SottoPelle

What SottoPelle does

SottoPelle® is a Scottsdale, Arizona-based bio-identical hormone replacement therapy (BHRT) company operating a B2B2C model centered on a proprietary subcutaneous hormone pellet delivery system. Founded by the late Dr. Gino Tutera (a board-certified OB/GYN who began BHRT practice in 1979 and formally established the company in 2004) and now led by his wife CarolAnn Tutera as President and CEO, the company trains and certifies physicians in the proprietary "SottoPelle Method" via the multi-patented Dosaggio™ dosing calculator, which produces individualized hormone dosing for each patient. Treatments deliver plant-based, molecularly-identical estradiol and/or testosterone via subcutaneous pellets that release consistent 24/7 low-dose hormones over 4-6 months, contrasting with creams, pills, and patches.

The product portfolio spans three core therapy programs — La Bella Vita (women), SottoPelle® Strong (men), and Uniquely You (transgender patients) — plus condition-specific offerings for neurodegenerative diseases (Parkinson's, Alzheimer's, dementia) and traumatic brain injury/sports injuries. Beyond therapy, SottoPelle operates three consumer sub-brands: Caitera (nutraceuticals and professional hair care), Tutti (skincare), and Bolster Beauty by SottoPelle (wellness products), all sold direct-to-consumer via e-commerce. Tutera Medical, a wholly-owned subsidiary run by CarolAnn Tutera, operates four flagship clinic locations in Arizona that demonstrate the SottoPelle Method in clinical practice.

SottoPelle monetizes through multiple revenue streams: multi-year provider training and certification subscriptions, ongoing pellet and medical supply sales to a network of 1,200+ certified providers globally and 3,000+ trained providers in the US, direct-to-consumer e-commerce across Caitera and Tutti, clinical revenue from Tutera Medical's Arizona clinics, and international franchise/licensee operations in Puerto Rico, Spain, Brazil, and Mexico. The company is privately held under two legal entities (SottoPelle®, Inc. and The SottoPelle® Group, LLC) with 11-50 employees, has treated 250,000+ patients over 30+ years, and has received recognition including Arizona's Most Admired Companies (2024, 2025) and a Congressional innovation letter from Rep. David Schweikert.

Name

SottoPelle

Legal name

SottoPelle®, Inc. and The SottoPelle® Group, LLC

Website

https://sottopelletherapy.com

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

11–50 employees

Short description

SottoPelle is a Scottsdale, Arizona-based bio-identical hormone replacement therapy company that trains and certifies physicians in its proprietary pellet delivery method and Dosaggio dosing platform, serving patients across menopause, andropause, transgender, neurodegenerative, and TBI indications via a 1,200+ provider network.

Ownership category

akta.pro rank

Product category

Bio-identical Hormone Replacement Therapy

NAICS

Pharmaceutical Preparation Manufacturing (325412), Toilet Preparation Manufacturing (32562)

SIC

Pharmaceutical Preparations (2834), Perfumes, Cosmetics & Other Toilet Preparations (2844)

akta.pro primary industry

Medication Adherence, Packaging & Fulfillment Services (Blister/Unit-Dose) (HLAFALAJ)

Keywords

• Bioidentical hormone therapy
• Hormone pellet insertion
• Provider training certification
• Menopause andropause treatment
• Wellness supplements skincare

Headquarters

HQ city

Scottsdale

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Supply Chain, Others

Revenue model

1. Provider Training & Certification: SottoPelle trains and certifies physicians and medical practices in pellet therapy methodology. Training includes dosing certification, clinical protocols, and access to the Dosaggio dosing platform. Generates revenue through training program fees and ongoing provider membership subscriptions.
2. Hormone Pellets & Medical Supplies: Provides hormone pellets and related medical supplies to certified providers. Pellets contain bio-identical estradiol and/or testosterone. Revenue generated through product sales to the provider network.
3. Caitera Wellness Products: Consumer nutraceutical and hair care product line sold through caitera.com. Includes hair repair formulas, ADK essentials, DIMM (diindolylmethane), boron supplements, and professional hair care products. Direct-to-consumer e-commerce revenue stream.
4. Tutti Skin Care: Skin care product line sold through tutti.skin. Professional skin care products designed to complement hormone therapy. Direct-to-consumer e-commerce sales.
5. Tutera Medical Clinical Practices: CarolAnn Tutera also operates Tutera Medical with four clinic locations in Arizona serving as flagship demonstration practices for the SottoPelle Method.

Pricing tiers

Go-to-market motion2 records

Distribution channels4 records

Marketing channels8 records

Core offering

SottoPelle provides bio-identical hormone replacement therapy (BHRT) using subcutaneous hormone pellets delivered through its proprietary SottoPelle Method, with the Dosaggio system used to calculate precise patient dosing. The company trains and certifies licensed medical providers who then administer the therapy to patients, while also selling direct-to-consumer supplements and skincare products under its Caitera, Tutti, and Bolster Beauty brands.

Product overview

SottoPelle® is a bioidentical hormone replacement therapy (BHRT) company offering a comprehensive ecosystem of products and services centered on its proprietary pellet delivery system. The core SottoPelle® Method provides personalized hormone pellet therapy that delivers steady, 24/7 hormone dosages for 4-6 months per treatment. The company operates three branded therapy programs: La Bella Vita for women, SottoPelle® Strong for men, and Uniquely You for transgender patients, all utilizing the same pellet technology with individualized dosing through the multi-patented Dosaggio™ calculator. Beyond its core BHRT offerings, SottoPelle® has expanded into adjacent product categories including Caitera (nutraceuticals and professional hair care including Hair Repair Formula, Hair Savior shampoo/conditioner, ADK Essentials, DIMME, and Boron supplements), Tutti (skincare brand), and Bolster Beauty by SottoPelle® (beauty/wellness products). The company also operates a provider training and certification division offering HRT training courses for physicians, maintains a provider directory with 1200+ certified providers, and provides supporting tools including a hormone self-assessment quiz and secure provider login portal. The ecosystem is complemented by educational books authored by founder Dr. Gino Tutera and a wellness podcast series.

Differentiator

Problem solved

Functional benefit

Brands

• Caitera: Doctor-formulated nutraceuticals and professional hair care designed to work in synergy for superior effectiveness and enhanced quality of life.
• Tutti
• Bolster Beauty by SottoPelle
• Dosaggio

Products and services

• SottoPelle Method BHRT Pellet Therapy Proprietary bio-identical hormone replacement therapy (BHRT) delivered via subcutaneous hormone pellets, with dosing calculated using the Dosaggio system; administered through a national network of certified providers to patients.
• La Bella Vita (Women's BHRT) BHRT program tailored to women experiencing menopause, perimenopause, and hormone-related symptoms such as hot flashes, mood changes, low libido, and weight gain; delivered via SottoPelle Method pellet therapy through certified providers.
• SottoPelle Strong (Men's BHRT) BHRT program tailored to men experiencing andropause (low testosterone), fatigue, low libido, mood changes, and muscle loss; delivered via SottoPelle Method pellet therapy through certified providers.
• Uniquely You (Transgender BHRT) BHRT program tailored to transgender individuals seeking hormone optimization as part of their transition care, delivered via SottoPelle Method pellet therapy through certified providers.
• SottoPelle Provider Training & Certification Program Training and certification program that licenses medical providers (MDs, DOs, NPs, PAs) to administer the SottoPelle Method; includes access to the Dosaggio dosing system, the proprietary protocol, and ongoing clinical support.
• Tutera Medical Clinic (Scottsdale, AZ) In-person hormone therapy clinic in Scottsdale, Arizona, where patients receive consultations and SottoPelle Method BHRT pellet insertion therapy directly from affiliated medical providers.
• Caitera Supplements and Hair Care Direct-to-consumer brand offering hormone-support supplements and hair care products targeting hair thinning, hormone balance, and overall wellness; sold via the Caitera e-commerce site.
• Tutti Skincare Direct-to-consumer skincare line marketed alongside SottoPelle's hormone therapy programs, providing skin care products for patients seeking hormone-related skin health benefits.
• Bolster Beauty Affiliate consumer beauty brand under the SottoPelle umbrella, sold direct-to-consumer as part of the company's wellness and beauty product portfolio.

Quantifiable outcome

• 4x greater increase in bone density than oral estrogen and 2.5x greater than patch delivery methods
• +2 more outcomes

Named customers2 records

Segments6 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature2 records

Partnerships

One partnership is on record.

• Draft Nation PodcastminorGTM or Marketing Partner · 10 April 2024SottoPelle sponsors the Draft Nation Podcast, a sports-focused show covering the latest in sports, strategy, and drafting. The partnership aligns SottoPelle with performance-oriented audiences including athletes and sports enthusiasts who may benefit from hormone therapy for injury recovery, cognitive function, and vitality.

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Pellecome: Pellecome is a competing BHRT pellet therapy brand offering provider training, dosing methodology, and hormone pellet products. It targets a similar physician audience and patient demographic, making it a close substitute for SottoPelle's training-and-supply stack.
• Defy Medical: Defy Medical is a telehealth and clinic-based HRT provider offering bio-identical hormone therapies, including pellets, to men and women. It overlaps with SottoPelle's clinical indications and increasingly competes for patients who prefer remote or non-traditional delivery channels.
• Evexipel: Evexipel provides bio-identical hormone pellet therapy training and certification for physicians alongside proprietary pellet products. It competes head-to-head with SottoPelle for provider adoption, dosing technology differentiation, and patient outcomes claims in the same menopausal/andropause market.
• BioTE Medical: BioTE Medical is the largest direct competitor in subcutaneous BHRT pellet therapy, training and certifying medical providers in a parallel methodology and supplying hormone pellets through its own distribution network. Both companies monetize the same provider-training-plus-pellet-supply B2B2C model serving menopause, andropause, and adjacent indications.
• ReVital (Revitalization Clinic network): ReVital is a multi-state wellness clinic operator offering pellet-based BHRT, weight management and wellness services. It overlaps directly with SottoPelle's clinical indications while competing for both providers and patients in the same geographic markets.

Broad incumbents

• Bayer (Climara, estradiol franchise): Bayer sells transdermal estradiol patches and combination HRT products used for menopause symptom management. It competes with SottoPelle's pellet offering for the same indication and patient demographic, but through a fundamentally different delivery modality and at large pharmaceutical scale.
• AbbVie (estradiol franchise): AbbVie markets synthetic estradiol and combined HRT products (e.g., Estrace) and is a dominant incumbent in conventional HRT prescribing. While its delivery modalities differ from SottoPelle pellets, it competes for the same patients and physician prescribing budgets.
• Hims & Hers Health: Hims & Hers Health is a large direct-to-consumer telehealth platform that has expanded into hormone replacement therapy, testosterone support, and wellness. Its scale, brand, and capital put pricing pressure on SottoPelle's consumer-facing offerings and provider referrals, even though it does not offer pellet therapy.

Emerging players

• BodyLogicMD: BodyLogicMD is a national network of physician-owned wellness practices specializing in bio-identical hormone replacement therapy, alongside nutrition and weight-loss services. It competes with SottoPelle for BHRT-trained providers and for patients seeking individualized hormone optimization outside traditional primary care.
• AgelessRx: AgelessRx is a telehealth provider offering bio-identical hormone replacement therapy and longevity-focused treatments to consumers online. It competes with SottoPelle for hormone-optimization patients seeking convenient access, while operating in overlapping wellness and anti-aging positioning.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/SottoPelle
• YouTubeyoutube.com/user/SottoPelleTherapy
• Facebookfacebook.com/hormonereplacement
• Instagraminstagram.com/sottopelletherapy
• LinkedInlinkedin.com/company/sottopelle-therapy

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about SottoPelle