Trillium Health

What Trillium Health does

Trillium Health is a nonprofit Federally Qualified Health Center Look-Alike headquartered in Rochester, New York, operating as an integrated community health center that delivers primary care, gynecology, pediatrics, behavioral health, sexual health, HIV prevention and treatment, Hepatitis C care, substance use disorder treatment, and pharmacy services. Founded in 1989 as an HIV/AIDS clinic during the AIDS crisis, Trillium received its FQHC Look-Alike designation in 2016, which provides access to the federal 340B drug discount program and underpins its ability to serve uninsured and underinsured patients regardless of ability to pay. The organization's "three petals" care model — treating physical, emotional, and social health — co-locates clinic, pharmacy, food pantry, and lab services under one roof, supplemented by a 38-foot mobile clinic launched in 2019 and telehealth services.

The organization serves a broad cross-section of underserved populations: LGBTQ+ individuals seeking affirming care, people living with or at risk for HIV, low-income and uninsured patients, seniors (including those aging with HIV through the ARCH program), and children from birth through young adulthood. Notable clinical differentiators include being the only Rochester-area provider with two GeneXpert machines for 45-60 minute Hepatitis C diagnosis (achieving a 93% sustained virologic response cure rate across 456 patients since 2015) and designation as a New York State Hepatitis C Center of Excellence, an NCQA Patient-Centered Medical Home, and an Age-Friendly Health System.

Trillium Health generates revenue through a hybrid model: patient services billed to Medicare, Medicaid, and commercial insurance, supplemented by a sliding fee discount program for uninsured patients, the 340B drug pricing program, and substantial grant funding. Major grants include $3 million from HRSA (November 2024) for operational expansion, $1 million from the City of Rochester (February 2024) for the Food Pharmacy pilot, and $400,000 from the Gilead Foundation (January 2026) for a two-year HIV prevention program. In May 2025, the organization transitioned to the MyChart patient portal integrated with UR Medicine, improving interoperability with the regional health system.

Name

Trillium Health

Legal name

Trillium Health

Website

https://trilliumhealth.org

Company type

Private

Founded year

1989

Operating status

Operating

Headcount range

251–500 employees

Short description

Trillium Health is a nonprofit Federally Qualified Health Center Look-Alike in Rochester, NY, delivering integrated primary care, specialty services, pharmacy, and social support to underserved, LGBTQ+, and HIV-affected populations regardless of ability to pay.

Ownership category

akta.pro rank

Product category

Community Healthcare Services

NAICS

Ambulatory Health Care Services (621), Other Outpatient Care Centers (62149), Health Care and Social Assistance (62)

SIC

Services-Health Services (8000), Services-Specialty Outpatient Facilities, Nec (8093), Services-Offices & Clinics Of Doctors Of Medicine (8011), Services-Social Services (8300)

akta.pro primary industry

Mobile & Street Medicine Primary Care Programs (HLAFAGAH)

akta.pro secondary industry

Care Navigation & Triage-to-Provider Referral Platforms (HLALALAD)

Keywords

• Community health services
• HIV prevention care
• Primary healthcare
• Hepatitis C treatment
• Federally qualified health

Headquarters

HQ city

Rochester

HQ country

United States

HQ region

North America

Offices4 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Supply Chain, Infrastructure, Technology or R&D, Marketing or Sales

Revenue model

1. Patient Services Revenue: Revenue generated from providing healthcare services to patients. Trillium Health accepts a variety of insurance plans including Medicare and Medicaid, and offers sliding fee discounts based on family size and income for uninsured patients.
2. 340B Drug Pricing Program: As an FQHC Look-Alike, Trillium Health purchases prescription medicine at reduced prices through the federal 340B drug discount program, allowing the organization to provide comprehensive healthcare services and medicines at little-to-no cost to patients while generating program revenue.
3. Foundation and Government Grants: Trillium Health receives grant funding from foundations (e.g., Gilead Foundation $400,000 HIV prevention grant) and government sources (e.g., $3 million expansion award, $1 million City of Rochester Food Pharmacy funding) to support specific programs and community health initiatives.

Pricing tiers

Go-to-market motion1 record

Distribution channels6 records

Marketing channels7 records

Core offering

Trillium Health is a Federally Qualified Health Center Look-Alike that delivers integrated primary and specialty medical care (including HIV prevention and treatment, Hepatitis C care, gynecology, pediatrics, behavioral health, and substance use treatment) alongside on-site pharmacy, care management, food pantry, harm reduction, and financial assistance services. Care is delivered through two physical clinic sites, a 38-foot mobile clinic, and telehealth, primarily serving underserved populations in Rochester, NY.

Product overview

Trillium Health is a Federally Qualified Health Center Look-Alike (designated in 2016) offering integrated, personalized primary and specialty medical care. The organization operates a platform-based model combining multiple clinical services including Primary Care, Gynecology, Pediatrics, Sexual Health Services, HIV Prevention and Care, Hepatitis C Care, Behavioral Health, and Substance Use Disorder Treatment. Supporting services include On-Site Pharmacy, Care Management, Food Pantry, Harm Reduction, and Financial Assistance programs. The organization serves diverse communities in Rochester, NY with a focus on underserved populations, providing comprehensive healthcare under one roof.

Differentiator

Problem solved

Functional benefit

Products and services

• Primary Care Comprehensive primary healthcare services including treatment for acute and common conditions, general wellness check-ups, STD/STI and HIV testing and treatment, Hepatitis C care, diabetes management, transgender care, senior care, insurance enrollment assistance, and medically-assisted treatment for substance use disorders. Targeted at individuals and families seeking accessible primary care.
• Gynecology Comprehensive gynecological care including family planning, contraceptive management, minimally invasive laparoscopic and robotic surgeries, pediatric/adolescent gynecologic services, diagnostic ultrasounds, and menopause management. For women across the lifespan.
• Pediatrics (Pathway Pediatrics) Comprehensive pediatric services for children and young adults including routine well-child visits, immunizations, same-day acute visits, developmental screenings, lactation counseling, care management, chronic condition monitoring, emotional and behavioral wellness, and on-site pharmacy services. Includes the Reach Out & Read pediatric literacy program.
• Mobile Clinic A 38-foot mobile clinic equipped with two exam rooms and a waiting area, providing inclusive and barrier-free medical care including treatment for acute conditions, wellness check-ups, HIV/STD/Hep C testing and treatment, and COVID-19 testing by bringing healthcare directly to communities.
• Sexual Health Services Comprehensive sexual health services including a sexual health clinic, routine testing, PEP (post-exposure prophylaxis for HIV), PrEP (pre-exposure prophylaxis), PrEP for women, and sexually transmitted infection testing and treatment, including DoxyPEP.
• HIV Prevention and Care HIV prevention services including PrEP and PEP, routine HIV testing, and comprehensive care for people living with HIV including the Ryan's Connection Center for community and support. Center of Excellence in HIV care.
• Hepatitis C Care Designated Hepatitis C Center of Excellence providing testing and treatment for Hepatitis C, staffed with board-certified infectious disease physicians, pharmacists, and coordinators who guide patients from diagnosis to cure. 93% sustained virologic response rate; 456 patients cured since 2015.
• Behavioral Health Mental health counseling services for children, teens, and adults, available at multiple locations including 259 Monroe Avenue and 170 Science Parkway, as well as through video visits.
• Treatment for Substance Use Disorders

Quantifiable outcome

• 93% of Hepatitis C patients achieve sustained virologic response (SVR), effectively cured
• +3 more outcomes

Named customers5 records

Segments5 records

Ideal customer profiles5 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Five partnerships are on record, tiered core and minor.

• Rochester Hearing & Speech CentercoreStrategic or Co-development Partner · 4 December 2025Partnership to offer free hearing screenings to the community. Adults (18+) could receive free testing and consultation with an on-site audiologist. Funded by Mother Cabrini Health Foundation grant.
• RTS (Rochester Transit System)coreStrategic or Co-development Partner · 26 May 2021Collaboration to hold COVID-19 vaccination clinic at the RTS Transit Center in downtown Rochester, reaching thousands of bus riders. Trillium provided vaccines while RTS provided the venue.
• New York State, Rochester Rapid Response Team, City of Rochester, Monroe County, Common Ground Health, Finger Lakes COVID-19 Vaccine Hub and Task ForcecoreStrategic or Co-development Partner · 26 May 2021Multi-organizational collaboration for COVID-19 vaccination efforts at the RTS Transit Center, combining resources and expertise from state, city, county, and community health organizations.
• FQHC Look-Alike Advocacy CoalitionminorStrategic or Co-development PartnerTrillium Health is a member of the coalition established to raise awareness about Look-Alikes and fight for equal funding compared to fully-funded FQHCs (330 Grantees).
• FoodlinkcoreStrategic or Co-development PartnerBenefit navigators at Foodlink available to help community members understand SNAP work requirement changes and locate food resources including pantries, meal programs, and Pop-Up Pantries.

Scale indicators6 records

Recent moves10 records

Expansion highlights6 records

Direct peers

• Whitman-Walker Health: Washington, D.C. community health center specializing in LGBTQ+ care, HIV/AIDS services, and primary care. Comparable mission, patient population, and integrated medical/social services model.
• Fenway Health: Boston-based FQHC specializing in LGBTQ+ care, HIV prevention/treatment, and primary care. Comparable specialty focus on LGBTQ+ and HIV populations, integrated pharmacy, and research enterprise.
• Ryan Health: New York City FQHC network providing primary care, behavioral health, and HIV services to underserved Manhattan communities. Comparable as a multi-site community health center with HIV specialty programs and integrated support services.
• Sun River Health: Large New York State FQHC operating primary care, specialty care, and community-based services across multiple counties. Comparable as a multi-site community health center serving diverse and underserved populations with integrated medical, behavioral, and support services.
• Howard Brown Health: Chicago-based FQHC with LGBTQ+ primary care, HIV services, and women's health. Comparable patient demographics, multi-site community health model, and integrated behavioral and pharmacy services.
• Callen-Lorde Community Health Center: New York City FQHC specializing in LGBTQ+ primary care, HIV prevention and treatment, and affirming care. Directly comparable to Trillium's LGBTQ+ and HIV specialty focus, integrated pharmacy, and sliding-fee model.
• Chase Brexton Health Care: Maryland FQHC providing primary care, behavioral health, and HIV specialty services across multiple sites. Comparable as a multi-site FQHC with strong HIV/LGBTQ+ programs and integrated pharmacy.
• Community Health Center of Buffalo: New York State FQHC operating primary care, pediatrics, behavioral health, and supportive services in western New York. Comparable as a regional FQHC serving Medicaid and uninsured populations in Upstate NY.

Broad incumbents

• UR Medicine (University of Rochester Medical Center): Major academic medical center in Rochester. Functions as a strategic partner (MyChart integration) and a competitor for specialty care referrals, but operates as a broad incumbent across the full clinical spectrum rather than focusing on underserved community health.
• Rochester Regional Health: Dominant regional health system serving the greater Rochester area. Overlaps with Trillium on primary care, pediatrics, and behavioral health, but operates as a broad incumbent with inpatient services and specialty care at a much larger scale.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/TrilliumNY

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles10 records

Subsidiaries2 records

Funding overview

Funding rounds3 records

Investors2 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Trillium Health