Zus Health

What Zus Health does

Zus Health is a privately held U.S. healthcare data interoperability company founded in 2020 by Jonathan Bush, the former CEO of Athenahealth. The company operates a FHIR-based shared health data platform that aggregates fragmented clinical information from national networks (CommonWell, Carequality, TEFCA via the Kno2 QHIN partnership), pharmacy networks (Surescripts), lab networks (Quest Diagnostics, Labcorp), and ADT networks (Bamboo Health, Collective Medical) into a unified patient record. Its cornerstone product, the Zus Aggregated Profile (ZAP), is supported by the Common Patient Record (CPR) layer that uses a proprietary Universal Patient Identifier (UPID) and enterprise master patient index to deliver a 96% patient match rate, transforming roughly 200 raw documents per patient into 1,000+ normalized FHIR resources through the proprietary Zus Lens enrichment engine.

The company's product portfolio spans the standalone Zus App, API & Components for embedded integrations, Zus Data Marts for analytics on Snowflake, Databricks, and BigQuery, and AI-powered features including Generated Patient Summary (GPS), risk suspecting (72.5% detection rate in pilots), and prospective risk adjustment. Zus serves value-based care organizations, ACOs, digital health startups, primary care practices, FQHCs, and Medicare Advantage plans, with named customers including Homeward Health, Author Health, Evergreen Nephrology, Firefly Health, Elation Health, and Pair Team. Distribution combines direct enterprise sales, a free developer sandbox, and embedded EHR partnerships with athenahealth, Elation Health, Healthie, Canvas Medical, Epic, eClinicalWorks, Medplum, and Salesforce.

Zus monetizes through enterprise subscription contracts billed annually, with tiered packages (Chart Build Lite and Chart Build Pro) and undisclosed pricing available on request. The company has raised approximately $74M across a $34M Series A led by Andreessen Horowitz (June 2021) and a $40M financing round (March 2023), and reported an eightfold revenue increase alongside 12 new clients over the trailing year through February 2025. Compliance posture includes SOC 2 Type II (2024) and CMS Interoperability Framework early-adopter recognition (2025), supporting a trust-focused GTM in regulated healthcare buyer environments.

Name

Zus Health

Legal name

Zus Health, Inc.

Website

https://zushealth.com

Company type

Private

Founded year

2020

Operating status

Operating

Headcount range

51–100 employees

Short description

Zus Health operates a FHIR-based shared health data platform that aggregates fragmented clinical records from national networks, pharmacies, labs, and ADT feeds into a unified patient profile for value-based care organizations, ACOs, digital health companies, and primary care providers via API, app, and EHR integrations.

Ownership category

akta.pro rank

Product category

Healthcare Data Interoperability Platform

NAICS

Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services (518210)

SIC

Services-Computer Programming, Data Processing, Etc. (7370), Services-Misc Health & Allied Services, Nec (8090)

akta.pro primary industry

Record Locator Services (RLS) & Longitudinal Record Aggregation (HLACABAH)

akta.pro secondary industries

Data Access, Sharing & Marketplace Platforms (incl. TEFCA/QHIN enablement) (HLACAIAL), FHIR/HL7 Data Repositories & Canonical Data Models (HLACAIAI), Healthcare Master Data Management (MDM) & Patient/Provider Identity Data (HLACAIAB), Real-World Data (RWD) Platforms & Clinical Data Curation (HLACAIAJ)

Keywords

• Healthcare data interoperability
• FHIR-based patient data
• Unified patient records
• Healthcare API platform
• Value-based care analytics

Headquarters

HQ city

Watertown

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Platform Subscription and Data Access: Zus Health generates revenue through subscription-based access to its healthcare data platform. Healthcare organizations pay for access to the Zus Aggregated Profile (ZAP), API access, and data services. The model includes different packages such as Chart Build Pro and Chart Build Lite with varying data retrieval capabilities.

Pricing tiers

Go-to-market motion2 records

Distribution channels5 records

Marketing channels10 records

Core offering

Zus Health operates a next-generation shared health data platform built on FHIR (Fast Healthcare Interoperability Resources) standards that aggregates patient clinical data from national networks, pharmacy networks, lab systems, and ADT feeds into a single, unified record. The platform is delivered via a standalone Zus App, FHIR/GraphQL APIs, embedded components, and direct EHR integrations, serving healthcare organizations, ACOs, value-based care providers, and digital health companies.

Product overview

Zus Health offers a unified, real-time healthcare data platform designed to accelerate healthcare data interoperability. The platform is built around the Zus Aggregated Profile (ZAP) as the cornerstone product, supplemented by the Common Patient Record (CPR) powered by Universal Patient Identifier (UPID) for patient identity management. Data delivery options include the standalone Zus App, API & Components for embedded integrations, and EHR integrations with athenahealth, Elation Health, Healthie, Canvas Medical, Epic, Salesforce, Medplum, and eClinicalWorks. Analytics capabilities are provided through Zus Data Marts available in Snowflake, Databricks, and BigQuery. The platform connects to national health information networks (CommonWell, Carequality, TEFCA), pharmacy networks (Surescripts), and ADT networks (Bamboo Health, Collective Medical). AI-powered features include Generated Patient Summary (GPS) for clinical summarization, risk adjustment capabilities with 72.5% detection rates, and prospective coding solutions surfacing conditions before 77% of encounters. Key clinical features include Hospitalization Summaries, Medication Journey Enrichment, Record Locator Service (96% match rate), and Chart Build Lite for patient history lookups.

Differentiator

Problem solved

Functional benefit

Brands

• ZAP (Zus Aggregated Profile): The cornerstone product providing a single, shareable view of a patient for care teams.
• Zus Aggregated Profile
• Zus Data Mart
• Zus App
• Zus API & Components
• Common Patient Record (CPR)
• Hospitalization Summaries
• Medication Journey Enrichment
• Data Marts

Products and services

• Zus Aggregated Profile (ZAP) The cornerstone product providing a single, shareable, always-on view of a patient that aggregates clinical data from national networks (CommonWell, Carequality, Surescripts, QHINs), pharmacy networks, lab systems, and ADT feeds into a unified patient record for care teams and healthcare organizations.
• Common Patient Record (CPR) A single, always-on view of a patient's health history powered by Zus's proprietary Universal Patient Identifier (UPID) and enterprise master patient index (eMPI) for automatic identity matching and reconciliation across different healthcare systems.
• Zus Data Marts Analytics-ready clinical data product that aggregates data from EHR systems, pharmacy fills, lab results, and ADT events, refreshed automatically every 24 hours and made available in Snowflake, Databricks, and BigQuery for population health analytics.
• Zus App Standalone Zus application providing point-of-care access to patient data, hospitalizations, transitions of care, and clinical documents for clinicians and care teams.
• Zus API & Components FHIR-based API, GraphQL endpoints, embedded components, and Zushooks (webhooks) that allow developers and healthcare technology teams to integrate Zus patient data capabilities into their own applications and EHR systems.
• Zus Platform The overarching API-driven, AI-enabled healthcare data platform from Zus Health that powers ZAP, Zus App, Zus API & Components, and EHR integrations by connecting national networks, pharmacy networks, lab systems, and ADT feeds.
• AI-Powered Risk Adjustment Comprehensive AI-powered risk adjustment solution for value-based care organizations that integrates clinical documentation and workflows to improve patient data accuracy, HCC coding, RAF score optimization, and reimbursement aligned with actual patient needs.
• Generated Patient Summary (GPS) AI-powered summarization capability that distills thousands of patient data points into concise clinical narratives for clinicians, with mandatory evidence-linking to source data, accelerating visit preparation and surfacing key insights.
• Hospitalization Summaries Care transition product that consolidates admission and discharge events into unified episodes of care, automatically retrieves and attaches clinical documentation for 70%+ of ADT events, and notifies care teams within 1 hour of ED/inpatient encounters 90%+ of the time.
• Record Locator Service Patient record retrieval service that searches across patient addresses, facility history, prescription anchors, and connected facilities to locate medical records, achieving a 96% patient match rate on record requests.

Quantifiable outcome

• 96% patient match rate on record requests
• +9 more outcomes

Named customers7 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration18 records

AI capability10 records

Feature10 records

Partnerships

13 partnerships are on record, tiered core and minor.

• Kno2coreTechnology or Integration · 11 December 2024Official QHIN partnership to enhance healthcare data exchange and interoperability. Kno2 serves as Zus's QHIN partner to support TEFCA framework implementation and national health data sharing standards.
• Elation HealthcoreTechnology or Integration · 16 March 2023Partnership to enhance data collaboration systems, allowing clinicians real-time access to comprehensive patient records through ZAP integration. Elation's EHR platform embeds Zus Aggregated Profile to surface and organize patient data into clear narrative overviews.
• athenahealthcoreTechnology or IntegrationEHR integration partner. Zus offers specific integration guidance for athenahealth customers, including initiator-only delegate listing pathway for data contribution requirements.
• Canvas MedicalcoreTechnology or IntegrationEHR integration partner with specific integration to satisfy clinical data contribution requirements.
• HealthiecoreTechnology or IntegrationEHR integration partner for care coordination and population health. Specific CCDA quality improvements and reciprocity data enhancements implemented in 2026.
• Accountable for HealthminorStrategic or Co-development PartnerZus joined as member participating in Data and Technology Committee to advocate for policies making healthcare data more actionable and accessible. Also participating in Health Care Value Week.
• CommonWell Health AlliancecoreTechnology or IntegrationNational clinical network providing broad coverage for patient records across 100,000+ facilities and 300M+ lives.
• CarequalitycoreTechnology or IntegrationNational interoperability framework enabling data exchange across healthcare networks, part of Zus's comprehensive coverage strategy.
• SurescriptscoreTechnology or IntegrationPharmacy network providing medication history data for Medication Journey Enrichment feature and comprehensive patient records.
• Bamboo HealthcoreTechnology or IntegrationADT network partner providing real-time event notifications for care coordination and hospitalization alerts.
• Collective MedicalcoreTechnology or IntegrationADT network partner (now part of Bamboo Health) for patient event notifications and care transitions management.
• Quest DiagnosticscoreTechnology or IntegrationLab network partner providing diagnostic report data integrated into patient records.
• LabcorpcoreTechnology or IntegrationLab network partner providing laboratory result data for comprehensive patient records.

Scale indicators15 records

Recent moves6 records

Expansion highlights7 records

Direct peers

• Particle Health: Particle Health operates a patient data API and record locator service that aggregates clinical records from national networks for digital health and VBC customers — directly comparable to Zus's ZAP and RLS capabilities.
• Health Gorilla: Health Gorilla is a clinical data exchange and interoperability platform with QHIN designation providing patient records, labs, and imaging data via API — competing head-to-head with Zus in TEFCA-enabled record retrieval.
• 1upHealth: 1upHealth is a FHIR-native data platform that aggregates patient records, normalizes data, and offers developer APIs for payers and providers — closely mirroring Zus's FHIR-based, developer-first approach.
• Datavant: Datavant connects health data across providers, payers, and life sciences for record exchange and real-world data — comparable in scale of network connectivity and focus on de-identified and identifiable health data flows.
• Redox: Redox provides a healthcare API integration platform that connects digital health apps to EHRs and national networks — directly comparable to Zus's API-first, EHR-embedded distribution model.

Emerging players

• Avaneer Health: Avaneer Health is a decentralized health data exchange network built by major payers and providers for TEFCA-era interoperability — a rising competitor in the same QHIN-enabled data sharing category.

Broad incumbents

• Epic Systems: Epic operates Care Everywhere and Cosmos for inter-EHR data exchange and large-scale clinical data aggregation; as the dominant EHR vendor, Epic can bundle interoperability capabilities that compete with Zus's aggregation layer.
• Athenahealth: Athenahealth offers the 'More Disruption Please' marketplace and data exchange APIs for ambulatory customers — overlapping with Zus on ambulatory EHR customers and FHIR-based integrations, and notable given founder Jonathan Bush's prior role there.

Others

• Kno2: Kno2 is a designated QHIN that enables TEFCA-based clinical exchange and is Zus's official QHIN partner — adjacent infrastructure rather than direct competitor, but a credible standalone option for customers evaluating interoperability.
• Bamboo Health: Bamboo Health provides real-time ADT event notifications and care coordination data that Zus consumes — adjacent rather than competitive, but Bamboo Health's broader behavioral health and care coordination suite overlaps with Zus's care transitions use cases.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/ZusHealthHQ
• Facebookfacebook.com/zushealthhq
• LinkedInlinkedin.com/company/zus-health

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds3 records

Investors8 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Zus Health