Bio Essence

What Bio Essence does

Bio Essence, operating as BIO ESSENCE CORP (OTC Pink: BIOE), is a US-based Traditional Chinese Medicine (TCM) supplement company headquartered in Irvine, California, with 20+ years of operating history and 11-50 employees. The company manufactures and sells a portfolio of approximately 20+ branded dietary supplements and TCM herbal products across categories including bone and joint health, cardiovascular health, cognitive function, digestive health, immune support, kidney and liver health, men's health, optic health, sleep, and women's health. Core technical differentiators include a 12-step quality control process, GMP-certified manufacturing, third-party testing with Certificate of Analysis documentation, and a 5:1 extract ratio for mushroom-based supplements providing concentrated beta-glucans and polysaccharides.

The company operates a hybrid go-to-market model. Direct-to-consumer revenue flows through bioessence.com with same-day delivery and retail unit pricing of $19.80-$59.80 per product. A dedicated practitioner portal (pro.bioessence.com) serves TCM practitioners, acupuncturists, and licensed healthcare professionals with practitioner-specific registration and pricing. Distribution is amplified through four named professional supplement partners — Emerson Ecologics, Goldenneedle, Acu-market, and LhasaOMS — extending reach into the integrative medicine channel. A B2B/private-label layer supplies gyms, health food stores, supplement retailers, TCM clinics, and e-commerce sellers with wholesale pricing, custom formulation manufacturing, and flexible minimum order quantities, accompanied by full quality documentation.

Bio Essence is publicly traded on the OTC Pink market and in February 2026 announced a Regulation A Tier 2 offering to raise up to $5 million (100 million shares at $0.05 per share) to fund an AI-enabled health platform initiative encompassing telemedicine, diagnostic tools, and personalized nutrition. In April 2026 the company acquired MediFlow AI for approximately $3.5 million, signaling a strategic pivot from a pure-play supplement brand toward a tech-enabled health services model. Current AI capabilities are pre-revenue and rely on the acquired MediFlow AI entity for technical execution.

Name

Bio Essence

Legal name

BIO ESSENCE CORP

Website

https://bioessence.com

Company type

Public

Founded year

2004

Operating status

Operating

Headcount range

1–10 employees

Short description

Bio Essence is a US-based TCM herbal supplement company (OTC Pink: BIOE) that manufactures and sells 20+ branded dietary supplements to consumers, TCM practitioners, and B2B/private-label buyers, and is pivoting toward an AI-enabled health platform.

Ownership category

akta.pro rank

Product category

Dietary Supplements

NAICS

Medicinal and Botanical Manufacturing (325411), Food (Health) Supplement Retailers (456191)

SIC

Medicinal Chemicals & Botanical Products (2833)

akta.pro industry

PRIMARYCRADAGAD

Herbal & Botanical Supplements

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/Vitamins, Supplements & Sports Nutrition

SECONDARYCRADAGAE

Specialty Condition Supplements (Sleep, Stress, Heart, Joint, Gut, Immunity)

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/Vitamins, Supplements & Sports Nutrition

SECONDARYCRADAGAM

Healthy Aging & Cognitive Support Supplements

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/Vitamins, Supplements & Sports Nutrition

SECONDARYCRADAGAL

Men’s Health Supplements (Testosterone, Prostate, Vitality)

Consumer Products & Retail/Consumer Packaged Goods (CPG) Manufacturing & Brands/Vitamins, Supplements & Sports Nutrition

SECONDARYEUAAAIAK

Bio-based Pharmaceuticals, Nutraceuticals & Specialty Bioactives

Energy, Utilities & Environment/Bioenergy, Natural Gas & Biomass/Biorefining & Bio-based Chemicals (Co-products, Bioproducts)

Keywords

• Herbal supplements
• Traditional Chinese Medicine
• Dietary supplements
• TCM herbs
• Private label supplements

Headquarters

HQ city

Newport Beach

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Marketing or Sales, Technology or R&D, Infrastructure

Revenue model

1. Direct Product Sales: Bio Essence generates revenue through direct-to-consumer sales of TCM herbs, herbal supplements, and health products via their e-commerce website. Products are sold at unit pricing ranging from approximately $19.80 to $59.80 per unit, with same-day delivery available.
2. Wholesale and B2B Services: The company offers wholesale pricing to gyms, personal trainers, health food stores, supplement retailers, TCM clinics, and e-commerce sellers. Private label packaging and custom formula manufacturing services are available with flexible minimum order quantities.
3. Online Pharmacy Services: Bio Essence provides online pharmacy services, allowing customers to order products through their digital platform with home delivery options.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels4 records

Core offering

Bio Essence manufactures and sells Traditional Chinese Medicine (TCM) herbal supplements, single herbs, and formula herbs targeting bone/joint, cardiovascular, cognitive, digestive, immune, kidney/liver, men's, optic, sleep, and women's health. The company sells direct-to-consumer through its e-commerce website and to healthcare practitioners and retailers through a dedicated practitioner portal, wholesale, and private-label services.

Product overview

Bio Essence Health Science is a US-based supplement company offering Traditional Chinese Medicine (TCM) herbs and health supplements. The product portfolio includes TCM single herbs and formula herbs, along with approximately 20+ vitamin and health supplements organized into categories: Bone & Joint Health (Bone Density Enhancer, Powerful Joint), Cardiovascular Health (Powerful Heart, Red Yeast Rice Plus), Cognitive Health (Memory Plus), Digestive Health (Full Spectrum Enzymes), Immune Health (Cordyceps Mushroom, Mushroom King, Viral Defense, Allergy & Sinus Support), Kidney & Liver Health (Kidney Plus, Liver Plus), Men's Health (Energy Plus, RejuProsta), Optic Health (Eye Plus), Sleep Health (Sleep Plus), Women's Health (Menopause Plus, Collagen Plus, Fat Burner Plus, Happy Mood). The company also provides services including an Online Pharmacy and Custom Formulation for practitioners. Products are GMP-certified and sold primarily through the company's e-commerce platform and distributor network.

Differentiator

Problem solved

Functional benefit

Products and services

• Bone Density Enhancer Bone health supplement supporting calcium absorption and bone mineralization through vitamin D and minerals including zinc, selenium, and magnesium citrate; sold in 150 capsules at $29.80.
• Powerful Joint (Capsules) Joint support supplement combining BioCell Collagen Type II and natural glucosamine HCL to support connective tissues and reduce joint discomfort.
• Powerful Joint (Tablets, Large) Joint health supplement in tablet form providing cartilage support and mobility enhancement through collagen and glucosamine extracts; 180 tablets at $59.80.
• Powerful Joint (Tablets, Small) Smaller-size variant of Powerful Joint tablets with BioCell Collagen Type II and glucosamine HCL for cartilage support; 60 tablets at $29.80.
• Powerful Heart Cardiovascular supplement featuring a proprietary blend of 9 herbs with magnesium and CoQ10 to support vascular health and healthy blood pressure.
• Red Yeast Rice Plus Cholesterol support supplement combining red yeast rice extract, CoQ10, Chinese Hawthorn, Chinese Salvia, and Milk Thistle to reduce LDL production and support cardiovascular health.
• Memory Plus Cognitive health supplement supporting healthy blood flow to the brain with Ginkgo Biloba Extract, Citicoline, N-Acetyl-L-Tyrosine, Clubmoss Extract, and Phosphatidylserine.
• Full Spectrum Enzymes Digestive support supplement designed to support digestive function, strengthen fat and carbohydrate breakdown, and modulate body enzyme functions.
• Cordyceps Mushroom (Capsules) Energy and stamina supplement using cordyceps mushroom extract to combat fatigue while supporting healthy adrenal and respiratory functions; 120 veggie capsules at $27.80.
• Cordyceps Mushroom Powder Granular cordyceps supplement supporting strength, stamina, immune responses, adrenal function, and respiratory health.
• Mushroom King Immune support supplement featuring extracts from seven medicinal mushrooms (Shiitake, Lion's Mane, Reishi, Agaricus, Cordyceps, Coriolus, Maitake) with amino acids for liver, brain, and immune function.
• Viral Defense Immune system support supplement containing vitamins B, C, D, L-lysine, zinc, and chrysanthemum extract to promote healthy immune function and respiratory health; 75 veggie capsules at $21.80.
• Allergy & Sinus Support Respiratory health supplement utilizing a formula of rhizomes and radix to support and strengthen respiratory systems and immunity functions.
• Kidney Plus Kidney support supplement formulated with Chinese herbs including Jin Qian Cao, Che Qian Zi, Fu Ling, and Ze Xie to enhance kidney function and urinary system health.
• Liver Plus Liver health supplement with N-Acetyl-L-Cysteine, Berberine, Green Tea, Milk Thistle Extract, Dandelion, Turmeric, Schisandra, and Alpha-Lipoic Acid for liver detoxification; 90 capsules at $23.80.
• Energy Plus Stimulant-free energizer supplement featuring American Ginseng and Horny Goat Weed to combat fatigue, reduce stress, and support vitality and libido.
• RejuProsta Men's health supplement combining ancient herbal formulas and modern nutritional research to support healthy urination and prostate function; 90 capsules at $25.80.
• Eye Plus Eye health supplement containing zeaxanthin, lutein, and vitamin A with herbal extracts to maintain optimal eye health and support healthy vision.
• Sleep Plus Sleep support supplement featuring saffron extract, valerian, GABA, and chamomile to promote mental tranquility and healthy sleep patterns; 60 capsules at $19.80.
• Collagen Plus Anti-aging supplement supporting skin health, joint function, and collagen production with herbal extracts, natural vitamins, minerals, and coenzymes; 60 capsules at $32.80.
• Fat Burner Plus Natural thermogenic weight management supplement with green tea extract, garcinia cambogia, cayenne pepper, turmeric, bitter orange, and ginger for metabolism support and appetite control; 100 capsules at $39.80.
• Happy Mood Mood support supplement designed for individuals experiencing stress or anxiety, promoting emotional balance and well-being.
• Menopause Plus Women's health supplement moderating hormone balance through antioxidants, nutrients, vitamins, and herbal extracts to support healthy serotonin production and mood.
• TCM Single Herbs Catalog of Traditional Chinese Medicine single herbs for various health needs, sold through the Bio Essence e-commerce platform.
• TCM Formula Herbs Traditional Chinese Medicine herbal formulas combining multiple herbs for synergistic health benefits.
• Online Pharmacy Online pharmacy service enabling customers to order supplements and health products through the Bio Essence digital platform with home delivery.
• Custom Formulation Service Custom formula manufacturing service allowing practitioners and B2B buyers to create personalized supplement formulations, including private-label packaging with flexible minimum order quantities.
• Wholesale and Private Label Program B2B wholesale pricing and private label packaging services for gyms, health food stores, supplement retailers, TCM clinics, fitness centers, health coaches, and e-commerce sellers with flexible minimum order quantities and full documentation (Certificate of Analysis, third-party testing, GMP certification).

Quantifiable outcome

• Products manufactured in GMP-certified facilities with third-party testing and Certificate of Analysis documentation
• +1 more outcomes

Named customers4 records

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature2 records

Partnerships

Four partnerships are on record, tiered core.

• GoldenneedlecoreChannel Partner/ Reseller/ DistributorGoldenneedle (goldenneedleonline.com) is an online distributor of Bio Essence capsules and supplements. They represent a key channel partner in the professional TCM practitioner market.
• Acu-marketcoreChannel Partner/ Reseller/ DistributorAcu-market is an acupuncture supply marketplace that carries Bio Essence products, serving acupuncturists and TCM practitioners.
• Emerson EcologicscoreChannel Partner/ Reseller/ DistributorEmerson Ecologics is a major professional supplement distributor serving practitioners across North America. They carry Bio Essence products as part of their professional-grade supplement offerings.
• LhasaOMScoreChannel Partner/ Reseller/ DistributorLhasaOMS is a TCM supplies distributor carrying Bio Essence products for their practitioner customer base.

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Emerson Ecologics: The largest US distributor of professional-grade supplements to integrative and TCM practitioners. Comparable because it serves the same practitioner channel that Bio Essence depends on for B2B distribution, and its catalog includes many overlapping botanical and TCM brands.
• Gaia Herbs: Larger US botanical/herbal supplement brand with certified organic herbs, GMP manufacturing, and broad retail and practitioner distribution. Comparable in herbal product positioning and quality certification, but at significantly greater scale and brand recognition.
• Standard Process: Large practitioner-only whole food and herbal supplement brand serving chiropractors, NDs, and integrative practitioners. Comparable in the practitioner-exclusive B2B model and quality positioning, though much larger and broader in scope.
• Metagenics: Major practitioner-channel nutritional supplement company offering a wide range of condition-specific formulations. Comparable as a quality-positioned supplement brand reliant on practitioner recommendations, though operating at far greater scale.

Direct peers

• KPC Herbs: A Taiwan/US TCM herb manufacturer with GMP-certified granule herbs distributed through the same practitioner channels (including LhasaOMS). Direct competitor in the TCM single-herb and formula category with overlapping practitioner customer base.
• ActiveHerb: US-based TCM concentrate and granule herb brand targeting both practitioners and consumers. Direct peer in the standardized TCM extract category with similar 5:1-concentration positioning and practitioner pricing programs.
• Mayway: Long-established US importer and distributor of Chinese herbs and formulas serving TCM practitioners. Comparable product assortment (single herbs, formulas) and channel (practitioner B2B plus direct), making it a direct peer.
• Herb Pharm: US herbal extract manufacturer focused on liquid herbal extracts with strong practitioner and natural-products retail presence. Comparable as a GMP-certified, herb-focused supplement brand with overlapping practitioner channel.

Emerging players

• DAO Labs: Modern TCM-inspired supplement brand targeting mainstream US consumers with mushroom and adaptogen formulations. Comparable as a TCM-heritage-meets-modern-positioning peer, though focused on younger consumer segments.
• Care/of: Direct-to-consumer personalized vitamin and supplement company with a quiz-driven recommendation engine and subscription model. Relevant comparable for Bio Essence's stated AI-personalized-nutrition ambitions, though Care/of is DTC-first and not TCM-rooted.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• Xx.com/essencebio
• YouTubeyoutube.com/watch?v=eCx0PC8s4w8&list=PLYXliOjUZ7drbeKj28xMzUZAD6ZPnldWQ&index=1
• Facebookfacebook.com/bioessencehealthscience/?modal=admin_todo_tour
• LinkedInlinkedin.com/company/bio-essence-inc.
• Instagraminstagram.com/bioessence_healthscience

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds1 record

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Bio Essence