Mindset Health

What Mindset Health does

Mindset Health is an Australian-headquartered digital therapeutics company that develops AI-powered, app-delivered hypnotherapy and brain-body behavioral programs for chronic conditions where pharmacology underperforms. The company's portfolio comprises four commercial programs — Nerva for IBS and functional dyspepsia (built with Dr. Simone Peters at Monash University), Evia for menopausal hot flashes (built with Dr. Gary Elkins at Baylor), Claria for anxiety, depression, and stress (developed with Dr. Michael Yapko), and Relio for chronic primary pain (developed with NeuRA) — each delivered via iOS and Android apps in 70+ countries to 350,000+ patients. The platform applies AI to personalize content sequencing and audio delivery based on symptom tracking, preferences, and engagement patterns, while the underlying clinical protocols are pre-authored by named academic founders and validated in peer-reviewed randomized controlled trials, including an AJG 2025 RCT (n=244) demonstrating efficacy against an active control for IBS.

The business operates a hybrid go-to-market model. Consumer revenue comes from annual subscriptions purchased via the App Store, Google Play, and program-specific websites, with a 25% automatic discount for practitioner-referred patients. Enterprise revenue comes from outcome-aligned contracts with US health plans and payers, structured around pre-agreed symptom-reduction thresholds with symmetric risk, modeled at $500 per enrolled member per year with a 5.2x gross-to-cost ratio, and deployed to 136,000+ US members through commercial, Medicare Advantage, and ASO books. The company was selected for the CMS ACCESS Model in 2026 for MSK and behavioral health tracks. A referring-provider channel of 20,000+ clinicians globally (8,700+ in the US) drives bottom-up clinical adoption via EHR order sets, e-referral, and secure web forms, with patient-reported outcome measures fed back to clinicians at weeks 6, 12, and 24. Mindset Health is HIPAA- and SOC 2 Type II-compliant, operates from Melbourne (HQ) and New York (US commercial office), and has raised approximately $19.65M across four disclosed funding rounds including a $12M Series A in March 2023 led by King River Capital.

Name

Mindset Health

Legal name

Mindset Health Pty Ltd

Website

https://mindsethealth.com

Company type

Private

Founded year

2019

Operating status

Operating

Headcount range

11–50 employees

Short description

Mindset Health develops AI-personalized, app-delivered hypnotherapy and brain-body programs for chronic IBS, menopause, anxiety, and pain conditions. It sells annual consumer subscriptions and outcome-aligned contracts to US health plans, serving 350,000+ patients across 70+ countries.

Ownership category

akta.pro rank

Product category

Digital Therapeutics

NAICS

Offices of Mental Health Practitioners (except Physicians) (621330), Outpatient Mental Health and Substance Abuse Centers (621420)

SIC

Services-Prepackaged Software (7372), Services-Health Services (8000)

akta.pro primary industry

Behavioral Health & Neurocognitive Therapeutics (Digital) (HLACANAI)

akta.pro secondary industries

General Mental Health Therapy Platforms (Talk Therapy) (HLALAEAA), Meditation Apps, Digital Courses & Online Communities (HSADAJAH), Healthcare & Wellness Personalization (HDAAAGAI)

Keywords

• Digital therapeutics
• Hypnotherapy apps
• Gut-directed hypnotherapy
• Brain-body behavioral programs
• Chronic condition management

Headquarters

HQ city

Melbourne

HQ country

Australia

HQ region

Oceania

Offices2 records

Markets served

GTM type

B2B and B2C

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Annual Program Subscription: Each program is offered as an annual subscription. Individual consumers purchase direct. Practitioner-referred patients receive an automatic 25% discount. Health plan and employer coverage is contracted separately. Comparable in cost to a single specialist session. Patient Assistance Program available for those facing financial hardship.
2. Health Plan and Payer Contracts: Outcome-aligned commercial contracts with health plans and payers tied to pre-agreed symptom-reduction thresholds. Symmetric risk structure with withholding on the company side. CMS ACCESS-aligned contracts for Medicare and commercial books. Program cost modeled at $500/year per enrolled member with estimated gross-to-cost ratio of 5.2x.

Pricing tiers

Go-to-market motion4 records

Distribution channels5 records

Marketing channels7 records

Core offering

Mindset Health sells AI-powered mobile-app digital therapeutics that deliver clinically validated brain-body behavioral programs — primarily gut-directed hypnotherapy and related techniques — for chronic conditions including IBS, menopause symptoms, chronic primary pain, and anxiety/depression. Each program runs over 5-6 weeks with daily audio sessions, lessons, and exercises that AI-personalizes to the user's symptoms, progress, and engagement, and is sold either as an annual consumer subscription or via outcome-aligned contracts to health plans, payers, and employers.

Product overview

Mindset Health is a digital therapeutics company offering AI-powered brain-body behavioral programs delivered through mobile apps. The portfolio consists of four distinct commercial products: Nerva (gut/brain program for IBS and functional dyspepsia), Evia (menopause program for vasomotor symptoms), Claria (mental health program for anxiety, depression, and stress), and Relio (pain program for chronic primary pain). All programs share the same underlying therapeutic model—digitally delivered hypnotherapy and brain-body techniques—which adapts to each user's symptoms, goals, and progress. Programs are built with academic partners (Monash University, Baylor University, NeuRA) on protocols validated in peer-reviewed randomized controlled trials and delivered via subscription mobile apps.

Differentiator

Problem solved

Functional benefit

Brands

• Nerva: A six-week gut-brain behavioral program for people with IBS. Built with Dr Simone Peters from Monash University, it delivers gut-directed hypnotherapy via a mobile app.
• Evia
• Claria
• Relio

Products and services

• Nerva A six-week AI-personalized gut-brain behavioral program delivered via mobile app for adults with IBS and functional dyspepsia, delivering gut-directed hypnotherapy with guided mental imagery, psychoeducation, and adherence support to recalibrate the brain-gut axis. Validated in the AJG 2025 RCT (n=244) against an active control.
• Evia A five-week non-hormonal, AI-personalized digital program for hot flashes, night sweats, and broken sleep associated with menopause, designed for women who cannot or prefer not to use hormone therapy (including breast cancer patients). 76% of participants reported ≥50% reduction in daily hot flashes in a real-world cohort (Scheffrahn, JMIR 2025, n=139).
• Claria Short, daily AI-personalized sessions delivered via mobile app that help adults manage the autonomic and cognitive patterns behind anxiety, depression, and everyday stress. Developed with Dr Michael Yapko using his autonomic and cognitive regulation approach to clinical hypnosis.
• Relio A six-week AI-personalized pain reprocessing program for chronic primary pain (including chronic back pain and fibromyalgia) where structural disease has been ruled out or stabilized, helping patients reinterpret persistent pain signals as safe rather than threatening. Developed with NeuRA.

Quantifiable outcome

• 81% of participants met IBS-SSS responder threshold at 6 weeks, vs. 63% on active control (AJG 2025, n=244)
• +6 more outcomes

Named customers3 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

AI capability6 records

Feature5 records

Partnerships

Nine partnerships are on record, tiered core and supporting.

• Monash UniversitycoreStrategic or Co-development PartnerMindset Health collaborates with Monash University on research and protocol development. Dr Simone Peters, a Monash University researcher and founder of the Mind + Gut Clinic, developed the gut-directed hypnotherapy protocol that became Nerva. Research collaboration includes a founding-protocol RCT (Peters 2016, Alimentary Pharmacology & Therapeutics) and ongoing DGBI expansion research. Monash University is a key research partner shown in logos across the website.
• Baylor UniversitycoreStrategic or Co-development PartnerDr Gary Elkins, Professor of Psychology and Neuroscience at Baylor University and director of the Mind-Body Medicine Research Laboratory, is the content founder for Evia (menopause program) and Finito. He is the senior author of foundational hypnosis trials for menopausal hot flashes, including a 2013 RCT in Menopause. The company cites this collaboration as the basis for the Evia menopause program.
• Massachusetts General HospitalsupportingStrategic or Co-development PartnerMassachusetts General Hospital is listed as a research partner on the Mindset Health website. Dr Kyle Staller, Director of the GI Motility Laboratory at Mass General and Associate Professor of Medicine at Harvard Medical School, serves on the Clinical Advisory Board.
• Mayo ClinicsupportingStrategic or Co-development PartnerMayo Clinic is listed as a research partner on the Mindset Health website, alongside other leading academic medical centers (Monash, Mass General, Mount Sinai, NeuRA).
• Mount SinaisupportingStrategic or Co-development PartnerMount Sinai is listed as a research partner on the Mindset Health website, alongside other leading academic medical centers.
• NeuRA (Neuroscience Research Australia)coreStrategic or Co-development PartnerNeuRA collaborated with Mindset Health on the development of Relio, a six-week pain reprocessing program for chronic primary pain. NeuRA is an Australian neuroscience research institute and a key partner in the pain program. Listed as a research partner across the website.
• Dr Michael YapkocoreStrategic or Co-development PartnerDr Michael Yapko, a clinical psychologist known for pioneering strategic, outcome-focused psychotherapies and advanced clinical hypnosis, is the content founder for Claria (mental health program). He has authored more than a dozen books and is a worldwide lecturer. Dr Yapko developed the autonomic and cognitive regulation approach used in Claria.
• HIF Health InsurancesupportingGTM or Marketing PartnerHIF Health Insurance partnered with Mindset Health to provide digital hypnotherapy programs to their insured members. This partnership was noted in a market overview of the U.S. Complementary and Alternative Medicine market as a key recent development, expanding access to Mindset's digital therapeutic programs through a health insurance channel.
• Alfred HealthsupportingStrategic or Co-development PartnerAlfred Health in Melbourne is affiliated with Dr Simone Peters' research and the gut-directed hypnotherapy protocol development. Dr Peters conducts research with both Alfred Health and Monash University. The protocol developed at these institutions became the basis for Nerva.

Scale indicators13 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• Kaia Health: Digital MSK and chronic pain platform with employer/payer distribution. Comparable in chronic pain to Relio and in self-guided mobile delivery model to Mindset Health's broader portfolio.
• Sword Health: Digital MSK and pelvic health platform with AI-powered programs. Competes with Relio on chronic pain and was also selected for CMS ACCESS in MSK, making it a direct comparator in the enterprise and federal outcome-aligned contracting landscape.
• Hinge Health: Largest digital MSK and pain player with deep employer and payer contracts. Comparable to Mindset's Relio program in chronic pain; selected by CMS for ACCESS in MSK alongside Mindset, making it a direct competitor in the same federally-aligned outcome-paid channel.
• Headspace Health: Mental wellness platform combining meditation, mindfulness, and therapy (Ginger). Overlaps with Claria on anxiety, depression, and stress; comparable in B2B employer/payer distribution and consumer app-store delivery.

Direct peers

• Akili Interactive: Digital therapeutics company (EndeavorRx, etc.) delivering FDA-cleared software-based cognitive therapeutics. Closely comparable as a prescription digital therapeutic pursuing payer coverage with evidence-based outcomes, though focused on cognition rather than brain-body behavioral therapy.
• metaMe Health: Digital therapeutics company focused on gut-brain conditions including IBS. Competes head-to-head with Mindset Health in digital gut-directed hypnotherapy and shares the same regulatory and payer-contract pathway.
• Mahana Therapeutics: Direct competitor in digital therapeutics for IBS. Mahana's product (Regulora/H家的) targets the same gut-directed hypnotherapy indication as Nerva with a similar mobile-delivered model, making it the closest functional competitor in the IBS DTx category.
• Big Health: Digital therapeutics company (Sleepio for insomnia, Daylight for anxiety) delivering automated cognitive behavioral therapy via mobile apps. Closely comparable in business model, evidence standards, payer contracting, and chronic-condition focus.
• Bold Health (Cara Care): Digital therapeutic platform for digestive conditions including IBS. Competes with Nerva in the same indication through a mobile-app delivery model combining behavioral therapy, education, and tracking — same patient population and provider channel.

Emerging players

• Calm: Consumer meditation and sleep app with growing enterprise/B2B distribution. Adjacent to Claria in stress and sleep; comparable in mobile subscription model and consumer self-enrollment motion, though positioned as wellness rather than digital therapeutic.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks7 records

Key highlights7 records

Customer concentration

• Xx.com/mindsethealth
• YouTubeyoutube.com/watch?v=8YCVqDb0scQ
• Facebookfacebook.com/mindsethealth
• LinkedInlinkedin.com/company/mindsethealth
• Instagraminstagram.com/mindsethealth

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds4 records

Investors15 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Mindset Health