SYADEM

What SYADEM does

SYADEM SAS is a French software publisher founded in 2009 as a non-profit and incorporated in 2012, headquartered in Bordeaux with €152,100 of share capital. The company specializes in vaccination decision support and operates a modular Immunisation Information System (IIS, branded SIV) covering the full vaccination lifecycle — from citizen education and decision support to professional practice management and public-health surveillance. Its core technology stack comprises NUVA (an international, multilingual vaccine nomenclature now recognized as a SNOMED CT community extension), SADV (a deterministic rule-based engine that generates personalized, clinically validated vaccination recommendations updated within 48 hours of official guideline publication), CVN (a lifelong digital vaccination record), Colibri (SaaS for vaccination centres), Mentor Pro/Citoyen (decision-support interfaces), CNV (digital vaccination card with QR code and cryptographic signature), and a Vaccination Monitoring Dashboard. The platform is built on REST APIs, OAuth 2.0/OpenID Connect, FHIR/HL7 interoperability, and JWT/EVC-based contextual patient linking.

The company generates revenue through four streams: subscription-based professional licenses (CVN Pro / Mentor Pro accessed via Pro Santé Connect), institutional and government licensing for national and regional IIS deployments, API/SDK licensing to EHR vendors and clinical software integrators, and freemium consumer services funded by institutional partners such as the Groupe d'Etudes en Préventologie (France) and Agence e-Santé (Luxembourg). Its go-to-market combines self-serve public web applications, enterprise field sales to governments, API-first distribution to software publishers, and event-driven deployments (e.g., HPV vaccination campaigns in 12 French regions). Deployments span 8 European countries — France, Luxembourg, Belgium, Latvia, Poland, Germany, Greece, and Portugal — with over 200 vaccination centres using Colibri and millions of citizens using MesVaccins.net in France. The company has secured regulatory validation through WHO Vaccine Safety Net membership (2016), an official SNOMED International partnership (2024), ECDC IIS report participation (2018), and inclusion in EU4Health and Horizon Europe projects (2020-2025).

Name

SYADEM

Legal name

SYADEM SAS

Website

https://syadem.com

Company type

Private

Founded year

2009

Operating status

Operating

Short description

SYADEM SAS is a Bordeaux-based French software publisher specializing in vaccination decision support, operating a modular Immunisation Information System (SIV) used by 8 European countries' health authorities, vaccination centres, and millions of citizens via MesVaccins.net.

Ownership category

akta.pro rank

Product category

Immunisation Information Systems / Vaccination Decision Support Software

NAICS

Computer Systems Design Services (541512), Computer Systems Design and Related Services (5415), Custom Computer Programming Services (541511)

SIC

Services-Prepackaged Software (7372), Services-Computer Integrated Systems Design (7373), Services-Health Services (8000)

akta.pro primary industry

Public Health & Immunization Data Exchange (ELR, case reporting, registry reporting) (HLACABAL)

akta.pro secondary industries

Consent, Documentation & Certification (Records/Passports/Proof of Vaccination) (HLAJAHAM), Immunization & Vaccination Programs Administration (BPAIAJAD), National/State/Local Immunization Program Offices (HLAJAHAA)

Keywords

• Vaccination decision support
• Immunization information systems
• Digital vaccination records
• Vaccine terminology nomenclature
• Public health software

Headquarters

HQ city

Bordeaux

HQ country

France

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Software

Cost components

Technology or R&D, Personnel, Operations, Infrastructure, Marketing or Sales

Revenue model

1. Professional Subscriptions (CVN Pro / Mentor Pro): Healthcare professionals (physicians, pharmacists, nurses, midwives) subscribe to CVN Pro for premium access to validated vaccination records, team collaboration, and personalised recommendations. Mentor Pro is accessible exclusively through CVN Pro Premium subscription or third-party iframe integration. Financing available for pharmacy networks (e.g., URPS Auvergne Rhône-Alpes funded CVN access for all pharmacies in the region from 2023 to 2025).
2. Institutional / Government Licensing: National vaccination platforms (IIS) deployed for governments and health authorities in Luxembourg, France, Belgium, Latvia, Poland, Germany, Greece, and other countries. Includes deployment of CVN, SADV instances, Dashboard, and Colibri. Part of EU4Health and Horizon Europe projects (2020-2025). Commissioned and financed by public health bodies.
3. API and SDK Licensing to Software Integrators: Patient software publishers and EHR vendors integrate SADV API, NUVA terminology, and VaccinationProfile nomenclature into their own products. Libraries available for Ruby, Python, TypeScript, and PHP. Authentication tokens provided by Syadem upon request ([email protected]).
4. Free Citizen Services: Free digital vaccination record services for citizens: MesVaccins.net (operated for Groupe d'Etudes en Préventologie in France) and the national Electronic Vaccination Record for Luxembourg (operated for Agence e-Santé). Mentor Citizen provides free anonymous vaccination advice. These services drive user acquisition and public health mission.

Pricing tiers

Go-to-market motion4 records

Distribution channels5 records

Marketing channels6 records

Core offering

SYADEM develops and operates a modular Immunisation Information System (SIV) for vaccination, combining the SADV deterministic rule-based decision support engine, the NUVA multilingual vaccine nomenclature, the CVN lifelong digital vaccination record, the Colibri SaaS vaccination centre management platform, the Tableau de bord monitoring dashboard, and Mentor / CNV citizen-facing tools. The platform generates personalised vaccination recommendations updated within 48 hours of official guideline publication, supports interoperability with FHIR, HL7, SNOMED CT, and national health systems, and is deployed for citizens, healthcare professionals, vaccination centres, and national health authorities across multiple European countries.

Product overview

SYADEM is a French software publisher co-founded by computer engineers and physicians, specializing in intelligent medical decision support with a focus on vaccination and preventive medicine. The company operates a modular Immunisation Information System (IIS / SIV) built around three core pillars: (1) NUVA — a multilingual vaccine nomenclature and terminology standard; (2) SADV — a deterministic rule-based vaccination decision support engine; and (3) CVN — a digital vaccination record infrastructure. The product portfolio includes consumer-facing tools (Mentor Citizen, CNV), professional tools (Mentor Pro, CVN Pro, Colibri), and authority tools (Dashboard). All components are interoperable via REST APIs supporting FHIR, SNOMED CT, and national health information systems, and are deployed across France, Luxembourg, and several other European countries.

Differentiator

Problem solved

Functional benefit

Brands

• MesVaccins.net: Digital vaccination record (carnet vaccinal numérique) operated by SYADEM for the Groupe d'Etudes en Préventologie in France, and as a national electronic vaccination record for Luxembourg's Agence e-Santé.
• Mentor
• Colibri
• NUVA
• SADV

Products and services

• SIV (Système d'Information pour la Vaccination) Modular, interoperable Immunisation Information System (IIS) combining NUVA, SADV, Colibri, CVN, CNV, and Dashboard as autonomous or combinable software bricks for national and regional health authorities.
• NUVA (Nomenclature Unifiée des Vaccins) International, multilingual, structured vaccine terminology covering all vaccines (commercial, historical, generic, country-specific), built on the valence model and mapped to 20+ external coding systems including CIS, CIP, CVX, SNOMED CT, ATC, and GTIN. Licensed for integration by software vendors and EHR publishers.
• SADV (Système d'Aide à la Décision Vaccinale) Expert SaaS software module that automatically generates personalised, clinically justified, and verifiable vaccination recommendations based on vaccination history, demographics, medical conditions, occupational exposures, and travel plans. Delivered via REST API, SDK clients, and embedded web components for citizens, professionals, and health authorities.
• Mentor Pro Professional vaccination decision-support tool analysing patient history, clinical characteristics, and living/working conditions to generate personalised recommendations. Accessible on all devices, requires only age and sex, and stores no personal data.
• Mentor Citoyen Free anonymous vaccination advice service for the general public accessible via MesVaccins.net and Mon espace santé, guiding users through a 4-step process (demographics, health profile, vaccination history, personalised schedule) with no data storage.
• CVN (Carnet de Vaccination Numérique) Lifelong, structured, secure digital vaccination record supporting citizen-initiated and provider-initiated modes, DataMatrix scanning, professional validation, and interoperable sharing. Deployed in France (MesVaccins.net) and Luxembourg (CVE), and accessible to healthcare professionals via CVN Pro.
• CNV (Carte Numérique de Vaccination) Enriched PDF document held by the citizen containing their complete vaccination history, a scannable QR code, embedded importable metadata, and a cryptographic digital signature based on the NUVA terminology and EVC format for cross-border portability.
• Colibri SaaS professional software for vaccination centres, health centres, occupational health services, and medico-social organisations, delivered 100% via web browser. Manages patients, consultations, vaccination traceability, scheduling, stock, billing, and integrates SADV decision support, FHIR/HL7 interoperability, and INSi patient identification.
• Tableau de bord (Vaccination Monitoring Dashboard) Real-time dynamic analytics tool for health authorities that aggregates anonymised data from CVN, Colibri, and compatible sources, providing granular coverage indicators by age, risk group, geography, and condition, plus automated error and anomaly detection.

Quantifiable outcome

• 200+ vaccination centres equipped across 13 regions in France
• +4 more outcomes

Named customers6 records

Segments8 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration13 records

AI capability8 records

Feature8 records

Partnerships

Nine partnerships are on record, tiered core and minor.

• SNOMED InternationalcoreStrategic or Co-development Partner · 1 January 2024Official partnership signed in 2024 to integrate NUVA as a community extension to SNOMED CT, the world's most comprehensive clinical healthcare terminology. This recognition establishes NUVA as an international standard and enables semantic interoperability between national vaccine coding systems and SNOMED CT globally.
• URPS Pharmaciens Auvergne Rhône-AlpescoreChannel Partner/ Reseller/ Distributor · 1 January 2023Regional union of pharmacists in Auvergne Rhône-Alpes region. URPS finances access to CVN (MesVaccins.net) for all pharmacies in the region from 2023 to 2025, enabling pharmacists to use digital vaccination records for patient traceability and coordination with physicians.
• Agence e-Santé LuxembourgcoreStrategic or Co-development Partner · 1 January 2020Government agency responsible for digital health in Luxembourg. SYADEM deployed the national Electronic Vaccination Record (CVE) platform for Luxembourg in 2020. SYADEM operates the platform on behalf of the Luxembourg government.
• EU4Health / Horizon EuropeminorStrategic or Co-development Partner · 1 January 2020SYADEM participates in European Union health programmes (EU4Health and Horizon Europe, 2020-2025) involving deployment of immunisation information components in Luxembourg, Latvia, Belgium, Poland, Germany, and Greece.
• Service de Santé Universitaire de Lyon IminorStrategic or Co-development Partner · 1 January 2020University health service at Lyon I using CVN to collect and validate vaccination records of health students required to complete internships.
• European Centre for Disease Prevention and Control (ECDC)minorStrategic or Co-development Partner · 1 January 2018SYADEM participated in the ECDC Report on Immunisation Information Systems (IIS) in 2018, contributing expertise on vaccination information systems and standards.
• Groupe d'Etudes en Préventologie (GEP)coreStrategic or Co-development Partner · 1 January 2009Non-profit association of vaccination experts independent of the pharmaceutical industry. GEP provides the scientific and medical expertise that underlies all SYADEM products, writing and validating the vaccination decision rules. SYADEM operates MesVaccins.net on behalf of GEP in France.
• Santé publique FranceminorStrategic or Co-development PartnerFrench public health agency. Partnerships with ARS (Agences Régionales de Santé) and Santé publique France for vaccination campaigns and MesVaccins.net deployment across France.
• VERCELminorOthersVercel is listed as the web hosting provider for the syadem.com website and engineering documentation portal. Not a strategic partnership.

Scale indicators8 records

Recent moves7 records

Expansion highlights5 records

Emerging players

• Lifen: French health data interoperability platform connecting EHRs, hospitals, and software publishers. Comparable to SYADEM in providing integration infrastructure between clinical software and external services, including potential vaccination record sharing.
• Doctolib: France's leading digital health platform for appointment booking, teleconsultation and increasingly professional workflows. Comparable as a French consumer-and-professional health platform; potential overlap with SYADEM's professional vaccination workflows and citizen services via Mon espace santé integrations.
• Weda: French EHR vendor for general practitioners, widely deployed in French medical practices. Comparable as a target integration partner (and potential competitor) for embedding SADV decision support and CVN synchronisation inside primary-care workflows.

Broad incumbents

• Maincare Solutions: French health IT vendor supplying hospital information systems, EHRs and public-health platforms to French regional agencies and hospitals. Comparable as a French-based competitor for regional health authority and public-sector IT contracts adjacent to SYADEM's IIS deployments.
• InterSystems: Provider of health data platforms (HealthShare, IRIS for Health) widely used in European national health information exchanges. Overlaps with SYADEM's interoperability and FHIR-based integration capabilities and competes for the same public-sector data platform contracts.
• Dedalus: Major European healthcare IT vendor with broad hospital and public-health software suites across multiple EU countries. Comparable to SYADEM as a competing supplier of national-scale health information systems and EHRs into which vaccination workflows could be embedded.
• CompuGroup Medical: European healthcare software vendor providing physician practice, pharmacy, and hospital IT across Germany, France, and other EU countries. Comparable to SYADEM as a multi-country EHR/pharmacy vendor that could integrate or compete with vaccination decision support.
• Cegedim: French healthcare IT group with software used by physicians, pharmacists and health authorities. Comparable to SYADEM in serving the French healthcare professional and public-health segments, including pharmacist workflows where CVN Pro also competes.
• Epic Systems: Largest US EHR vendor with growing European footprint (e.g., NHS trusts, large hospital systems). Comparable as a broad incumbent whose native EHR could absorb vaccination decision support, positioning it as both a partner and a long-term competitive threat to SYADEM.

Others

• SNOMED International: Standards organisation behind SNOMED CT, with which SYADEM has an official 2024 partnership to publish NUVA as a CT extension. Not a competitor; included as an adjacent ecosystem participant whose endorsement materially validates SYADEM's terminology strategy.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

Compliance5 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about SYADEM