benefits channel for GI care.
- Trellus Health: Trellus Health provides a digital therapeutic program for IBD and IBS built on gut-directed hypnosis and resilience training. It overlaps with Ayble's Mind-Gut Program (CBT, GDH, ACT) and shares the same specialty digital therapeutics category for chronic GI conditions.
- metaMe Health: metaMe Health developed Regulora, an FDA-cleared digital therapeutic using gut-directed hypnosis for IBS abdominal pain. It directly competes with Ayble's Mind-Gut program on the digital therapeutics side of GI behavioral care.
- Mahana Therapeutics: Mahana Therapeutics is a digital therapeutics company focused on gut-brain conditions including IBS, with evidence-based behavioral programs. It is a direct competitor in the digital therapeutic category for GI conditions and shares Ayble's gut-directed hypnosis and CBT methodologies.
- Bold Health: Bold Health (formerly Bold Health and later Mahana-branded operations) developed evidence-based digital therapeutic programs for IBS and other GI conditions using CBT and gut-directed hypnotherapy. It competes with Ayble in the digital GI therapeutics category, especially in Europe.
Regional players
- Cara Care: Cara Care is a digital digestive health platform offering personalized nutrition, symptom tracking, and content for conditions like IBS and IBD, primarily in Europe. It is comparable to Ayble in product scope (nutrition + symptom tracking) but does not directly compete in the U.S. enterprise/payer market.
Emerging players
- ModifyHealth: ModifyHealth provides medically tailored meals and nutrition support for GI and other chronic conditions, often sold through employer benefits and providers. It is comparable to Ayble's nutrition-focused offering and shares the employer-channel GTM motion, though its core product is food delivery rather than a digital platform.
Broad incumbents
- GI Alliance: GI Alliance is the largest gastroenterology services network in the U.S., operating hundreds of GI providers and clinics. It is comparable to Ayble as the incumbent clinical GI delivery layer against which Ayble's health system integration and remote patient monitoring platform competes.
Others
- Headspace Health: Headspace Health combines the Headspace mental health app with Ginger's on-demand coaching/therapy. It is adjacent to Ayble's Mind-Gut Program (which uses CBT, ACT, and mindfulness for GI patients) and represents a broader mental health incumbent that could expand into GI-specific behavioral care.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat6 records
Key risks5 records
Key highlights7 records
Customer concentration
Ayble Health social profiles
Digital presenceAyble Health financial estimates
Financial estimateRevenue estimate
Valuation estimate
Ayble Health leadership team
Management profileNumber of profiles
Profiles2 records
Ayble Health funding detail
Funding detailFunding overview
Funding rounds3 records
Investors10 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Ayble Health M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Ayble Health
What does Ayble Health do?
Ayble Health operates a clinically-backed digital health platform that delivers personalized nutrition planning, GI psychology programs (CBT, gut-directed hypnosis, ACT), and access to licensed GI dietitians and health coaches for individuals with gastrointestinal conditions such as IBS and IBD. The platform combines AI-powered personalization from a proprietary GI data ecosystem with a food discovery engine, barcode item scanner, and 2.3 million recipes, and is offered directly to consumers via subscription as well as through employer health benefits, health plan coverage, and health system clinical integrations.
Is Ayble Health a public or private company?
Ayble Health is a private company. It is classified as venture growth investor backed and is currently operating.
When was Ayble Health founded?
Ayble Health was founded in 2020. It employs 11 to 50 people.
Where is Ayble Health based?
Ayble Health is headquartered in Boston, United States, in the North America region.
How does Ayble Health make money?
Three revenue lines are on record. Subscription - Consumer Direct is the primary driver. The others are enterprise B2B - Employer Health Plans and health Insurance Reimbursement.
Who are Ayble Health's main competitors?
Direct peers on record are Oshi Health, Vivante Health, Trellus Health, metaMe Health, Mahana Therapeutics and Bold Health. Cara Care is listed as a regional player. ModifyHealth is listed as an emerging player. GI Alliance is listed as a broad incumbent. Headspace Health is listed as an others.
Does Ayble Health have an API?
No public API is recorded for Ayble Health.
What industry is Ayble Health in?
Ayble Health's product category is Digital Gastrointestinal Care Platform. Its primary akta.pro industry code is HLALAGAE, Gastroenterology Telemedicine Platforms, with a secondary code of HSADAFAE, Medical Nutrition Therapy (Registered Dietitian). Its NAICS code is 5132 and its SIC code is 8000.