baseclick
baseclick GmbH is a Munich-based specialty manufacturer of click chemistry reagents, IVT and ClickSeq NGS kits, and custom oligo/mRNA services used by academic researchers, pharmaceutical developers, and diagnostic companies working on nucleic acid therapeutics and analysis.
- Company typePrivate
- Founded2008
- HeadquartersNeuried, Germany
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What baseclick does
baseclick GmbH is a privately-held German biotechnology company founded in 2008 and headquartered in Neuried (Munich), that develops and manufactures click-chemistry-based reagents, kits, and services for nucleic acid research and mRNA therapeutics manufacturing. Its core technology is centered on CuAAC (copper-catalyzed) and SPAAC (copper-free, DBCO-based) azide-alkyne cycloaddition chemistries, applied across four product pillars: (1) baseScribe IVT kits for mRNA synthesis with GMP-grade enzymes, CleanCap co-transcriptional capping, and modified nucleotide (pseudouridine, N1-methylpseudo-UTP) support yielding 140–180 µg mRNA per reaction; (2) ClickSeq NGS library preparation kits (DNA, RNA, Poly(A), X-ClickSeq, Long-Read) that use click chemistry to eliminate enzymatic fragmentation and ligation bias; (3) EdU-based cell proliferation assays for imaging, flow cytometry, and high-throughput screening; and (4) a broad catalog of bioconjugation reagents (DBCO linkers, NHS-azides, modified nucleotides, nucleosides, phosphoramidites, and cell-targeting ligands such as Tri-GalNAc and Tri-Mannose).
The company monetizes through three revenue streams: one-time catalog sales of research reagents and kits via its baseclick.eu e-commerce storefront; custom oligonucleotide synthesis and conjugation services delivered jointly with metabion AG (announced March 2026); and an mRNA production service delivered jointly with Eurofins Genomics. Distribution is handled through a global network of more than ten partners including Thermo Fisher Scientific, Roche, Merck, Abcam, BD, Carl Roth, Zageno, Tebubio, Jena Bioscience, Lucerna Chem, and the US-focused Labscoop marketplace. Its customer base spans academic and institutional life science researchers, pharmaceutical developers of modified oligos and mRNA therapeutics, and diagnostic developers of nucleic acid assays. Manufacturing is performed in-house in Germany under ISO 9001:2015 certification, and baseclick maintains a wholly-owned vaccine subsidiary (baseclick Vaccine GmbH, established 2021) for coronavirus vaccine work that is operated separately from the core reagents business.
baseclick firmographics
Firmographics- Name
- baseclick
- Legal name
- baseclick GmbH
- Website
- https://baseclick.eu
- Company type
- Private
- Founded year
- 2008
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- baseclick GmbH is a Munich-based specialty manufacturer of click chemistry reagents, IVT and ClickSeq NGS kits, and custom oligo/mRNA services used by academic researchers, pharmaceutical developers, and diagnostic companies working on nucleic acid therapeutics and analysis.
- Ownership category
- akta.pro rank
baseclick industry classification
Industry- Product category
- Life Science Research Reagents
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714), In-Vitro Diagnostic Substance Manufacturing (325413)
- SIC
- Services-Commercial Physical & Biological Research (8731), In Vitro & In Vivo Diagnostic Substances (2835)
- akta.pro primary industry
- mRNA & Nucleic Acid Manufacturing Services (mRNA/saRNA/Plasmid DNA) (HLAGAGAC)
- akta.pro secondary industries
- RNA Manufacturing & CMC (oligo synthesis, IVT, purification, formulation, QC) (HLAAADAF), Genomics & Next-Generation Sequencing (NGS) Services (HLAGANAA)
Keywords
Where baseclick is headquartered
LocationHeadquarters
- HQ city
- Neuried
- HQ country
- Germany
- HQ region
- Europe
Offices1 record
Markets served
baseclick business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Supply Chain, Operations, Technology or R&D, Marketing or Sales, Infrastructure
Revenue model
- Research Reagents and Kits: Sale of click chemistry reagents, IVT kits, NGS library prep kits, nucleotides, fluorescent dyes, and bioconjugation reagents through e-commerce platform and distribution network.
- Custom Oligonucleotide Synthesis and Conjugation Services: Integrated oligo synthesis through metabion partnership combined with baseclick's conjugation services for custom functionalized oligos, mRNA synthesis, and modification.
- mRNA Synthesis Services: Ready-to-use modified mRNA production through Eurofins partnership including plasmid DNA production, IVT synthesis, capping, poly(A) tailing, internal modifications, and click conjugation.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Pay-as-you-go | Standard research reagents |
| Unit Pricing | Pay-as-you-go | IVT and NGS kits |
| Other | Pay-as-you-go | Custom services |
Go-to-market motion2 records
Distribution channels4 records
Marketing channels5 records
baseclick product offering
Product offeringCore offering
baseclick manufactures and sells click chemistry reagents, NGS library preparation kits, and in vitro transcription (IVT) mRNA synthesis kits used by life science researchers to modify, label, and analyze nucleic acids. The company also provides custom oligonucleotide synthesis and conjugation services together with metabion, and mRNA production services in collaboration with Eurofins Genomics, sold primarily through its e-commerce website and global life science distribution partners.
Product overview
baseclick is a German biotech company specializing in click chemistry solutions for nucleic acid research, offering a comprehensive portfolio of reagents, kits, and services. The product portfolio centers on click chemistry-based tools (CuAAC and SPAAC) for nucleic acid labeling, modification, and analysis. Core product lines include: (1) baseScribe IVT kits for mRNA synthesis including standard T7, Cap1, and modified nucleotide variants; (2) ClickSeq library prep kits for NGS (DNA, RNA, Poly(A), X-ClickSeq variants and Long-Read) providing fragmentation-free, ligation-free sequencing; (3) EdU-based cell proliferation assays for imaging, flow cytometry, and HTS; (4) comprehensive click chemistry reagents including DBCO linkers (NHS ester, alkyne, PEG4 variants), NHS-C3-Azide, and fluorescent dyes; (5) modified nucleotides (5-EUTP, pseudouridine, N1-methylpseudo-UTP, 2-EATP, 3'-Azido-ddGTP, 2'-Azido-dATP) for RNA/DNA synthesis and labeling; (6) RNA cap structures (ARCA, CleanCap, functionalized cap analogs); (7) nucleosides (EdU, EU, EdC) and DNA nucleotides; (8) targeting reagents (Tri-GalNAc, mannose conjugates); (9) protein modification reagents (6-Azido-L-lysine); and (10) services including custom oligo synthesis/conjugation (with metabion) and mRNA synthesis (with Eurofins). The company operates from Munich, Germany since 2008 with ISO 9001:2015 certification.
Differentiator
Problem solved
Functional benefit
Products and services
- baseScribe IVT T7 RNA Synthesis Kit A ready-to-use T7 RNA polymerase system for in vitro transcription yielding 140–180 µg mRNA per reaction with GMP-grade enzymes and compatibility with click-modified nucleotides. For researchers producing mRNA for therapeutics and RNA-based studies.
- baseScribe Cap1 IVT Kit In vitro transcription kit for co-transcriptional capping with CleanCap or ARCA, producing capped mRNA with superior translation properties. For researchers synthesizing capped mRNA.
- baseScribe Mod Cap1 IVT Kit Kit for synthesizing immunosilent, capped mRNA incorporating modified nucleotides (pseudouridine or N1-methylpseudouridine) with high yield and reduced immunogenicity. For mRNA therapeutic developers.
- DNA-ClickSeq Library Prep Kit Fragmentation-free, ligation-free Illumina library prep kit using click chemistry for DNA sequencing, available in single and dual indexing variants. For sequencing core facilities and genomics labs.
- RNA-ClickSeq Library Prep Kit Fragmentation-free, ligation-free NGS library preparation kit for Illumina platforms for RNA sequencing, available in single and dual indexing variants. For transcriptomics researchers.
- Poly(A)-ClickSeq Library Prep Kit Selective 3'-end mRNA sequencing kit using click chemistry for Illumina platforms, enabling targeted transcript analysis. For gene expression profiling laboratories.
- X-ClickSeq Library Prep Kit Custom-primer, fragmentation-free NGS library preparation kit compatible with user-provided primers in reverse-transcription reaction. For RNA-seq workflows with custom priming strategies.
- ClickTech Long-Read Library Prep Kit Library prep kit for long-read third-generation sequencing using click chemistry for full-length reverse transcript amplification. For long-read sequencing facilities.
- EdU Cell Proliferation Kit EdU-based cell proliferation assay for reliable measurement of DNA synthesis with clear readout and robust reagents, available for imaging, flow cytometry, and high-throughput screening. For cell biology and immunology labs.
- Click Chemistry Reagents (CuAAC and SPAAC portfolio) Comprehensive portfolio of click chemistry reagents including CuAAC and SPAAC reagents (DBCO linkers, azido handles, NHS ester crosslinkers) for bioconjugation of nucleic acids and proteins. For bioconjugation researchers.
- Cell Targeting Ligands Targeting reagents including Tri-GalNAc, Tri-Mannose, Mannose-6-phosphate, and Lewis antigens for receptor-mediated cellular uptake of oligonucleotides. For oligonucleotide therapeutics developers.
- mRNA Synthesis Service Custom mRNA production service offering stabilization, immunomodulation, cell type-specific targeting concepts, and IVT mRNA production, delivered in partnership with Eurofins Genomics. For therapeutic mRNA developers.
- Custom Oligonucleotide Synthesis & Conjugation Service Integrated service combining metabion's high-precision oligonucleotide synthesis (DNA, RNA, LNA, siRNA from research to GMP-grade) with baseclick's site-specific click chemistry conjugation (5', 3', and internal modifications including targeting ligands) to deliver custom functionalized oligos. For pharmaceutical and diagnostic developers.
Quantifiable outcome
- Up to 180 µg mRNA yield per 20 µL IVT reaction
- +3 more outcomes
Companies that use baseclick
Customer profileNamed customers1 record
Segments3 records
Ideal customer profiles3 records
baseclick technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature5 records
baseclick partnerships and signals
Strategic signalPartnerships
13 partnerships are on record, tiered core, major and regional.
- metabion AGcoreCollaboration between baseclick GmbH and metabion AG provides researchers with integrated oligonucleotide synthesis and conjugation services. metabion handles high-precision oligo manufacturing (DNA, RNA, LNA, siRNA) from research to GMP-grade, while baseclick provides site-specific conjugation using CuAAC and SPAAC click chemistry. The partnership enables targeted and functionalized oligos in one step.
- Labscoop MarketplacecoreLong-term distribution agreement marking baseclick's entry into the US marketplace. Labscoop provides marketplace platform access for US customers to purchase baseclick's nucleic acid bioconjugation and labeling products.
- Thermo Fisher ScientificmajorDistribution partner making baseclick products available through Thermo Fisher Scientific's global sales network.
- RochemajorDistribution partner for baseclick click chemistry and nucleic acid research products.
- MerckmajorDistribution partner (through Sigma-Aldrich brand) for baseclick products.
- AbcammajorDistribution partner for baseclick products.
- Carl RothcoreEuropean distribution partner for baseclick products.
- ZagenocoreSpecialty distribution partner for baseclick products through Zageno's research product marketplace.
- TebubiocoreStrategic partnership announced March 2024 to revolutionize nucleic acid bioconjugation and labeling, providing researchers with cutting-edge access.
- BD (Becton Dickinson)majorDistribution partner for baseclick products.
- Lucerna ChemregionalRegional distribution partner (Switzerland) for baseclick products.
- Jena BioscienceregionalRegional distribution partner for baseclick products.
- Eurofins GenomicscoreJoint mRNA service partnership where Eurofins provides plasmid DNA production and baseclick provides high-yield IVT mRNA synthesis, capping, poly(A) tailing, internal modifications (N1-methylpseudouridine, 5-ethynyl uridine), site-specific click conjugation, and quality control.
Scale indicators2 records
Recent moves6 records
Expansion highlights5 records
baseclick competitors and assessment
Company assessmentDirect peers
- Metabion International: Metabion is an oligonucleotide synthesis specialist offering DNA, RNA, LNA, and siRNA with GMP capabilities. Although now a strategic partner of baseclick, it is a direct peer in custom oligo manufacturing and a competitor in nucleic acid production services.
- Lumiprobe Corporation: Lumiprobe manufactures fluorescent dyes and click chemistry reagents (DBCO, azide, alkyne) for bioconjugation and nucleic acid labeling, closely mirroring baseclick's reagent and dye product categories.
- Eurogentec (Kaneka): Eurogentec offers custom oligonucleotide synthesis, modified nucleotides, and bioconjugation services, overlapping with baseclick's custom oligo and conjugation product lines.
- Click Chemistry Tools: Click Chemistry Tools specializes in azide-alkyne cycloaddition reagents, bioconjugation linkers (DBCO, BCN), and click-enabled probes — a near-direct match for baseclick's CuAAC and SPAAC reagent lines.
- TriLink BioTechnologies (Maravai LifeSciences): TriLink is a leading manufacturer of modified nucleotides (pseudouridine, N1-methylpseudo-UTP), IVT reagents, and mRNA synthesis services, directly comparable to baseclick's baseScribe IVT kit and mRNA service offering.
- Biosearch Technologies (LGC Group): Biosearch Technologies provides custom oligonucleotide synthesis, fluorescent probes, and nucleic acid labeling reagents, serving the same research and diagnostic customer base as baseclick.
- Jena Bioscience: Jena Bioscience develops and sells modified nucleotides, click chemistry reagents, and nucleic acid labeling tools, directly overlapping with baseclick's core product portfolio. Although Jena Bioscience is also a distribution partner, it operates as a comparable competitor in the same product categories.
- ChemGenes Corporation: ChemGenes manufactures phosphoramidites, modified nucleosides, and oligonucleotide synthesis reagents, directly relevant to baseclick's phosphoramidite and modified nucleotide offerings.
Emerging players
- Vector Laboratories: Vector Laboratories (parent of Click Chemistry Tools) focuses on bioconjugation reagents, protein labeling kits, and detection systems. It overlaps with baseclick's DBCO and azide reagent lines and competes in bioconjugation workflows.
Broad incumbents
- Bio-Techne: Bio-Techne is a broad life science reagent incumbent with extensive nucleic acid, protein, and cell biology product lines. It is a much larger competitor that serves many of the same academic and pharmaceutical research customers as baseclick.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat5 records
Key risks5 records
Key highlights7 records
Customer concentration
baseclick social profiles
Digital presencebaseclick compliance and trust
Trust signalCompliance2 records
baseclick financial estimates
Financial estimateRevenue estimate
Valuation estimate
baseclick leadership team
Management profileNumber of profiles
Profiles2 records
baseclick subsidiaries and ownership
Company hierarchySubsidiaries1 record
baseclick funding detail
Funding detailFunding overview
Funding rounds1 record
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
baseclick M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about baseclick
What does baseclick do?
baseclick manufactures and sells click chemistry reagents, NGS library preparation kits, and in vitro transcription (IVT) mRNA synthesis kits used by life science researchers to modify, label, and analyze nucleic acids. The company also provides custom oligonucleotide synthesis and conjugation services together with metabion, and mRNA production services in collaboration with Eurofins Genomics, sold primarily through its e-commerce website and global life science distribution partners.
Is baseclick a public or private company?
baseclick is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was baseclick founded?
baseclick was founded in 2008. It employs 11 to 50 people.
Where is baseclick based?
baseclick is headquartered in Neuried, Germany, in the Europe region.
How does baseclick make money?
Three revenue lines are on record. Research Reagents and Kits are the primary driver. The others are custom Oligonucleotide Synthesis and Conjugation Services and mRNA Synthesis Services.
Who are baseclick's main competitors?
Direct peers on record are Metabion International, Lumiprobe Corporation, Eurogentec (Kaneka), Click Chemistry Tools, TriLink BioTechnologies (Maravai LifeSciences), Biosearch Technologies (LGC Group), Jena Bioscience and ChemGenes Corporation. Vector Laboratories is listed as an emerging player. Bio-Techne is listed as a broad incumbent.
Does baseclick have an API?
No public API is recorded for baseclick.
What industry is baseclick in?
baseclick's product category is Life Science Research Reagents. Its primary akta.pro industry code is HLAGAGAC, mRNA & Nucleic Acid Manufacturing Services (mRNA/saRNA/Plasmid DNA), with a secondary code of HLAAADAF, RNA Manufacturing & CMC (oligo synthesis, IVT, purification, formulation, QC). Its NAICS code is 541714 and its SIC code is 8731.