Essence Line

What Essence Line does

ESSENCE LINE, s.r.o. is a privately held Czech biotechnology company founded in 2001, headquartered in Prague 10 - Hostivař. It operates an in-house laboratory built on biochip and microarray platforms, next-generation sequencing (including Nanopore long-read), qPCR, and LC-MS/MS analytical chemistry, delivering molecular, genomic, proteomic, metabolomic, microbiomic, and toxicology analyses. The company is referenced as having more than 24 years of applied research experience in personalized medicine, molecular diagnostics, environmental safety, and biochip technology development.

The company serves two parallel end markets. On the consumer side, it sells home-collection diagnostic kits directly through its essenceline.cz e-shop, including dry blood spot tests (Cortisol, HbA1c, Vitamin D, NAD), microbiome tests (EssenceBIOM Gut and Dental), genetic tests, and bundled panels (e.g., Omega Ratio + OmegaHEPA), with prices ranging from a few hundred CZK for a single marker to over 5,500 CZK for a comprehensive pharmacogenetic panel. On the clinical/enterprise side, the company distributes point-of-care diagnostic devices and cartridges under the xPOC brand (Vitamin D xPOC, FSME IgG xPOC, PerioPOC Pro) co-developed with Genspeed Biotech, and provides professional laboratory testing services in pharmacogenetics (PharmEssence), metabolomics (OmegaESSENCE), proteomics, and toxicology to dental clinics, GP practices, clinical laboratories, and research and pharmaceutical partners.

Monetization is primarily transactional: one-time payments for home tests, laboratory services, and POCT cartridges, with consumable cartridge economics supporting B2B clinical accounts. The company is wholly domestic, with operations and distribution limited to Czechia, no disclosed external funding, and a small team of approximately 9 employees.

Name

Essence Line

Legal name

ESSENCE LINE, s.r.o.

Website

https://essenceline.cz

Company type

Private

Founded year

2001

Operating status

Operating

Headcount range

1–10 employees

Short description

ESSENCE LINE, s.r.o. is a Czech molecular diagnostics company operating an in-house biochip, NGS, and LC-MS/MS laboratory, offering home-collection diagnostic kits via e-shop (DBS, microbiome, pharmacogenetics) and B2B point-of-care cartridges and laboratory services to Czech dental clinics, GP practices, and research partners.

Ownership category

akta.pro rank

Product category

Molecular Diagnostics

NAICS

Medical Laboratories (621511), Medical and Diagnostic Laboratories (6215), In-Vitro Diagnostic Substance Manufacturing (325413), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Medical Laboratories (8071), In Vitro & In Vivo Diagnostic Substances (2835), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Specialty & Biomarker Laboratory Services (Immunoassays/Flow/Cytometry) (HLAGAEAB)

akta.pro secondary industries

Clinical Chemistry & Immunoassay Laboratories (HLAFAMAB), Bioanalytical & PK/PD Sample Analysis (Trial Support) (HLAGAEAG), Clinical Chemistry, Hematology & Coagulation Testing (Trial Support) (HLAGAEAE)

Keywords

• Molecular diagnostics
• Home diagnostic testing
• Pharmacogenetic testing
• Microbiome profiling
• Point-of-care diagnostics

Headquarters

HQ city

Prague 10 - Hostivař

HQ country

Czechia

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure, Supply Chain, Marketing or Sales

Revenue model

1. Home Diagnostic Testing: Sale of home collection diagnostic tests including dry blood spot tests (cortisol, vitamin D, HbA1c, NAD), microbiome tests (gut, oral), and genetic tests. Consumers purchase kits, collect samples at home, send to laboratory, and receive digital reports.
2. Professional Laboratory Services: Clinical laboratory testing services for genetics, metabolomics, proteomics, microbiome, and energy metabolism sold to clinics, healthcare providers, and research institutions.
3. Point-of-Care Diagnostics: Sale of POCT devices and cartridges (Vitamin D xPOC, FSME IgG xPOC, PerioPOC Pro) to clinical partners including dental clinics and GP practices for same-visit testing.
4. Custom Molecular Testing: Bespoke molecular genetic testing services tailored to specific clinical needs, indications, or research assignments for laboratory and clinical partners.

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels4 records

Core offering

Essence Line develops and delivers molecular diagnostic and analytical services spanning home dry blood spot tests (cortisol, omega ratio, NAD, vitamin D, HbA1c), microbiome diagnostics (EssenceBIOM Gut and Dental), pharmacogenetic testing (PharmEssence), metabolomic/proteomic analyses, and point-of-care diagnostic cartridges (Vitamin D xPOC, FSME IgG xPOC, PerioPOC Pro) for clinical partners, alongside professional laboratory testing services for clinics, dental practices, research institutions, and pharmaceutical/CRO partners.

Product overview

Essence Line offers a portfolio of diagnostic products organized across six main categories: (1) Home Dry Blood Spot Tests including Cortisol, Omega Ratio, NAD Level, Vitamin D, and HbA1c tests; (2) Microbiome Diagnostics under the EssenceBIOM brand covering intestinal (EssenceBIOM Gut) and oral (EssenceBIOM Dental) testing; (3) Genetic/Pharmacogenetic Testing including PharmEssence (90 drugs, 22 genotypes) and targeted gene panels; (4) Point-of-Care Diagnostics under the xPOC brand including Vitamin D xPOC, FSME IgG xPOC, and PerioPOC Pro; (5) Metabolomic and Proteomic Services including omega fatty acids, Klotho protein, NAD+/NADH, and multiplex protein marker analysis; and (6) Laboratory Equipment including VistaLab pipettes. The offering combines home self-collection diagnostics with clinical point-of-care solutions and professional laboratory services.

Differentiator

Problem solved

Functional benefit

Brands

• EssenceBIOM: Microbiome testing brand including EssenceBIOM Gut (intestinal microbiome profiling) and EssenceBIOM Dental (oral microbiome profiling)
• PharmEssence
• OmegaESSENCE
• xPOC
• Klotho protein
• NAD

Products and services

• Cortisol test Home dry blood spot diagnostic test for evaluating stress load and HPA axis rhythm, providing interpretation of morning and evening cortisol patterns for individual consumers.
• Omega ratio test Home dry blood spot test measuring omega-3, omega-6, and omega-9 fatty acid levels with indices including omega-3 index, AA:EPA ratio, trans fat index, and omega-6:omega-3 ratio for cardiometabolic assessment.
• NAD level test Home dry blood spot test measuring NAD levels for cellular metabolism, vitality, and regeneration assessment, particularly relevant for individuals considering NR, NMN, or NAD supplementation.
• Vitamin D test Home test measuring vitamin D2 and D3 levels as indicators of immunity, bone health, and overall vitality, with laboratory interpretation of results.
• HbA1c test Home test measuring HbA1c as a long-term blood glucose marker reflecting average glycaemia over the preceding 2-3 months, used for diabetes risk assessment and prediabetes monitoring.
• EssenceBIOM Gut Comprehensive intestinal microbiome profiling from a home stool sample covering microbial diversity, Firmicutes/Bacteroidetes ratio, probiotic bacteria, SCFA producers, and pathogen screening.
• EssenceBIOM Dental Functional oral microbiome profile from interdental plaque evaluating protective capacity, acidogenic potential, cariogenic index, periodontal risk, halitosis profile, and microbial diversity.
• PharmEssence Pharmacogenetic analysis covering 90 drugs and 22 genotypes across 10 therapy areas, analyzing variants influencing drug metabolism, efficacy, and adverse reaction risk for clinical and laboratory partners.
• OmegaESSENCE Fatty acid profile test measuring 26 fatty acids with five indices including omega-3 index and omega-6:omega-3 ratio, provided as a dry blood spot home diagnostic and as a professional laboratory service.
• Vitamin D xPOC Rapid vitamin D testing cartridge for clinical settings, providing fast laboratory-quality results during a single patient visit without external laboratory delays.
• FSME IgG xPOC Rapid FSME IgG antibody testing cartridge for point-of-care use, enabling same-visit diagnostic information without external laboratory delays for clinical partners.
• PerioPOC Pro Point-of-care diagnostic solution for dental clinics and dental laboratories, providing chairside diagnostic context with same-visit results.
• VistaLab (Ovation) pipettes Professional laboratory pipettes and related accessories for laboratory use, sold as laboratory equipment in the Essence Line e-shop.
• Custom molecular genetic testing services Bespoke molecular genetic testing services tailored to specific clinical indications, research assignments, or laboratory partner needs, with individual pricing by agreement.
• Omega ratio test + OmegaHEPA bundle Combined home test bundle pairing the Omega Ratio fatty acid profile with the OmegaHEPA genetic add-on panel, providing long-term context for lipid metabolism and supplementation response.

Quantifiable outcome

• 90 drugs analyzed, 22 genotypes tested, 10 therapy areas in PharmEssence pharmacogenetics panel
• +3 more outcomes

Segments4 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature7 records

Partnerships

Five partnerships are on record, tiered core and supporting.

• Research Centres and UniversitiescoreStrategic or Co-development PartnerEssence Line collaborates with academic and research institutions on applied biotechnology research, molecular diagnostics development, and translational science projects. The company participates in national and international research and innovation projects focused on precision medicine, neurodegenerative disorders, molecular diagnostics, biochip technologies, and AI-assisted interpretation of genomic and metabolomic data.
• Pharmaceutical CompaniescoreStrategic or Co-development PartnerPartnerships with pharmaceutical companies for pharmacogenomics research, drug metabolism analysis, and clinical support services. The company analyzes variants influencing drug metabolism, efficacy, and adverse reaction risk across psychiatry, oncology, cardiology, pain management, and other therapy areas.
• CRO PartnerssupportingImplementation/ SI/ Consulting PartnerCollaboration with Contract Research Organizations for toxicology studies, environmental safety assessment, and xenobiotic monitoring services supporting clinical and industrial research.
• Clinical and Laboratory TeamscoreChannel Partner/ Reseller/ DistributorPartnerships with clinical laboratories, dental clinics, and GP practices for point-of-care diagnostics implementation, laboratory testing services, and clinical decision support through PharmEssence and other diagnostic solutions.
• Industrial and Technology PartnerssupportingTechnology or IntegrationPartnerships with technology providers including Affymetrix, Illumina, Agilent platforms for microarray and biochip technologies, as well as Genspeed Biotech for point-of-care diagnostic devices (Vitamin D xPOC, FSME IgG xPOC).

Scale indicators2 records

Recent moves5 records

Expansion highlights5 records

Broad incumbents

• Eurofins Genomics: Global genomics services division of Eurofins Scientific, offering DNA sequencing, microarrays, and bioanalytical services. Comparable for the underlying microarray/qPCR/sequencing capabilities and custom molecular testing services.
• Synlab: Europe's largest medical diagnostics services provider, operating clinical labs across the continent including the Czech Republic. Comparable as a broad incumbent serving clinicians with reference laboratory services, against whom Essence Line competes for clinical B2B work.

Direct peers

• Viome: US-based direct-to-consumer microbiome and RNA-based wellness testing company. Comparable for the EssenceBIOM microbiome franchise and consumer-driven preventive health go-to-market.
• DayTwo: Microbiome-based personalized nutrition company combining gut microbiome profiling with dietary recommendations. Comparable for the gut microbiome testing offering and health-actionable consumer positioning.
• Thriva: UK DTC blood biomarker testing company using home finger-prick dry blood spot collection. Closely comparable to Essence Line's DBS-style home diagnostic tests (cortisol, vitamin D, HbA1c, NAD) and consumer e-commerce model.
• 24Genetics: European (Spain-based) DTC genetic testing company offering health, ancestry, and pharmacogenomic panels across multiple EU markets. Comparable for multi-test DTC genetic offering and EU-wide consumer reach.
• Atlas Biomed: UK-based direct-to-consumer microbiome and DNA testing company. Comparable for DTC microbiome (EssenceBIOM Gut/Dental) and genetic testing, e-commerce-led go-to-market, and consumer health positioning.
• Novogenia: Austrian clinical laboratory offering direct-to-consumer and B2B pharmacogenetic, microbiome, and genetic testing. Most directly comparable peer: matches Essence Line's multi-omic DTC-plus-clinical lab model in a neighboring Central European market.
• GHC Genetics: Czech genetics and clinical diagnostics laboratory operating in the same domestic market. Comparable product mix (genetic testing, clinical diagnostics) and overlapping customer base (Czech clinics, hospitals, consumers).
• bio.logis: German pharmacogenomics lab providing PGx interpretation and IT platforms for clinical decision support. Comparable for the PharmEssence-style PGx offering and clinical-partner GTM.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks5 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/essence-line

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Essence Line