Affect
Affect Therapeutics is a U.S. digital health company that delivers fully virtual, insurance-covered treatment for substance use disorders and mental health conditions through its mobile app, combining contingency management rewards, telehealth therapy, psychiatry, and medication-assisted treatment.
- Company typePrivate
- Founded2020
- HeadquartersMclean, United States
- Headcount101–250
- GTM typeB2C
- OfferingServices
What Affect does
Affect Therapeutics, Inc. is a U.S.-based digital health company founded in 2020 and headquartered in McLean, Virginia, that delivers fully virtual, mobile-first treatment for substance use disorders and co-occurring mental health conditions. Its core product, the Affect App, integrates contingency management rewards (cash incentives up to $599), medication-assisted treatment, telehealth therapy and psychiatry, peer support, and progress tracking within a single iOS/Android application. The platform is HIPAA- and 42 CFR Part 2-compliant and holds CARF International accreditation, and has been used to treat 13,000+ individuals as of 2025.
The company serves adults in 20+ U.S. states and addresses alcohol, opioid, stimulant (cocaine, methamphetamine), and cannabis use disorders alongside mental health conditions such as anxiety, depression, PTSD, OCD, bipolar disorder, and postpartum depression. A standalone free Sober Tracker / Habit Counter tool extends reach to users not yet enrolled in treatment. Technology architecture centers on secure HIPAA-compliant video conferencing, in-app care team messaging, gamified rewards delivery, and integrated clinical workflows rather than on proprietary AI models.
Revenue is generated primarily through insurance reimbursement — Medicaid, Medicare, and commercial/Marketplace plans — with approximately 90% of members incurring zero out-of-pocket cost. The company also sells a referral channel and runs paid acquisition through Google Ads and social platforms. Affect has raised roughly $49 million across four disclosed rounds between April 2021 and September 2025, with the most recent $26 million Series B led by Allumia Ventures. The leadership team is founder-led, with co-founder Kristin Muhlner serving as CEO, Jeff De Flavio as Executive Chairman, and Russell Osborne as CTO, with a headcount of 101–250 employees.
Affect firmographics
Firmographics- Name
- Affect
- Legal name
- Affect Therapeutics, Inc.
- Website
- https://affect.com
- Company type
- Private
- Founded year
- 2020
- Operating status
- Operating
- Headcount range
- 101–250 employees
- Short description
- Affect Therapeutics is a U.S. digital health company that delivers fully virtual, insurance-covered treatment for substance use disorders and mental health conditions through its mobile app, combining contingency management rewards, telehealth therapy, psychiatry, and medication-assisted treatment.
- Ownership category
- akta.pro rank
Affect industry classification
Industry- Product category
- Digital Addiction and Mental Health Treatment
- NAICS
- Outpatient Mental Health and Substance Abuse Centers (621420), Outpatient Mental Health and Substance Abuse Centers (62142), Offices of Mental Health Practitioners (except Physicians) (621330)
- SIC
- Services-Health Services (8000), Services-Social Services (8300)
- akta.pro primary industry
- Psychiatry & Medication Management Platforms (HLALAEAB)
- akta.pro secondary industries
- Behavioral Health & Substance Use Remote Monitoring (HLACAFAD), Substance Use Recovery & Harm Reduction Support Services (BPAGAEAO)
Keywords
Where Affect is headquartered
LocationHeadquarters
- HQ city
- Mclean
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Affect business model
Business model- GTM type
- B2C
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Operations, Marketing or Sales
Revenue model
- Insurance Reimbursement: Services covered by health insurance including Medicaid, Medicare, and commercial employer/Marketplace plans. The company accepts numerous insurance providers across states. For 90% of members, treatment is entirely free after insurance coverage.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Monthly | Insurance-covered treatment program |
Go-to-market motion2 records
Distribution channels2 records
Marketing channels9 records
Affect product offering
Product offeringCore offering
Affect delivers a fully virtual, smartphone-based treatment program for adults with substance use disorders (alcohol, opioids, stimulants, cannabis) and mental health conditions (anxiety, depression, trauma/PTSD, bipolar, OCD, postpartum depression), combining licensed therapy, psychiatry, medication-assisted treatment, peer support, and a contingency management rewards system that pays up to $599 in cash for treatment milestones; services are billed through health insurance (Medicaid, Medicare, commercial, and Marketplace plans) and accessed via the Affect App on iOS and Android across 20+ U.S. states.
Product overview
Affect is a digital health company offering a unified smartphone-based treatment platform for addiction recovery and mental health care. The core product is the Affect App, which integrates multiple treatment modalities including telehealth therapy and psychiatry, medication-assisted treatment (MAT), contingency management with financial rewards up to $599, one-on-one counseling, group sessions, peer support, and progress tracking. The platform serves both addiction treatment (alcohol, opioids, stimulants, cannabis, and other substances) and mental health conditions (anxiety, depression, trauma/PTSD, bipolar disorder, OCD, postpartum depression). The program is covered by insurance including Medicaid and Medicare for approximately 90% of members. The company also offers a free standalone Sober Tracker for non-enrolled users.
Differentiator
Problem solved
Functional benefit
Products and services
- Affect App Smartphone app providing comprehensive digital treatment for mental health and addiction, integrating telehealth, therapy, psychiatry, medication management, contingency management rewards, and progress tracking for adult members in 20+ U.S. states.
- Addiction Treatment Program Digital treatment program for adults with alcohol, opioid, stimulant (cocaine, meth, crack), and cannabis use disorders, combining medication-assisted treatment, counseling, contingency management with cash rewards, and peer support delivered entirely through the Affect App.
- Mental Health Treatment Program Online mental health treatment for adults with anxiety, depression, trauma/PTSD, bipolar disorder, OCD, and postpartum depression, combining therapy, psychiatry, and medication management delivered virtually through the Affect App.
- Sober Tracker Free habit-tracking tool available within the Affect App that lets users count sober days, set recovery goals, and monitor progress over time without enrolling in the paid treatment program.
- Telehealth Platform HIPAA- and 42 CFR Part 2-compliant video conferencing and secure messaging platform enabling virtual therapy, psychiatry, counseling, and care team sessions from any location.
Quantifiable outcome
- 13,000+ people treated
- +5 more outcomes
Companies that use Affect
Customer profileNamed customers10 records
Segments4 records
Ideal customer profiles4 records
Affect technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature4 records
Affect partnerships and signals
Strategic signalScale indicators7 records
Recent moves6 records
Expansion highlights5 records
Affect competitors and assessment
Company assessmentDirect peers
- Pelago (formerly Quit Genius): Pelago is a virtual substance use management platform serving employers and health plans with digital addiction treatment across alcohol, opioid, and stimulant use disorders. Directly comparable to Affect in core SUD focus, contingency-management-adjacent model, and enterprise/payer distribution.
- Workit Health: Workit Health provides telehealth addiction treatment including medication-assisted treatment and counseling for opioid and alcohol use disorders. Closely comparable in digital-first SUD care delivery, insurance reimbursement model, and dual SUD + mental health focus.
- Boulder Care: Boulder Care is a telehealth provider focused on opioid use disorder treatment with medication-assisted treatment, counseling and peer support. Directly comparable virtual SUD model, multi-state licensure approach, and Medicaid-friendly payer mix.
- Ophelia: Ophelia is a telehealth platform providing medication-assisted treatment for opioid use disorder, with asynchronous clinician chat and remote prescribing. Directly comparable in virtual-first OUD treatment, insurance reimbursement, and state-by-state licensing model.
- Lionrock Recovery: Lionrock delivers online substance use disorder treatment via telehealth group sessions and individual counseling across multiple substance categories. Comparable as a virtual-first SUD provider serving individuals through employer and direct channels.
- Eleanor Health: Eleanor Health provides outpatient addiction and mental health treatment with a hybrid in-person and virtual care model, accepting Medicaid and commercial insurance. Comparable in integrated SUD + mental health offering and value-based payer relationships.
- Ria Health: Ria Health is a telehealth program focused specifically on alcohol use disorder combining medication, coaching, and digital tools. Comparable as a digital, telehealth-first SUD treatment platform serving insured and self-pay members.
- Brightside Health: Brightside Health is a telehealth mental health provider treating depression, anxiety and related conditions via medication and therapy. Comparable in virtual care delivery, insurance reimbursement, and the mental health arm of Affect's offering.
Emerging players
- Charlie Health: Charlie Health is a virtual intensive outpatient program for teens, young adults and adults struggling with mental health and substance use. Comparable in virtual outpatient SUD + mental health delivery, though focused on higher-acuity IOP-level care.
Broad incumbents
- Cerebral: Cerebral is a broader telehealth mental health provider that scaled quickly and subsequently retrenched amid ADHD prescribing scrutiny. Comparable in virtual mental health delivery model and payer-reimbursed revenue model, but a broader-portfolio incumbent rather than an SUD specialist.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat4 records
Key risks6 records
Key highlights7 records
Customer concentration
Affect social profiles
Digital presenceAffect financial estimates
Financial estimateRevenue estimate
Valuation estimate
Affect leadership team
Management profileNumber of profiles
Profiles7 records
Affect subsidiaries and ownership
Company hierarchySubsidiaries2 records
Affect funding detail
Funding detailFunding overview
Funding rounds4 records
Investors10 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Affect M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Affect
What does Affect do?
Affect delivers a fully virtual, smartphone-based treatment program for adults with substance use disorders (alcohol, opioids, stimulants, cannabis) and mental health conditions (anxiety, depression, trauma/PTSD, bipolar, OCD, postpartum depression), combining licensed therapy, psychiatry, medication-assisted treatment, peer support, and a contingency management rewards system that pays up to $599 in cash for treatment milestones; services are billed through health insurance (Medicaid, Medicare, commercial, and Marketplace plans) and accessed via the Affect App on iOS and Android across 20+ U.S. states.
Is Affect a public or private company?
Affect is a private company. It is classified as venture growth investor backed and is currently operating.
When was Affect founded?
Affect was founded in 2020. It employs 101 to 250 people.
Where is Affect based?
Affect is headquartered in Mclean, United States, in the North America region.
How does Affect make money?
One revenue line is on record: insurance Reimbursement.
Who are Affect's main competitors?
Direct peers on record are Pelago (formerly Quit Genius), Workit Health, Boulder Care, Ophelia, Lionrock Recovery, Eleanor Health, Ria Health and Brightside Health. Charlie Health is listed as an emerging player. Cerebral is listed as a broad incumbent.
Does Affect have an API?
No public API is recorded for Affect.
What industry is Affect in?
Affect's product category is Digital Addiction and Mental Health Treatment. Its primary akta.pro industry code is HLALAEAB, Psychiatry & Medication Management Platforms, with a secondary code of HLACAFAD, Behavioral Health & Substance Use Remote Monitoring. Its NAICS code is 621420 and its SIC code is 8000.