MTHFR Support Australia

What MTHFR Support Australia does

MTHFR Support Australia is a privately held specialty health clinic headquartered in Neutral Bay, Sydney, that operates the world's first dedicated clinic for MTHFR gene mutations and methylation-related health conditions. Founded in 2012 by naturopath and researcher Carolyn Ledowsky, the company focuses on genetic testing and personalised treatment protocols for individuals whose MTHFR gene variants impair folate metabolism and contribute to chronic health issues including fertility problems, recurrent miscarriage, fatigue, anxiety, depression, migraines, and cardiovascular conditions. The reported customer base exceeds 2,000 Australians, with reach extending into the US and UK.

The company's core technology is the SMART DNA Advanced Pathways Test, a buccal swab genetic test that analyses over 300 biochemical SNPs covering methylation, detoxification, neurotransmitter, cardiovascular, inflammatory, histamine, and metabolic pathways. Based on test results, MTHFR Support delivers personalised treatment plans combining active folate supplementation, dietary guidance, and lifestyle protocols, supported by a clinical team of naturopaths and nutritionists. The company also operates complementary product lines: the Patient Knowledge Centre (recurring membership education platform), the Fertility Hub (AUD $499 fertility education membership), and the Functional Genomics Institute (practitioner accreditation and Mastermind mentoring program). Branded supplements (methylfolate, B12 drops, prenatal vitamins) and genetic test kits are sold direct-to-consumer through dedicated e-commerce sites for Australia/New Zealand and the US.

MTHFR Support monetises through a multi-stream model: clinical consultations priced from AUD $80 for 15-minute urgent calls to AUD $610 for 90-minute fertility appointments; bundled service packages (Complete Genetic Health Package AUD $1,166; Complete Fertility Package AUD $1,230); recurring memberships; practitioner training courses including the Mastermind Programme; and consumer product sales. The go-to-market approach is direct-to-consumer via company websites, social channels, and educational content, supplemented by a practitioner referral and affiliate network that distributes protocols across Australia, the US, and the UK. The company is bootstrapped, with no external funding rounds or institutional investors disclosed in the source material.

Name

MTHFR Support Australia

Legal name

MTHFR Support LLC

Website

https://mthfrsupport.com.au

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

11–50 employees

Short description

MTHFR Support Australia is a private specialty clinic in Sydney that provides genetic testing, personalised treatment protocols, and educational memberships for individuals with MTHFR gene mutations. It sells consultations, supplements, and practitioner training across Australia, the US, and the UK.

Ownership category

akta.pro rank

Product category

Specialised Methylation Health Services

NAICS

Medical Laboratories (621511)

SIC

Services-Health Services (8000)

akta.pro primary industry

Medication Therapy Management (MTM) & Clinical Pharmacy Services (HLAFALAH)

akta.pro secondary industry

Pharmacogenomics (PGx) Decision Support (HLAAANAB)

Keywords

• Genetic testing services
• Methylation health clinic
• Naturopathic consultations
• Fertility support services
• Practitioner training programs

Headquarters

HQ city

Neutral Bay

HQ country

Australia

HQ region

Oceania

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Infrastructure

Revenue model

1. Clinical Consultations: Paid consultations with MTHFR-specialised practitioners including initial genetic consultations (75-90 minutes), follow-up appointments, and fertility consultations. Prices range from $80 for urgent 15-minute calls to $610 for 90-minute fertility appointments.
2. Genetic Testing Products: Sale of SMART DNA genetic test kits and MTHFR-specific test kits directly to consumers and through practitioner channels.
3. Supplements: Sale of MTHFR-specific supplements including prenatal vitamins, methylfolate, B12 drops, and related health products through their online store.
4. Membership Subscriptions: Patient Knowledge Centre annual membership providing access to webinars, resources, and community access. Also offers practitioner memberships through the Functional Genomics Institute.
5. Package Deals: Bundled service packages combining genetic testing with consultations at discounted rates. Complete Genetic Health Package at $1,166 AUD and Complete Fertility Package at $1,230 AUD.
6. Fertility Hub: One-time purchase of $499 for unlimited access to fertility education hub with webinars, resources, and treatment roadmaps.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels7 records

Core offering

MTHFR Support Australia operates a specialised clinic that provides genetic testing for MTHFR gene polymorphisms and related SNPs, delivers personalised treatment protocols using active folate forms, and offers one-on-one clinical consultations with naturopaths and nutritionists. The company also sells related supplements, test kits, and educational courses/memberships to both patients seeking methylation-related health support and healthcare practitioners seeking training in functional genomics.

Product overview

MTHFR Support Australia operates as a multi-service health clinic specializing in MTHFR gene mutations and methylation-related health conditions. The company offers a portfolio of genetic testing products (SmartDNA with 300+ SNPs, MTHFR Buccal Swab Test Kit), educational membership platforms (Patient Knowledge Centre, Methylation and Genomics Institute, Fertility Hub), practitioner training programs (Mastermind Programme, Mastermind PLUS, MTHFR and Methylation in Clinical Practice Course), bundled service packages (Complete Genetic Health Package, Complete Fertility Genetic Package), histamine relief product bundles, and direct clinical consultation services. The core offering centers on personalized genetic-based health assessment and guidance, with educational resources and practitioner training serving as complementary revenue streams.

Differentiator

Problem solved

Functional benefit

Brands

• MTHFR Fertility Hub: Comprehensive fertility education resource centre with webinars, ebooks, and courses for couples struggling with fertility
• Patient Knowledge Centre (PKC)
• The Methylation and Genomics Institute
• Functional Genomics Institute

Products and services

• SmartDNA Advanced Pathways Genetic Test Genetic testing service analysing DNA for methylation-related gene variations including MTHFR C677T and A1298C polymorphisms, plus over 300 biochemical SNPs covering detoxification, neurotransmitter, fat metabolism, energy production, inflammation and other genomic pathways. Sold direct-to-consumer and through practitioner channels.
• MTHFR Support Clinic Consultations One-on-one clinical consultations with MTHFR-specialised naturopaths and nutritionists covering initial assessment, follow-up appointments and specialised 90-minute fertility consultations.
• MTHFR Buccal Swab Test Kit At-home genetic testing kit using buccal swab sample collection to identify MTHFR gene polymorphisms (C677T, A1298C), providing easy-to-understand results.
• Patient Knowledge Centre (PKC) Annual online learning membership for patients providing access to webinars, monthly live Q&A sessions with Carolyn Ledowsky, free resources, latest research and a private Facebook community, with a 10% discount on supplements.
• Fertility Hub Subscription resource centre for couples experiencing fertility challenges, providing webinars, eBooks, checklists and treatment roadmaps covering egg and sperm quality, folate, estrogen metabolism, thyroid, histamine, age-related infertility, fertility testing, genetic SNPs and treatment strategies.
• Functional Genomics Institute (Methylation and Genomics Institute) Accreditation program for healthcare practitioners delivering hundreds of hours of presentations, webinars, video content, case studies, monthly live educational sessions, SNP series, handouts and downloads, with access to a practitioner-only Facebook group.
• Mastermind Programme 7-week intensive guided learning course for practitioners covering clinical implications of genetic susceptibility, including a goal-setting call and positioning as a revenue-generating clinical investment.
• Mastermind PLUS Advanced 1:1 mentoring for Mastermind graduates featuring fortnightly group online meetings for patient case reviews, practical case presentations evaluated by Carolyn Ledowsky, and ongoing professional development.
• MTHFR and Methylation in Clinical Practice Course Step-by-step clinical protocols course for health practitioners on addressing methylation issues with patients, covering genetic variation complexities and support strategies.
• Complete Genetic Health Package Bundled health assessment package combining the SmartDNA Genetic Test V2, a 75-minute initial practitioner appointment, a 6-month PKC membership, the MTHFR Basic Course, a 15-minute clinic manager appointment, a 10% supplement discount and access to the private Patient Facebook Community.
• Complete Fertility Genetic Package Bundled fertility assessment package combining the SmartDNA Genetic Test V2, a 90-minute fertility consultant appointment, a 3-month Fertility Hub membership, a 15-minute practitioner matching appointment, dedicated Facebook community access and the Guide to PreNatals eBook.
• Histamine Relief Package 1 Education bundle for histamine-related issues, including an understanding histamine guide, a histamine recipe book with 80+ low-histamine recipes and access to the Reducing the Allergy Load webinar.
• Histamine Relief Package 2 Comprehensive histamine support bundle including a histamine-friendly probiotic blend, natural antihistamine supplement, digestive support supplement, histamine recipe book and access to the Reducing the Allergy Load webinar.
• Histamine Relief Package 3 (Complete Histamine Genetics Package) Full-service histamine assessment including an initial consultation with a headaches/migraines/allergies practitioner, the Smart DNA genetic test, the recipe book and webinar access.
• Your Baby Course 12-week preconception program by Carolyn Ledowsky covering genetic analysis, functional testing interpretation, and emotional support through Facebook groups and private sessions, designed to help couples identify genetic susceptibilities and optimal folate requirements.
• MTHFR-Specific Supplements Range of MTHFR-specific nutritional supplements sold through the company's own e-commerce stores, including prenatal vitamins, methylfolate, B12 drops and related products.

Quantifiable outcome

• 91%+ clinical success rate in fertility patients with MTHFR mutations, multiple miscarriage history, and/or failed IVF who received appropriate methyl folate protocols
• +2 more outcomes

Named customers5 records

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators5 records

Recent moves6 records

Expansion highlights6 records

Others

• XYMOGEN: Practitioner-exclusive nutraceutical brand offering methylated folate and methylation-support formulations; adjacent peer that competes for the same practitioner-channel supplement dollars that fund MTHFR Support's referral ecosystem.

Emerging players

• Color Genomics: Clinical-grade genetic testing company with hereditary cancer, pharmacogenomics, and population health offerings; competes for the same at-home DNA testing and clinical-decision-support budgets as MTHFR Support's SmartDNA.
• Viome: At-home microbiome and mRNA-based testing platform selling personalized supplements and recommendations; overlaps with MTHFR Support's at-home genetic/microbiome testing plus tailored supplement protocols (e.g., MTHFR Support's SmartGUT test).
• InsideTracker: Personalized health platform combining blood biomarkers, DNA, and lifestyle data into actionable recommendations; comparable in its DTC, biomarker- and genetics-driven personalization model targeting proactive health consumers.
• Genomind: Pharmacogenomic testing company providing genetic insights to guide medication and mental-health treatment decisions, including methylation-related genes; comparable as a clinical-grade genetic decision-support service targeting practitioners.

Direct peers

• Seeking Health: Founded by Dr. Ben Lynch, Seeking Health is the most direct MTHFR-focused peer, offering MTHFR/genetic-based supplements, practitioner resources, and methylation education content targeting the same patient and practitioner audience as MTHFR Support Australia.

Broad incumbents

• Thorne: Premium supplement brand with practitioner channel and at-home health testing (including genetic-based wellness), overlapping with MTHFR Support's supplement and practitioner-training motion but across a much broader wellness portfolio.
• Pure Encapsulations: Practitioner-grade supplement brand focused on purity and clinical formulations, including methylfolate and B-complex products; directly competes in the practitioner-channel methylated-B vitamin and supplement categories central to MTHFR Support's offering.
• Designs for Health: Practitioner-channel supplement and education company offering professional-grade nutraceuticals and clinical protocols; comparable to MTHFR Support in targeting healthcare practitioners with supplements and continuing education.
• 23andMe: Leading direct-to-consumer genetic testing platform offering MTHFR and broader health-related SNP reports; competes for the same customer attention and DTC genetic testing spend but at vastly larger scale and with a much broader genetic panel.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/channel/UCwH3F_dC_uYK36IRvm0iK1Q
• Facebookfacebook.com/mthfrsupportglobal
• LinkedInlinkedin.com/company/mthfr-support-australia
• Instagraminstagram.com/mthfrsupportglobal

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about MTHFR Support Australia