What Reply Fertility does

Reply Fertility (legal entity: Reply Ob/Gyn & Fertility, LLC) is a private medical practice founded in 2015 and headquartered in Durham, North Carolina, specializing in Restorative Reproductive Medicine (RRM), a clinical discipline that diagnoses and treats underlying causes of infertility rather than bypassing them through IVF. The practice operates three core clinical programs — Infertility, Miscarriage Prevention, and Gynecology — anchored by a 55-factor underlying-cause assessment protocol that identifies typically 4–6 contributing conditions per couple. Supporting services include Fertility Awareness Education (teaching Sensiplan, Listen Fertility, Billings Ovulation Method, and Marquette Model methods), Health Coaching (nutrition, sleep, exercise, stress, environmental exposures), IUI, fertility preservation (egg/embryo/sperm freezing), and minimally invasive laparoscopic/hysteroscopic surgery.

The company employs approximately 16–19 staff including physicians, certified nurse midwives, RNs, fertility educators, and a case manager, with Medical Director John M. Thorp Jr., MD and Owner David Merrill, MD providing clinical leadership. Revenue is generated primarily through self-pay clinical program fees at 1/3 to 1/2 the cost of IVF, with HSA/FSA eligibility and CareCredit financing; supplementary streams include a B2B Employer Fertility Benefits Program, an online retail store selling Sensiplan educational bundles and basal body thermometers, and telehealth-delivered services statewide in North Carolina and Michigan. Distribution is direct-to-consumer with free 15-minute consultations as the top-of-funnel, supported by vcita online scheduling and athenahealth for patient portal/EHR. Clinical credibility is reinforced through participation in the International Institute for Restorative Reproductive Medicine (IIRRM) and the STORRM international outcomes research registry. The practice has served thousands of patients since inception and reports 50% pregnancy rates at 12 months and 69% at 18 months for RRM patients.

Name

Reply Fertility

Legal name

Reply Ob/Gyn & Fertility, LLC

Website

https://replyfertility.com

Company type

Private

Founded year

2015

Operating status

Operating

Headcount range

11–50 employees

Short description

Reply Fertility is a private Durham, NC medical practice founded in 2015 that delivers Restorative Reproductive Medicine (RRM) to identify and treat underlying causes of infertility, serving individual couples across North Carolina and Michigan via in-person clinic visits and telehealth, with supplementary employer fertility benefits and fertility awareness education products.

Ownership category

akta.pro rank

Product category

Reproductive Healthcare Services

NAICS

Family Planning Centers (621410)

SIC

Services-Offices & Clinics Of Doctors Of Medicine (8011), Services-Health Services (8000)

akta.pro primary industry

Fertility, Reproductive Endocrinology & IVF Centers (HLAFAJAD)

akta.pro secondary industries

Reproductive Endocrinology & Infertility (IVF/Fertility) (HLAKAJAC), Fertility & Reproductive Endocrinology Telehealth (IVF/IUI, infertility evaluation) (HLALAHAA)

Keywords

• Restorative reproductive medicine
• Fertility treatment services
• Infertility diagnosis
• Fertility awareness education
• Recurrent miscarriage care

Headquarters

HQ city

Durham

HQ country

United States

HQ region

North America

Offices8 records

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales

Revenue model

1. Clinical Infertility Programs: Fee-for-service clinical programs for infertility treatment, miscarriage prevention, and gynecology. Self-pay model with payment required in advance of services. Program fees discussed at free consultation or following initial clinician visit.
2. Fertility Awareness Education: Fertility awareness education services including cycle tracking instruction and coaching on lifestyle factors such as nutrition, exercise, sleep, and stress management
3. Product Sales: Sale of fertility-related educational products including Sensiplan materials, basal body thermometers, and decision-making tools through the clinic store
4. Employer Partnership Programs: Fertility benefit programs offered to employers as employee wellness benefits, providing RRM care to covered employees

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels7 records

Core offering

Reply Fertility is a physician-owned medical practice that provides Restorative Reproductive Medicine (RRM), diagnosing and treating the underlying causes of infertility and reproductive dysfunction rather than bypassing them through IVF. Its offerings include three clinical programs (Infertility, Miscarriage, Gynecology), fertility awareness education, health coaching, telehealth, intrauterine insemination (IUI), fertility preservation, and minimally invasive fertility surgery.

Product overview

Reply Fertility offers a unified platform of restorative reproductive medicine (RRM) services focused on diagnosing and treating the underlying causes of infertility to help couples conceive naturally, without defaulting to IVF. The core offering consists of three clinical programs: the Infertility Program (identifying and treating 4-6 underlying factors in both female and male partners), the Miscarriage Program (risk assessment and prevention of recurrent pregnancy loss), and the Gynecology Program (addressing conditions like PCOS and endometriosis). These clinical programs are supported by complementary services including Fertility Awareness Education (offering multiple methods: Sensiplan, Listen Fertility, Billings Ovulation Method, and Marquette Model), Health Coaching (lifestyle optimization around nutrition, sleep, exercise, stress, and environment), Telehealth consultations (including free initial consults), and Intrauterine Insemination (IUI) as a minimally invasive treatment step. Fertility preservation services (egg, embryo, and sperm freezing) and minimally invasive fertility surgery (laparoscopy and hysteroscopy) are available for patients with specific clinical needs. An online store sells Sensiplan educational materials (handbook, workbook, bundles, and the Total Package), basal body thermometers, and decision-making tools. A separate Employer Fertility Benefits Program offers RRM care as a corporate employee benefit. The portfolio is connected through a unified patient journey: initial telehealth consultation → comprehensive diagnostic testing → personalized treatment plan across applicable programs → ongoing health coaching and fertility awareness education for cycle tracking.

Differentiator

Problem solved

Functional benefit

Brands

• KNDR HealthCare: A healthcare brand mentioned as part of the Reply ecosystem alongside Reply Fertility

Products and services

• Infertility Program A clinical care program for individuals and couples struggling to conceive, using RRM to diagnose and treat root causes such as hormonal, metabolic, structural, or cycle-related factors through medical, surgical, and lifestyle interventions.
• Miscarriage Program A clinical program for patients with a history of pregnancy loss that uses RRM evaluation and treatment to identify and address underlying contributors to miscarriage and support subsequent pregnancies.
• Gynecology Program A clinical program providing RRM-based gynecologic care for conditions such as endometriosis, PCOS, PMS/PMDD, irregular cycles, and other hormone- or cycle-related concerns that often underlie fertility issues.
• Fertility Awareness Education

Quantifiable outcome

• 50% natural conception within 12 months; 69% natural conception within 18 months for RRM patients
• +3 more outcomes

Named customers10 records

Segments8 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration7 records

Feature5 records

Partnerships

Five partnerships are on record, tiered core and minor.

• International Institute for Restorative Reproductive Medicine (IIRRM)coreStrategic or Co-development PartnerCollaboration with IIRRM - the global professional organization for restorative reproductive medicine. Reply Fertility participates in the international research registry (STORRM) and is recognized as a member committed to exceptional care standards in RRM.
• Surveillance of Treatment Outcomes for Restorative Reproductive Medicine (STORRM)coreStrategic or Co-development PartnerParticipation in the international research registry tracking treatment outcomes for RRM enables evidence-based practice and contributes to global knowledge base for restorative reproductive medicine.
• CareCreditminorOthersThird-party financing partner providing flexible payment options for patients. Reply offers CareCredit as a financing option for self-pay services.
• Saint Paul VI InstitutecoreStrategic or Co-development PartnerRRM training partner for Dr. Kimberly Barrows - NaPro Technology Medical Consultant training through Saint Paul VI Institute, Omaha, NE
• FEMM FoundationcoreStrategic or Co-development PartnerRRM training partner for Dr. Kimberly Barrows - FEMM Medical Management training through FEMM Foundation

Scale indicators6 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Progyny: Public employer fertility benefits platform that contracts with fertility clinics including IVF providers. Competes directly with Reply's employer fertility benefits program in the B2B channel.
• CCRM Fertility: Large multi-state fertility clinic network offering conventional IVF with strong outcomes data. Represents the mainstream alternative to Reply's RRM positioning for patients willing to pay for IVF.
• Reproductive Medicine Associates (RMA): Established fertility clinic network focused on IVF and reproductive endocrinology. Operates in multiple states and competes for patients seeking traditional fertility treatment.
• Carrot Fertility: Global fertility benefits platform serving employers. Competes with Reply's employer partnership program by offering a broader network of IVF-centric clinics and a more established enterprise sales motion.
• Kindbody: Tech-enabled fertility clinic and employer benefits provider with multi-state physical clinics. Competes for employer fertility benefits contracts and broader patient market with a more conventional IVF-centric model.

Direct peers

• FEMM Foundation: FEMM provides RRM medical management training and patient education. Reply's Dr. Barrows received FEMM training through FEMM Foundation, and Reply teaches the Billings Ovulation Method in its clinic, making FEMM a direct methodological peer.
• Billings Ovulation Method Association: Organization teaching the Billings Ovulation Method, one of the four fertility awareness methods taught at Reply Fertility. Shares educational and ideological positioning with Reply on natural family planning.
• Saint Paul VI Institute: The leading NaPro Technology training and clinical organization. Reply Fertility's Dr. Kimberly Barrows received NaPro Technology Medical Consultant training here, making it the most direct methodological peer and a training pipeline partner.

Emerging players

• Maven Clinic: Virtual women's and family health platform with employer contracts, overlapping with Reply's telehealth fertility care model and competing for the same employer benefits dollar.

Others

• Marquette University College of Nursing (Marquette Model): Academic source for the Marquette Model of fertility awareness taught at Reply. Functions as a knowledge/training partner rather than a direct clinical competitor.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/reply-fertility

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Reply Fertility