Holtorf Medical Group

What Holtorf Medical Group does

Holtorf Medical Group is a private, for-profit integrative and functional medicine practice headquartered in El Segundo, California, founded by Dr. Kent Holtorf. The practice treats complex, chronic, and often multi-system conditions that have not responded to conventional care, including Lyme disease and tick-borne illness, Chronic Fatigue Syndrome, fibromyalgia, thyroid dysfunction, hormonal imbalances, CIRS, MCAS, long-COVID, autoimmune disorders, and neurodegenerative disease. Patients typically present after seeing an average of 7.2 other physicians without improvement, positioning Holtorf as a tertiary referral point for difficult cases.

The clinical offering is built around a proprietary protocol called the Holtorf Way, which combines conventional medications, customized compounded drugs, vitamin and mineral supplements, hormone replacement, and innovative modalities such as EBOO (Extracorporeal Blood Oxygenation and Ozonation), Low Dose Immunotherapy (LDI/LDA), Low Dose Naltrexone (LDN), peptide and bioregulator therapy, PEMF, Prolozone, IV nutrient therapy, and Bioidentical Hormone Replacement Therapy (BHRT). Diagnostic services include proprietary Thyroid Trio Testing (BMR, Thyroflex reflex, and iodine deficiency assessment), and a published 500-patient study in the Journal of Chronic Fatigue Syndrome reports 94% improvement by the 4th visit.

The business model is direct-to-consumer and largely cash-pay: patients book online or by phone, pay a $100 non-refundable deposit for the first appointment, and settle at time of service, with lab work, prescriptions, IV treatments, and some visits potentially reimbursable through out-of-network PPO claims. Distribution extends beyond the El Segundo flagship via 23 corporately owned affiliate centers and 12 franchises, plus Telehealth Services on Zoom and a wholly-owned supplement e-commerce brand, Holtraceuticals. Five providers are listed on the website (Kent Holtorf MD, Nancy Evans ND, Moses Laufer MD, Wayne D. Wightman MD, Barbara Rush ND), supported by a total headcount of 11-50 employees.

Name

Holtorf Medical Group

Legal name

Holtorf Medical Group

Website

https://holtorfmed.com

Company type

Private

Founded year

2008

Operating status

Operating

Headcount range

11–50 employees

Short description

Holtorf Medical Group is a private, cash-pay integrative and functional medicine practice in El Segundo, California that treats complex chronic conditions such as Lyme disease, chronic fatigue syndrome, fibromyalgia, and hormonal imbalances using the proprietary Holtorf Way Protocol, operating 23 affiliate centers and 12 franchises with a supplemental Holtraceuticals product line.

Ownership category

akta.pro rank

Product category

Integrative and Functional Medicine Practice

NAICS

Medical and Diagnostic Laboratories (62151)

SIC

Services-Offices & Clinics Of Doctors Of Medicine (8011)

akta.pro primary industry

Thyroid Disorders (HLAKADAF)

Keywords

• Integrative medicine services
• Functional medicine practice
• Bioidentical hormone therapy
• Chronic fatigue treatment
• Lyme disease treatment

Headquarters

HQ city

El Segundo

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Supply Chain, Technology or R&D

Revenue model

1. Medical Consultation and Treatment Services: Revenue generated from office visits, diagnostic testing, IV therapies, hormone replacement treatments, and specialized therapies like EBOO, PEMF, Low Dose Immunotherapy. Patients pay at time of service with $100 non-refundable deposit required for first appointment.
2. Holtraceuticals Supplement Line: Proprietary pharmaceutical-grade supplement line developed by Dr. Holtorf, sold through holtraceuticals.com. Refund policy: unopened supplements refunded within 30 days.
3. Insurance Reimbursement: Lab work, prescriptions, IV treatments, and office visits may be partially covered by insurance. Practice is out-of-network provider, patients submit claims to PPO insurance for possible reimbursement.

Pricing tiers

Go-to-market motion1 record

Distribution channels5 records

Marketing channels8 records

Core offering

Holtorf Medical Group operates an integrative and functional medicine practice delivering personalized diagnostic and treatment services for complex chronic conditions such as Lyme disease, Chronic Fatigue Syndrome, Fibromyalgia, thyroid disorders, and hormonal imbalances. Treatment combines conventional medications, customized compounded drugs, vitamin/mineral supplements, and innovative therapies including bioidentical hormone replacement, peptide therapy, EBOO, IV therapy, Low Dose Immunotherapy, Red Light Therapy, and PEMF, unified by comprehensive diagnostic testing (including proprietary Thyroid Trio). The practice is led by Dr. Kent Holtorf and supported by a subsidiary supplement brand, Holtraceuticals.

Product overview

Holtorf Medical Group operates as an integrative and functional medicine practice offering a coordinated suite of treatments organized around core therapeutic modalities. The portfolio centers on IV Therapy (including EBOO), Bioidentical Hormone Replacement Therapy, and Peptide/Bioregulator Therapies as primary offerings, complemented by diagnostic services (Comprehensive Testing including Thyroid Trio), Low Dose Immunotherapy/Allergen/Naltrexone protocols, Red Light Therapy, PEMF, and Prolozone Therapy. The group also offers a Holtraceuticals-branded supplement line sold through a separate e-commerce site, Telehealth Services for virtual care, and a Veterans Appreciation Program. The approach is integrative, combining conventional medications, customized compounded drugs, vitamin and mineral supplements, and innovative therapies, unified by comprehensive diagnostic testing to create personalized treatment plans.

Differentiator

Problem solved

Functional benefit

Brands

• Holtraceuticals: Doctor-formulated pharmaceutical grade nutritional supplements developed by Dr. Kent Holtorf, sold through holtraceuticals.com

Products and services

• IV Therapy
• EBOO Therapy
• Red Light Therapy
• Bioidentical Hormone Replacement Therapy (BHRT)
• Comprehensive Testing
• Peptide and Bioregulator Therapies
• Low Dose Immunotherapy (LDI)
• Low Dose Allergen (LDA)
• Low Dose Naltrexone (LDN)
• Pulsed Electro-Magnetic Frequency (PEMF)
• Prolozone Therapy
• Holtraceuticals Supplements
• Telehealth Services
• Veterans Appreciation Program

Quantifiable outcome

• 94% of patients had overall improvement by the 4th visit
• +5 more outcomes

Named customers5 records

Segments6 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration2 records

Feature6 records

Partnerships

One partnership is on record.

• Regional Health System and Academic Medical Center PartnerscoreStrategic or Co-development PartnerHoltorf Medical Group has partnered with select health systems and academic medical centers in some markets to provide Medical Services, with the exception of Telehealth Services. These Partner relationships are described in the Terms of Service and allow for the provision of medical services in identified regions through subcontracting arrangements.

Scale indicators6 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• BodyLogicMD: National network of physicians specializing in bioidentical hormone replacement therapy, integrative medicine, and wellness optimization. Comparable franchise/network model with multi-provider clinics focused on hormone, thyroid, and anti-aging medicine — overlapping patient base and treatment philosophy with Holtorf.
• Cenegenics: Age management and performance medicine franchise operating a network of physician-led clinics focused on hormone optimization, longevity, and preventive care. Direct comparator on cash-pay integrative/anti-aging model and franchise scaling strategy.
• Parsley Health: Membership-based functional medicine practice combining conventional and integrative care with longer appointments and root-cause diagnostics. Direct DTC peer on functional medicine model with chronic-condition focus, though operates via telehealth + in-person hybrid.
• Mark Hyman / The UltraWellness Center: Functional medicine practice founded by Dr. Mark Hyman focused on chronic illness, nutrition, and lifestyle medicine. Comparable on founder-driven brand, functional/integrative protocols, and chronic-disease patient base.
• Amen Clinics: Multi-clinic brain health practice using SPECT imaging and integrative protocols for conditions including TBI, PTSD, ADHD, and depression. Comparable on multi-clinic brain/mental health treatment focus overlapping with Holtorf's neurological/mental health and veterans segments.
• SottoPelle / BioTE Medical: National provider network specializing in bioidentical hormone replacement via pellet therapy. Comparable on BHRT service line and provider-network/franchise model, with significant overlap in hormone-optimization patient segment.

Broad incumbents

• IFM (The Institute for Functional Medicine): Leading educational and certification body for functional medicine practitioners globally. Comparable space through shared functional medicine philosophy, though IFM is a training/certification body rather than a clinical operator — it shapes the practitioner universe Holtorf recruits from.
• Cleveland Clinic Center for Functional Medicine: Hospital-affiliated functional medicine program within a major academic medical center. Represents the institutional/incumbent version of functional medicine, validating the category and competing for the same patient demographic.

Others

• Holtraceuticals (subsidiary): Doctor-formulated nutritional supplement brand owned by Holtorf Medical Group. Listed for completeness — internal e-commerce arm that monetizes patient relationships beyond clinic visits.

Regional players

• Restore Hyper Wellness: Franchise-based wellness clinic chain offering IV therapy, red light therapy, cryotherapy, and hyperbaric oxygen. Comparable on the consumer wellness franchise model and overlap with several Holtorf service lines (IV, red light), though focused on elective wellness rather than chronic illness.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat3 records

Key risks6 records

Key highlights6 records

Customer concentration

• Facebookfacebook.com/holtorfmed
• Instagraminstagram.com/holtorfmedicalgroup

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Holtorf Medical Group