NeurOptics
NeurOptics manufactures automated infrared pupillometers and the proprietary Neurological Pupil index (NPi) algorithm, selling the NPi-300 device, SmartGuard disposable, and NPi-Connect EMR hub to neuro-ICUs, emergency departments, and applied research customers across 50+ countries.
- Company typePrivate
- Founded1995
- HeadquartersLaguna Hills, United States
- Headcount1–10
- GTM typeB2B
- OfferingHardware or Manufacturing
What NeurOptics does
NeurOptics is a privately held US medical device company, incorporated in California and headquartered in Irvine, that develops automated quantitative pupillometry systems used to objectively measure pupillary size and reactivity in critically ill patients. The company's core technology combines an infrared camera and proprietary Vertex Invariant Pupillometry (VIP) signal processing with the Neurological Pupil index (NPi) algorithm — a 0-4.9 numeric scale that compares a patient's pupillary light reflex measurements against a proprietary normative database built over 20+ years. Flagship products include the NPi-300 and NPi-200 handheld pupillometers for clinical use, the single-patient-use SmartGuard disposable for data capture and EMR upload, and the NPi-Connect connectivity hub introduced commercially in early 2025 to streamline EMR integration. The company also sells research-grade instruments (VIP-400 and PLR-4000) to pharmaceutical companies, contract research organizations, and academic institutions.
NeurOptics' primary customers are hospitals and academic medical centers using NPi pupillometry in neuro-ICUs, emergency departments, and other critical care settings, with named adopters including Vanderbilt University Medical Center, Inova Health System, UPMC, CHOP, and UC Irvine Health. Revenue is generated through capital equipment sales of the pupillometers, recurring consumable revenue from the SmartGuard disposable used per patient encounter, and applied research instrument sales. The company sells via a direct sales force and RN Clinical Specialists in North America and through an appointed distributor network covering 50+ countries. NPi pupillometry is supported by 100+ peer-reviewed publications and is referenced in major clinical guidelines including the American Heart Association, Neurocritical Care Society, American College of Surgeons 2024 TBI Best Practices, and ELSO 2025 ECMO Consensus Guidelines.
NeurOptics firmographics
Firmographics- Name
- NeurOptics
- Legal name
- NeurOptics, Inc.
- Website
- https://neuroptics.com
- Company type
- Private
- Founded year
- 1995
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- NeurOptics manufactures automated infrared pupillometers and the proprietary Neurological Pupil index (NPi) algorithm, selling the NPi-300 device, SmartGuard disposable, and NPi-Connect EMR hub to neuro-ICUs, emergency departments, and applied research customers across 50+ countries.
- Ownership category
- akta.pro rank
NeurOptics industry classification
Industry- Product category
- Medical Pupillometry Devices
- NAICS
- Electromedical and Electrotherapeutic Apparatus Manufacturing (334510), Surgical and Medical Instrument Manufacturing (339112), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (33451)
- SIC
- Electromedical & Electrotherapeutic Apparatus (3845), Surgical & Medical Instruments & Apparatus (3841), Optical Instruments & Lenses (3827)
- akta.pro primary industry
- Neurological Monitoring (EEG, Seizure/Sleep/Neuro Wearables) (HLAHACAE)
- akta.pro secondary industries
- Visual Field & Functional Vision Testing (Perimetry, ERG/VEP, Contrast Sensitivity) (HLAHAJAC), Neuro-Ophthalmology (HLAKAKAH)
Keywords
Where NeurOptics is headquartered
LocationHeadquarters
- HQ city
- Laguna Hills
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
NeurOptics business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Supply Chain, Technology or R&D, Personnel, Marketing or Sales, Operations
Revenue model
- Hardware Sales (Pupillometers): Sale of NPi pupillometer devices (NPi-300, NPi-200) to hospitals and healthcare facilities. These are capital equipment purchases typically managed through procurement processes.
- Disposable SmartGuard: Single-patient-use disposable SmartGuard devices that attach to pupillometers for patient data storage. This creates recurring consumable revenue as each patient requires a new SmartGuard.
- Applied Research Products: Sale of research-grade pupillometers (VIP-400, PLR-4000) to pharmaceutical companies, contract research organizations, and academic institutions for clinical research applications.
Go-to-market motion1 record
Distribution channels3 records
Marketing channels7 records
NeurOptics product offering
Product offeringCore offering
NeurOptics manufactures and sells automated infrared pupillometers that objectively measure pupil size and reactivity in critical care and emergency settings, scoring results on its proprietary Neurological Pupil index (NPi) scale. Its core commercial offering centers on the NPi-300 and NPi-200 handheld pupillometers, supported by single-patient-use SmartGuard disposables and the NPi-Connect EMR connectivity hub, with separate research-grade devices (VIP-400, PLR-4000) sold for ophthalmic and pharmaceutical research applications.
Product overview
NeurOptics offers a portfolio of pupillometry products centered on automated quantitative pupillary assessment. The core clinical products are the NPi-300 and NPi-200 Pupillometers, which measure pupil size and reactivity using infrared technology and report results as the Neurological Pupil index (NPi). The SmartGuard is a single-patient-use disposable that stores patient data and enables EMR integration. NPi-Connect is a connectivity hub that facilitates seamless data transfer of NPi measurements into electronic medical records. For applied research, NeurOptics offers the VIP-400 (using Vertex Invariant Pupillometry for refractive surgery and research) and PLR-4000 (for pharmaceutical and academic research). All clinical products use the proprietary NPi scale for objective neurological assessment.
Differentiator
Problem solved
Functional benefit
Products and services
- NPi-300 Pupillometer Flagship handheld automated infrared pupillometer that objectively measures pupil size and reactivity, reporting results on the proprietary Neurological Pupil index (NPi) 0–4.9 scale; Class 1 FDA 510(k)-exempt, CE-marked for adults and children, with a 2-year warranty. Sold to hospitals and ICUs for neurological assessment of critically ill patients.
- NPi-200 Pupillometer Previous-generation handheld automated pupillometer providing objective pupillary assessment and NPi measurement, with Bluetooth connectivity, a customizable trending screen, and EMR compatibility; still sold and supported by NeurOptics.
- SmartGuard Disposable Single-patient-use disposable smart-card device with Mifare 4K RFID that stores 168 paired pupil measurements and a unique patient identifier, enabling HIPAA-compliant data storage and EMR upload when used with the NPi pupillometers.
- NPi-Connect Connectivity Hub SmartGuard connectivity hub that enables seamless data transfer of NPi and pupillary measurements into the hospital EMR, with Light Ring upload status indicators (white/blue/green) and wired ethernet or wireless connectivity options.
- VIP-400 Pupillometer Research-grade pupillometer using proprietary Vertex Invariant Pupillometry (VIP) technology that compensates for vertex distance variance and accounts for pupillary noise; targeted at refractive surgery/LASIK pre-operative evaluation, autonomic neuroscience, and clinical research applications.
- PLR-4000 Pupillometer Research pupillometer used by universities, pharmaceutical companies, and contract research organizations worldwide; offers adjustable light stimulus intensity, duration, and onset with 0.03mm accuracy for high-precision pupillometry research.
Quantifiable outcome
- Nurses save average 19.8 minutes per patient per day using automated pupillometry with direct EMR upload
- +4 more outcomes
Companies that use NeurOptics
Customer profileNamed customers5 records
Segments3 records
Ideal customer profiles2 records
NeurOptics technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration4 records
AI capability3 records
Feature5 records
NeurOptics partnerships and signals
Strategic signalPartnerships
Eleven partnerships are on record, tiered standard and core.
- eServices Medical SASstandardInternational distributor for Critical Care products covering Argentina, Chile, Colombia, Ecuador, Paraguay, Peru, Uruguay, and Latin American markets.
- JR Medical SuppliesstandardInternational distributor for Critical Care products in Australia.
- Surgi-One Medical TechnologiesstandardInternational distributor for Critical Care products in Canada.
- Unidas MedicalstandardInternational distributor for Critical Care products in Brazil.
- Unimedtec GmbHstandardInternational distributor for Critical Care products in Germany and Switzerland.
- IMI Co.standardInternational distributor for Critical Care products in Japan.
- Palex Medical, S.A.standardInternational distributor for Critical Care products in Spain.
- TriLas Medical GmbHstandardInternational distributor for Applied Research products covering Germany and European markets.
- Capsule TechnologiescoreEMR middleware partner providing device driver interface to enable SmartGuard pupillometry data upload into hospital EMR systems.
- iSirona/NanthealthcoreEMR middleware partner providing device driver interface to enable SmartGuard pupillometry data upload into hospital EMR systems.
- CernercoreEMR middleware partner providing device driver interface to enable SmartGuard pupillometry data upload into hospital EMR systems.
Scale indicators1 record
Recent moves7 records
Expansion highlights6 records
NeurOptics competitors and assessment
Company assessmentDirect peers
- Natus Medical: Natus is a long-standing neurological and neurocritical care monitoring company whose product range (EEG, ICU brain monitoring, neurodiagnostics) overlaps directly with NeurOptics' neurological assessment focus and shares the same hospital neurology customer base.
- Compumedics: Compumedics specializes in neurological diagnostic equipment (EEG, sleep, long-term monitoring) and overlaps with NeurOptics in hospitals and research institutions performing quantitative neurological assessments.
- iCare (Revenio Group): iCare manufactures handheld ophthalmic diagnostic devices (tonometers, retinal imaging) used in ophthalmology and optometry practices — comparable to NeurOptics' VIP-400 and PLR-4000 research/clinical devices in target customers and handheld optical form factor.
Broad incumbents
- Masimo: Masimo is a leading patient-monitoring company with growing neurological monitoring offerings and deep ICU/hospital relationships; its broader portfolio and R&D scale make it both a partner and a potential competitive threat to NeurOptics in quantitative neuro assessment.
- Integra LifeSciences: Integra has a significant neurosurgery and neurocritical care portfolio (including ICP monitoring and tissue oxygenation), serving the same neuro ICU customers as NeurOptics and providing an adjacent platform for pupillometry bundling or competition.
- Nihon Kohden: Nihon Kohden is a global patient-monitoring and neurology company (EEG, polysomnography, ICU monitors) that sells into the same neurocritical care and emergency department purchasing channels as NeurOptics.
- Welch Allyn (Baxter International): Welch Allyn (now part of Baxter) manufactures handheld physical-assessment and ophthalmic instruments used by frontline clinicians; it competes with NeurOptics' handheld point-of-care design philosophy and shares many clinical decision-making customers.
Emerging players
- Nonin Medical: Nonin is a specialty patient-monitoring company (pulse oximetry, regional oximetry) selling into hospital and critical-care channels; it represents an adjacent neurological/physiological monitoring peer that could expand into pupillometry.
- Topcon Healthcare: Topcon offers ophthalmic diagnostic and refractive-surgery devices, including pupil measurement tools for LASIK/IOL planning — directly comparable to NeurOptics' VIP-400 product line in ophthalmic applied research.
Others
- Capsule Technologies (Mindray): Capsule Technologies is an EMR medical-device integration platform and current NeurOptics partner for SmartGuard data upload; it is a key enabling technology vendor rather than a competitor, but its broader ICU integration footprint is strategically relevant.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
NeurOptics social profiles
Digital presenceNeurOptics compliance and trust
Trust signalCompliance3 records
NeurOptics financial estimates
Financial estimateRevenue estimate
Valuation estimate
NeurOptics leadership team
Management profileNumber of profiles
Profiles2 records
NeurOptics funding detail
Funding detailFunding overview
Funding rounds3 records
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
NeurOptics M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about NeurOptics
What does NeurOptics do?
NeurOptics manufactures and sells automated infrared pupillometers that objectively measure pupil size and reactivity in critical care and emergency settings, scoring results on its proprietary Neurological Pupil index (NPi) scale. Its core commercial offering centers on the NPi-300 and NPi-200 handheld pupillometers, supported by single-patient-use SmartGuard disposables and the NPi-Connect EMR connectivity hub, with separate research-grade devices (VIP-400, PLR-4000) sold for ophthalmic and pharmaceutical research applications.
Is NeurOptics a public or private company?
NeurOptics is a private company. It is classified as venture growth investor backed and is currently operating.
When was NeurOptics founded?
NeurOptics was founded in 1995. It employs 1 to 10 people.
Where is NeurOptics based?
NeurOptics is headquartered in Laguna Hills, United States, in the North America region.
How does NeurOptics make money?
Three revenue lines are on record. Hardware Sales (Pupillometers) is the primary driver. The others are disposable SmartGuard and applied Research Products.
Who are NeurOptics's main competitors?
Direct peers on record are Natus Medical, Compumedics and iCare (Revenio Group). Broad incumbents are Masimo, Integra LifeSciences, Nihon Kohden and Welch Allyn (Baxter International). Emerging players are Nonin Medical and Topcon Healthcare. Capsule Technologies (Mindray) is listed as an others.
Does NeurOptics have an API?
No public API is recorded for NeurOptics.
What industry is NeurOptics in?
NeurOptics's product category is Medical Pupillometry Devices. Its primary akta.pro industry code is HLAHACAE, Neurological Monitoring (EEG, Seizure/Sleep/Neuro Wearables), with a secondary code of HLAHAJAC, Visual Field & Functional Vision Testing (Perimetry, ERG/VEP, Contrast Sensitivity). Its NAICS code is 334510 and its SIC code is 3845.